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Transitional urology

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https://www.readbyqxmd.com/read/27800063/a-proposed-solution-to-a-urological-tightrope-walk-the-challenge-of-transition-of-spina-bifida-patients-from-pediatric-to-adult-care-in-ontario
#1
REVIEW
Martin A Koyle, Nicole Golda, Christopher Hillis, Betty Oldershaw, Margaret DeMelo, Jennifer Uyeno
No abstract text is available yet for this article.
September 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/27800049/comparing-transition-of-care-from-adolescence-to-adulthood-for-patients-with-congenital-urological-conditions-in-canada-and-the-u-s
#2
Rosalia Misseri
No abstract text is available yet for this article.
September 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/27800048/a-proposed-solution-to-a-urological-tightrope-walk-the-challenge-of-transition-of-spina-bifida-patients-from-pediatric-to-adult-care-in-ontario
#3
REVIEW
Martin A Koyle, Nicole Golda, Christopher Hillis, Betty Oldershaw, Margaret DeMelo, Jennifer Uyeno
No abstract text is available yet for this article.
September 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/27800045/advocating-for-transition-of-care-in-urology
#4
EDITORIAL
D Robert Siemens
No abstract text is available yet for this article.
September 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/27749363/leading-contributors-to-success-of-transitional-urology-units
#5
Dan Wood
PURPOSE OF REVIEW: There is increasing recognition of the need for life-long care in patients who have congenital urological anomalies. This study looks at the factors surrounding transition and suggests those, which may improve the success. RECENT FINDINGS: One of the most challenging phases in this care is adolescence. There are the physical and psychological changes that all adolescents go through. Patients need medical surveillance through this time in order to ensure good care and patient safety...
January 2017: Current Opinion in Urology
https://www.readbyqxmd.com/read/27672439/zinner-s-syndrome-report-of-two-cases-and-review-of-the-literature
#6
Amine Slaoui, Souhail Regragui, Abdelouahad Lasri, Tarik Karmouni, Khalid El Khader, Abdellatif Koutani, Ahmed Ibn Attya
BACKGROUND: Congenital malformations of the seminal vesicle are uncommon, and most of them are cystic malformations. If an insult occurs between the 4th and the 13 h gestational week, the embryogenesis of the kidney, ureter, seminal vesicle, and vas deferens could be altered. Cysts of the seminal vesicle may appear with a mass effect, dysuria, epididymitis, or obstruction of the gastrointestinal and genitourinary tracts. Approximately two thirds of them are associated with ipsilateral renal agenesis, because both the ureteral buds and seminal vesicles originate from the mesonephric (Wolffian) duct...
2016: Basic and Clinical Andrology
https://www.readbyqxmd.com/read/27665407/-urologic-malignancies-in-renal-transplant-candidates-and-recipients
#7
F Kleinclauss, R Thuret, T Murez, M O Timsit
OBJECTIVE: To review epidemiology and management of urologic neoplasms in renal transplant candidates and recipients. MATERIAL AND METHODS: Relevant publications were identified through Medline (http://www.ncbi.nlm.nih.gov) and Embase (http://www.embase.com) database using the following keywords, alone or in association, "neoplasms"; "prostate cancer"; "renal carcinoma"; "renal transplantation"; "transitional carcinoma"; "waiting list". Articles were selected according to methods, language of publication and relevance...
September 21, 2016: Progrès en Urologie
https://www.readbyqxmd.com/read/27588140/il-8-induces-the-epithelial-mesenchymal-transition-of-renal-cell-carcinoma-cells-through-the-activation-of-akt-signaling
#8
Nan Zhou, Fuding Lu, Cheng Liu, Kewei Xu, Jian Huang, Dexin Yu, Liangkuan Bi
The epithelial-mesenchymal transition (EMT) process has increasingly been examined due to its role in the progression of human tumors. Renal cell carcinoma (RCC) is one of the most common urological tumors that results in patient mortality. Previous studies have demonstrated that the EMT process is closely associated with the metastasis of RCC; however, the underlying molecular mechanism has not been determined yet. The present study revealed that interleukin (IL)-8 was highly expressed in metastatic RCC. IL-8 could induce the EMT of an RCC cell line by enhancing N-cadherin expression and decreasing E-cadherin expression...
September 2016: Oncology Letters
https://www.readbyqxmd.com/read/27576024/exposure-to-and-attitudes-regarding-transgender-education-among-urology-residents
#9
Geolani W Dy, Nathan C Osbun, Shane D Morrison, David W Grant, Paul A Merguerian
INTRODUCTION: Transgender individuals are underserved within the health care system but might increasingly seek urologic care as insurers expand coverage for medical and surgical gender transition. AIM: To evaluate urology residents' exposure to transgender patient care and their perceived importance of transgender surgical education. METHODS: Urology residents from a representative sample of U.S. training programs were asked to complete a cross-sectional survey from January through March 2016...
