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Cardiac computed tomography angiography

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https://www.readbyqxmd.com/read/29454767/diagnostic-performance-of-fully-automated-pixel-wise-quantitative-myocardial-perfusion-imaging-by-cardiovascular-magnetic-resonance
#1
Li-Yueh Hsu, Matthew Jacobs, Mitchel Benovoy, Allison D Ta, Hannah M Conn, Susanne Winkler, Anders M Greve, Marcus Y Chen, Sujata M Shanbhag, W Patricia Bandettini, Andrew E Arai
OBJECTIVES: The authors developed a fully automated framework to quantify myocardial blood flow (MBF) from contrast-enhanced cardiac magnetic resonance (CMR) perfusion imaging and evaluated its diagnostic performance in patients. BACKGROUND: Fully quantitative CMR perfusion pixel maps were previously validated with microsphere MBF measurements and showed potential in clinical applications, but the methods required laborious manual processes and were excessively time-consuming...
February 9, 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29450741/utility-of-cardiac-computed-tomography-scanning-in-the-diagnosis-and-pre-operative-evaluation-of-patients-with-infective-endocarditis
#2
Jason R Sims, Nandan S Anavekar, Krishnaswamy Chandrasekaran, James M Steckelberg, Walter R Wilson, Bernard J Gersh, Larry M Baddour, Daniel C DeSimone
Transesophageal echocardiography (TEE) is the gold standard imaging study used in the diagnosis of infective endocarditis (IE). Computed tomography angiography (CTA) has undergone rapid advancement as a cardiac imaging technique and has previously shown promise in small non-randomized studies for evaluation of IE. We hypothesized that cardiac CTA would perform similarly to TEE in the detection of endocarditic lesions and that there would be no difference in clinical outcomes whether the coronary arteries were evaluated by CTA or invasive coronary angiography (ICA)...
February 15, 2018: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29447342/diagnosing-coronary-artery-disease-after-a-positive-coronary-computed-tomography-angiography-the-dan-nicad-open-label-parallel-head-to-head-randomized-controlled-diagnostic-accuracy-trial-of-cardiovascular-magnetic-resonance-and-myocardial-perfusion-scintigraphy
#3
L Nissen, S Winther, J Westra, J A Ejlersen, C Isaksen, A Rossi, N R Holm, G Urbonaviciene, L C Gormsen, L H Madsen, E H Christiansen, M Maeng, L L Knudsen, L Frost, L Brix, H E Bøtker, S E Petersen, M Bøttcher
Aims: Perfusion scans after coronary computed tomography angiography (CCTA) in patients with suspected coronary artery disease (CAD) may reduce unnecessary invasive coronary angiographies (ICAs). However, the diagnostic accuracy of perfusion scans after primary CCTA is unknown. The aim of this study was to determine the diagnostic accuracy of cardiac magnetic resonance (CMR) and myocardial perfusion scintigraphy (MPS) against ICA with fractional flow reserve (FFR) in patients suspected of CAD by CCTA...
February 13, 2018: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29446126/layer-specific-global-longitudinal-strain-reveals-impaired-cardiac-function-in-patients-with-reversible-ischemia
#4
Christoffer E Hagemann, Søren Hoffmann, Flemming J Olsen, Peter G Jørgensen, Thomas Fritz-Hansen, Jan S Jensen, Tor Biering-Sørensen
AIMS: Two-dimensional speckle tracking echocardiography (2DSTE) detects early signs of left ventricular dysfunction; however, it is unknown whether layer-specific global longitudinal strain (GLS) has incremental value in diagnosis of patients with reversible ischemia assessed by single photon emission computed tomography (SPECT). METHODS AND RESULTS: Eighty patients with stable angina pectoris (SAP), normal left ventricular ejection fraction (LVEF), and no history of ischemic heart disease were retrospectively identified to have been examined by 2DSTE, SPECT, and coronary angiography (CAG)...
February 15, 2018: Echocardiography
https://www.readbyqxmd.com/read/29444926/high-sensitivity-cardiac-troponin-i-and-the-diagnosis-of-coronary-artery-disease-in-patients-with-suspected-angina-pectoris
#5
Philip D Adamson, Amanda Hunter, Debbie M Madsen, Anoop S V Shah, David A McAllister, Tania A Pawade, Michelle C Williams, Colin Berry, Nicholas A Boon, Marcus Flather, John Forbes, Scott McLean, Giles Roditi, Adam D Timmis, Edwin J R van Beek, Marc R Dweck, Hans Mickley, Nicholas L Mills, David E Newby
BACKGROUND: We determined whether high-sensitivity cardiac troponin I can improve the estimation of the pretest probability for obstructive coronary artery disease (CAD) in patients with suspected stable angina. METHODS AND RESULTS: In a prespecified substudy of the SCOT-HEART trial (Scottish Computed Tomography of the Heart), plasma cardiac troponin was measured using a high-sensitivity single-molecule counting assay in 943 adults with suspected stable angina who had undergone coronary computed tomographic angiography...
