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https://www.readbyqxmd.com/read/29238271/dual-depression-a-sex-perspective
#1
Adriana Farré, Judit Tirado-Muñoz, Marta Torrens
Mood and substance use disorders (SUDs) are mental conditions that are highly prevalent in the general population. Cooccurrence of major depression and SUD, also known as dual depression, is very common in the field of substance addiction. Sex differences are found in both major depression and SUD. This review, after presenting the state of the art of dual depression as regards prevalence, ethiopathologic mechanisms, and clinical aspects, is focused on dual depression in women. An overview of some potential factors associated with the sex gap in dual depression such as injecting, sexual risk behavior, intimate partner violence, and the reproductive cycle is presented...
December 2017: Addictive Disorders & Their Treatment
https://www.readbyqxmd.com/read/29234834/contributions-of-prolonged-contingent-and-non-contingent-cocaine-exposure-to-escalation-of-cocaine-intake-and-glutamatergic-gene-expression
#2
Kyle L Ploense, Philip Vieira, Lana Bubalo, Gema Olivarria, Amanda E Carr, Karen K Szumlinski, Tod E Kippin
Similar to the pattern observed in people with substance abuse disorders, laboratory animals will exhibit escalation of cocaine intake when the drug is available over prolonged periods of time. Here, we investigated the contribution of behavioral contingency of cocaine administration on escalation of cocaine intake and gene expression in the dorsal medial prefrontal cortex (dmPFC) in adult male rats. Rats were allowed to self-administer intravenous cocaine (0.25 mg/infusion) under either limited cocaine-(1 h/day), prolonged cocaine-(6 h/day), or limited cocaine-(1 h/day) plus yoked cocaine-access (5 h/day); a control group received access to saline (1 h/day)...
December 12, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/29234453/an-association-study-of-taq1a-ankk1-and-c957t-and-%C3%A2-141c-drd2-polymorphisms-in-adults-with-internet-gaming-disorder-a-pilot-study
#3
Soo-Hyun Paik, Mi Ran Choi, Su Min Kwak, Sol Hee Bang, Ji-Won Chun, Jin-Young Kim, Jihye Choi, Hyun Cho, Jo-Eun Jeong, Dai-Jin Kim
Background: Though Internet gaming disorder (IGD) is considered to share similar genetic vulnerability with substance addictions, little has been explored about the role of the genetic variants on IGD. This pilot study was designed to investigate the association of the Taq1A polymorphism of the ankyrin repeat and kinase domain containing 1 (ANKK1) gene and C957T and - 141C of the dopamine D2 receptor (DRD2) with IGD and their role on the personality and temperament traits in IGD among adult population...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29232576/effects-of-oxytocin-on-cortisol-reactivity-and-conflict-resolution-behaviors-among-couples-with-substance-misuse
#4
Julianne C Flanagan, Melanie S Fischer, Paul J Nietert, Sudie E Back, Megan Moran-Santa Maria, Alexandra Snead, Kathleen T Brady
Social stress, particularly in the form of dyadic conflict, is a well-established correlate of substance use disorders (SUD). The neuropeptide oxytocin can enhance prosocial behavior and mitigate addictive behaviors. These effects may be, in part, a result of oxytocin's ability to attenuate hypothalamic-pituitary-adrenal (HPA) axis dysregulation. However, only one study to date has examined the effects of oxytocin on neuroendocrine reactivity or conflict resolution behavior among couples. Participants (N = 33 couples or 66 total participants) were heterosexual couples in which one or both partners endorsed substance misuse...
December 6, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29232248/endocarditis-in-the-setting-of-idu-multidisciplinary-management
#5
Bobby Yanagawa, Anees Bahji, Wiplove Lamba, Darrell H Tan, Asim Cheema, Ishba Syed, Subodh Verma
PURPOSE OF REVIEW: The purpose of this article is to provide a brief overview of the medical and surgical management of infective endocarditis secondary to IDU, with a focus on the underlying substance use disorder. RECENT FINDINGS: Patients with infective endocarditis secondary to IDU are often young with unique comorbidities including mental illness, chronic hepatitis C, HIV infection, which are often compounded by limited social and familial supports. The focus of management has been treatment of endocarditis using IV antibiotics alongside surgery...