October 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/27572476/spop-promotes-tumor-progression-via-activation-of-%C3%AE-catenin-tcf4-complex-in-clear-cell-renal-cell-carcinoma
#10
Wencai Zhao, Jiancheng Zhou, Zhuo Deng, Yang Gao, Yongyi Cheng
Renal cell carcinoma (RCC) is the most common type of kidney cancer, about one third of the cases are diagnosed at advanced stages with metastases and effective treatments for metastatic RCC are lacking. The molecular events supporting RCC progression remain poorly understood. SPOP, an E3 ubiquitin ligase component, was recently showed to sufficiently promote RCC tumorigenesis, however, other potential functions of SPOP in RCC have not been studied. In the present investigation, by assessing the immunohistochemical staining of SPOP in urological tumors, we found the protein was highly expressed in RCC, in particular, it was specifically expressed in clear cell RCC...
September 2016: International Journal of Oncology
https://www.readbyqxmd.com/read/27527226/is-internet-pornography-causing-sexual-dysfunctions-a-review-with-clinical-reports
#11
Brian Y Park, Gary Wilson, Jonathan Berger, Matthew Christman, Bryn Reina, Frank Bishop, Warren P Klam, Andrew P Doan
Traditional factors that once explained men's sexual difficulties appear insufficient to account for the sharp rise in erectile dysfunction, delayed ejaculation, decreased sexual satisfaction, and diminished libido during partnered sex in men under 40. This review (1) considers data from multiple domains, e.g., clinical, biological (addiction/urology), psychological (sexual conditioning), sociological; and (2) presents a series of clinical reports, all with the aim of proposing a possible direction for future research of this phenomenon...
August 5, 2016: Behavioral Sciences
https://www.readbyqxmd.com/read/27517862/transitional-urology-for-male-adolescents-what-adult-urologists-should-know
#12
REVIEW
Kristina D Suson
In recent years, there has been increasing interest in transitional urology, or how to best prepare patients with major congenital urologic diseases, such as bladder exstrophy and neuropathic bladder, to manage their own health care with adult urologists. However, common pediatric urologic conditions may be encountered by the adult urologist with more regularity. This review focuses on three relatively common conditions which may be identified in childhood, the consequences from which a patient may seek help from an adult urologist: cryptorchidism, varicocele, and Klinefelter syndrome...
October 2016: Current Urology Reports
https://www.readbyqxmd.com/read/27461645/a-clinicoepidemiological-study-of-young-age-bladder-tumors-an-eastern-indian-scenario
#13
Jitendra Pratap Singh, Vinod Priyadarshi, Dilip Kumar Pal
INTRODUCTION: Though, bladder cancer is one of the most common urological malignancies, studies addressing the young age group bladder tumors are rare. Present study was done to determine the clinicoepidemiological aspects of bladder tumor diagnosed in young age patients and to compare these aspects with elderly patients. PATIENTS AND METHODS: Patients with urinary bladder tumor were selectively divided into two groups; young (<40 years) and elderly (>60 years)...
April 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/27450943/non-muscular-invasive-urothelial-carcinoma-of-the-bladder-in-pediatric-and-young-adult-patients-age-related-outcomes
#14
Paolo Caione, Giulio Patruno, Vincenzo Pagliarulo, Anna Lavinia Bulotta, Annamaria Salerno, Francesca Diomedi Camassei, Gaetano Lastilla, Simona Gerocarni Nappo
OBJECTIVE: To report a two pediatric urology referral centers experience on transitional cell bladder carcinoma (TCCB) in patients younger than 30 years, focusing on age-related prognostic factors. MATERIALS AND METHODS: We reviewed patients younger than 30 years affected by TCCB from January 1999 to December 2011 were investigated. Spearman's rank test and Kruskal-Wallis test were adopted for statistical analysis. RESULTS: Eighteen patients were identified (8 females, 10 males) and stratified by age at presentation: five in group A (12 year old and younger), 7 in group B (13-19 years) and 6 in group C (20-29 years)...
