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https://www.readbyqxmd.com/read/29441675/uterine-adenosarcoma-in-japan-clinicopathologic-features-diagnosis-and-management
#1
Keisei Tate, Reiko Watanabe, Hiroshi Yoshida, Hanako Shimizu, Takashi Uehara, Mitsuya Ishikawa, Shun-Ichi Ikeda, Nobuyoshi Hiraoka, Tomoyasu Kato
AIM: Uterine adenosarcoma is a rare malignancy with limited cohort data in Asian countries. This study evaluated the clinicopathologic features of Japanese patients with uterine adenosarcoma and their potential treatment challenges. METHODS: A retrospective chart review was performed at the National Cancer Center Hospital, Japan from 2000 to 2016. A literature search for Japanese cases of uterine adenosarcoma was conducted using PubMed, Japanese Central Review of Medicine, and the Annual of Pathological Autopsy Cases in Japan...
February 14, 2018: Asia-Pacific Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29435756/laparoscopic-distal-pancreatectomy-which-factors-are-related-to-open-conversion-lessons-learned-from-68-consecutive-procedures-in-a-high-volume-pancreatic-center
#2
Riccardo Casadei, Claudio Ricci, Carlo Alberto Pacilio, Carlo Ingaldi, Giovanni Taffurelli, Francesco Minni
BACKGROUND: Laparoscopic distal pancreatectomy represents a difficult surgical procedure with an high conversion rate to open procedure. The factors related to its difficulty and conversion to open distal pancreatectomy were rarely reported. The aim of the present study was to identify which factors are related to conversion from laparoscopic to open distal pancreatectomy. METHODS: A retrospective study of a prospective database of 68 patients who underwent laparoscopic distal pancreatectomy was conducted at a high-volume center by pancreatic surgeons experienced with laparoscopic surgery...
February 12, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29433337/development-of-a-pre-operative-scoring-system-for-predicting-risk-of-post-operative-paediatric-cerebellar-mutism-syndrome
#3
Jo-Fen Liu, Robert A Dineen, Shivaram Avula, Tom Chambers, Manali Dutta, Tim Jaspan, Donald C MacArthur, Simon Howarth, Daniele Soria, Philip Quinlan, Srikrishna Harave, Chan Chang Ong, Conor L Mallucci, Ram Kumar, Barry Pizer, David A Walker
BACKGROUND: Despite previous identification of pre-operative clinical and radiological predictors of post-operative paediatric cerebellar mutism syndrome (CMS), a unifying pre-operative risk stratification model for use during surgical consent is currently lacking. The aim of the project is to develop a simple imaging-based pre-operative risk scoring scheme to stratify patients in terms of post-operative CMS risk. METHODS: Pre-operative radiological features were recorded for a retrospectively assembled cohort of 89 posterior fossa tumour patients from two major UK treatment centers (age 2-23yrs; gender 28 M, 61 F; diagnosis: 38 pilocytic astrocytoma, 32 medulloblastoma, 12 ependymoma, 1 high grade glioma, 1 pilomyxoid astrocytoma, 1 atypical teratoid rhabdoid tumour, 1 hemangioma, 1 neurilemmoma, 2 oligodendroglioma)...
February 12, 2018: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/29432399/cryoballoon-vs-radiofrequency-contact-force-ablation-for-paroxysmal-atrial-fibrillation-a-propensity-score-analysis
#4
Mario Matta, Matteo Anselmino, Federico Ferraris, Marco Scaglione, Fiorenzo Gaita
BACKGROUND: Radiofrequency and cryoballoon pulmonary vein isolation are common approaches for paroxysmal atrial fibrillation treatment, showing similar results in recent multicenter studies, including heterogeneous tools and protocols. The aim of this study is to compare prospectively in a single, high-volume center the outcome of paroxysmal atrial fibrillation ablation performed specifically by second-generation cryoballoon or contact force radiofrequency ablation. METHODS: Consecutive patients scheduled for paroxysmal atrial fibrillation transcatheter ablation have been included and prospectively followed up...
