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https://www.readbyqxmd.com/read/28528295/a-machine-learning-graph-based-approach-for-3d-segmentation-of-bruch-s-membrane-opening-from-glaucomatous-sd-oct-volumes
#1
Mohammad Saleh Miri, Michael D Abràmoff, Young H Kwon, Milan Sonka, Mona K Garvin
Bruch's membrane opening-minimum rim width (BMO-MRW) is a recently proposed structural parameter which estimates the remaining nerve fiber bundles in the retina and is superior to other conventional structural parameters for diagnosing glaucoma. Measuring this structural parameter requires identification of BMO locations within spectral domain-optical coherence tomography (SD-OCT) volumes. While most automated approaches for segmentation of the BMO either segment the 2D projection of BMO points or identify BMO points in individual B-scans, in this work, we propose a machine-learning graph-based approach for true 3D segmentation of BMO from glaucomatous SD-OCT volumes...
May 6, 2017: Medical Image Analysis
https://www.readbyqxmd.com/read/28527713/stability-or-instability-in-avoidant-personality-disorder-mode-fluctuations-within-schema-therapy-sessions
#2
Ofer Peled, Eran Bar-Kalifa, Eshkol Rafaeli
BACKGROUND AND OBJECTIVES: Avoidant personality disorder (APD) is among the most prevalent personality disorders, but has received relatively little empirical attention. This study aims to characterize the frequency, intensity, and fluctuation patterns seen in the modes (self-states) of APD clients over the course of schema therapy (ST), a psychotherapy approach developed especially for personality disorders. METHOD: The newly-developed client mode rating scale (CMRS) was used to code every 5-min segment (n = 645) of 60 ST sessions...
May 6, 2017: Journal of Behavior Therapy and Experimental Psychiatry
https://www.readbyqxmd.com/read/28526641/elimination-of-subsidence-with-26mm-wide-cages-in-extreme-lateral-interbody-fusion
#3
Gernot Lang, Rodrigo Navarro-Ramirez, Lena Gandevia, Ibrahim Hussain, Jonathan Nakhla, Micaella Zubkov, Roger Härtl
BACKGROUND: Extreme lateral interbody fusion (ELIF) has gained popularity as minimally invasive technique for indirect decompression. However, graft subsidence potentially threatens the long-term success of ELIF. The aim of the study was to evaluate whether 26mm wide cages can eliminate subsidence and subsequent loss of decompression in ELIF. METHODS: Patients undergoing ELIF surgery using a 26mm wide cage were analyzed retrospectively. Patient demographics and peri-operative data for radiographic and clinical outcomes were recorded...
May 16, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28525474/anatomy-of-lamina-in-the-subaxial-cervical-spine-with-the-special-reference-to-translaminar-screws-ct-and-cadaveric-analysis-with-screw-trajectory-simulation
#4
Woojin Cho, Jason T Le, Adam L Shimer, Brian C Werner, John A Glaser, Francis H Shen
STUDY DESIGN: A cadaveric study. SUMMARY OF BACKGROUND DATA: Translaminar screws were initially developed for C2 fixation. Since then, their usage has expanded to include the subaxial cervical spine, and thoracic and lumbar spine. To the best of our knowledge, special anatomy for inserting translaminar screws in the subaxial cervical spine has not been studied. OBJECTIVE: To report the special anatomy for inserting translaminar screws in the subaxial cervical spine...
June 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28523472/assessment-of-coronary-artery-by-prospective-ecg-triggered-256-multi-slice-ct-on-children-with-congenital-heart-disease
#5
Li-Ping Yao, Li Zhang, Hui-Ming Li, Ming Ding, Ling-Wei Yu, Xin Yang, Xiao-Ming Li, Kun Sun
This study aims to investigate the imaging quality and radiation dose of prospective ECG-triggered 256 multi-slice computer tomography (MSCT) in accessing the coronary artery (CA) in children. Coronary arteries of 149 children were evaluated using prospective ECG-triggered 256 MSCT with the same system settings. A four-point scoring system was applied to study the capability of MSCT in detecting CA in these patients. Signal, noise and contrast-to-noise ratios (CNR) were analyzed to investigate the association of image quality with age...