December 11, 2017: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/29231765/imaging-corticotropin-releasing-factor-and-nociceptin-in-addiction-and-ptsd-models
#6
Savannah Tollefson, Michael Himes, Rajesh Narendran
Addiction is composed of three phases: intoxication, withdrawal, and craving. Negative reinforcement, strengthening a behaviour by removing an aversive stimulus, has been associated with the withdrawal phase. An imbalance of neurotransmitters within the brain's stress (nociceptin, neuropeptide Y) and anti-stress (CRF, norepinephrine, etc.) system is attributed to negatively reinforced compulsive behaviours associated with relapse. Similarly, post-traumatic stress disorder is characterized by an overactive stress system...
December 12, 2017: International Review of Psychiatry
https://www.readbyqxmd.com/read/29226100/clinical-food-addiction-is-not-associated-with-development-of-metabolic-complications-in-liver-transplant-recipients
#7
Sammy Saab, Cameron Sikavi, Melissa Jimenez, Matthew Viramontes, Ruby Allen, Youssef Challita, Michelle Mai, Negin Esmailzadeh, Jonathan Grotts, Gina Choi, Francisco Durazo, Mohamed El-Kabany, Steven-Huy Han, Elisa Moreno
Background and Aims: Given the increased risk of post-transplant metabolic syndrome (PTMS; defined by hypertension, diabetes mellitus and hyperlipidemia), we aimed to identify the potential role of food addiction in the development of metabolic complications in the post-liver transplant population. Methods: Inclusion criteria included adult liver transplant recipients followed at our institution between June 2016 and November 2016. Participants were administered a demographic survey as well as the Yale Food Assessment Scale 2...
December 28, 2017: Journal of Clinical and Translational Hepatology
https://www.readbyqxmd.com/read/29223953/potential-role-for-acupuncture-in-the-treatment-of-food-addiction-and-obesity
#8
Jason Aaron Chen, Justin Albert Chen, Sanghoon Lee, Gerard Mullin
Addressing the global obesity epidemic requires innovative approaches that are also acceptable to affected individuals. There is growing evidence suggesting that food addiction, one contributor to obesity, bears many similarities to drug and alcohol addiction, presenting a potential role for addiction-focused acupuncture as a novel treatment modality. In this perspective article, we begin by briefly reviewing the evidence linking food and drug/alcohol addiction. We then describe the development of an acupuncture-based protocol for treating opioid addiction in Hong Kong in the 1970s and discuss the evidence base for acupuncture's efficacy in treating a range of substance use disorders...
December 9, 2017: Acupuncture in Medicine: Journal of the British Medical Acupuncture Society
https://www.readbyqxmd.com/read/29223914/cannabis-use-disorder-and-male-sex-predict-medical-cannabis-card-status-in-a-sample-of-high-risk-adolescents
#9
Janet Kim, Marilyn E Coors, Susan E Young, Kristen M Raymond, Christian J Hopfer, Tamara L Wall, Robin P Corley, Sandra A Brown, Joseph T Sakai
OBJECTIVE: To examine if a substance use disorder (SUD), especially cannabis use disorder in adolescence, predicts future medical cannabis card status among high-risk youth. METHODS: Data collection occurred in Denver and San Diego. We recruited adolescents, with or at high risk for SUD and conduct problems (hereafter probands) and their siblings (n=654). Baseline (Wave 1) assessments took place between 1999 and 2008, and follow-up (Wave 2) took place between 2010 and 2013...
December 2, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29221791/online-effects-of-transcranial-direct-current-stimulation-on-prefrontal-metabolites-in-gambling-disorder
#10
Maya Dickler, Christophe Lenglos, Emmanuelle Renauld, Francine Ferland, Richard A Edden, Jean Leblond, Shirley Fecteau
Gambling disorder is characterized by persistent maladaptive gambling behaviors and is now considered among substance-related and addictive disorders. There is still unmet therapeutic need for these clinical populations, however recent advances indicate that interventions targeting the Glutamatergic/GABAergic system hold promise in reducing symptoms in substance-related and addictive disorders, including gambling disorder. There is some data indicating that transcranial direct current stimulation may hold clinical benefits in substance use disorders and modulate levels of brain metabolites including glutamate and GABA...
