keyword
MENU ▼
Read by QxMD icon Read
search

Charlie

keyword
https://www.readbyqxmd.com/read/29147536/a-complementary-pair-of-enantioselective-switchable-organocatalysts
#1
Guillaume De Bo, David A Leigh, Charlie T McTernan, Shoufeng Wang
A pair of enantioselective switchable bifunctional catalysts are shown to promote a range of conjugate addition reactions in up to 95 : 5 e.r. and 95% conversion. Each catalyst can be switched OFF using conditions that switch the other catalyst ON. Catalyst ON : OFF ratios of up to 98 : 2 and 1 : 99 were achieved, with a ratio of reaction rates of up to 16 : 1 between the ON and OFF states, maintained over complete ON-OFF-ON and OFF-ON-OFF cycles. However, simultaneous operation of the catalyst pair in the same reaction vessel, which in principle could allow product handedness to be switched by simple E-Z isomerisation of the catalyst pair, was unsuccessful...
October 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/29143331/implicit-review-instrument-to-evaluate-quality-of-care-delivered-by-physicians-to-children-in-emergency-departments
#2
James P Marcin, Patrick S Romano, Madan Dharmar, James M Chamberlain, Nanette Dudley, Charles G Macias, Lise E Nigrovic, Elizabeth C Powell, Alexander J Rogers, Meridith Sonnett, Leah Tzimenatos, Elizabeth R Alpern, Rebecca Andrews-Dickert, Dominic A Borgialli, Erika Sidney, Charlie Casper, Jonathan Michael Dean, Nathan Kuppermann
OBJECTIVE: To evaluate the consistency, reliability, and validity of an implicit review instrument that measures the quality of care provided to children in the emergency department (ED). DATA SOURCES/STUDY SETTING: Medical records of randomly selected children from 12 EDs in the Pediatric Emergency Care Applied Research Network (PECARN). STUDY DESIGN: Eight pediatric emergency medicine physicians applied the instrument to 620 medical records...
November 16, 2017: Health Services Research
https://www.readbyqxmd.com/read/29141897/effects-of-health-and-social-care-spending-constraints-on-mortality-in-england-a-time-trend-analysis
#3
Johnathan Watkins, Wahyu Wulaningsih, Charlie Da Zhou, Dominic C Marshall, Guia D C Sylianteng, Phyllis G Dela Rosa, Viveka A Miguel, Rosalind Raine, Lawrence P King, Mahiben Maruthappu
OBJECTIVE: Since 2010, England has experienced relative constraints in public expenditure on healthcare (PEH) and social care (PES). We sought to determine whether these constraints have affected mortality rates. METHODS: We collected data on health and social care resources and finances for England from 2001 to 2014. Time trend analyses were conducted to compare the actual mortality rates in 2011-2014 with the counterfactual rates expected based on trends before spending constraints...
November 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/29140122/lymphangioleiomyomatosis-diagnosis-and-management-high-resolution-chest-computed-tomography-transbronchial-lung-biopsy-and-pleural-disease-management-an-official-american-thoracic-society-japanese-respiratory-society-clinical-practice-guideline
#4
Nishant Gupta, Geraldine A Finlay, Robert M Kotloff, Charlie Strange, Kevin C Wilson, Lisa R Young, Angelo M Taveira-DaSilva, Simon R Johnson, Vincent Cottin, Steven A Sahn, Jay H Ryu, Kuniaki Seyama, Yoshikazu Inoue, Gregory P Downey, MeiLan K Han, Thomas V Colby, Kathryn A Wikenheiser-Brokamp, Cristopher A Meyer, Karen Smith, Joel Moss, Francis X McCormack
BACKGROUND: Recommendations regarding key aspects related to the diagnosis and pharmacological treatment of lymphangioleiomyomatosis (LAM) were recently published. We now provide additional recommendations regarding four specific questions related to the diagnosis of LAM and management of pneumothoraces in patients with LAM. METHODS: Systematic reviews were performed and then discussed by a multidisciplinary panel. For each intervention, the panel considered its confidence in the estimated effects, the balance of desirable (i...
November 15, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29138146/five-minutes-with-charlie-auld
#5
Anne Gulland
No abstract text is available yet for this article.
November 14, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29132700/early-operation-in-patients-with-mitral-valve-infective-endocarditis-and-acute-stroke-is-safe
#6
Mehrdad Ghoreishi, Nate Foster, Chetan Pasrija, Aakash Shah, A Claire Watkins, Charlie F Evans, Sam Maghami, Rachael Quinn, Brody Wehman, Bradley S Taylor, Murtaza Y Dawood, Bartley P Griffith, James S Gammie
BACKGROUND: To determine if preoperative embolic stroke is associated with an increased risk of postoperative stroke among patients undergoing early operation for mitral valve (MV) infective endocarditis (IE), we compared outcomes among patients presenting with and without acute stroke. METHODS: From 2003 to 2015, 243 consecutive patients underwent surgery for active MV IE. Patients were categorized into 2 groups: 72% (174 of 243 patients) with no preoperative acute stroke (clinical, radiographic or both) and 28% (69 of 243 patients) with stroke...
