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Cardiac computed tomography angiography

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https://www.readbyqxmd.com/read/28729409/comparison-of-anatomic-and-clinical-outcomes-in-patients-undergoing-alternative-initial-noninvasive-testing-strategies-for-the-diagnosis-of-stable-coronary-artery-disease
#1
Idan Roifman, Harindra C Wijeysundera, Peter C Austin, Mohammad R Rezai, Graham A Wright, Jack V Tu
BACKGROUND: The optimal initial noninvasive diagnostic testing strategy for stable coronary artery disease (CAD) is unknown. Although American guidelines recommend an exercise stress test as the first-line test, European guidelines suggest that stress imaging (myocardial perfusion imaging or stress echocardiography) or coronary computed tomography angiography may be preferable. Understanding the relationship between the initial strategy and downstream yield of obstructive CAD and major adverse cardiac events may provide insight as to the optimal strategy...
July 19, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28728443/functional-assessment-of-coronary-artery-disease-by-cardiac-computed-tomography
#2
T A Treibel, A Rossi, F Pugliese, C Davies
Rapid technological advances in computed tomography (CT) have allowed CT coronary angiography (CTCA) to be delivered at low radiation dose and high diagnostic accuracy. Due to its high negative predictive value for coronary artery disease, it has become a gatekeeper for the assessment of patients with chest pain of recent onset. Second line functional assessment of a detected coronary stenosis relies mostly on other imaging modalities. Functional assessment of coronary artery disease by CT is therefore an attractive addition to CTCA...
July 21, 2017: Expert Review of Cardiovascular Therapy
https://www.readbyqxmd.com/read/28725938/declining-radiation-dose-of-coronary-computed-tomography-angiography-german-cardiac-ct-registry-experience-2009-2014
#3
Axel Schmermund, Mohamed Marwan, Jörg Hausleiter, Sebastian Barth, Oliver Bruder, Sebastian Kerber, Grigorius Korosoglou, Alexander Leber, Werner Moshage, Stephen Schröder, Steffen Schneider, Jochen Senges, Stephan Achenbach
BACKGROUND: Coronary computed tomography angiography (CTA) is increasingly used as a test to rule out coronary artery disease (CAD) in patients with a low to intermediate pre-test probability of the disease. We used the database of the German CT registry, collected between 2009 and 2014 in a broad patient population, to analyze contemporary radiation dose associated with coronary CTA in clinical practice. PATIENTS AND METHODS: The prospective observational registry included a total of 7061 patients ≥18 years, referred to 12 participating centers for a clinically indicated cardiac CT examination...
July 19, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28720123/cardiovascular-magnetic-resonance-in-an-adult-human-population-serial-observations-from-the-multi-ethnic-study-of-atherosclerosis
#4
REVIEW
Kihei Yoneyama, Bharath A Venkatesh, David A Bluemke, Robyn L McClelland, João A C Lima
The Multi-Ethnic Study of Atherosclerosis (MESA) is the first large-scale multi-ethnic population study in the U.S. to use advanced cardiovascular magnetic resonance (CMR) imaging. MESA participants were free of cardiovascular disease at baseline between 2000 and 2002, and were followed up between 2009 and 2011 with repeated CMR examinations as part of MESA. CMR allows the clinician to visualize and accurately quantify volume and dimensions of all four cardiac chambers; measure systolic and diastolic ventricular function; assess myocardial fibrosis; assess vessel lumen size, vessel wall morphology, and vessel stiffness...
July 18, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28719492/fifty-men-3510-marathons-cardiac-risk-factors-and-coronary-artery-calcium-scores
#5
William O Roberts, Robert S Schwartz, Ross F Garberich, Samantha Carlson, Thomas Knickelbine, Jonathan G Schwartz, Gretchen Peichel, John R Lesser, Kelly Wickstrom, Kevin M Harris
INTRODUCTION/PURPOSE: Many male marathon runners have elevated coronary artery calcium (CAC) scores despite high physical activity. We examined the association between CAC scores, cardiovascular risk factors, and lifestyle habits in long term marathoners. METHODS: We recruited men who had run ≥1 marathon annually for 25 consecutive years. CAC was assessed using coronary computed tomography angiography. Atherosclerotic cardiovascular disease (CAD) risk factors were measured with a 12-lead ECG, serum lipid panel, height, weight, resting blood pressure and heart rate, and a risk factor questionnaire...
