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Hepatitis c north carolina

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https://www.readbyqxmd.com/read/27168668/hepatitis-c-virus-testing-and-linkage-to-care-in-north-carolina-and-south-carolina-jails-2012-2014
#1
Ben T Schoenbachler, Bryce D Smith, Arlene C Seña, Alison Hilton, Sallie Bachman, Mulamba Lunda, Anne C Spaulding
OBJECTIVE: We evaluated a hepatitis C virus (HCV) testing and linkage-to-care post-release program among detainees of small- to medium-sized jails in North Carolina and South Carolina as part of the Hepatitis Testing and Linkage to Care initiative. METHODS: An HCV testing and linkage-to-care program was implemented in selected jails in North Carolina and South Carolina from December 2012 to March 2014. Health-care workers not affiliated with the jails conducted HCV antibody (anti-HCV) and HCV ribonucleic acid (RNA) testing and linkage-to-care activities...
May 2016: Public Health Reports
https://www.readbyqxmd.com/read/27168663/efforts-at-the-frontlines-implementing-a-hepatitis-c-testing-and-linkage-to-care-program-at-the-local-public-health-level
#2
Arlene C Seña, Sarah J Willis, Alison Hilton, Alexandria Anderson, David A Wohl, Christopher B Hurt, Andrew J Muir
OBJECTIVES: The national Viral Hepatitis Action Plan recommends strengthening partnerships among health departments, community-based organizations, and health-care providers for hepatitis services. We implemented a hepatitis C virus (HCV) testing and linkage-to-care program through a local health department using similar strategies reported for HIV care. METHODS: The Durham County Department of Public Health received federal funding to conduct HCV testing and linkage to care in Durham, North Carolina...
May 2016: Public Health Reports
https://www.readbyqxmd.com/read/27154888/hepatitis-c-in-north-carolina-two-epidemics-with-one-public-health-response
#3
Sarah Rhea, Aaron Fleischauer, Evelyn Foust, Megan Davies
No abstract text is available yet for this article.
May 2016: North Carolina Medical Journal
https://www.readbyqxmd.com/read/26981174/non-initiation-of-hepatitis-c-virus-antiviral-therapy-in-patients-with-human-immunodeficiency-virus-hepatitis-c-virus-co-infection
#4
Christine U Oramasionwu, Angela Dm Kashuba, Sonia Napravnik, David A Wohl, Lu Mao, Adaora A Adimora
AIM: To assess whether reasons for hepatitis C virus (HCV) therapy non-initiation differentially affect racial and ethnic minorities with human immunodeficiency virus (HIV)/HCV co-infection. METHODS: Analysis included co-infected HCV treatment-naïve patients in the University of North Carolina CFAR HIV Clinical Cohort (January 1, 2004 and December 31, 2011). Medical records were abstracted to document non-modifiable medical (e.g., hepatic decompensation, advanced immunosuppression), potentially modifiable medical (e...
March 8, 2016: World Journal of Hepatology
https://www.readbyqxmd.com/read/25055845/safety-climate-and-use-of-personal-protective-equipment-and-safety-medical-devices-among-home-care-and-hospice-nurses
#5
Jack K Leiss
Use of personal protective equipment (PPE) and safety medical devices is mandated for healthcare workers to reduce the risk of infection with human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) from exposure to patients' blood. Research has shown that a strong safety climate may promote increased use of PPE. Therefore, the objective of this study was to examine the association between safety climate and use of PPE among homecare/hospice nurses in North Carolina. To this end, a mail survey was conducted in 2006...
2014: Industrial Health
https://www.readbyqxmd.com/read/25023159/hepatitis-c-virus-screening-practices-and-seropositivity-among-us-veterans-born-during-1945-1965
#6
Emily J Cartwright, Christopher Rentsch, David Rimland
BACKGROUND: The Centers for Disease Control and Prevention (CDC) and the United States Preventive Services Task Force (USPSTF) recently augmented risk-based hepatitis C (HCV) screening guidelines with a recommendation to perform one-time screening in all persons born during 1945 - 1965, a birth cohort known to have a higher prevalence of HCV. We sought to estimate the proportion of veterans seen at the Atlanta VA Medical Center (AVAMC) who had ever been screened for HCV infection by birth year...