November 11, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29132004/how-are-perceptions-associated-with-water-consumption-in-canadian-inuit-a-cross-sectional-survey-in-rigolet-labrador
#7
Carlee J Wright, Jan M Sargeant, Victoria L Edge, James D Ford, Khosrow Farahbakhsh, Inez Shiwak, Charlie Flowers, Allan C Gordon, Sherilee L Harper
Concerns regarding the safety and aesthetic qualities of one's municipal drinking water supply are important factors influencing drinking water perceptions and consumption patterns (i.e. sources used and daily volume of consumption). In northern Canada, Inuit communities face challenges with drinking water quality, and many Inuit have reported concerns regarding the safety of their drinking water. The objectives of this research were to describe perceptions of municipal tap water, examine use of water sources and changes following the installation of a potable water dispensing unit (PWDU) in 2014, and identify factors associated with water consumption in the Inuit community of Rigolet...
November 10, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29125396/therapies-and-mechanisms-of-opioid-withdrawal
#8
Nicole E Burma, Charlie Ht Kwok, Tuan Trang
No abstract text is available yet for this article.
November 10, 2017: Pain Management
https://www.readbyqxmd.com/read/29122078/the-role-of-regulatory-t-cells-in-the-regulation-of-upper-airway-inflammation
#9
Charlie Palmer, Jennifer K Mulligan, Sarah E Smith, Carl Atkinson
Allergic rhinitis (AR) and chronic rhinosinusitis with nasal polyps (CRSwNP) are inflammatory diseases of the upper airway, with a similar immunologic profile, characterized by aberrant and persistent type 2 inflammation. One cell population that has been identified as altered in both disease types is regulatory T cell (Treg). Tregs have the capacity to modulate T-effector function and suppress inflammatory cytokine production in a broad range of cell types. Given the ability of Tregs to control inflammation, the role of Tregs in respiratory diseases has attracted much attention...
November 1, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29120360/elemental-ingredients-in-the-macrophage-cocktail-role-of-zip8-in-host-response-to-mycobacterium-tuberculosis
#10
REVIEW
Charlie J Pyle, Abul K Azad, Audrey C Papp, Wolfgang Sadee, Daren L Knoell, Larry S Schlesinger
Tuberculosis (TB) is a global epidemic caused by the infection of human macrophages with the world's most deadly single bacterial pathogen, Mycobacterium tuberculosis (M.tb). M.tb resides in a phagosomal niche within macrophages, where trace element concentrations impact the immune response, bacterial metal metabolism, and bacterial survival. The manipulation of micronutrients is a critical mechanism of host defense against infection. In particular, the human zinc transporter Zrt-/Irt-like protein 8 (ZIP8), one of 14 ZIP family members, is important in the flux of divalent cations, including zinc, into the cytoplasm of macrophages...
November 9, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29116669/altered-states-of-consciousness-evaluation-of-a-voice-hearing-simulation-during-an-immersive-art-exhibition
#11
Simon Riches, Rich Maskey, Rachel Waddingham, Jonny Benjamin, Patrick Dishman, Charlie Tebrook, Eve Mundy, Phoebe Roberts, Helen L Fisher
AIM: To improve public understanding of the subjective experience of auditory hallucinations and increase empathy towards individuals who hear voices and have other unusual sensory experiences. METHODS: This pilot study developed a new immersive art exhibition, Altered States of Consciousness, which gave members of the public an individualized voice-hearing simulation experience in 2 real-world settings-an art gallery and the London Underground. A total of 150 visitors completed visual analogue scales immediately before and after their experience of the exhibition...
November 8, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/29115881/a-review-of-current-and-developing-fixed-dose-laba-lama-combinations-for-treating-copd
#12
Chitra Lal, Charlie Strange
The current GOLD (Global Initiative for Chronic Obstructive Lung Disease) recommendations suggest using long acting β2 agonists (LABA) and long acting muscarinic antagonists (LAMA) in combination for group B COPD patients with persistent symptoms, group C COPD patients with further exacerbations on LAMA therapy alone and for group D COPD patients with or without combination with inhaled corticosteroids (ICS). Thus, there is a lot of interest in developing LABA/LAMA combinations for maintenance therapy of chronic stable COPD...
November 8, 2017: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/29112647/intrauterine-device-use-and-cervical-cancer-risk-a-systematic-review-and-meta-analysis
#13
Victoria K Cortessis, Malcolm Barrett, Niquelle Brown Wade, Temuulen Enebish, Judith L Perrigo, Jessica Tobin, Charlie Zhong, Jennifer Zink, Vanessa Isiaka, Laila I Muderspach, Melissa Natavio, Roberta McKean-Cowdin
OBJECTIVE: To estimate the association between use of an intrauterine device (IUD) and risk of cervical cancer by subjecting existing data to critical review, quantitative synthesis, and interpretation. DATA SOURCES: We searched PubMed, Web of Science, ClinicalTrials.gov, and catalogs of scientific meetings and abstracts, theses, and dissertations queried from inception through July 2016. METHODS OF STUDY SELECTION: Examination of abstracts from 225 reports identified 34 studies with individual-level measures of use of an IUD and incident cervical cancer...