July 19, 2016: Urology
https://www.readbyqxmd.com/read/27367032/capsaicin-triggers-autophagic-cell-survival-which-drives-epithelial-mesenchymal-transition-and-chemoresistance-in-bladder-cancer-cells-in-an-hedgehog-dependent-manner
#15
Consuelo Amantini, Maria Beatrice Morelli, Massimo Nabissi, Claudio Cardinali, Matteo Santoni, Angela Gismondi, Giorgio Santoni
Bladder cancer (BC) is a common urologic tumor characterized by high risk of recurrence and mortality. Capsaicin (CPS), used as an intravesical drug for overactive bladder, was demonstrated to induce cell death in different cancer cells including BC cells.Here we found that treatment of high-grade BC cells with high dose of CPS triggers autophagy. Infact, the CPS treatment alters the redox homeostasis by inducing production of radicals, mitochondrial depolarization, alterations of ADP/ATP ratio and activation of AMPK pathway stimulating the autophagic process in BC cells...
June 29, 2016: Oncotarget
https://www.readbyqxmd.com/read/27319973/itraq-based-quantitative-proteomic-analysis-reveals-potential-early-diagnostic-markers-of-clear-cell-renal-cell-carcinoma
#16
Limin Zhang, Haowen Jiang, Gang Xu, Nan Chu, Ningxing Xu, Hui Wen, Bin Gu, Jun Liu, Shanghua Mao, Rong Na, Yan Jing, Qiang Ding, Yuanfang Zhang, Ling Wang
Early detection is the key to improve the prognosis of kidney cancer. This study profiled and identified differentially expressed serum proteins in stage T1a renal cell carcinoma (RCC) using isobaric tags for relative and absolute quantification (iTRAQ)-based mass spectrometry. A total amount of 99 serum samples including 29 patients with ccRCC, 24 patients with a benign kidney mass, 28 patients with another type of urological tumor (20 cases of transitional cell carcinoma and 8 cases of prostate cancer or a male genital tumor), and 18 healthy controls were subjected to iTRAQ-based mass spectrometry...
July 19, 2016: Bioscience Trends
https://www.readbyqxmd.com/read/27276694/a-framework-for-transitioning-patients-from-pediatric-to-adult-health-settings-for-patients-with-neurogenic-bladder
#17
Jennifer Lewis, Dominic Frimberger, Emily Haddad, Gennady Slobodov
BACKGROUND: Adolescents with neurogenic bladder are a vulnerable population that severely lacks consistent transitional care from pediatric to adult urology settings. AIMS: Our practice determined that 100 patients with spina bifida and other neurogenic bladder conditions were not appropriately transferred to the adult setting once reaching adulthood. METHODS: We initiated a transitional program to establish a dedicated and formal process for adolescent patients to transition to adult urology...
June 8, 2016: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/27270070/barriers-to-transition-in-young-adults-with-neurogenic-bladder
#18
G M Grimsby, R Burgess, S Culver, B J Schlomer, M A Jacobs
INTRODUCTION: 'Transition' not only involves finding an adult healthcare provider, but also includes the process of developing the patient's ability to care for him/herself. Recent literature states that 40% of young adults with special healthcare needs are receiving the tools needed for transition. Pediatric urologists treating patients with complex anomalies, such as spina bifida, often anticipate poor outcomes for patients who are ill equipped for transition to adult care. The goal of this study was to identify potential barriers for young adults with neurogenic bladder when transitioning to independent care...
August 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/27261794/pediatric-urology-for-the-general-surgeon
#19
REVIEW
David J Chalmers, Vijaya M Vemulakonda
Pediatric urology spans the neonatal period through the transition into early adulthood. There are a variety of common pediatric urologic conditions that overlap significantly with pediatric surgery. This article reviews the pertinent pathophysiology of a few key disease processes, including the pediatric inguinal hernia and/or hydrocele, cryptorchidism, and circumcision. General surgeons may find themselves in the position of managing these problems primarily, particularly in rural areas that may lack pediatric subspecialization...
June 2016: Surgical Clinics of North America
https://www.readbyqxmd.com/read/27256204/comparison-of-pathological-outcomes-for-men-with-low-risk-prostate-cancer-from-diverse-practice-settings-similar-results-from-immediate-prostatectomy-or-initial-surveillance-with-delayed-prostatectomy
#20
Gregory B Auffenberg, Susan Linsell, Apoorv Dhir, Stacie N Myers, Bradley Rosenberg, David C Miller
PURPOSE: We compared pathological outcomes after radical prostatectomy for a population based sample of men with low risk prostate cancer initially on active surveillance and undergoing delayed prostatectomy vs those treated with immediate surgery in order to better understand this expectant management approach outside of the context of academic cohorts. We hypothesized that delays in surgery due to initial surveillance would not impact surgical pathological outcomes. MATERIALS AND METHODS: We performed a prospective cohort study of 2 groups of patients with NCCN low risk prostate cancer from practices in the Michigan Urological Surgery Improvement Collaborative, that is 1) men who chose initial active surveillance and went on to delayed prostatectomy and 2) men who chose immediate prostatectomy...
November 2016: Journal of Urology
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