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https://www.readbyqxmd.com/read/28920552/clinical-correlation-of-the-area-of-inferior-vena-cava-iliac-and-femoral-veins-for-stent-use
#1
Afsha Aurshina, Arkady Ganelin, Anil Hingorani, Sheila Blumberg, Yuriy Ostrozhynskyy, Borislav Kheyson, Enrico Ascher
Objective The purpose of the study is to evaluate normal anatomical areas of infrarenal inferior vena cava, common iliac, external iliac and common femoral veins by intravascular ultrasound with the goal of assisting the development of venous-specific stents in the treatment of iliac vein stenosis. Method From February 2012 to December 2013, 656 office-based venograms were performed in our facility. Among them, 576 were stented and 80 were not. The measurements of veins were done intraoperatively using an intravascular ultrasound catheter to record areas of the inferior vena cava, proximal, middle and distal segments of common iliac vein, external iliac vein and common femoral vein...
January 1, 2017: Vascular
https://www.readbyqxmd.com/read/28917753/nuclear-forensics-investigation-of-morphological-signatures-in-the-thermal-decomposition-of-uranyl-peroxide
#2
Ian J Schwerdt, Adam Olsen, Robert Lusk, Sean Heffernan, Michael Klosterman, Bryce Collins, Sean Martinson, Trenton Kirkham, Luther W McDonald
The analytical techniques typically utilized in a nuclear forensic investigation often provide limited information regarding the process history and production conditions of interdicted nuclear material. In this study, scanning electron microscopy (SEM) analysis of the surface morphology of amorphous-UO3 samples calcined at 250, 300, 350, 400, and 450°C from uranyl peroxide was performed to determine if the morphology was indicative of the synthesis route and thermal history for the samples. Thermogravimetic analysis-mass spectrometry (TGA-MS) and differential scanning calorimetry (DSC) were used to correlate transitions in the calcined material to morphological transformations...
January 1, 2018: Talanta
https://www.readbyqxmd.com/read/28917675/regional-variation-in-technetium-pyrophosphate-uptake-in-transthyretin-cardiac-amyloidosis-and-impact-on%C3%A2-mortality
#3
Brett W Sperry, Michael N Vranian, Albree Tower-Rader, Rory Hachamovitch, Mazen Hanna, Richard Brunken, Dermot Phelan, Manuel D Cerqueira, Wael A Jaber
OBJECTIVES: This study sought to investigate the regional uptake of technetium 99m-pyrophosphate (TcPYP) in transthyretin cardiac amyloidosis (ATTR) and its association with mortality. BACKGROUND: TcPYP nuclear scintigraphy is a diagnostic and prognostic tool in ATTR. Echocardiography has identified a pattern of regional variation in longitudinal strain (LS) with a gradient of improved strain from base to apex in ATTR. METHODS: Consecutive patients with ATTR were evaluated who underwent TcPYP nuclear scintigraphy with planar and attenuation corrected single-photon emission computed tomography (SPECT)...
September 9, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28917553/absence-of-rotational-activity-detected-using-two-dimensional-phase-mapping-in-corresponding-three-dimensional-phase-maps-in-human-persistent-atrial-fibrillation
#4
Bhupesh Pathik, Jonathan M Kalman, Tomos Walters, Pawel Kuklik, Jichao Zhao, Andrew Madry, Prashanthan Sanders, Peter M Kistler, Geoffrey Lee
BACKGROUND: Current phase mapping systems for atrial fibrillation(AF) create two-dimensional(2D) maps. This process may affect the accurate detection of rotors. We developed a three-dimensional(3D) phase mapping technique that utilizes the 3D locations of basket electrodes to project phase onto patient-specific left atrial(LA) 3D surface anatomy. OBJECTIVES: We sought to determine whether rotors detected in 2D phase maps were present at corresponding time segments and anatomical locations on 3D phase maps...