2014: BMC Research Notes
https://www.readbyqxmd.com/read/24512462/community-based-hcv-screening-knowledge-and-attitudes-in-a-high-risk-urban-population
#7
Brianna L Norton, Corrine I Voils, Sarah H Timberlake, Emily J Hecker, Neela D Goswami, Kim M Huffman, Anneka Landgraf, Susanna Naggie, Jason E Stout
BACKGROUND: In an attempt to curtail the rising morbidity and mortality from undiagnosed HCV (hepatitis C virus) in the United States, screening guidelines have been expanded to high-risk individuals and persons born 1945-1965. Community-based screening may be one strategy in which to reach such persons; however, the acceptance of HCV testing, when many high-risk individuals may not have access to HCV specific medications, remains unknown. METHODS: We set out to assess attitudes about HCV screening and knowledge about HCV disease at several community-based testing sites that serve high-risk populations...
2014: BMC Infectious Diseases
https://www.readbyqxmd.com/read/24458137/hepatic-safety-and-tolerability-of-raltegravir-among-hiv-patients-coinfected-with-hepatitis-b-and-or-c
#8
Christopher B Hurt, Sonia Napravnik, Richard D Moore, Joseph J Eron
BACKGROUND: Potential liver toxicity is an important consideration for antiretroviral selection among patients coinfected with HIV and viral hepatitis (B and/or C). We sought to describe the hepatic safety profile of raltegravir in this population. METHODS: Using data from HIV clinical cohorts at Johns Hopkins University and the University of North Carolina at Chapel Hill, we evaluated factors associated with liver enzyme elevations (LEEs) and calculated adverse event incidence rates for patients initiated on raltegravir-containing regimens prior to 1 January 2010...
2014: Antiviral Therapy
https://www.readbyqxmd.com/read/24178362/large-scale-screening-of-human-sera-for-hcv-rna-and-gbv-c-rna
#9
Jessica R Keys, Peter A Leone, Joseph J Eron, Kelcie Alexander, Myra Brinson, Ronald Swanstrom
North Carolina locates acute HIV cases by pooled nucleic acid testing of HIV-antibody negative serum samples. Here, 224 pools of 80 HIV-negative samples (N = 17,920) were screened for viral RNA from HCV, GBV-C, and influenza A. No evidence of influenza A was found, but HCV and GBV-C were common (1.2% and 1.7% prevalence, respectively), demonstrating the utility of pooled testing in locating individuals that may remain undiagnosed otherwise. By sequencing positive pools, potential transmission clusters may be located as well...
March 2014: Journal of Medical Virology
https://www.readbyqxmd.com/read/23872994/results-of-a-pilot-test-of-a-brief-computer-assisted-tailored-hiv-prevention-intervention-for-use-with-a-range-of-demographic-and-risk-groups
#10
RANDOMIZED CONTROLLED TRIAL
William A Zule, Georgiy V Bobashev, Susan M Reif, Winona Poulton, Curtis M Coomes, Wendee M Wechsberg
There is a need for brief HIV prevention interventions that can be disseminated and implemented widely. This article reports the results of a small randomized field experiment that compared the relative effects of a brief two-session counselor-delivered computer-tailored intervention and a control condition. The intervention is designed for use with African-American, non-Hispanic white and Hispanic males and females who may be at risk of HIV through unprotected sex, selling sex, male to male sex, injecting drug use or use of stimulants...
November 2013: AIDS and Behavior
https://www.readbyqxmd.com/read/23739075/acute-hepatitis-b-outbreaks-in-2-skilled-nursing-facilities-and-possible-sources-of-transmission-north-carolina-2009-2010
#11
Arlene C Seña, Anne Moorman, Levi Njord, Roxanne E Williams, James Colborn, Yury Khudyakov, Jan Drobenuic, Guo-Liang Xia, Hattie Wood, Zack Moore
OBJECTIVE: Acute hepatitis B virus (HBV) infections have been reported in long-term care facilities (LTCFs), primarily associated with infection control breaks during assisted blood glucose monitoring. We investigated HBV outbreaks that occurred in separate skilled nursing facilities (SNFs) to determine factors associated with transmission. DESIGN: Outbreak investigation with case-control studies. SETTING: Two SNFs (facilities A and B) in Durham, North Carolina, during 2009-2010...