July 17, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28713813/incidental-finding-of-an-aorto-right-atrial-fistula-in-a-patient-undergoing-repair-of-a-sinus-of-valsalva-aneurysm
#6
Byron R Rosero-Britton, Anthony Nguyen, Ibrahim Warsame, Muhammad Shabsigh, Luke Dong, James Wolfe, Bryan Whitson, Michael Essandoh
A sinus of Valsalva aneurysm is a rare malformation of the aortic root that can fistulize to another cardiac structure such as the right atrium. Although transthoracic echocardiography and computed tomography angiography have demonstrated utility for the diagnosis of a sinus of Valsalva-to-right atrial fistula, there are few cases where a misdiagnosis may occur. Intraoperative transesophageal echocardiography may be an essential imaging tool for the diagnosis and management of incidental findings such as a sinus of Valsalva-to-right atrial fistula during cardiac surgery and should be used routinely...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/28702479/image-quality-and-contrast-agent-exposure-in-cardiac-computed-tomography-angiography-prior-to-transcatheter-aortic-valve-implantation-procedures-using-different-acquisition-protocols
#7
Nina P Hofmann, Moritz Schuetz, Raffi Bekeredjian, Sven Pleger, Emanuel Chorianopoulos, Sorin Giusca, Florian André, Gitsios Gitsioudis, Christopher Schlett, Hans-Ulrich Kauczor, Hugo A Katus, Grigorios Korosoglou
BACKGROUND: ECG-gated cardiac computed tomography angiography (CCTA) has found widespread use for prosthesis sizing before transcatheter aortic valve implantation (TAVI). However, still little data exists on the optimal scan-strategy in such patients. We hypothesized that prospectively triggered CCTA can enable the visualization of aortic valve structures and peripheral arteries with lower radiation and contrast agent exposure in patients considered for TAVI compared to retrospectively gated protocols...
2017: European Journal of Radiology Open
https://www.readbyqxmd.com/read/28690294/unusual-coronary-sinus-tumor-in-a-pregnant-woman
#8
Guang Song, Jing Liu, Baosheng Guo, Feifei Sun, Weidong Ren, Fangfang Li, Wanying Huang
Primary coronary sinus tumors are extremely rare. Herein, we present a case of a pregnant woman with a primary myxoma in the coronary sinus (CS), which was diagnosed by echocardiography and computed tomography. We reviewed the literature and found two other primary CS tumors. We summarized the gender, ages, symptoms, diagnostic methods, associated anomalies, treatments, histologic findings, and outcomes of the 3 cases. Dyspnea was a common symptom of all 3 patients. Diagnostic methods included echocardiography, computed tomography, magnetic resonance imaging, and coronary angiography...
July 10, 2017: International Heart Journal
https://www.readbyqxmd.com/read/28685252/imaging-the-event-prone-coronary-artery-plaque
#9
Andreas A Giannopoulos, Dominik C Benz, Christoph Gräni, Ronny R Buechel
Acute coronary events, the dreaded manifestation of coronary atherosclerosis, remain one of the main contributors to mortality and disability in the developed world. The majority of those events are associated with atherosclerotic plaques-related thrombus formation following an acute disruption, that being rupture or erosion, of an event-prone lesion. These historically termed vulnerable plaques have been the target of numerous benchtop and clinical research endeavors, yet to date without solid results that would allow for early identification and potential treatment...
July 6, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28674321/incremental-prognostic-value-of-coronary-computed-tomography-angiography-high-risk-plaque-characteristics-in-asymptomatic-patients
#10
Kazuhisa Takamura, Shinichiro Fujimoto, Takeshi Kondo, Makoto Hiki, Yuko Kawaguchi, Etsuro Kato, Hiroyuki Daida
AIM: Coronary computed tomography angiography (CCTA) findings of positive remodeling (index >1.1) and low-attenuation plaque (<30 Hounsfield units) are recognized as CT-verified high-risk plaque (CT-HRP). Therefore, we investigated the incremental prognostic value of evaluation of plaque characteristics using CCTA in asymptomatic patients. METHODS: Overall, 495 consecutive patients without any known coronary artery disease who underwent CCTA were included in this study...
