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Renal failure obesity adolescent

Anthony M Meyers
INTRODUCTION: An often-quoted remark is to present problems as challenges, which invariably end up in the "in-box", eventually to be swept under the carpet. The chronic kidney disease burden in the South African black population poses a challenging crisis requiring immediate intervention even in a country with limited resources. Aims, materials, and methods: The National Kidney Foundation of South Africa (NKFSA) reports on 3 major projects. The schools project is aimed at prevention, early diagnosis, and appropriate management of chronic kidney disease (CKD) on a national basis...
2016: Clinical Nephrology
Verônica Medeiros da Costa, Patricia de Carvalho Padilha, Géssica Castor Fontes de Lima, Aline Alves Ferreira, Jorge Luiz Luescher, Luciana Porto, Wilza Arantes Ferreira Peres
OBJECTIVES: Describe the overweight frequency (overweight and obesity) and identify the factors associated with this in children and adolescents with type 1 diabetes mellitus (T1DM) treated at a University Children's Hospital in Rio de Janeiro. METHODS: This is an analytical cross-sectional study, which included patients diagnosed with T1DM who had complete anthropometric data (weight and height) and excluded those using drugs with effect on weight gain, genetic syndromes, celiac disease, hypothyroidism, renal failure and other chronic diseases, and pregnant women...
2016: Diabetology & Metabolic Syndrome
Carley A Grimes, Dieuwerke P Bolhuis, Feng J He, Caryl A Nowson
BACKGROUND: Overweight and obesity in children and adults is a major public health concern. Emerging evidence suggests dietary sodium intake may be associated with obesity. This systematic review and meta-analysis will aim to (i) assess the relation between dietary sodium intake and measures of adiposity in children and adults and (ii) examine the relation between sodium intake and sugar-sweetened beverage (SSB) consumption, which is a known risk factor for obesity. METHODS/DESIGN: An electronic search will be conducted using Medline Complete, CINAHL, Scopus, Embase and Cochrane central register of controlled trials (CENTRAL)...
January 18, 2016: Systematic Reviews
Anis Belarbia, Safa Nouira, Wissal Sahtout, Yosra Guedri, Abdellatif Achour
To determine the prevalence of metabolic syndrome (MS) in chronic kidney disease (CKD) patients as well as its effects on the progression of CKD, we conducted a prospective, longitudinal study including 180 patients with chronic renal failure followed at the outpatient service of Nephrology at the Saloul's University Hospital of Sousse (Tunisia) over six months. Our study population consisted of 101 men and 79 women. Chronic glomerulonephritis (36.6%) was the most frequent nephropathy. The mean serum creatinine was 249 ± 200 mmol/L and the mean estimated glomerular filtration rate (eGFR) was 55...
September 2015: Saudi Journal of Kidney Diseases and Transplantation
Amanda Price, Joseph Losek, Benjamin Jackson
AIMS: The aim of this study was to describe the demographical and clinical characteristics, diagnostic difficulties, and morbidity and mortality in children with hyperglycaemic hyperosmolar syndrome (HHS). METHODS: Retrospective cross-section descriptive study of children (<18 years of age) at an urban, tertiary, academic Children's Hospital diagnosed with HHS from January 2002 to December 2011. RESULTS: Six patients met inclusion criteria for the diagnosis of HHS...
January 2016: Journal of Paediatrics and Child Health
Sara Tabtabai, Doreen DeFaria Yeh, Ada Stefanescu, Kevin Kennedy, Robert W Yeh, Ami B Bhatt
Patients with single-ventricle (SV) anatomy now live to adulthood. Little is known about the cost of care and outcomes for patients with SV anatomy, especially those who develop heart failure (HF) cared for in adult hospitals in the United States. We analyzed the Nationwide Inpatient Sample from 2000 to 2011 for patients >14 years admitted to adult hospitals with the International Classifications of Diseases, Ninth Revision, codes for SV anatomy. Demographics, outcomes, co-morbidities, and cost were assessed...
September 1, 2015: American Journal of Cardiology
R Kieszek, A Kwiatkowski, K Jędrzejko, P Domagała, M Bieniasz, M Wszoła, J Drozdrowski, A Tomaszek, J Gozdowska, D Zygier, L Pączek, M Durlik, A Chmura
BACKGROUND: An increase in the number of obese patients on transplantation waiting lists can be observed. There are conflicting results regarding the influence of body mass index (BMI) on graft function. METHODS: We performed a single-center, retrospective study of 859 adult patients who received a renal graft from deceased donors. BMI (kg/m(2)) was calculated from patients' height and weight at the time of transplantation. Kidney recipients were subgrouped into 4 groups, according to their BMI: Groups A (<18...
