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https://www.readbyqxmd.com/read/29150473/patient-level-and-practice-level-factors-associated-with-consultation-duration-a-cross-sectional-analysis-of-over-one-million-consultations-in-english-primary-care
#1
Sarah Stevens, Clare Bankhead, Toqir Mukhtar, Rafael Perera-Salazar, Tim A Holt, Chris Salisbury, F D Richard Hobbs
OBJECTIVES: Consultation duration has previously been shown to be associated with patient, practitioner and practice characteristics. However, previous studies were conducted outside the UK, considered only small numbers of general practitioner (GP) consultations or focused primarily on practitioner-level characteristics. We aimed to determine the patient-level and practice-level factors associated with duration of GP and nurse consultations in UK primary care. DESIGN AND SETTING: Cross-sectional data were obtained from English general practices contributing to the Clinical Practice Research Datalink (CPRD) linked to data on patient deprivation and practice staffing, rurality and Quality and Outcomes Framework (QOF) achievement...
November 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/29147800/the-pediatric-heart-failure-workforce-an-international-multicenter-survey
#2
Scott R Auerbach, Melanie D Everitt, Ryan J Butts, David N Rosenthal, Yuk M Law
Our objective was to understand the scope of pediatric heart failure (HF) and the current staffing environment of HF programs. An online survey was distributed to members of the Pediatric Heart Transplant Study and the Pediatric Council of the International Society for Heart and Lung Transplantation. All participants received the primary 23-question survey. Additionally, HF program directors received a 32-question supplemental survey. Of 235 invitations sent, there were 69 (29%) primary surveys and 34 program director surveys completed (24 U...
November 17, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29141629/the-potential-impact-of-brexit-and-immigration-policies-on-the-gp-workforce-in-england-a-cross-sectional-observational-study-of-gp-qualification-region-and-the-characteristics-of-the-areas-and-population-they-served-in-september-2016
#3
Aneez Esmail, Maria Panagioti, Evangelos Kontopantelis
BACKGROUND: The UK is dependent on international doctors, with a greater proportion of non-UK qualified doctors working in its universal health care system than in any other European country, except Ireland and Norway. The terms of the UK exit from the European Union can reduce the ability of European Economic Area (EEA) qualified doctors to work in the UK, while new visa requirements will significantly restrict the influx of non-EEA doctors. We aimed to explore the implications of policy restrictions on immigration, by regionally and spatially describing the characteristics of general practitioners (GPs) by region of medical qualification and the characteristics of the populations they serve...
November 16, 2017: BMC Medicine
https://www.readbyqxmd.com/read/29141048/microcirculation-in-open-vs-minimally-invasive-dorsal-stabilization-of-thoracolumbar-fractures
#4
Bergita Ganse, Miguel Pishnamaz, Philipp Kobbe, Christian Herren, Gertraud Gradl-Dietsch, Franziska Böhle, Bernd Johannes, Bong-Sung Kim, Klemens Horst, Matthias Knobe
Standard open and percutaneous minimally invasive surgical procedures co-exist in the treatment of fractures of the thoracolumbar spine. Shorter skin incisions just above the pedicles are used in minimally invasive procedures. Full-length skin incisions and invasive preparations are applied in the standard open approach. While both methods show equivalent rates of intraoperative surgical complications and comparable clinical and radiological outcomes, blood loss and operation time have shown to be decreased in minimally invasive treatment...
2017: PloS One
https://www.readbyqxmd.com/read/29135232/confocal-raman-microscopy-for-the-determination-of-protein-and-quaternary-ammonium-ion-loadings-in-biocatalytic-membranes-for-electrochemical-energy-conversion-and-storage
#5
Rong Cai, Sofiene Abdellaoui, Jay P Kitt, Cullen Irvine, Joel Harris, Shelley D Minteer, Carol Korzeniewski
The need to immobilize active enzyme, while ensuring high rates of substrate turnover and electronic charge transfer with an electrode, is a centrally important challenge in the field of bioelectrocatalysis. In this work, we demonstrate the use of confocal Raman microscopy as a tool for quantitation and molecular-scale structural characterization of ionomers and proteins within biocatalytic membranes to aid in the development of energy efficient biofuel cells. A set of recently available short side chain Aquivion ionomers spanning a range of equivalent weight (EW) suitable for enzyme immobilization was investigated...