September 13, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28915208/appropriate-use-criteria-for-cardiac-computed-tomography-impact-on-diagnostic-utility
#5
Karan Bami, Manuja Premaratne, Jasmine Lamba, Yeung Yam, Alomgir Hossain, Marissa Keenan, Tony Haddad, Saipriya Anand, Ian G Burwash, Terrence D Ruddy, Girish Dwivedi, Benjamin J W Chow
BACKGROUND: Appropriate Use Criteria (AUC) guidelines for cardiac computed tomography (CCT) were developed to limit testing to reasonable clinical settings. However, significant testing is still done for inappropriate indications. This study investigates the impact of AUC on evaluability of CCT to determine if inappropriate tests result in a greater proportion of nondiagnostic results. METHODS: Investigators reviewed the medical records of 2417 consecutive patients who underwent CCT at the University of Ottawa Heart Institute...
September 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28914994/hessian-based-quantitative-image-analysis-of-host-pathogen-confrontation-assays
#6
Zoltan Cseresnyes, Kaswara Kraibooj, Marc Thilo Figge
Host-fungus interactions have gained a lot of interest in the past few decades, mainly due to an increasing number of fungal infections that are often associated with a high mortality rate in the absence of effective therapies. These interactions can be studied at the genetic level or at the functional level via imaging. Here, we introduce a new image processing method that quantifies the interaction between host cells and fungal invaders, for example, alveolar macrophages and the conidia of Aspergillus fumigatus...
September 15, 2017: Cytometry. Part A: the Journal of the International Society for Analytical Cytology
https://www.readbyqxmd.com/read/28912069/generation-of-a-novel-human-cytomegalovirus-bacterial-artificial-chromosome-tailored-for-transduction-of-exogenous-sequences
#7
William L Close, Amit Bhandari, Marwa Hojeij, Philip E Pellett
The study of herpesviruses, including human cytomegalovirus (HCMV), is complicated by viral genome complexity and inefficient methods for genetic manipulation in tissue culture. Reverse genetics of herpesviruses has been facilitated by propagating their genomes in E. coli as bacterial artificial chromosomes (BACs), which enables complex and precise genetic manipulation using bacterial recombinational systems. Internal capsid volume imposes a strict limit on the length of genome that can be packaged efficiently...
September 11, 2017: Virus Research
https://www.readbyqxmd.com/read/28912043/abnormal-segments-of-right-uncinate-fasciculus-and-left-anterior-thalamic-radiation-in-major-and-bipolar-depression
#8
Feng Deng, Ying Wang, Huiyuan Huang, Meiqi Niu, Shuming Zhong, Ling Zhao, Zhangzhang Qi, Xiaoyan Wu, Yao Sun, Chen Niu, Yuan He, Li Huang, Ruiwang Huang
Differential brain structural abnormalities between bipolar disorder (BD) and major depressive disorder (MDD) may reflect different pathological mechanisms underlying these two brain disorders. However, few studies have directly compared the brain structural properties, especially in white matter (WM) tracts, between BD and MDD. Using automated fiber-tract quantification (AFQ), we utilized diffusion tensor images (DTI) from 67 unmedicated depressed patients, including 31 BD and 36 MDD, and 45 healthy controls (HC) to create fractional anisotropy (FA) tract profiles along 20 major WM tracts...
September 11, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28910873/-differential-expression-and-clinical-significance-of-calretinin-in-total-colonic-aganglionosis
#9
L Q Ke, J Huang, L L Liu, M J Huang, Q Zhang, J C Wang, W Zhang
Objective: To evaluate the differential calretinin immunostaining in different segments of total colonic aganglionosis and its utility in the diagnosis. Methods: Nine specimens including ileum and colon segments were obtained from 9 patients with total colonic aganglionosis (TCA), from 2010 to 2016 year, in Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technology. Another 9 ganglionic specimens including the same segments from patients with non-Hirschsprung disease (non-HD) patients were collected as control...
September 8, 2017: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://www.readbyqxmd.com/read/28910754/a-phase-variable-approach-for-imu-based-locomotion-activity-recognition
#10
Harrison L Bartlett, Michael Goldfarb
OBJECTIVE: This paper describes a gait classification method which utilizes measured motion of the thigh segment provided by an inertial measurement unit (IMU). METHODS: The classification method employs a phase-variable description of gait, and identifies a given activity based on the expected curvature characteristics of that activity over a gait cycle. The classification method was tested in experiments conducted with seven healthy subjects performing three different locomotor activities: level ground walking, stair descent, and stair ascent...