October 2014: Transplantation Proceedings
Salvatore Micali, Alessio Zordani, Riccardo Galli, Eugenio Martorana, Micaela Piccoli, Gianni Cappelli, Giampaolo Bianchi
BACKGROUND: Laparoendoscopic single-site surgery (LESS) has been developed in an attempt to further reduce the morbidity and scarring associated with laparoscopic surgery. In patients in whom there are indications to perform a laparoscopic renal biopsy, LESS surgery is a valid alternative to mini invasive surgery and is becoming more common. We report our experience on 14 renal biopsy procedures performed in a retroperitoneal LESS. METHODS: LESS renal biopsy was performed in 14 patients 18 to 80 years old (mean age 58...
2014: BMC Urology
A A Dégi, E Kis, A Kerti, O Cseprekál, A J Szabó, G S Reusz
BACKGROUND: Cardiovascular mortality rate in patients with end-stage renal disease is 3 magnitudes higher than in the general population; it remains 10-fold higher after successful renal transplantation (Tx). Among others, obesity and hypertension can exert deleterious effects on vascular structure and function after Tx. Successful kidney transplantation may induce excessive weight gain in part because of the effects of steroid treatment. METHODS: The purpose of this study was to evaluate the presence of obesity in Tx children, their obesity-related metabolic disturbances, and to assess their blood pressure and arterial stiffness in relation to obesity...
July 2014: Transplantation Proceedings
Marianne Schmid, Abd-El-Rahman Abd-El-Barr, Giorgio Gandaglia, Akshay Sood, Kola Olugbade, Nedim Ruhotina, Jesse D Sammon, Briony Varda, Steven L Chang, Adam S Kibel, Felix K Chun, Mani Menon, Margit Fisch, Quoc-Dien Trinh
INTRODUCTION: Patients with renal cell carcinoma who were treated with radical nephrectomy (RN) or partial nephrectomy (PN) are at risk of postoperative acute kidney injury (AKI), and in consequence, short- and long-term adverse outcomes. We sought to identify independent predictors of 30-day AKI in patients undergoing RN or PN. MATERIALS AND METHODS: Between 2005 and 2011, patients who underwent RN or PN for renal cell carcinoma within the National Surgical Quality Improvement Program data set were identified...
November 2014: Urologic Oncology
Wenjing Li, Chunxiu Gong, Di Wu, Min Liu
OBJECTIVE: This report describes two adolescent males in China who suffered from type 2 diabetes mellitus (T2DM) and hyperglycemic hyperosmolar syndrome (HHS) complicated by rhabdomyolysis (RM). After sufficient fluid administration, both patients recovered. DESIGN: Case report. RESULTS: These two obese patients suffered from T2DM, DKA and HHS. Because of insufficient fluid administration, these patients became aggravated and suffered from RM...
November 2014: Journal of Pediatric Endocrinology & Metabolism: JPEM
Xavier F Vela, David O Henríquez, Susana M Zelaya, Delmy V Granados, Marcelo X Hernández, Carlos M Orantes
INTRODUCTION: Chronic kidney disease is a global pandemic, affecting the majority of countries in the world. Its prevalence is approximately 10% and it is associated mainly with diabetes and high blood pressure. In El Salvador, it is the leading cause of hospital deaths among men. OBJECTIVE: Determine prevalence of chronic kidney disease and its risk factors in two Salvadoran farming communities. METHODS: From March through September 2012, a descriptive cross-sectional study was conducted in two Salvadoran farming communities: Dimas Rodríguez (El Paisnal municipality) and El Jícaro (San Agustín municipality)...
April 2014: MEDICC Review
Carlos M Orantes, Raúl Herrera, Miguel Almaguer, Elsy G Brizuela, Lilian Núñez, Nelly P Alvarado, E Jackeline Fuentes, Héctor D Bayarre, Juan Carlos Amaya, Denis J Calero, Xavier F Vela, Susana M Zelaya, Delmy V Granados, Patricia Orellana
INTRODUCTION: In El Salvador, chronic kidney disease is a serious and growing public health problem. Chronic renal failure was the first cause of hospital deaths in men and the fifth in women in 2011. OBJECTIVE: Determine prevalence of CKD, CKD risk factors (traditional and nontraditional) and renal damage markers in the adult population of specific rural areas in El Salvador; measure population distribution of renal function; and identify associated risk factors in CKD patients detected...