December 5, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/29216892/opiate-agonist-treatment-to-improve-health-of-individuals-with-opioid-use-disorder-in-lebanon
#11
Ali Ghaddar, Zeinab Abbas, Ramzi Haddad
BACKGROUND: Opioid agonist therapy has been widely used to reduce harms among individuals with opioid use disorder but its effectiveness has not been evaluated in the Middle East North African (MENA) region. This study aims to evaluate the effectiveness of a program using opioid agonist therapy in combination with psychosocial support on improving psychological and social well-being, reducing arrest, and reducing risky behavior in individuals with opioid use disorder in Lebanon. METHODS: A one-group pre-test post-test design study was performed at SKOUN Lebanese Addiction Centre between January 2013 and December 2014...
December 8, 2017: Harm Reduction Journal
https://www.readbyqxmd.com/read/29209752/-addiction-as-an-attachment-disorder
#12
REVIEW
H F Unterrainer, M Hiebler-Ragger, L Rogen, H P Kapfhammer
BACKGROUND: There is no commonly accepted model for describing the development and treatment of substance use disorders (SUD); however, over several decades the attachment theory has represented an important basis for the clinical handling of SUD. This study gives a systematic review of empirical studies regarding the relationship between SUD and disorders of attachment behavior. OBJECTIVE: Is there a positive relationship between disorders of attachment behavior and the presence of SUD? METHOD: Various databases (PsychInfo, Web of Science, PubMed) were systematically searched in order to pinpoint relevant studies in books and articles published in English or German...
December 5, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/29206183/gaming-device-usage-patterns-predict-internet-gaming-disorder-comparison-across-different-gaming-device-usage-patterns
#13
Soo-Hyun Paik, Hyun Cho, Ji-Won Chun, Jo-Eun Jeong, Dai-Jin Kim
Gaming behaviors have been significantly influenced by smartphones. This study was designed to explore gaming behaviors and clinical characteristics across different gaming device usage patterns and the role of the patterns on Internet gaming disorder (IGD). Responders of an online survey regarding smartphone and online game usage were classified by different gaming device usage patterns: (1) individuals who played only computer games; (2) individuals who played computer games more than smartphone games; (3) individuals who played computer and smartphone games evenly; (4) individuals who played smartphone games more than computer games; (5) individuals who played only smartphone games...
December 5, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29198186/screening-in-trauma-for-opioid-misuse-prevention-stomp-study-protocol-for-the-development-of-an-opioid-risk-screening-tool-for-victims-of-injury
#14
Randall Brown, Brienna Deyo, Chelsea Riley, Andrew Quanbeck, Joseph E Glass, Rebecca Turpin, Scott Hetzel, Christopher Nicholas, Maireni Cruz, Suresh Agarwal
BACKGROUND: Opioid addiction and overdose are epidemic in the U.S. Victims of traumatic injury are at greater than average risk for opioid misuse and related complications. Potential risk screens and preventive interventions in this clinical population remain under-investigated. The current project seeks to develop and pilot the implementation of a screening tool for opioid risk at American College of Surgeons (ACS) Level I and Level II trauma centers. METHODS: The project began with an online survey, which was sent to Wisconsin trauma center medical directors and trauma coordinators for the purpose of gathering information on current substance use screening practices...
December 4, 2017: Addiction Science & Clinical Practice
https://www.readbyqxmd.com/read/29197198/cardiovascular-disease-risk-factors-in-patients-with-posttraumatic-stress-disorder-ptsd-a-narrative-review
#15
Marina Šagud, Nenad Jakšić, Bjanka Vuksan-Ćusa, Mladen Lončar, Ivana Lončar, Alma Mihaljević Peleš, Davor Miličić, Miro Jakovljević
Posttraumatic stress disorder (PTSD) is a chronic condition related to severe stress and trauma. There is a mounting evidence about increased prevalence and mortality from cardiovascular diseases (CVD) in patients with PTSD. This review summarizes the current data on possible relations between PTSD and increased risks of CVD, including biological, psychological and behavioral factors. Biological factors refer to increased prevalence of metabolic syndrome (MetS), hypertension, elevation of pro-inflammatory cytokines and homocysteine levels...