February 2018: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/29438137/visualization-of-myocardial-infarction-in-postmortem-multiphase-computed-tomography-angiography-a-feasibility-study
#6
Sara Sabatasso, Jessica Vanhaebost, Francesco Doenz, Cristian Palmiere, Katarzyna Michaud, Fabrice Dedouit, Silke Grabherr
Recent studies have indicated that multiphase postmortem computed tomography angiography (MPMCTA) allows detection of a pathological enhancement of the myocardium in regions that correlate with the localization of the infarction at histology. The aim of this study was to verify this hypothesis by examining MPMCTA images in cases of myocardial infarction. Therefore, we investigated 10 autopsy cases where death was attributed to myocardial infarction or which showed cardiovascular pathology. As a control group, we selected 10 cases of non-natural (namely, not cardiac) death...
February 12, 2018: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/29426678/low-yield-of-extensive-workup-for-embolic-sources-in-lacunar-stroke-patients
#7
Yan Wang, Yoon Choi, Joshuae Gallardo, Ifeoma Nwaneri, James R Brorson
OBJECTIVE: We aimed to evaluate the yield of extensive etiologic workup in lacunar stroke patients. BACKGROUND: As lacunar strokes are infrequently caused by thromboembolism, the clinical relevance of extensive workup for thromboembolic sources is questioned. METHODS: Among consecutive stroke admissions to a single center over 3 years, the 100 cases initially classified as lacunar stroke and a sample of 100 cases classified as non-lacunar ischemic strokes were studied...
February 6, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29417409/a-new-method-of-ct-for-the-cardiac-measurement-correlation-of-computed-tomography-measured-cardiac-parameters-and-pulmonary-obstruction-index-to-assess-cardiac-morphological-changes-in-acute-pulmonary-embolism-patients
#8
Zhi-Jun Guo, Hai-Tao Liu, Ze-Mei Bai, Qiang Lin, Bao-Hong Zhao, Qian Xu, Yan-Hong Zeng, Wen-Qiu Feng, Hai-Tao Zhou, Fei Liang, Ji-Yan Cui
Acute pulmonary embolism (APE) is a serious disease which is life-threatening. Since it is crucial for APE patients to assess the changes of cardiac function safely and timely, the imaging research of cardiac morphology and function is becoming more and more important. The correlation of computed tomography (CT) measured cardiac parameters and pulmonary obstruction index (POI) was analyzed to discuss the morphological changes of the heart of APE patients in order to provide a new method to evaluate cardiac functions accurately and effectively...
February 7, 2018: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/29414521/association-between-epicardial-fat-volume-and-fractional-flow-reserve-an-analysis-of-the-determination-of-fractional-flow-reserve-defacto-study
#9
Ashley Beecy, Bríain Ó Hartaigh, Joshua Schulman-Marcus, Khalil Anchouche, Heidi Gransar, Subhi Al'Aref, Kimberly Elmore, Fay Y Lin, James K Min, Jessica M Peña
BACKGROUND: This study examines the relationship between epicardial fat volume (EFV) and lesion-specific ischemia by fractional flow reserve (FFR). METHODS: In a study of 173 patients (63.0 ± 8.3 years) undergoing FFR, EFV was determined using cardiac computed tomography. Relationships between EFV and FFR were assessed using multivariable linear and logistic regression. RESULTS: Using multivariable linear and logistic regression, no association between EFV and FFR was observed (β [SE] = -0...
February 2, 2018: Clinical Imaging
https://www.readbyqxmd.com/read/29409167/three-dimensional-printing-enhances-preparation-for-repair-of-double-outlet-right-ventricular-surgery
#10
Liyun Zhao, Sijie Zhou, Taibing Fan, Bin Li, Weijie Liang, Haoju Dong
OBJECTIVE: To assess the clinical value of three-dimensional (3D) printing technology for treatment strategies for complex double outlet right ventricle (DORV). METHODS: Twenty-five patients with complex double outlet right ventricle were enrolled in this study. The patients were divided into two groups: 3D printing group (eight patients) and a non-3-D printing control group (17 patients). The cardiac images of patients in the 3D printing group were transformed to Digital Imaging and Communications and were segmented and reconstructed to create a heart model...