February 9, 2018: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/29432318/helical-blade-or-the-integrated-lag-screws-a-matched-pair-analysis-of-100-patients-with-unstable-trochanteric-fractures
#5
Ashok S Gavaskar, Naveen C Tummala, Parthasarathy Srinivasan, Hitesh Gopalan, Bhupesh Karthik, S Santhosh
OBJECTIVES: To compare the radiological and clinical results with PFNA - II and InterTan in the treatment of unstable trochanteric fractures in the elderly DESIGN:: Retrospective, multi-center, matched pair SETTING:: 3 tertiary level trauma centres PATIENTS:: 100 elderly patients who underwent intramedullary stabilisation with either the PFNA - II or the InterTan for osteoporotic unstable trochanteric fractures. INTERVENTIONS: 50 matched pairs consisting of AO - A2 and A3 fractures were created from a cohort of 290 patients who underwent internal fixation for unstable trochanteric fractures with the PFNA - II or InterTan nails...
February 9, 2018: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/29429125/cyberknife-robotic-radiosurgery-in-the-multimodal-management-of-acromegaly-patients-with-invasive-macroadenoma-a-single-center-s-experience
#6
Elisa Sala, Justin M Moore, Alvaro Amorin, Hector Martinez, Aprotim C Bhowmik, Layton Lamsam, Steven Chang, Scott G Soltys, Laurence Katznelson, Griffith R Harsh
Surgery is the primary treatment for acromegaly. However, surgery may not be curative of some tumors, particularly invasive macroadenomas. Adjuvant radiation, specifically robotic stereotactic radiosurgery (rSRS), may improve the endocrine outcome. We retrospectively reviewed hormonal and radiological data of 22 acromegalic patients with invasive macroadenomas treated with rSRS at Stanford University Medical Center between 2000 and 2016. Prior to treatment, the tumor's median maximal diameter was 19 mm (2...
February 10, 2018: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/29428981/factors-associated-with-clinical-and-radiological-status-on-admission-in-patients-with-aneurysmal-subarachnoid-hemorrhage
#7
Daniel W Zumofen, Michel Roethlisberger, Rita Achermann, Schatlo Bawarjan, Martin N Stienen, Christian Fung, Donato D'Alonzo, Nicolai Maldaner, Andrea Ferrari, Marco V Corniola, Daniel Schoeni, Johannes Goldberg, Daniele Valsecchi, Thomas Robert, Rodolfo Maduri, Martin Seule, Jan-Karl Burkhardt, Serge Marbacher, Philippe Bijlenga, Kristine A Blackham, Heiner C Bucher, Luigi Mariani, Raphael Guzman
Grading scales yield objective measure of the severity of aneurysmal subarachnoid hemorrhage and serve as to guide treatment decisions and for prognostication. The purpose of this cohort study was to determine what factors govern a patient's disease-specific admission scores in a representative Central European cohort. The Swiss Study of Subarachnoid Hemorrhage includes anonymized data from all tertiary referral centers serving subarachnoid hemorrhage patients in Switzerland. The 2009-2014 dataset was used to evaluate the impact of patient and aneurysm characteristics on the patients' status at admission using descriptive and multivariate regression analysis...
February 10, 2018: Neurosurgical Review
https://www.readbyqxmd.com/read/29428738/estimating-the-health-care-costs-associated-with-recurrent-cellulitis-managed-in-the-outpatient-setting
#8
Jessica St John, Lauren Strazzula, Priyanka Vedak, Daniela Kroshinsky
BACKGROUND: Recurrent cellulitis is diagnosed in 22% to 49% of all cellulitis cases, but little is known about the costs associated with these cases. OBJECTIVE: To characterize patients with recurrent cellulitis in the outpatient setting and estimate the associated costs. METHODS: A retrospective chart review was conducted for adult patients who presented to the outpatient facilities at our institution from January 1, 2007, to December 31, 2011, with recurrent cellulitis...
February 7, 2018: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29428316/variability-induced-by-the-mr-imager-in-dynamic-contrast-enhanced-imaging-of-the-prostate
#9
S Brunelle, C Zemmour, F Bratan, F Mège-Lechevallier, A Ruffion, M Colombel, S Crouzet, A Sarran, O Rouvière
PURPOSE: To evaluate the variability induced by the imager in discriminating high-grade (Gleason≥7) prostate cancers (HGC) using dynamic contrast-enhanced MRI. MATERIAL AND METHODS: We retrospectively selected 3T MRIs with temporal resolution<10 seconds and comprising T1 mapping from a prospective radiologic-pathologic database of patients treated by prostatectomy. Ktrans, Kep, Ve and Vp were calculated for each lesion seen on MRI using the Weinmann arterial input function (AIF) and three patient-specific AIFs measured in the right and left iliac arteries in pixels in the center of the lumen (psAIF-ST) or manually selected by two independent readers (psAIF-R1 and psAIF-R2)...