November 14, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29128774/the-effect-of-hydraulic-retention-time-in-onsite-wastewater-treatment-and-removal-of-pharmaceuticals-hormones-and-phenolic-utility-substances
#6
H Ejhed, J Fång, K Hansen, L Graae, M Rahmberg, J Magnér, E Dorgeloh, G Plaza
Micropollutants such as pharmaceuticals, hormones and phenolic utility chemicals in sewage water are considered to be an emerging problem because of increased use and observed adverse effects in the environment. The study provides knowledge on the removal efficiency of micropollutants with a range of physical and chemical properties in three commercially available onsite wastewater treatment facilities (OWTFs), tested on influent wastewater collected from 2500 person equivalents in Bildchen, Germany. A longer hydraulic retention time would in theory be expected to have a positive effect, and this study presents results for three different OWTFs in full-scale comparable tests under natural conditions...
November 9, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29126665/risk-factors-for-unintentional-occupational-injury-among-urban-transit-bus-drivers-a-cohort-longitudinal-study
#7
Chia Wei, Susan G Gerberich, Andrew D Ryan, Bruce H Alexander, Timothy R Church, Michael Manser
PURPOSE: Although many studies have focused on bus operators' occupational diseases, work-related injury and associated risk factor data are limited. The purpose of this longitudinal study was to investigate unintentional injury and exposures that may affect injury risk among metropolitan bus operators. METHODS: Demographic, work-related, and injury data obtained from a metropolitan transit company for a 5-year period, enabled estimates of rates per 100 full time equivalents (FTEs) and adjusted Hazard Ratios (HRs), with 95% confidence intervals (CIs), using Generalized Estimating Equations and Cox proportional hazards models, respectively...
October 28, 2017: Annals of Epidemiology
https://www.readbyqxmd.com/read/29117610/-evaluation-of-ophthalmic-follow-up-care-of-former-pre-term-and-full-term-infants-aged-from-4-to-10-years-in-germany-results-of-the-wiesbaden-prematurity-study-wps
#8
Achim Fieß, Ruth Kölb-Keerl, Heike Maria Elflein, Alexander K Schuster, Markus Knuf, Bernd Kirchhof, Isabel Oberacher-Velten, Philipp S Muether, Jacqueline Bauer
Background The purpose of this investigation was to analyse the ophthalmic follow-up care of former pre-term and full-term born infants aged 4 to 10 years in the clinical practice and the comparison to the recommendations of the national ophthalmic guidelines. Methods For the prospective Wiesbaden Prematurity Study (WPS), 503 infants were examined: 239 former pre-term infants (PT) with gestational age (GA) ≤ 32 weeks and 264 former full-term born infants (FT) with a GA ≥ 37 weeks aged 4 to 10 years...
November 8, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/29096680/outcomes-in-randomised-controlled-trials-in-prevention-and-management-of-carious-lesions-a-systematic-review
#9
REVIEW
Colin Levey, Nicola Innes, Falk Schwendicke, Thomas Lamont, Gerd Göstemeyer
BACKGROUND: Inconsistent outcome reporting is one significant hurdle to combining results from trials into systematic reviews. Core outcome sets (COS) can reduce this barrier. The aim of this review was to map outcomes reported in caries prevention and management randomised controlled trials (RCT) as a first step to COS development. We also investigated RCT characteristics and reporting of primary outcomes and sample size calculations. METHODS: PubMed, Embase, Web of Knowledge and Cochrane CENTRAL were systematically searched (1 January 1968 to 25 August 2015)...
November 2, 2017: Trials
https://www.readbyqxmd.com/read/29054171/the-evolution-of-human-sleep-technological-and-cultural-innovation-associated-with-sleep-wake-regulation-among-hadza-hunter-gatherers
#10
David R Samson, Alyssa N Crittenden, Ibrahim A Mabulla, Audax Z P Mabulla
Sleep is necessary for the survival of all mammalian life. In humans, recent investigations have generated critical data on the relationship between sleep and ecology in small-scale societies. Here, we report the technological and social strategies used to alter sleep environments and influence sleep duration and quality among a population of hunter-gatherers, the Hadza of Tanzania. Specifically, we investigated the effects that grass huts, sound levels, and fire had on sleep. We quantitatively compared thermal stress in outdoor environments to that found inside grass hut domiciles to test whether the huts function as thermoregulated microhabitats during the rainy season...