January 2018: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/29406941/cardiac-imaging-modalities-and-appropriate-use
#11
REVIEW
Paul Gabriel Peterson, Michael Berge, John P Lichtenberger, Maureen N Hood, Vincent B Ho
Cardiovascular imaging with calcium scoring computed tomography (CT), coronary CT angiography (CCTA), and cardiac MRI (CMR) have advanced rapidly over recent years. These imaging modalities have increased in availability, accessibility, and clinical practicality due to technological advances allowing for significant radiation dose reduction for high-quality CCTA and for rapid and reliable imaging techniques in CMR. Hardware and software developments are continually increasing efficiency and accuracy of postprocessing...
March 2018: Primary Care
https://www.readbyqxmd.com/read/29398384/ultra-short-acting-%C3%AE-blockers-esmolol-and-landiolol-in-the-perioperative-period-and-in-critically-ill-patients
#12
REVIEW
Ricardo Poveda-Jaramillo, Fabrizio Monaco, Alberto Zangrillo, Giovanni Landoni
β-Blockers are useful drugs in several clinical cardiologic scenarios. Their use in the perioperative period and in critically ill patients is increasing, but their effect on clinically relevant outcomes remains controversial. Long-acting β-blockers can have detrimental effects that are difficult to be counteracted in these settings. The authors describe the possible clinical uses of ultra-short-acting β-blockers (esmolol and landiolol) in the perioperative period and in critically ill patients because these drugs have the beneficial effects of β-blockers, but do not have the detrimental effects of long-acting agents...
November 23, 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29396194/low-thigh-muscle-mass-is-associated-with-coronary-artery-stenosis-among-hiv-infected-and-hiv-uninfected-men-the-multicenter-aids-cohort-study-macs
#13
Martin Tibuakuu, Di Zhao, Ankita Saxena, Todd T Brown, Lisa P Jacobson, Frank J Palella, Mallory D Witt, Susan L Koletar, Joseph B Margolick, Eliseo Guallar, Sai Krishna C Korada, Matthew J Budoff, Wendy S Post, Erin D Michos
BACKGROUND: HIV-infected individuals are at increased risk for both sarcopenia and cardiovascular disease. Whether an association between low muscle mass and subclinical coronary artery disease (CAD) exists, and if it is modified by HIV serostatus, are unknown. METHODS: We performed cross-sectional analysis of 513 male MACS participants (72% HIV-infected) who underwent mid-thigh computed tomography (CT) and non-contrast cardiac CT for coronary artery calcium (CAC) during 2010-2013...
January 30, 2018: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/29387923/association-between-histological-features-of-epicardial-adipose-tissue-and-coronary-plaque-characteristics-on-computed-tomography-angiography
#14
Atsuhiro Senoo, Toshiro Kitagawa, Shinya Torimaki, Hideya Yamamoto, Kazuhiro Sentani, Shinya Takahashi, Yumiko Kubo, Wataru Yasui, Taijiro Sueda, Yasuki Kihara
The means by which epicardial adipose tissue (EAT) could influence coronary plaque progression biologically remain unclear. We investigated the association between the histological findings of EAT and coronary plaque characteristics assessed by coronary computed tomography angiography (CCTA). We enrolled 34 patients in whom one or more coronary plaques containing non-calcified components were detected on CCTA before cardiac surgery [coronary artery bypass graft (CABG) or non-CABG]. We evaluated visceral adipose tissue (VAT) area, EAT volume, and coronary plaque characteristics including minimum computed tomography density (CTD) and vascular Remodeling Index (RI)...
January 31, 2018: Heart and Vessels
https://www.readbyqxmd.com/read/29384863/myocardial-perfusion-at-rest-in-uncomplicated-type-2-diabetes-patients-without-coronary-artery-disease-evaluated-by-320-multidetector-computed-tomography-a-pilot-study
#15
Xiangyi Cai, Shuihua Zhang, Dabiao Deng, Honglin Li, Xueqing Guan, Jin Fang, Quan Zhou
Using computed tomography myocardial perfusion imaging (CTP) to investigate resting myocardial perfusion alterations in uncomplicated type 2 diabetes mellitus (T2DM) patients without obstructive coronary artery disease (CAD).A total of 34 participants with 544 myocardial segments were included prospectively: 17 uncomplicated T2DM patients with no significant coronary artery stenosis on coronary computed tomography angiography and 17 healthy controls. Myocardial perfusion was evaluated by transmural perfusion ratio (TPR)...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29382393/modified-double-patch-repair-with-infarct-exclusion-technique-for-ventricular-septal-perforation-a-case-study
#16
Takuma Yamasaki, Shuhei Fujita, Yuji Kaku, Junko Katagiri, Takeshi Hiramatsu
BACKGROUND: Ventricular septal perforation (VSP) after acute myocardial infarction (AMI) is accompanied by the worsening of rapid hemodynamics, resulting in a poor prognosis. In our department, infarct lesions are preoperatively detected with electrocardiogram (ECG)-synchronized contrast computed tomography, and the scope of approach and exclusion is determined. Furthermore, to effectively prevent a residual shunt, modified double patch repair and infarct exclusion techniques were used in combination to preserve left ventricular (LV) function...
