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Xingli Wang, Lang Peng, Kaiyu Wang, Jun Wang, Yang He, Erlong Wang, Defang Chen, Ping Ouyang, Yi Geng, Xiaoli Huang
Channel catfish (Ictalurus punctatus) is an important agricultural fish that has been plagued by Stenotrophomonas maltophilia (S. maltophilia) infections in recent years, some of them severe. The outer membrane proteins (OMPs) of S. maltophilia are one of the most immunogenic and highly conserved candidates for vaccine development in aquaculture. The present study investigated OMPs of S. maltophilia as vaccine on immune response and disease resistance against S. maltophilia of channel catfish and investigated the enhancement effect of natural adjuvants Propolis (Pro), FIG polysaccharide (Fcps), Glycyrrhizine (Gly) to OMPs of S...
October 2016: Fish & Shellfish Immunology
Jessica A Young, Christopher Lind, Willem van Steenbrugge
BACKGROUND: Difficulty participating in conversation is commonly experienced by individuals with dementia, secondary to cognitive and language deficits. Frequent communication partners (FCPs), however, report being largely unaware of how to support their conversation partners with dementia during conversation. In particular, taking a turn appropriately may be difficult for either partner due to trouble predicting a partner's behaviour and, hence, difficulty with timing conversational turns appropriately, potentially resulting in overlapping talk...
April 3, 2016: International Journal of Language & Communication Disorders
Ahmad Zaheer Qureshi
There has been a growing demand for rehabilitation services in Pakistan in recent years, likely due to increasing prevalence of disability. Physical Medicine and Rehabilitation (PM&R) is a branch of medicine which deals with the prevention, diagnosis, and treatment of functional impairments resulting from neuro-musculoskeletal disorders. Physiatrists are physicians who specialize in the specialty of PM&R. College of Physicians and Surgeons of Pakistan started FCPS training in PM&R in the late 1990s. There are various training institutes within and outside Pakistan which are accredited for FCPS training in PM&R...
January 2016: JPMA. the Journal of the Pakistan Medical Association
Susann Schaller-Laudel, Daniela Volke, Matthias Redlich, Marcel Kansy, Ralf Hoffmann, Christian Wilhelm, Reimund Goss
The study investigated the influence of the xanthophyll cycle pigments diadinoxanthin (DD) and diatoxanthin (Dt) on the spectroscopic characteristics, structure and protein composition of isolated fucoxanthin chlorophyll protein (FCP) complexes of the pennate diatom Phaeodactylum tricornutum. 77 K fluorescence emission spectra revealed that Dt-containing FCP complexes showed a characteristic long wavelength fluorescence emission at 700 nm at a pH-value of 5 whereas DD-enriched FCPs retained the typical 680 nm fluorescence emission maximum of isolated FCPs...
November 2015: Plant Physiology and Biochemistry: PPB
Ingunn Olafsdottir, Artur Nemeth, Ester Lörinc, Ervin Toth, Daniel Agardh
OBJECTIVES: The clinical presentation of colonic juvenile polyps with abdominal discomfort and occult rectal bleedings make them difficult to recognize. The aim of this study was to report the clinical features of colonic juvenile polyps in children referred to colonoscopy and evaluate fecal calprotectin (FCP) as a screening biomarker for their diagnosis. METHODS: The study included a total of 266 children (range 3.1-19.0 years, median age 15.8 years) investigated with ileocolonoscopy; of whom, 239 (89%) were investigated for inflammatory bowel disease (IBD)...
January 2016: Journal of Pediatric Gastroenterology and Nutrition
Yuyin Zhou, Mo Chen, Fanrong Zhao, Di Mu, Zhaobin Zhang, Jianying Hu
The occurrence of bisphenol A (BPA), nonylphenol (NP), and their six chlorinated byproducts were investigated in 74 food contacting papers (FCPs) from China, the U.S.A., Japan, and Europe using a sensitive dansylation LC-MS/MS method. BPA (<LOQ-83 ng/g) and NP (<LOQ-5.4 ng/g) were widely detected in FCPs, while the six chlorinated byproducts were detected in less than half of the samples. The concentrations of chlorinated BPAs and chlorinated NPs in FCPs were significantly correlated with the concentrations of BPA and NP, respectively, and their concentrations mainly depended on bleaching processes in paper production...