April 2014: MEDICC Review
Elaheh Malakan Rad, Farahnak Assadi
Although primary chronic hypertension (HTN) is increasingly common in adolescence, secondary forms of HTN are more common among children. Primary HTN is associated with being overweight and/or a positive family history of HTN. Carotid intima-media thickness, a known risk factor for atherosclerosis is frequent in both adults and children with HTN and other associated cardiovascular (CV) risk factors including obesity, dyslipidemia, diabetes and chronic kidney disease. Left ventricular (LV) hypertrophy is also a common finding in children and adolescents with newly diagnosed HTN...
March 2014: International Journal of Preventive Medicine
John S Gill, Elizabeth Hendren, Jianghu Dong, Olwyn Johnston, Jagbir Gill
BACKGROUND AND OBJECTIVES: Obese patients encounter barriers to medical care not encountered by lean patients, and inequities in access to care among obese patients may vary by sex. This study aimed to determine the association of body mass index (BMI) with access to kidney transplantation in men and women. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: In this retrospective analysis of 702,456 incident ESRD patients aged 18-70 years (captured in the US Renal Data System between 1995 and 2007), multivariate time-to-event analyses were used to determine the association of BMI with likelihood of transplantation from any donor source, transplantation from a living donor, and transplantation from a deceased donor, as well the individual steps in obtaining a deceased donor transplant (activation to the waiting list, and transplantation after wait-listing)...
May 2014: Clinical Journal of the American Society of Nephrology: CJASN
Nancy M Rodig, Kelly C McDermott, Michael F Schneider, Hilary M Hotchkiss, Ora Yadin, Mouin G Seikaly, Susan L Furth, Bradley A Warady
BACKGROUND: Growth failure is common among children with chronic kidney disease (CKD). We examined the relationship of growth parameters with glomerular filtration rate (GFR), CKD diagnosis, sex and laboratory results in children with CKD. METHODS: Baseline data from 799 children (median age 11.0 years, median GFR 49.9 mL/min/1.73 m(2)) participating in the Chronic Kidney Disease in Children Study were examined. Growth was quantified by age-sex-specific height, weight, body mass index (BMI-age), and height-age-sex-specific BMI (BMI-height-age) standard deviation scores (SDS)...
October 2014: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
Rishi Pruthi, Heather Maxwell, Anna Casula, Fiona Braddon, Malcolm Lewis, Catherine O'Brien, Jelena Stojanovic, Yincent Tse, Carol Inward, Manish D Sinha
INTRODUCTION: The British Association for Paediatric Nephrology Registry (BAPN) was established to analyse data related to renal replacement therapy (RRT) in children. The registry receives data from the 13 paediatric nephrology centres in the UK. This chapter aims to provide centre specific data so that individual centres can reflect on the contribution that their data makes to the national picture and to determine the extent to which their patient parameters meet nationally agreed audit standards for the management of children with established renal failure (ERF)...
2013: Nephron. Clinical Practice
Saskia Bruderer, Michael Bodmer, Susan S Jick, Christoph R Meier
OBJECTIVE: Use of diuretics has been associated with an increased risk of gout. Data on different types of diuretics are scarce. We undertook this study to investigate the association between use of loop diuretics, thiazide or thiazide-like diuretics, and potassium-sparing agents and the risk of developing incident gout. METHODS: We conducted a retrospective population-based case-control analysis using the General Practice Research Database established in the UK...
January 2014: Arthritis & Rheumatology
Maria Cristina Maggio, Daniela Montaperto, Silvio Maringhini, Ciro Corrado, Eleonora Gucciardino, Giovanni Corsello
INTRODUCTION: Chronic renal failure (CRF) compromises nutrition, growth, puberty, glycometabolic homeostasis, and adipokine secretion (i.e. adiponectin, resistin, and leptin). Adipokines play a role in the clinical outcome, but data in paediatric patients is scant. AIM: To evaluate the link between kidney function, adiponectin, resistin, leptin, hormonal status, nutritional state and late outcome of CRF children. MATERIALS AND METHODS: We studied leptin, adiponectin and resistin levels in 31 CRF patients (19 males, 12 females, aged 12...
June 2014: Journal of Nephrology
Jun Wu, Shengqiang Yu, Vickram Tejwani, Michael Mao, Angela K Muriithi, Chaoyang Ye, Xuezhi Zhao, Hongchen Gu, Changlin Mei, Qi Qian
BACKGROUND: The objective of this study is to investigate the frequency and clinicopathological features of idiopathic nodular glomerulosclerosis (ING) in Chinese patients, on which there has been no previously published information. METHODS: Native kidney biopsies performed at a kidney histopathological center in Shanghai between January 1, 2009 and December 31, 2011 were retrospectively examined and relevant clinical data were reviewed. RESULTS: All kidney biopsy specimens (3,480) were examined...
December 2014: Clinical and Experimental Nephrology
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