July 2013: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/23442840/surveillance-for-hepatocellular-carcinoma-in-a-medicaid-cirrhotic-population
#12
Lena B Palmer, Michael D Kappelman, Robert S Sandler, Paul H Hayashi
GOALS: To estimate the hepatocellular carcinoma surveillance in the Medicaid cirrhotic population. BACKGROUND: Most studies predate 2005 American Association for the Study of Liver Diseases surveillance recommendations and do not examine the primary target population, cirrhotics. STUDY: From 2006 to 2007, we identified adults with at least 1 cirrhosis International Classification of Disease code and 15 months of continuous enrollment in North Carolina Medicaid, recording claims for abdominal ultrasound, computed tomography, magnetic resonance imaging, and α-fetoprotein testing...
September 2013: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/22523850/the-increasing-impact-of-human-immunodeficiency-virus-infections-sexually-transmitted-diseases-and-viral-hepatitis-in-durham-county-north-carolina-a-call-for-coordinated-and-integrated-services
#13
Marc Kolman, Mary DeCoster, Rae Jean Proeschold-Bell, Genevieve Ankeny Hunter, John Bartlett, Arlene C Seña
BACKGROUND: Durham County, North Carolina, faces high rates of human immunodeficiency virus (HIV) infection (with or without progression to AIDS) and sexually transmitted diseases (STDs). We explored the use of health care services and the prevalence of coinfections, among HIV-infected residents, and we recorded community perspectives on HIV-related issues. METHODS: We evaluated data on diagnostic codes, outpatient visits, and hospitalizations for individuals with HIV infection, STDs, and/or hepatitis B or C who visited Duke University Hospital System (DUHS)...
November 2011: North Carolina Medical Journal
https://www.readbyqxmd.com/read/21665509/association-of-pnpla3-snp-rs738409-with-liver-density-in-african-americans-with-type-2-diabetes-mellitus
#14
A J Cox, M R Wing, J J Carr, R C Hightower, S C Smith, J Xu, L E Wagenknecht, D W Bowden, B I Freedman
AIM: Non-alcoholic fatty liver disease (NAFLD) is commonly diagnosed in patients with obesity and type 2 diabetes mellitus (T2DM), and has been associated with the single nucleotide polymorphism (SNP) rs738409 in the PNPLA3 gene. This association remains to be investigated in African Americans with T2DM, a group at lower risk for hepatic steatosis relative to European Americans with T2DM. METHODS: We examined 422 African Americans with T2DM (40.3% male; age: 56...
November 2011: Diabetes & Metabolism
https://www.readbyqxmd.com/read/21529725/transmission-of-hepatitis-c-virus-during-myocardial-perfusion-imaging-in-an-outpatient-clinic
#15
Zack S Moore, Melissa K Schaefer, Karen K Hoffmann, Susan C Thompson, Guo-Liang Xia, Yulin Lin, Yury Khudyakov, Jean-Marie Maillard, Jeffrey P Engel, Joseph F Perz, Priti R Patel, Nicola D Thompson
Reports of health care--associated viral hepatitis transmission have been increasing in the United States. Transmission due to poor infection control practices during myocardial perfusion imaging (MPI) has not previously been reported. The aim of this study was to identify the source of incident hepatitis C virus (HCV) infection in a patient without identified risk factors who had undergone MPI 6 weeks before diagnosis. Practices at the cardiology clinic and nuclear pharmacy were evaluated, and HCV testing was performed in patients with shared potential exposures...