February 7, 2018: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/29424334/reactive-gliosis-mimicking-tumor-recurrence-a-case-series-documenting-mri-abnormalities-and-neuropathological-correlates
#10
Hugh Kearney, Jane Cryan, Alan Beausung, Seamus Looby, Francesca M Brett
The aim of this study is to identify, in our center, all cases of foreign-body reactions to hemostatic agents or other prostheses resulting in a radiological suspicion of tumor recurrence. We interrogated our internal database to identify all such cases and systematically evaluated the MRI brain scans of patients: (i) at the time of initial tumor diagnosis, (ii) postoperatively, (iii) and at the time of suspected tumor recurrence. In addition, we reviewed each patient's operative notes and reviewed the histology of all cases following a second surgical intervention...
February 9, 2018: Clinical Neuropathology
https://www.readbyqxmd.com/read/29423883/prescribing-immunoglobulin-replacement-therapy-for-patients-with-non-classical-and-secondary-antibody-deficiency-an-analysis-of-the-practice-of-clinical-immunologists-in-the-uk-and-republic-of-ireland
#11
John David M Edgar, Alex G Richter, Aarnoud P Huissoon, Dinakantha S Kumararatne, Helen E Baxendale, Claire A Bethune, Tomaz Garcez, Siraj A Misbah, Ricardo U Sorensen
BACKGROUND: Immunologists are increasingly being asked to assess patients with non-classical and secondary antibody deficiency to determine their potential need for immunoglobulin replacement therapy (IGRT). Immunoglobulin is a limited, expensive resource and no clear guidance exists for this broad patient group. The purpose of this survey is to establish what factors influence the decision to commence IGRT in adult patients, when diagnostic criteria for primary antibody deficiency are not fulfilled...
February 8, 2018: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/29420550/spectrum-of-interstitial-lung-diseases-at-a-tertiary-center-in-a-developing-country-a-study-of-803-subjects
#12
Sahajal Dhooria, Ritesh Agarwal, Inderpaul Singh Sehgal, Kuruswamy Thurai Prasad, Mandeep Garg, Amanjit Bal, Ashutosh Nath Aggarwal, Digambar Behera
BACKGROUND: The spectrum of interstitial lung diseases (ILDs) have mainly been reported from the developed countries; data from developing countries is sparse and conflicting. The aim of this study is to describe the distribution of various ILDs from a developing country. METHODS: This is an analysis of prospectively collected clinical, radiological and histological data of consecutive subjects (age >12 years) with ILDs from a single tertiary care medical center...
2018: PloS One
https://www.readbyqxmd.com/read/29419769/ionizing-radiation-measurement-solution-in-a-hospital-environment
#13
Antonio-Javier Garcia-Sanchez, Enrique Angel Garcia Angosto, Pedro Antonio Moreno Riquelme, Alfredo Serna Berna, David Ramos-Amores
Ionizing radiation is one of the main risks affecting healthcare workers and patients worldwide. Special attention has to be paid to medical staff in the vicinity of radiological equipment or patients undergoing radioisotope procedures. To measure radiation values, traditional area meters are strategically placed in hospitals and personal dosimeters are worn by workers. However, important drawbacks inherent to these systems in terms of cost, detection precision, real time data processing, flexibility, and so on, have been detected and carefully detailed...
February 8, 2018: Sensors
https://www.readbyqxmd.com/read/29419474/frequency-diagnosis-treatment-and-outcome-of-gastrointestinal-disease-in-granulomatosis-with-polyangiitis-and-microscopic-polyangiitis
#14
Per Eriksson, Mårten Segelmark, Olof Hallböök
OBJECTIVE: Involvement of the gastrointestinal (GI) tract is a rare complication of granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA). The aim was to describe frequency, diagnosis, treatment, and outcome of GI disease in a large series of patients in a single center. METHODS: A database that includes all patients with GPA and MPA diagnosed since 1997 in a defined area of southeastern Sweden as well as prevalent older cases and tertiary referral patients was screened for patients with GI disease...