September 8, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28910247/pediatric-ambulatory-care-sensitive-conditions-birth-cohorts-and-the-socio-economic-gradient
#11
Leslie L Roos, Roxana Dragan, Robert J Schroth
OBJECTIVES: This study examines the socio-economic gradient in utilization and the risk factors associated with hospitalization for four pediatric ambulatory care sensitive conditions (dental conditions, asthma, gastroenteritis, and bacterial pneumonia). Dental conditions, where much care is provided by dentists and insurance coverage varies among different population segments, present special issues. METHODS: A population registry, provider registry, physician ambulatory claims, and hospital discharge abstracts from 28 398 children born in 2003-2006 in urban centres in Manitoba, Canada were the main data sources...
September 14, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/28904776/escaping-introns-in-coi-through-cdna-barcoding-of-mushrooms-pleurotus-as-a-test-case
#12
Farhat A Avin, Bhassu Subha, Yee-Shin Tan, Thomas W A Braukmann, Sabaratnam Vikineswary, Paul D N Hebert
DNA barcoding involves the use of one or more short, standardized DNA fragments for the rapid identification of species. A 648-bp segment near the 5' terminus of the mitochondrial cytochrome c oxidase subunit I (COI) gene has been adopted as the universal DNA barcode for members of the animal kingdom, but its utility in mushrooms is complicated by the frequent occurrence of large introns. As a consequence, ITS has been adopted as the standard DNA barcode marker for mushrooms despite several shortcomings. This study employed newly designed primers coupled with cDNA analysis to examine COI sequence diversity in six species of Pleurotus and compared these results with those for ITS...
September 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28900183/a-brain-derived-neurotrophic-factor-mimetic-is-sufficient-to-restore-cone-photoreceptor-visual-function-in-an-inherited-blindness-model
#13
Conor Daly, Lisa Shine, Theresa Heffernan, Sudhakar Deeti, Alison L Reynolds, John J O'Connor, Eugène T Dillon, David J Duffy, Walter Kolch, Gerard Cagney, Breandán N Kennedy
Controversially, histone deacetylase inhibitors (HDACi) are in clinical trial for the treatment of inherited retinal degeneration. Utilizing the zebrafish dye (ucd6) model, we determined if treatment with HDACi can rescue cone photoreceptor-mediated visual function. dye exhibit defective visual behaviour and retinal morphology including ciliary marginal zone (CMZ) cell death and decreased photoreceptor outer segment (OS) length, as well as gross morphological defects including hypopigmentation and pericardial oedema...
September 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28894687/the-pedicles-are-not-the-densest-regions-of-the-lumbar-vertebrae-implications-for-bone-quality-assessment-and-surgical-treatment-strategy
#14
Eric A Hohn, Bryant Chu, Audrey Martin, Elizabeth Yu, Connor Telles, Jeremi Leasure, Tennyson L Lynch, Dimitriy Kondrashov
STUDY DESIGN: Cadaver study. OBJECTIVE: To determine the bone density of lumbar vertebral anatomic subregions. Bone mineral density (BMD) is a major factor in osseous fixation construct strength. The standard region for implant fixation of the spine is the pedicle; however, other regions may be more viable options with higher bone quality. METHODS: Using computed tomography images, the spine was digitally isolated by applying a filter for adult bone...
September 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28892516/heterogeneity-and-nonlinearity-in-consumers-preferences-an-application-to-the-olive-oil-shopping-behavior-in-chile
#15
Rodrigo Alejandro Romo-Muñoz, Juan Hernán Cabas-Monje, Héctor Manuel Garrido-Henrríquez, José María Gil
In relatively unknown products, consumers use prices as a quality reference. Under such circumstances, the utility function can be non-negative for a specific price range and generate an inverted U-shaped function. The extra virgin olive oil market in Chile is a good example. Although domestic production and consumption have increased significantly in the last few years, consumer knowledge of this product is still limited. The objective of this study was to analyze Chilean consumer preferences and willingness to pay for extra virgin olive oil attributes...