May 18, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28516302/the-minimally-acceptable-classification-criterion-for-surgical-skill-intent-vectors-and-separability-of-raw-motion-data
#6
Rodney L Dockter, Thomas S Lendvay, Robert M Sweet, Timothy M Kowalewski
PURPOSE: Minimally invasive surgery requires objective methods for skill evaluation and training. This work presents the minimally acceptable classification (MAC) criterion for computational surgery: Given an obvious novice and an obvious expert, a surgical skill evaluation classifier must yield 100% accuracy. We propose that a rigorous motion analysis algorithm must meet this minimal benchmark in order to justify its cost and use. METHODS: We use this benchmark to investigate two concepts: First, how separable is raw, multidimensional dry laboratory laparoscopic motion data between obvious novices and obvious experts? We utilized information theoretic techniques to analytically address this...
May 18, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/28516047/prospective-cardiac-motion-self-gating
#7
Fei Han, Stanislas Rapacchi, Peng Hu
BACKGROUND: To develop a prospective cardiac motion self-gating method that provides robust and accurate cardiac triggers in real time. METHODS: The proposed self-gating method consists of an "imaging mode" that acquires the k-space segments and a "self-gating mode" that captures the cardiac motion by repeatedly sampling the k-space centerline. A training based principal component analysis algorithm is utilized to process the self-gating data where the projection onto the first principal component was used as the self-gating signal...
April 2017: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/28515354/clinical-application-and-outcomes-of-sentinel-node-navigation-surgery-in-patients-with-early-gastric-cancer
#8
Takaaki Arigami, Yoshikazu Uenosono, Shigehiro Yanagita, Keishi Okubo, Takashi Kijima, Daisuke Matsushita, Masahiko Amatatsu, Takahiko Hagihara, Naoto Haraguchi, Yuko Mataki, Katsuhiko Ehi, Sumiya Ishigami, Shoji Natsugoe
Sentinel node navigation surgery (SNNS) has been recognized as a minimally invasive tool for individualized lymphadenectomy in patients with early gastric cancer (EGC). The aim of this study was to compare clinicopathological factors, adverse events, and clinical outcomes between sentinel node mapping (SNM) and SN dissection (SND) groups and assess the clinical utility of SNNS in patients with EGC. The clinical data of 157 patients with EGC, diagnosed as clinical T1N0M0 with tumors ≤ 40 mm, undergoing SNNS between March 2004 and April 2016 were retrospectively reviewed...
May 3, 2017: Oncotarget
https://www.readbyqxmd.com/read/28513892/assessment-of-nonarteritic-anterior-ischemic-optic-neuropathy-with-intravoxel-incoherent-motion-diffusion-weighted-imaging-using-readout-segmented-echo-planar-imaging-parallel-imaging-and-2d-navigator-based-reacquisition
#9
Ping Lu, Yan Sha, Hailin Wan, Feng Wang, Guohong Tan, Wenlin Tang
PURPOSE: To determine the feasibility of intravoxel incoherent motion (IVIM) for characterizing perfusion properties and its potential diagnostic utility for nonarteritic anterior ischemic optic neuropathy (NAION). IVIM diffusion-weighted imaging is a promising technique that can measure perfusion and diffusion characteristics simultaneously in a noninvasive manner. MATERIALS AND METHODS: Orbital IVIM in a 3.0T scanner was performed on 33 patients with NAION and 15 controls using readout-segmented echo-planar imaging, parallel imaging, and 2D navigator-based reacquisition (RESOLVE-IVIM)...
May 17, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28513858/an-adaptive-fuzzy-c-means-method-utilizing-neighboring-information-for-breast-tumor-segmentation-in-ultrasound-images
#10
Yuan Feng, Fenglin Dong, Xiaolong Xia, Chun-Hong Hu, Qianmin Fan, Yanle Hu, Mingyuan Gao, Sasa Mutic
PURPOSE: Ultrasound (US) imaging has been widely used in breast tumor diagnosis and treatment intervention. Automatic delineation of the tumor is a crucial first step, especially for the computer-aided diagnosis (CAD) and US-guided breast procedure. However, the intrinsic properties of US images such as low contrast and blurry boundaries pose challenges to the automatic segmentation of the breast tumor. Therefore, the purpose of this study is to propose a segmentation algorithm that can contour the breast tumor in US images...