December 2017: Journal of Human Evolution
https://www.readbyqxmd.com/read/29051004/assessing-time-of-full-renal-recovery-following-minimally-invasive-partial-nephrectomy
#11
Mark T Dawidek, Ernest Chan, Shawna L Boyle, Alp Sener, Patrick P Luke
OBJECTIVE: To assess renal function in the operated kidney at different time points post partial nephrectomy (PN) and establish the time in which optimal recovery occurs. Recovery of renal function post-PN has received significant attention. However, the optimal time to determine full recovery has not been clearly established. METHODS: Renal function following minimally invasive (laparoscopic and robotic) PNs performed between 2002 and 2015 was reviewed. Patients included in this study had renal function assessed pre-operatively as well as 3 days, 6-12 weeks, and 1 year post-PN, using a combination of estimated glomerular filtration rate (eGFR) from serum creatinine and relative renal uptake (RRU) from Tc99m-MAG3 renal scintigraphy...
October 16, 2017: Urology
https://www.readbyqxmd.com/read/29047340/occupational-blood-exposures-in-health-care-workers-incidence-characteristics-and-transmission-of-bloodborne-pathogens-in-south-korea
#12
Ju Hyun Lee, Junhyeon Cho, Yung Jung Kim, Sang Hyuk Im, Eun Sun Jang, Jin-Wook Kim, Hong Bin Kim, Sook-Hyang Jeong
BACKGROUND: Health care workers (HCWs) are at high risk for occupational blood exposures (OBEs) and transmission of bloodborne pathogens. This study elucidated the incidence rate and epidemiological characteristics of OBEs among HCWs and investigated the pathogen transmission rate for hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV). METHODS: Self-reported OBEs from January 1, 2011 to December 31, 2015 were obtained from the electronic recording system...
October 18, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29038830/a-distance-blended-learning-program-to-upgrade-the-clinical-competence-of-district-non-doctor-anesthesia-providers-in-nepal
#13
Shristi Shah, Stephen Knoble, Oliver Ross, Stephen Pickering
BACKGROUND: Across Nepal, anesthesia at a district level is provided mostly by non-doctor anesthesia providers (anesthesia assistants-AAs). Nepal's Government recognized the need to sustain competence with continuous professional development and to upgrade 6-month trained working AAs to professional equivalence with the new national standard of 12-month training. As they are essential district health workers and AA clinical training sites are full, an innovative distance blended learning, competency-based, upgrade 1-year course was developed and conducted in 2014-2017 for two batches...
December 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29037784/the-influence-of-registered-nurses-and-nurse-practitioners-on-patient-experience-with-primary-care-results-from-the-canadian-qualico-pc-study
#14
Mehdi Ammi, Sarah Ambrose, Bill Hogg, Sabrina Wong
Nurses, whether registered nurses (RNs) or nurse practitioners (NPs), are becoming key providers of primary care services. While evidence for the influence of NPs on patient experience in primary care is mounting, this is less so for RNs. We use the Canadian component of the international Quality and Costs of Primary Care 2013/14 survey to investigate the mechanisms by which nurses can affect patients' experience in primary care, focusing on accessibility and appropriateness of care. The data allow us to distinguish between family practice RNs, specialised RNs and NPs, and covers all types of patients visiting a primary care clinic in a variety of contexts in all Canadian provinces...
October 5, 2017: Health Policy
https://www.readbyqxmd.com/read/29036608/insights-into-rna-polymerase-catalysis-and-adaptive-evolution-gained-from-mutational-analysis-of-a-locus-conferring-rifampicin-resistance
#15
Olga Yurieva, Vadim Nikiforov, Vadim Nikiforov, Michael O'Donnell, Arkady Mustaev
S531 of Escherichia coli RNA polymerase (RNAP) β subunit is a part of RNA binding domain in transcription complex. While highly conserved, S531 is not involved in interactions within the transcription complex as suggested by X-ray analysis. To understand the basis for S531 conservation we performed systematic mutagenesis of this residue. We find that the most of the mutations significantly decreased initiation-to-elongation transition by RNAP. Surprisingly, some changes enhanced the production of full-size transcripts by suppressing abortive loss of short RNAs...