November 3, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29110710/potential-effectiveness-of-chinese-herbal-medicine-yu-ping-feng-san-for-adult-allergic-rhinitis-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#14
Qiulan Luo, Claire Shuiqing Zhang, Lihong Yang, Anthony Lin Zhang, Xinfeng Guo, Charlie Changli Xue, Chuanjian Lu
BACKGROUND: Chinese herbal medicine formula Yu ping feng san (YPFS) is commonly used for allergic rhinitis (AR). Previous review had summarized the effectiveness and safety of YPFS, however without any subgroup analysis performed to provide detailed evidence for guiding clinical practice. YPFS was recommended for the management of AR by Chinese medicine clinical practice guideline, but the treatment duration of YPFS was also not specified. The aim of this study is to evaluate the effectiveness and safety of YPFS in treating adult AR with the most recent evidence, and attempt to specify the duration of utilisation through subgroup meta-analyses...
November 6, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29110172/when-doctors-and-parents-don-t-agree-the-story-of-charlie-gard
#15
Natasha Hammond-Browning
This discussion follows a series of high profile cases involving a terminally ill child, Charlie Gard. These cases are significant as they trace the complexities that arise when parents and medical teams do not agree as well as addressing the question of whether there is a right to access experimental treatment.
November 6, 2017: Journal of Bioethical Inquiry
https://www.readbyqxmd.com/read/29108506/what-can-we-learn-from-the-case-of-charlie-gard-perspectives-from-an-inter-disciplinary-panel-discussion
#16
Ann Gallagher
No abstract text is available yet for this article.
November 2017: Nursing Ethics
https://www.readbyqxmd.com/read/29101964/catheter-ablation-vs-electrophysiologically-guided-thoracoscopic-surgical-ablation-in-long-standing-persistent-atrial-fibrillation-the-casa-af-study
#17
Shouvik K Haldar, David G Jones, Toufan Bahrami, Anthony De Souza, Sandeep Panikker, Charlie Butcher, Habib Khan, Rashmi Yahdav, Julian Jarman, Lilian Mantziari, Eva Nyktari, Raad Mohiaddin, Wajid Hussain, Vias Markides, Tom Wong
BACKGROUND: Catheter ablation (CA) outcomes for long-standing persistent atrial fibrillation (LSPAF) remain suboptimal. Thoracoscopic surgical ablation (SA) provides an alternative approach in this difficult to treat cohort. OBJECTIVE: To compare electrophysiological (EP) guided thoracoscopic SA with percutaneous CA as the first-line strategy in the treatment of LSPAF. METHODS: Fifty-one patients with de novo symptomatic LSPAF were recruited...
November 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29100042/trends-in-breast-imaging-an-analysis-of-21years-of-formal-scientific-abstracts-at-the-radiological-society-of-north-america
#18
Samantha L Heller, Abbas Charlie, James S Babb, Linda Moy, Yiming Gao
PURPOSE: To capture shifts in breast imaging through 21years of scientific meeting abstracts. MATERIALS AND METHODS: RSNA meeting programs (1995-2015) were searched to identify breast imaging scientific oral abstracts. Abstract year, author gender and degree, country, state, study design, modality, topic, funding and disclosures were recorded. Spearman correlation was performed. RESULTS: There was an increase in %women first authors (rs=0...
October 28, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/29099176/catalytic-water-oxidation-by-a-bio-inspired-nickel-complex-with-a-redox-active-ligand
#19
Dong Wang, Charlie O Bruner
The oxidation of water (H2O) to dioxygen (O2) is important in natural photosynthesis. One of nature's strategies for managing such multi-electron transfer reactions is to employ redox-active metal-organic cofactor arrays. One prototype example is the copper tyrosinate active site found in galactose oxidase. In this work, we have implemented such a strategy to develop a bio-inspired nickel phenolate complex capable of catalyzing the oxidation of H2O to O2 electrochemically at neutral pH with a modest overpotential...
November 3, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/29097153/finding-myod-and-lessons-learned-along-the-way
#20
REVIEW
Andrew B Lassar
In 1987, Robert Davis, Hal Weintraub and I reported the identification of MyoD, a transcription factor that could reprogram fibroblasts into skeletal muscle cells. In this recollection, I both summarize the prior work of Helen Blau, Woody Wright, Peter Jones and Charlie Emerson that inspired my entry into this field, and the subsequent events that led to finding MyoD. Lastly, I highlight some of the principles in developmental biology that have emerged during the past 30 years, which are particularly relevant to skeletal muscle biology...
November 1, 2017: Seminars in Cell & Developmental Biology
keyword
keyword
90178
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"