2017: PloS One
https://www.readbyqxmd.com/read/28892437/public-health-system-research-in-public-health-emergency-preparedness-in-the-united-states-2009-2015-actionable-knowledge-base
#16
Elena Savoia, Leesa Lin, Dottie Bernard, Noah Klein, Lyndon P James, Stefano Guicciardi
BACKGROUND: In 2008, the Institute of Medicine released a letter report identifying 4 research priority areas for public health emergency preparedness in public health system research: (1) enhancing the usefulness of training, (2) improving timely emergency communications, (3) creating and maintaining sustainable response systems, and (4) generating effectiveness criteria and metrics. OBJECTIVES: To (1) identify and characterize public health system research in public health emergency preparedness produced in the United States from 2009 to 2015, (2) synthesize research findings and assess the level of confidence in these findings, and (3) describe the evolution of knowledge production in public health emergency preparedness system research...
September 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28890062/national-utilization-and-outcomes-of-redo-lower-extremity-bypass-vs-endovascular-intervention-after-previous-failed-bypass-redo-lower-extremity-bypass-superior-to-endovascular-intervention
#17
J Hunter Mehaffey, Alexander Shannon, Robert B Hawkins, Anna Fashandi, Margret C Tracci, Irving L Kron, Gilbert R Upchurch, William P Robinson
BACKGROUND: Redo Lower extremity bypass (LEB) and infrainguinal endovascular intervention (IEI) are options to treat critical limb ischemia after a failed prior lower extremity bypass but the utilization and outcomes of each are poorly described. The purpose of this study was to compare 30-day Major Adverse Limb Events (MALE) and Major Adverse Cardiovascular Events (MACE) after LEB and IEI in patients with a failed prior ipsilateral LEB and determine risk factors for each composite outcome...
September 7, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28889004/quantitative-vascular-neuroimaging-of-the-rat-brain-using-superparamagnetic-nanoparticles-new-insights-on-vascular-organization-and-brain-function
#18
Codi A Gharagouzloo, Liam Timms, Ju Qiao, Zihang Fang, Joseph Nneji, Aniket Pandya, Praveen Kulkarni, Anne L van de Ven, Craig Ferris, Srinivas Sridhar
A method called Quantitative Ultra-Short Time-to-Echo Contrast Enhanced (QUTE-CE) Magnetic Resonance Imaging (MRI) which utilizes superparamagnetic iron oxide nanoparticles (SPIONs) as a contrast agent to yield positive contrast angiograms with high clarity and definition is applied to the whole live rat brain. QUTE-CE MRI intensity data are particularly well suited for measuring quantitative cerebral blood volume (qCBV). A global map of qCBV in the awake resting-state with unprecedented detail was created via application of a 3D MRI rat brain atlas with 173 segmented and annotated brain areas...
September 6, 2017: NeuroImage
https://www.readbyqxmd.com/read/28883648/the-utility-of-mtdna-and-rdna-for-barcoding-and-phylogeny-of-plant-parasitic-nematodes-from-longidoridae-nematoda-enoplea
#19
J E Palomares-Rius, C Cantalapiedra-Navarrete, A Archidona-Yuste, S A Subbotin, P Castillo
The traditional identification of plant-parasitic nematode species by morphology and morphometric studies is very difficult because of high morphological variability that can lead to considerable overlap of many characteristics and their ambiguous interpretation. For this reason, it is essential to implement approaches to ensure accurate species identification. DNA barcoding aids in identification and advances species discovery. This study sought to unravel the use of the mitochondrial marker cytochrome c oxidase subunit 1 (coxI) as barcode for Longidoridae species identification, and as a phylogenetic marker...
September 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28881048/a-novel-technique-for-biobanking-of-large-sections-of-radical-prostatectomy-specimens
#20
Claes Lindh, Brett Delahunt, Hemamali Samaratunga, John Yaxley, Jóna Gudjónsdóttir, Mark Clements, Johan Lindberg, Lars Egevad
AIMS: Harvesting of unfixed tissue from radical prostatectomy specimens for research purposes is challenging. Many prostate cancers cannot be identified at gross inspection and this tumour is notoriously multifocal and heterogeneous. We aimed to develop a technique to allow detailed topographic analysis and the sampling of sufficient amount of tumour without jeopardizing clinical reporting. METHODS AND RESULTS: A custom-made double-bladed knife was utilized for cutting a 4 mm thick horizontal section of the prostate...
September 7, 2017: Histopathology
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