July 1, 2017: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/28673032/non-invasive-management-of-post-partum-spontaneous-left-main-coronary-artery-dissection-using-cardiac-computed-tomography-angiography
#11
Avinoam Shiran, Salim Adawi, Ronen Rubinshtein, Mordechai Bardicef, Eli Gutterman
No abstract text is available yet for this article.
June 30, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28672916/diagnostic-accuracy-of-coronary-ct-angiography-combined-with-dual-energy-myocardial-perfusion-imaging-for-detection-of-myocardial-infarction
#12
Ruijuan Han, Kai Sun, Bin Lu, Ruiping Zhao, Kuncheng Li, Xinchun Yang
The aim of the present study was to evaluate the diagnostic accuracy of second generation dual-energy computed tomography (DECT) myocardial perfusion imaging for the detection of myocardial infarction (MI) in patients with suspected MI. In total, 56 patients underwent DECT. Among those, 40 patients had MI that was detected by catheter coronary angiography and cardiac troponin I elevation and evolution of acute MI detected by electrocardiogram changes. The diagnostic accuracy, including the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) for the detection of MI were evaluated, as well as the coronary image quality of coronary artery and radiation dose...
July 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28670826/current-practices-are-variable-in-the-evaluation-and-management-of-patients-with-anomalous-aortic-origin-of-a-coronary-artery-results-of-a-survey
#13
Hitesh Agrawal, Carlos M Mery, Patrick E Day, S Kristen Sexson Tejtel, E Dean McKenzie, Charles D Fraser, Athar M Qureshi, Silvana Molossi
BACKGROUND: Anomalous aortic origin of a coronary artery (AAOCA) is the second leading cause of sudden cardiac death in young athletes in the USA. Long-term outcome data for these patients are lacking to date. There is insufficient knowledge on the best approach to these patients and they are managed in a nonuniform manner. METHODS: An online survey of 15 questions regarding management of AAOCA was sent out to 198 cardiac healthcare providers. The goal was to define gaps in knowledge to justify a dedicated scientific forum for discussion of AAOCA...
July 2, 2017: Congenital Heart Disease
https://www.readbyqxmd.com/read/28670160/assessment-of-myocardial-bridge-by-cardiac-ct-intracoronary-transluminal-attenuation-gradient-derived-from-diastolic-phase-predicts-systolic-compression
#14
Mengmeng Yu, Yang Zhang, Yuehua Li, Minghua Li, Wenbin Li, Jiayin Zhang
OBJECTIVE: To study the predictive value of transluminal attenuation gradient (TAG) derived from diastolic phase of coronary computed tomography angiography (CCTA) for identifying systolic compression of myocardial bridge (MB). MATERIALS AND METHODS: Consecutive patients diagnosed with MB based on CCTA findings and without obstructive coronary artery disease were retrospectively enrolled. In total, 143 patients with 144 MBs were included in the study. Patients were classified into three groups: without systolic compression, with systolic compression < 50%, and with systolic compression ≥ 50%...
July 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/28667489/in-vivo-visualization-of-braid-like-appearance-in-kawasaki-disease-insights-from-multi-modality-imaging
#15
Hiroki Nakano, Yu Kataoka, Satoshi Yasuda
A 42-year-old gentleman with Kawasaki disease was referred for silent cardiac ischemia at inferior myocardial region. Coronary angiography showed braid-like appearance in the right coronary artery. Several channels at the segment with braid-like appearance were visualized by multi-slice computed tomography and intravascular ultrasound. Interestingly in particular, optical coherence tomography visualized the presence of multiple micro-vessels which were not detectable on other modalities. This case further elucidates distinct morphological features of braid-like lesion which potentially influences blood supply and causing cardiac ischemia...