February 1, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29418060/ectopic-nephrogenic-rests-in-children-a-series-of-13-cases-in-a-single-institution
#15
Yangyang Ma, Jicui Zheng, Jiayan Feng, Haitao Zhu, Xianmin Xiao, Lian Chen
PURPOSE: Ectopic nephrogenic rests (ENR) are extremely rare, and their diagnosis and treatment have not yet been standardized. Our study aimed to analyze the clinical and pathological features of ENR in children and explore the optimal methods for diagnosis and treatment. METHODS: A retrospective, single-center, case series study of 13 children with ENR was performed. Clinical manifestations, work-up, pathological features, and treatment methods were analyzed, and the postoperative status was evaluated at follow-up...
February 8, 2018: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29417268/retrospective-single-arm-cohort-study-of-patients-with-hepatocellular-adenomas-treated-with-percutaneous-thermal-ablation
#16
Oleg Mironov, Arash Jaberi, Robert Beecroft, John R Kachura
PURPOSE: To assess the safety and efficacy of percutaneous thermal ablation for the treatment of hepatocellular adenomas. MATERIALS AND METHODS: This is an ethics board-approved, single-arm, retrospective, cohort study of patients with pathologically proven hepatocellular adenomas treated with percutaneous thermal ablation at a tertiary referral center from 1999 to 2016. Demographic, procedural, and outcome data were collected and summarized with appropriate measures of central tendency and dispersion...
February 7, 2018: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29415192/chilaiditi-s-syndrome-causing-high-grade-small-bowel-obstruction-requiring-exploratory-laparotomy
#17
Daniel Fiumecaldo, Lauren Buck
Chilaiditi's sign is a radiological finding that occurs when the small or large intestine is positioned superior to the liver in the sub-diaphragmatic space. This is typically an asymptomatic radiological sign, but when symptoms occur, e.g., abdominal pain, nausea, emesis, it is termed Chilaiditi's syndrome. Currently, majority of the cases of Chilaiditi's syndrome, described in the literature, requiring operative intervention are due to large bowel obstruction or colonic volvulus. The following is a single case report of a patient presenting to Keesler Medical Center in Biloxi, Mississippi...
February 5, 2018: Military Medicine
https://www.readbyqxmd.com/read/29408575/supratentorial-cortical-ependymomas-a-retrospective-series-of-13-cases-at-a-single-center
#18
Mengmeng Wang, Rende Zhang, Xueyou Liu, Dongming Li, Peichao Zhao, Yuchao Zuo, Peng Zhang, Junkuan Wang, Hongwei Sun
OBJECTIVE: Cortical ependymomas (CEs), supratentorial ependymoma that selectively involve the cerebral cortex, is relatively rare neoplasm which have not been extensively described. The purpose of our study was to identify the clinical features, radiologic characteristics, and treatment of a series of such tumors. METHODS: Thirteen patients with cortical ependymomas from our hospital were included in this study. Epidemiological characteristics, clinical features, imaging findings, treatment methods and clinical outcomes were reviewed retrospectively...
January 30, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29405934/perinatal-and-infantile-hypophosphatasia-clinical-features-and-treatment
#19
G Baujat, C Michot, K H Le Quan Sang, V Cormier-Daire
Hypophosphatasia (HPP) is a rare hereditary disease characterized by defective skeletal mineralization, and with a broad severity spectrum. The perinatal forms, lethal and non-lethal, are associated with severe neonatal respiratory distress, potential seizures, hypotrophy and marked hypotonia. The diagnosis is rapidly suggested by a combination of typical radiological signs, hypercalcemia, hyperphosphatemia and low alkaline phosphatase (ALP) activity. In the infantile form, the clinical signs appear before the age of six months, but the patients usually have no or very mild signs at birth...
May 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/29404583/differences-in-the-reponses-to-apheresis-therapy-of-patients-with-3-histopathologically-classified-immunopathological-patterns-of-multiple-sclerosis
#20
Lidia Stork, David Ellenberger, Tim Beißbarth, Tim Friede, Claudia F Lucchinetti, Wolfgang Brück, Imke Metz
Importance: Plasma exchange and immunoadsorption are second-line apheresis therapies for patients experiencing multiple sclerosis relapses. Early active multiple sclerosis lesions can be classified into different histopathological patterns of demyelination. Pattern 1 and 2 lesions show T-cell- and macrophage-associated demyelination, and pattern 2 is selectively associated with immunoglobulin and complement deposits, suggesting a humoral immune response. Pattern 3 lesions show signs of oligodendrocyte degeneration...
February 5, 2018: JAMA Neurology
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