May 17, 2017: Medical Physics
https://www.readbyqxmd.com/read/28512582/factors-affecting-utilization-of-voluntary-hiv-counseling-and-testing-services-among-teachers-in-awi-zone-northwest-ethiopia
#11
Woudneh Gereme Desta, Mulusew Alemneh Sinishaw, Kelemu Dessie Bizuneh
HIV/AIDS affects the basic educational sector which is the most productive segment of the population and vital to the creation of human capital. The loss of skilled and experienced teachers due to the problem is increasingly compromising the provision of quality education in most African countries. The study was proposed to determine the magnitude of VCT utilization and assess contributing factors that affect VCT service utilization among secondary school teachers in Awi Zone. A cross-sectional study design was conducted among 588 participants in 2014...
2017: AIDS Research and Treatment
https://www.readbyqxmd.com/read/28506470/coronary-ct-angiography-in-the-emergency-department-utilizing-second-and-third-generation-dual-source-ct
#12
Nandini M Meyersohn, Balint Szilveszter, Pedro V Staziaki, Jan-Erik Scholtz, Richard A P Takx, Udo Hoffmann, Brian B Ghoshhajra
BACKGROUND: Coronary computed tomography angiography (coronary CTA) allows efficient triage of low to intermediate risk patients with suspected acute coronary syndrome (ACS) in the emergency department (ED). Techniques for coronary CTA acquisition in the ED continue to evolve with the establishment of standardized scan protocols and the introduction of newer generations of CT hardware. OBJECTIVES: To evaluate qualitative and quantitative image quality and radiation dose exposure of coronary CTA acquired on 2nd versus 3rd generation dual source CT (DSCT) scanners using a standardized institutional scan protocol designed for the ED...
March 22, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28505309/the-herpes-viral-transcription-factor-icp4-forms-a-novel-dna-recognition-complex
#13
Richard B Tunnicliffe, Michael P Lockhart-Cairns, Colin Levy, A Paul Mould, Thomas A Jowitt, Hilary Sito, Clair Baldock, Rozanne M Sandri-Goldin, Alexander P Golovanov
The transcription factor ICP4 from herpes simplex virus has a central role in regulating the gene expression cascade which controls viral infection. Here we present the crystal structure of the functionally essential ICP4 DNA binding domain in complex with a segment from its own promoter, revealing a novel homo-dimeric fold. We also studied the complex in solution by small angle X-Ray scattering, nuclear magnetic resonance and surface-plasmon resonance which indicated that, in addition to the globular domain, a flanking intrinsically disordered region also recognizes DNA...
May 13, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28505059/creation-of-an-adult-observation-unit-improving-outcomes
#14
Joy M Plamann, Judith Zedreck-Gonzalez, Laura Fennimore
A growing segment of patients in hospitals are considered outpatients, classified as observation. These patients neither have the severity of illness nor the intensity of service to qualify as inpatients, yet are not well enough to be discharged. Hospitals have created observation units to address the clinical needs of this growing patient type to provide care in the right setting by managing emergency department throughput and utilizing the most efficient staffing resources. This article describes the change processes and improvements in quality, length of stay, and patient satisfaction, which occurred following the implementation of an adult observation unit...
May 12, 2017: Journal of Nursing Care Quality
https://www.readbyqxmd.com/read/28504947/robust-wireless-power-transmission-to-mm-sized-free-floating-distributed-implants
#15
S Abdollah Mirbozorgi, Pyungwoo Yeon, Maysam Ghovanloo
This paper presents an inductive link for wireless power transmission (WPT) to mm-sized free-floating implants (FFIs) distributed in a large three-dimensional space in the neural tissue that is insensitive to the exact location of the receiver (Rx). The proposed structure utilizes a high-Q resonator on the target wirelessly powered plane that encompasses randomly positioned multiple FFIs, all powered by a large external transmitter (Tx). Based on resonant WPT fundamentals, we have devised a detailed method for optimization of the FFIs and explored design strategies and safety concerns, such as coil segmentation and specific absorption rate limits using realistic finite element simulation models in HFSS including head tissue layers, respectively...