January 30, 2018: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/29374188/impact-of-left-atrial-appendage-morphology-on-thrombus-formation-after-successful-left-atrial-appendage-occlusion-assessment-with-cardiac-computed-tomography
#17
Wulf Dieker, Michael Behnes, Christian Fastner, Benjamin Sartorius, Annika Wenke, Ishar Sing-Gill, Ibrahim El-Battrawy, Jürgen Kuschyk, Theano Papavassiliu, Ursula Hoffmann, Kambis Mashayekhi, Stefan O Schoenberg, Martin Borggrefe, Thomas Henzler, Ibrahim Akin
A standardized imaging algorithm by cardiac computed tomography angiography (cCTA) (LOVE-view) was used in 30 patients to evaluate the influence of different left atrial appendage (LAA) morphologies on development of thrombosis in the LAA 6 months after implantation of an occlusion device (Watchman or Amplatzer-Cardiac-Plug) in patients with non-valvular atrial fibrillation, CHA2DS2-VASc-Score >1 and a contraindication for oral anticoagulation. The distribution of different LAA morphologies was 40% windsock, 17% broccoli and 43% chicken wing type...
January 26, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29361983/cardiac-computed-tomography-in-patients-with-symptomatic-new-onset-atrial-fibrillation-rule-out-acute-coronary-syndrome-but-with-intermediate-pretest-probability-for-coronary-artery-disease-admitted-to-a-chest-pain-unit
#18
Matthias Koopmann, Liane Hinrichs, Jan Olligs, Michael Lichtenberg, Lars Eckardt, Dirk Böse, Stefan Möhlenkamp, Johannes Waltenberger, Frank Breuckmann
BACKGROUND: Atrial fibrillation (AF) and coronary artery disease (CAD) may be encountered coincidently in a large portion of patients. However, data on coronary artery calcium burden in such patients are lacking. Thus, we sought to determine the value of cardiac computed tomography (CCT) in patients presenting with new-onset AF associated with an intermediate pretest probability for CAD admitted to a chest pain unit (CPU). METHODS: Calcium scores (CS) of 73 new-onset, symptomatic AF subjects without typical clinical, electrocardiographic, or laboratory signs of acute coronary syndrome (ACS) admitted to our CPU were analyzed...
January 24, 2018: European Journal of Medical Research
https://www.readbyqxmd.com/read/29351655/establishing-diagnostic-reference-levels-for-cardiac-computed-tomography-angiography-in-saudi-arabia
#19
Ali B Alhailiy, Peter L Kench, Mark F McEntee, Patrick C Brennan, Elaine A Ryan
Cardiac computed tomography angiography (CCTA) is a commonly used diagnostic imaging tool for cardiovascular disease. Despite constant improvements to imaging technologies, the radiation dose to patients remains a concern when using this procedure. Diagnostic reference levels (DRLs) are used as a trigger to identify and alert individual facilities that are using high doses during CT. This study aims to assess patient radiation dose and establish new national DRLs (NDRL) associated with CCTA in Saudi clinical practices...
January 17, 2018: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/29351615/18f-fluorodeoxyglucose-positron-emission-computed-tomography-and-computed-tomography-angiography-in-prosthetic-heart-valve-endocarditis-from-guidelines-to-clinical-practice
#20
Laurens E Swart, Asbjørn M Scholtens, Wilco Tanis, Koen Nieman, Ad J J C Bogers, Fred J Verzijlbergen, Gabriel P Krestin, Jolien W Roos-Hesselink, Ricardo P J Budde
The timely diagnosis of prosthetic heart valve endocarditis remains challenging yet of utmost importance. 18F-fluorodeoxyglucose (18 F-FDG) positron emission/computed tomography (PET/CT) and cardiac computed tomography angiography (CTA) were recently introduced as additional diagnostic tools in the most recent ESC guidelines on infective endocarditis. However, how to interpret PET/CT findings with regard to what is to be considered abnormal, what the potential confounders may be, as well as which patients benefit most from these additional imaging techniques and how to best perform them in these often-complex patients, remains unclear...
January 16, 2018: European Heart Journal
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