September 25, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/29027017/palladium-bionanoparticles-production-from-acidic-pd-ii-solutions-and-spent-catalyst-leachate-using-acidophilic-fe-iii-reducing-bacteria
#16
Naoko Okibe, Daisuke Nakayama, Takahiro Matsumoto
The acidophilic, Fe(III)-reducing heterotrophic bacteria Acidocella aromatica PFBC(T) and Acidiphilium cryptum SJH were utilized to produce palladium (Pd) bionanoparticles via a simple 1-step microbiological reaction. Monosaccharide (or intracellular NADH)-dependent reactions lead to visualization of intra/extra-cellular enzymatic Pd(0) nucleation. Formic acid-dependent reactions proceeded via the first slow Pd(0) nucleation phase and the following autocatalytic Pd(II) reduction phase regardless of the presence or viability of the cells...
November 2017: Extremophiles: Life Under Extreme Conditions
https://www.readbyqxmd.com/read/29022216/initial-evaluation-of-the-celesteion-large-bore-pet-ct-scanner-in-accordance-with-the-nema-nu2-2012-standard-and-the-japanese-guideline-for-oncology-fdg-pet-ct-data-acquisition-protocol-version-2-0
#17
Tomohiro Kaneta, Matsuyoshi Ogawa, Nobutoku Motomura, Hitoshi Iizuka, Tetsu Arisawa, Ayako Hino-Shishikura, Keisuke Yoshida, Tomio Inoue
BACKGROUND: The goal of this study was to evaluate the performance of the Celesteion positron emission tomography/computed tomography (PET/CT) scanner, which is characterized by a large-bore and time-of-flight (TOF) function, in accordance with the NEMA NU-2 2012 standard and version 2.0 of the Japanese guideline for oncology fluorodeoxyglucose PET/CT data acquisition protocol. Spatial resolution, sensitivity, count rate characteristic, scatter fraction, energy resolution, TOF timing resolution, and image quality were evaluated according to the NEMA NU-2 2012 standard...
October 11, 2017: EJNMMI Research
https://www.readbyqxmd.com/read/29017248/fluoroquinolone-resistance-mutation-detection-is-equivalent-to-culture-based-drug-sensitivity-testing-for-predicting-multidrug-resistant-tuberculosis-treatment-outcome-a-retrospective-cohort-study
#18
Maha R Farhat, Karen R Jacobson, Molly F Franke, Devinder Kaur, Megan Murray, Carole D Mitnick
Background: Molecular diagnostics that rapidly and accurately predict fluoroquinolone (FQ) resistance promise to improve treatment outcomes for individuals with multidrug-resistant (MDR) tuberculosis (TB). Mutations in the gyr genes, though, can cause variable levels of in vitro FQ resistance, and some in vitro resistance remains unexplained by gyr mutations alone, but the implications of these discrepancies for treatment outcome are unknown. Methods: We performed a retrospective cohort study of 172 subjects with MDR/extensively drug-resistant TB subjects and sequenced the full gyrA and gyrB open reading frames in their respective sputum TB isolates...
October 15, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28992658/-the-pl%C3%A3-ner-model-for-the-school-entry-screening-is-a-role-model-for-the-future
#19
Josef Weigl
Background The Plöner Model is a stepwise-selective model, similar to the one practised in all of Bavaria since 2008. It was already developed in 2002/2003 for the school entry screening and has been in use since then. Such models are intermittently criticized since not each child is seen by a doctor. Methods The procedure and data of the Plöner Model are analyzed and put into a wider context within Germany and beyond. The current programs in place are therefore categorized into 3 groups and compared with regard to public heath ethics criteria...
October 9, 2017: Das Gesundheitswesen
https://www.readbyqxmd.com/read/28986653/pool-size-ratio-of-the-substantia-nigra-in-parkinson-s-disease-derived-from-two-different-quantitative-magnetization-transfer-approaches
#20
Paula Trujillo, Paul E Summers, Alex K Smith, Seth A Smith, Luca T Mainardi, Sergio Cerutti, Daniel O Claassen, Antonella Costa
PURPOSE: We sought to measure quantitative magnetization transfer (qMT) properties of the substantia nigra pars compacta (SNc) in patients with Parkinson's disease (PD) and healthy controls (HCs) using a full qMT analysis and determine whether a rapid single-point measurement yields equivalent results for pool size ratio (PSR). METHODS: Sixteen different MT-prepared MRI scans were obtained at 3 T from 16 PD patients and eight HCs, along with B1, B0, and relaxation time maps...
December 2017: Neuroradiology
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