June 16, 2015: Environmental Science & Technology
Barthélémy Tosello, Lionel Dany, Pierre Bétrémieux, Pierre Le Coz, Pascal Auquier, Catherine Gire, Marie-Ange Einaudi
BACKGROUND: When an incurable fetal condition is detected, some women (or couples) would rather choose to continue with the pregnancy than opt for termination of pregnancy for medical reasons, which, in France, can be performed until full term. Such situations are frequently occurring and sometimes leading to the implementation of neonatal palliative care. The objectives of this study were to evaluate the practices of perinatal care french professionals in this context; to identify the potential obstacles that might interfere with the provision of an appropriate neonatal palliative care; and, from an opposite perspective, to determine the criteria that led, in some cases, to offer this type of care for prenatally diagnosed lethal abnormality...
2015: PloS One
Alexander Sheng, John Eicken, Cheryl Lynn Horton, Eric Nadel, James Takayesu
BACKGROUND: Follow-up case presentation (FCP), a staple of emergency medicine residency conference curricula nationwide, has traditionally been delivered using PowerPoint(TM) (PP). The sole use of the PP lecture format may limit audience participation. In light of existing literature supporting chalkboard and morning report formats, we changed FCP to an interactive chalkboard format with limited PP slides. We hypothesised that this change will enhance the perceived educational impact of FCP on learners...
August 2015: Clinical Teacher
Zhen Wu
Traditionally, people like to take dried finger citron fruits (FC) as adjuvant herbal medicines to treat a diversity of chronic diseases like asthma, hypertension and respiratory tract infections. Many healing properties are attributed to FC polysaccharides (FCPs), one of the main active ingredients of FC. Three drying methods, freeze drying (FDM), hot air drying (HDM) and vacuum drying methods (VDM) were comparatively studied on the physicochemical and antioxidant properties of FCPs. The results showed these FCPs were similar in UV and FT-IR spectrum...
May 2015: International Journal of Biological Macromolecules
Anna Czubatka, Joanna Sarnik, Del Lucent, Janusz Blasiak, Zbigniew J Witczak, Tomasz Poplawski
1,5-Anhydro-6-deoxy-methane-sulfamido-D-glucitol (FCP5) is a functionalized carbohydrate containing functional groups that render it potentially therapeutically useful. According to our concept of 'functional carb-pharmacophores' (FCPs) incorporation of the methanesulfonamido pharmacophore to 1,5 glucitol could create a therapeutically useful compound. Our previous studies revealed that FCP5 was cytotoxic to cancer cells. Therefore, in this work we assessed the cytotoxic mechanisms of FCP5 in four cancer cell lines - HeLa, LoVo, A549 and MCF-7, with particular focus on DNA damage and repair...
February 5, 2015: Chemico-biological Interactions
Chan Jin Jeong, Arup Kumer Roy, Sung Han Kim, Jung-Eun Lee, Ji Hoon Jeong, Insik In, Sung Young Park
Water soluble fluorescent carbon nanoparticles (FCP) obtained from a single natural source, mango fruit, were developed as unique materials for non-toxic bio-imaging with different colors and particle sizes. The prepared FCPs showed blue (FCP-B), green (FCP-G) and yellow (FCP-Y) fluorescence, derived by the controlled carbonization method. The FCPs demonstrated hydrodynamic diameters of 5-15 nm, holding great promise for clinical applications. The biocompatible FCPs demonstrated great potential in biological fields through the results of in vitro imaging and in vivo biodistribution...