May 11, 2017: IEEE Transactions on Biomedical Circuits and Systems
https://www.readbyqxmd.com/read/28503484/prophylactic-dual-catheter-technique-to-prevent-side-branch-snowplowing-complications-during-angioplasty-and-stenting
#16
Leonard Ll Yeo, W M Wu, Y L Chen, C H Yeh, H F Wong
OBJECTIVE: Angioplasty and Stenting of intracranial atherosclerotic lesions have a higher complication rate and a large proportion of this is attributable to side branch arterial occlusion from forceful displacement of the atheroma into the ostia or snowplowing effect. This can result in severe disabilities when it result in small infarcts involving eloquent areas in the posterior circulation or the motor tracts. MATERIALS AND METHODS: We present a series of 6 cases utilizing a new dual catheter technique for maintaining the patency of at-risk vessels during angioplasty and stenting...
March 2017: Journal of Cerebrovascular and Endovascular Neurosurgery
https://www.readbyqxmd.com/read/28502881/multilevel-schwab-grade-ii-osteotomies-for-sagittal-plane-correction-in-the-management-of-adult-spinal-deformity
#17
George M Ghobrial, Nathan H Lebwohl, Barth A Green, Joseph P Gjolaj
BACKGROUND CONTEXT: Prior reports have compared posterior column osteotomies to pedicle subtraction osteotomies in terms of utility for correcting fixed sagittal imbalance in adolescent patients with deformity. No prior reports have described the use of multilevel Smith-Petersen Osteotomies (SPOs) alone for surgical correction in the adult spinal deformity (ASD) population. PURPOSE: To determine the utility of multilevel Smith-Petersen Osteotomies (SPOs) in the management of global sagittal imbalance in adult spinal deformity (ASD) patients...
May 11, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28501628/evolutionary-expansion-and-structural-functionalism-of-the-ancient-family-of-profilin-proteins
#18
Dhananjay K Pandey, Bhupendra Chaudhary
Structure and functional similarities of a recent protein's orthologs with its ancient counterpart are largely determined by the configuration of evolutionary preservation of amino acids. The emergence of genome sequencing databases allowed dissecting the evolutionarily important gene families at a comprehensive and genome-wide scale. The profilin multi-gene family is an ancient, universal, and functionally diverged across kingdoms, which regulates various aspects of cellular development in both prokarya and eukarya, especially cell-wall maintenance through actin sequestering, nucleation and cytokinesis...
May 10, 2017: Gene
https://www.readbyqxmd.com/read/28495542/endothelial-function-is-preserved-in-veins-harvested-by-either-endoscopic-or-surgical-techniques
#19
Adam R Wheeler, Daniel E Kendrick, Matt T Allemang, Andre F Gosling, Ann H Kim, Alfred Hausladen, Vikram S Kashyap
OBJECTIVES: Endoscopic vein harvest for lower extremity arterial bypass grafting has been questioned due to concern for endothelial damage during procurement. We sought to compare Nitric Oxide (NO)-mediated endothelial dependent relaxation (EDR) in vein segments harvested using open surgical (OH) versus endoscopic (EH) techniques. METHODS: Saphenous vein segments were harvested for lower extremity bypass, and a single, minimally handled section of saphenous vein, free of branches, was taken from the end of the graft...
May 8, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28495008/a-fully-automatic-approach-for-multimodal-pet-and-mr-image-segmentation-in-gamma-knife-treatment-planning
#20
Leonardo Rundo, Alessandro Stefano, Carmelo Militello, Giorgio Russo, Maria Gabriella Sabini, Corrado D'Arrigo, Francesco Marletta, Massimo Ippolito, Giancarlo Mauri, Salvatore Vitabile, Maria Carla Gilardi
BACKGROUND AND OBJECTIVES: Nowadays, clinical practice in Gamma Knife treatments is generally based on MRI anatomical information alone. However, the joint use of MRI and PET images can be useful for considering both anatomical and metabolic information about the lesion to be treated. In this paper we present a co-segmentation method to integrate the segmented Biological Target Volume (BTV), using [(11)C]-Methionine-PET (MET-PET) images, and the segmented Gross Target Volume (GTV), on the respective co-registered MR images...
June 2017: Computer Methods and Programs in Biomedicine
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