June 30, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28663663/design-optimization-for-accurate-flow-simulations-in-3d-printed-vascular-phantoms-derived-from-computed-tomography-angiography
#16
Kelsey Sommer, Richard L Izzo, Lauren Shepard, Alexander R Podgorsak, Stephen Rudin, Adnan H Siddiqui, Michael F Wilson, Erin Angel, Zaid Said, Michael Springer, Ciprian N Ionita
3D printing has been used to create complex arterial phantoms to advance device testing and physiological condition evaluation. Stereolithographic (STL) files of patient-specific cardiovascular anatomy are acquired to build cardiac vasculature through advanced mesh-manipulation techniques. Management of distal branches in the arterial tree is important to make such phantoms practicable. We investigated methods to manage the distal arterial flow resistance and pressure thus creating physiologically and geometrically accurate phantoms that can be used for simulations of image-guided interventional procedures with new devices...
February 11, 2017: Proceedings of SPIE
https://www.readbyqxmd.com/read/28657113/high-burden-of-coronary-atherosclerosis-in-patients-with-cirrhosis
#17
Konstantin Kazankov, Kim Munk, Kristian Altern Øvrehus, Jesper Møller Jensen, Cecilie Brøckner Siggaard, Henning Grønbaek, Bjarne Linde Nørgaard, Hendrik Vilstrup
BACKGROUND: Population studies report increased cardiovascular mortality in patients with cirrhosis. Coronary artery disease may be a trait of end-stage liver disease, but whether it is frequent or extensive in cirrhosis in general is unknown. Thus, we aimed to assess the prevalence and extent of coronary artery disease in unselected cirrhosis patients. MATERIALS AND METHODS: Using coronary computed tomography angiography, we investigated 52 patients from all Child-Pugh classes and etiologies of cirrhosis without known cardiac disease for presence and severity of coronary artery disease in a cross-sectional design...
June 28, 2017: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28654385/3d-fusion-framework-for-infarction-and-angiogenesis-analysis-in-a-myocardial-infarct-minipig-model
#18
Xu Zhenzhen, Bo Tao, Yu Li, Jun Zhang, Xiaochao Qu, Feng Cao, Jimin Liang
The combination of different modality images can provide detailed and comprehensive information for the prognostic assessment and therapeutic strategy of patients with ischemic heart disease. In this study, a 3D fusion framework is designed to integrate coronary computed tomography (CT) angiography (CTA), 2-deoxy-2-[(18)F]fluoro-D-glucose ([(18)F]DG) positron emission tomography (PET)/CT, and [(68)Ga]-1,4,7-triazacyclononane-1,4,7-triacetic acid-(Arg-Gly-Asp)2 ([(68)Ga]-NOTA-PRGD2) PET/CT images of the myocardial infarction model in minipigs...
January 1, 2017: Molecular Imaging
https://www.readbyqxmd.com/read/28648482/comparison-of-intravascular-ultrasound-and-centerline-computed-tomography-determined-aortic-diameters-during-thoracic-endovascular-aortic-repair
#19
Sukgu M Han, Ramsey S Elsayed, Sung W Ham, Anuj Mahajan, Fernando Fleischman, Vincent L Rowe, Mark J Cunningham, Fred A Weaver
BACKGROUND: Accurate sizing of stent grafts during thoracic endovascular aortic repair (TEVAR) is critical for a successful outcome. Centerline measurements using three-dimensional reconstruction of preoperative computed tomography angiography (CTA) is the current standard for stent graft sizing. However, this technique is predicated on an idealized straightened aorta and does not account for the variability in the aortic diameter during the cardiac cycle or the overall status of the patient's volume...
June 22, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28639400/motion-estimation-for-cardiac-functional-analysis-using-two-x-ray-computed-tomography-scans
#20
George S K Fung, Luisa Ciuffo, Hiroshi Ashikaga, Katsuyuki Taguchi
PURPOSE: This work concerns computed tomography (CT)-based cardiac functional analysis (CFA) with a reduced radiation dose. As CT-CFA requires images over the entire heartbeat, the scans are often performed at 10-20% of the tube current settings that are typically used for coronary CT angiography. A large image noise then degrades the accuracy of motion estimation. Moreover, even if the scan was performed during the sinus rhythm, the cardiac motion observed in CT images may not be cyclic with patients with atrial fibrillation...
June 22, 2017: Medical Physics
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