December 21, 2014: Nanoscale
Saeid Sadeh, Hridaynath Bhattacharjee, Elaheh Khozeimeh Sarbisheh, J Wilson Quail, Jens Müller
A series of new boron-bridged [1]ferrocenophanes ([1]FCPs) was prepared by salt-metathesis reactions between enantiomerically pure dilithioferrocenes and amino(dichloro)boranes (Et2 NBCl2 , iPr2 NBCl2 , or tBu(Me3 Si)NBCl2 ). The dilithioferrocenes were prepared in situ by lithium-bromine exchange from the respective planar-chiral dibromides (Sp ,Sp )-[1-Br-2-(HR2 C)H3 C5 ]2 Fe (R=Me or Et). In most of the cases, mixtures of the targeted [1]FCPs 4 and the unwanted 1,1'-bis(boryl)ferrocenes 5 were formed. The product ratio depends on the bulkiness of the amino group, the speed of addition of the amino(dichloro)borane, the alkyl group on Cp rings, and in particular on the reaction temperature...
December 1, 2014: Chemistry: a European Journal
Chong Guan Ng, Soo Cheng Chin, Anne Hway Ann Yee, Huai Seng Loh, Ahmad Hatim Sulaiman, Wong Sherianne Sook Kuan, Mohamed Hussain Habil
BACKGROUND: The Snaith-Hamilton Pleasure Scale (SHAPS) is a self-assessment scale designed to evaluate anhedonia in various psychiatric disorders. In order to facilitate its use in Malaysian settings, our current study aimed to examine the validity of a Malay-translated version of the SHAPS (SHAPS-M). METHODS: In this cross-sectional study, a total of 44 depressed patients and 82 healthy subjects were recruited from a university out-patient clinic. All participants were given both the Malay and English versions of the SHAPS, Fawcett-Clark Pleasure Scale (FCPS), General Health Questionnaire 12 (GHQ-12), and the Beck Depression Inventory (BDI) to assess their hedonic state, general mental health condition and levels of depression...
May 2014: Malaysian Journal of Medical Sciences: MJMS
Jie Tian, Yue Zhang, Xiaomin Yang, Ke Rui, Xinyi Tang, Jie Ma, Jianguo Chen, Huaxi Xu, Liwei Lu, Shengjun Wang
Various polysaccharides purified from plants are considered to be biological response modifiers and have been shown to enhance immune responses. Ficus carica L. is a Chinese traditional plant and has been widely used in Asian countries for its anti-tumor properties. Ficus carica polysaccharides (FCPS), one of the most essential and effective components in Ficus carica L., have been considered to be a beneficial immunomodulator and may be used in immunotherapy. However, the immunologic mechanism of FCPS is still unclear...
2014: International Journal of Molecular Sciences
Bidraha Bagh, Saeid Sadeh, Jennifer C Green, Jens Müller
Indium-bridged [1]ferrocenophanes ([1]FCPs) and [1.1]ferrocenophanes ([1.1]FCPs) were synthesized from dilithioferrocene species and indium dichlorides. The reaction of Li2fc⋅tmeda (fc = (H4C5)2Fe) and (Mamx)InCl2 (Mamx = 6-(Me2NCH2)-2,4-tBu2C6H2) gave a mixture of the [1]FCP (Mamx)Infc (4(1)), the [1.1]FCP [(Mamx)Infc]2 (4(2)), and oligomers [(Mamx)Infc]n (4(n)). In a similar reaction, employing the enantiomerically pure, planar-chiral (Sp,Sp)-1,1'-dibromo-2,2'-diisopropylferrocene (1) as a precursor for the dilithioferrocene derivative Li2fc(iPr2), equipped with two iPr groups in the α position, gave the inda[1]ferrocenophane 5(1) [(Mamx)Infc(iPr2)] selectively...
February 17, 2014: Chemistry: a European Journal
Md Wahadoszamen, Artur Ghazaryan, Hande E Cingil, Anjue Mane Ara, Claudia Büchel, Rienk van Grondelle, Rudi Berera
Diatoms are characterized by very efficient photoprotective mechanisms where the excess energy is dissipated as heat in the main antenna system constituted by fucoxanthin-chlorophyll (Chl) protein complexes (FCPs). We performed Stark fluorescence spectroscopy on FCPs in their light-harvesting and energy dissipating states. Our results show that two distinct emitting bands are created upon induction of energy dissipation in FCPa and possibly in FCPb. More specifically one band is characterized by broad red shifted emission above 700nm and bears strong similarity with a red shifted band that we detected in the dissipative state of the major light-harvesting complex II (LHCII) of plants [26]...