July 1, 2011: American Journal of Cardiology
https://www.readbyqxmd.com/read/20691606/use-of-yttrium-90-microspheres-in-patients-with-advanced-hepatocellular-carcinoma-and-portal-vein-thrombosis
#16
Andrea Lan Tsai, Charles T Burke, Andrew S Kennedy, Dominic T Moore, Matthew A Mauro, Robert D Dixon, Joseph M Stavas, Stephen A Bernard, Amir H Khandani, Bert H O'Neil
PURPOSE: Patients with portal vein thrombosis (PVT) and hepatocellular carcinoma (HCC) have limited treatment options because of increased disease burden and diminished hepatic perfusion. Yttrium-90 ((90)Y) microspheres may be better tolerated than chemoembolization in these patients. The present study reviews the safety and efficacy of (90)Y microspheres in HCC with major PVT. MATERIALS AND METHODS: A retrospective review of HCC with main (n = 10) or first-branch (n = 12) PVT treated with (90)Y microspheres (N = 22) was conducted...
September 2010: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/20189830/transjugular-biopsy-results-in-the-transplanted-liver-comparison-of-two-surgical-hepatic-venous-anastomotic-configurations-in-269-consecutive-biopsies-over-a-14-year-period
#17
COMPARATIVE STUDY
Michael J Miller, Tony P Smith, Paul C Kuo, Kenneth K Hirasaki, Paul V Suhocki
PURPOSE: To compare the results of transjugular liver biopsy in patients who have undergone liver transplantation via an inline versus a "piggyback" hepatic venous surgical anastomosis. MATERIALS AND METHODS: From October 1994 to July 2008 (165 months), 269 consecutive transjugular liver biopsy procedures were performed on 139 patients (94 male patients underwent 194 procedures) who had received cadaveric liver transplantation. Mean patient age at the time of the biopsy was 46...
April 2010: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/20071593/virological-rather-than-host-factors-are-associated-with-transaminase-levels-among-hiv-hcv-coinfected-patients
#18
MULTICENTER STUDY
Nathan J Shores, Ivana Maida, Leticia Perez-Saleme, Marina Núñez
Alanine aminotransferase (ALT) is a routine parameter in the assessment and monitoring of chronic hepatitis C viral (HCV) infection. Hepatitis C virus-infected African Americans (AAs) have been reported to have lower ALT levels. In this retrospective, cross-sectional, multicenter study, host and virological factors possibly associated with ALT levels were analyzed by multivariate regression analyses among HIV/HCV-coinfected patients. Of the 289 patients included, 142 were African Americans and 144 Caucasians...
January 2010: Journal of the International Association of Physicians in AIDS Care: JIAPAC
https://www.readbyqxmd.com/read/19632954/longer-duration-of-hbv-active-antiretroviral-therapy-is-linked-to-favorable-virological-outcome-in-hiv-hbv-co-infected-patients
#19
Tsan Lee, Marina Núñez
BACKGROUND: HBV-HIV co-infection is associated with increased liver-related morbidity and mortality. Herein we analyzed HBV-related virologic and clinical outcomes in HBV-HIV patients in the HAART era. METHODS: HBsAg positive HIV-infected patients followed at a US academic center between 1990 and 2008 were assessed in a retrospective and longitudinal study. Factors associated with HBsAg and/or HBeAg clearance and with advanced liver disease were evaluated using logistic regression...
May 2009: HIV Clinical Trials
https://www.readbyqxmd.com/read/19372527/characteristics-and-behaviors-associated-with-hiv-infection-among-inmates-in-the-north-carolina-prison-system
#20
David L Rosen, Victor J Schoenbach, David A Wohl, Becky L White, Paul W Stewart, Carol E Golin
OBJECTIVES: We identified factors associated with testing HIV positive in a prison system performing voluntary HIV testing on inmates and estimated the number of undetected HIV cases to evaluate the efficacy of risk-factor-based HIV testing. METHODS: We used logistic regression to estimate associations between HIV serostatus and HIV risk behaviors, mental health, coinfection status, and sociodemographic characteristics for prisoners entering the North Carolina Department of Correction from January 2004 through May 2006...
June 2009: American Journal of Public Health
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