December 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/29197196/analysis-of-the-prevalence-of-mental-disorders-in-psoriasis-the-relevance-of-psychiatric-assessment-in-dermatology
#16
Bárbara Roque Ferreira, José Luís Pio-Abreu, José Pedro Reis, Américo Figueiredo
BACKGROUND: The boundary between Dermatology and Psychiatry has increasing recognition. Psoriasis is a common psychophysiological skin disease with a major impact on patient's quality of life and a paradigmatic example of a pathology in that boundary. Studies are needed to exactly point out the prevalence of specific psychopathology and mental disorders associated with psoriasis. This work intends to analyse the prevalence of psychopathology and psychiatric comorbidities in patients with psoriasis...
December 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/29195595/factors-associated-with-victimization-in-dual-diagnosis-patients
#17
Marleen M de Waal, Carolien Christ, Jack J M Dekker, Martijn J Kikkert, Nick M Lommerse, Wim van den Brink, Anna E Goudriaan
BACKGROUND: Patients with a substance use disorder and co-occurring mental disorder are prone to victimization. There is a lack of research identifying variables related to violent and property victimization in this high risk group. The aim of this study was to identify factors associated with violent and property victimization in male and female dual diagnosis patients in order to identify targets for prevention. METHODS: In a cross-sectional study, victimization and demographic, clinical and psychological characteristics were assessed in 243 treatment-seeking patients with dual diagnosis...
January 2018: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/29195592/understanding-abuse-of-buprenorphine-naloxone-film-versus-tablet-products-using-data-from-asi-mv%C3%A2-substance-use-disorder-treatment-centers-and-radars%C3%A2-system-poison-centers
#18
Stephen F Butler, Ryan A Black, Stevan Geoffrey Severtson, Richard C Dart, Jody L Green
OBJECTIVES: The objectives were to examine the abuse prevalence and route-of-administration (ROA) profiles of sublingual buprenorphine/naloxone combination (BNX) film in comparison with the BNX tablet and to identify clinically-relevant subgroups of patients or geographic patterns. METHODS: Between Q1 2015 through Q3 2015, data were collected from two major surveillance systems: (1) assessment of individuals in substance use disorder (SUD) treatment collected from the National Addictions Vigilance Intervention and Prevention Program (NAVIPPRO®) ASI-MV® system and (2) intentional abuse/misuse exposures in the RADARS® System Poison Center Program...
January 2018: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/29194445/safety-and-efficacy-of-an-oxycodone-vaccine-addressing-some-of-the-unique-considerations-posed-by-opioid-abuse
#19
M D Raleigh, S J Peterson, M Laudenbach, F Baruffaldi, F I Carroll, S D Comer, H A Navarro, T L Langston, S P Runyon, S Winston, M Pravetoni, P R Pentel
Among vaccines aimed at treating substance use disorders, those targeting opioids present several unique medication development challenges. 1) Opioid overdose is a common complication of abuse, so it is desirable for an opioid vaccine to block the toxic as well as the addictive effects of opioids. 2) It is important that an opioid vaccine not interfere with the action of opioid antagonists used to reverse opioid overdose or treat addiction. 3) Some opioids are immunosuppressive and chronic ongoing opioid use could interfere with vaccine immunogenicity...
2017: PloS One
https://www.readbyqxmd.com/read/29185897/pharmacological-treatment-of-insomnia-symptoms-in-individuals-with-substance-use-disorders-in-spain-a-quasi-experimental-study
#20
L Grau-López, L Grau-López, C Daigre, R F Palma-Álvarez, L Rodriguez-Cintas, E Ros-Cucurull, C Roncero
INTRODUCTION: Pharmacological treatment of insomnia in patients with addictions has been hardly investigated and there are few researches about it in an inpatient detoxification. The aim of this study was to describe the outcomes of the pharmacological treatment of insomnia in SUD patients admitted to a detoxification unit in Spain, with a focus on the primary substance of abuse and co-occurring mental disorders. METHODS: A quasi-experimental study was conducted in 481 addicted in patients, who were admitted for substances detoxification in Vall d´Hebron University Hospital, Barcelona, Spain, from 2010 to 2015...
November 29, 2017: Substance Use & Misuse
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