January 2014: Biochimica et Biophysica Acta
Saeid Sadeh, Gabriele Schatte, Jens Müller
The enantiomerically pure dibromoferrocene 3 [(Sp,Sp )-1,1'-dibromo-2,2'-di(isopropyl)ferrocene], equipped with two iPr groups in α positions, was prepared using known "Ugi amine" chemistry. Species 3 was targeted in order to gain access to new [1]ferrocenophanes ([1]FCPs) to be used as monomers for ring-opening polymerization. The iPr groups on the sandwich unit were introduced to stabilize bridging moieties, as well as to increase solubilities of targeted metallopolymers. The planar chiral dibromide 3 can quantitatively be lithiated at 0°C [2 equiv nBuLi, hexanes/thf (9:1), 30 min]...
September 27, 2013: Chemistry: a European Journal
Marilena Di Valentin, Elena Meneghin, Laura Orian, Antonino Polimeno, Claudia Büchel, Enrico Salvadori, Christopher W M Kay, Donatella Carbonera
Although the major light harvesting complexes of diatoms, called FCPs (fucoxanthin chlorophyll a/c binding proteins), are related to the cab proteins of higher plants, the structures of these light harvesting protein complexes are much less characterized. Here, a structural/functional model for the "core" of FCP, based on the sequence homology with LHCII, in which two fucoxanthins replace the central luteins and act as quenchers of the Chl a triplet states, is proposed. Combining the information obtained by time-resolved EPR spectroscopy on the triplet states populated under illumination, with quantum mechanical calculations, we discuss the chlorophyll triplet quenching in terms of the geometry of the chlorophyll-carotenoid pairs participating to the process...
October 2013: Biochimica et Biophysica Acta
Lavanya Premvardhan, Matthieu Réfrégiers, Claudia Büchel
The (auto)fluorescence from three diatom strains, Cyclotella meneghiniana (Cm), Phaeodactylum tricornutum 1a (Pt1a), and Phaeodactylum UTex (PtUTex), has been imaged in vivo to submicrometer resolution using confocal laser scanning fluorescence (CLSF) microscopy. The diatoms are excited at 473 and 532 nm, energy primarily absorbed by the carotenoid fucoxanthin (Fx) found within the fucoxanthin chlorophyll a/c proteins (FCPs). On the basis of the fluorescence spectra measured in each image voxel, we obtain information about the spatial and energetic distribution of the terminal Chl a emitters, localized in the FCPs and the reaction centers of the PSII protein complexes, and the nature and location of the primary absorbers that are linked to these emitters; 532 nm excites the highly efficient Fx(red) light harvesters, and lesser amounts of Fx(green)s, that are enriched in some FCPs and preferentially transfer energy to PSII, compared to 473 nm, which excites almost equal amounts of all three previously identified sets of Fx--Fx(red), Fx(green) and Fx(blue)--as well as Chl c...
September 26, 2013: Journal of Physical Chemistry. B
Stephen D Brown, Karen Donelan, Yolanda Martins, Sadath A Sayeed, Christine Mitchell, Terry L Buchmiller, Kelly Burmeister, Jeffrey L Ecker
BACKGROUND: To determine (1) whether fetal care paediatric (FCP) and maternal-fetal medicine (MFM) specialists harbour differing attitudes about pregnancy termination for congenital fetal conditions, their perceived responsibilities to pregnant women and fetuses, and the fetus as a patient and (2) whether self-perceived primary responsibilities to fetuses and women and views about the fetus as a patient are associated with attitudes about clinical care. METHODS: Mail survey of 434 MFM and FCP specialists (response rates 60...
February 2014: Journal of Medical Ethics
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