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https://www.readbyqxmd.com/read/29330230/reducing-sedentary-behaviour-to-decrease-chronic-low-back-pain-the-stand-back-randomised-trial
#1
Bethany Barone Gibbs, Andrea L Hergenroeder, Sophy J Perdomo, Robert J Kowalsky, Anthony Delitto, John M Jakicic
OBJECTIVE: The Stand Back study evaluated the feasibility and effects of a multicomponent intervention targeting reduced prolonged sitting and pain self-management in desk workers with chronic low back pain (LBP). METHODS: This randomised controlled trial recruited 27 individuals with chronic LBP, Oswestry Disability Index (ODI) >10% and desk jobs (sitting ≥20 hours/week). Participants were randomised within strata of ODI (>10%-<20%, ≥20%) to receive bimonthly behavioural counselling (in-person and telephone), a sit-stand desk attachment, a wrist-worn activity-prompting device and cognitive behavioural therapy for LBP self-management or control...
January 12, 2018: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29326768/streptococcus-constellatus-spondylodiscitis-in-a-teenager-a-case-report
#2
S W Lim, H Y Lim, T Kannaiah, Z Zuki
Streptococcus constellatus is an extremely rare cause of pyogenic spondylodiscitis. Literature search yielded only one case report in an elderly 72 years old man with spontaneous T10-T11 S. constellatus spondylodiscitis. It is virtually unheard of in young teenage. We report the case of a 14 years old male teenager who presented with worsening low back pain for one year with no neurological deficit. Imaging studies were consistent with features of L4-L5 spondylodiscitis. CT guided biopsy grew a pure culture of streptococcus constellatus sensitive to penicillin and erythromycin...
November 2017: Malaysian Orthopaedic Journal
https://www.readbyqxmd.com/read/29324082/sensory-dissociation-in-chronic-low-back-pain-two-case-reports
#3
Wacław M Adamczyk, Kerstin Luedtke, Oskar Saulicz, Edward Saulicz
Patients with chronic low back pain often report that they do not perceive their painful back accurately. Previous studies confirmed that sensory dissociation and/or discrepancy between perceived body image and actual size is one of the specific traits of patients with chronic pain. Current approaches for measuring sensory dissociation are limited to two-point-discrimination or rely on pain drawings not allowing for quantitative analysis. This case study reports the sensory dissociation of two cases with chronic low back pain using a recently published test (point-to-point-test (PTP)) and a newly developed test (two-point-estimation (TPE))...
January 11, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29322966/the-influence-of-adjunctive-caudal-epidural-steroid-injection-on-the-therapeutic-effect-of-transforaminal-epidural-steroid-injection
#4
Atilla Kircelli, Tufan Cansever, Cem Yılmaz
BACKGROUND: Epidural steroid injection is widely used to treat the short and long-term symptoms of low back and radicular pain. To the best of our knowledge, the influence of transforaminal epidural steroid injection (TFSI) combined with caudal epidural steroid injection (CESI) on pain intensity, patient satisfaction, and quality of life in lumbar radiculopathy has not been examined. AIM: To evaluate the short and long-term efficacy of TFSI, and TFSI combined with CESI (TFSI + CESI) in patients with lumbar radiculopathy...
January 2018: Neurology India
https://www.readbyqxmd.com/read/29322254/the-effects-of-the-calcium-magnesium-bicarbonate-content-in-thermal-mineral-water-on-chronic-low-back-pain-a-randomized-controlled-follow-up-study
#5
Gáti Tamás, Tefner Ildikó Katalin, Kovács Lajos, Hodosi Katalin, Bender Tamás
The aim of this study was to investigate the effects of balneotherapy on chronic low back pain. This is a minimized, follow-up study evaluated according to the analysis of intention to treat. The subjects included in the study were 105 patients suffering from chronic low back pain. The control group (n = 53) received the traditional musculoskeletal pain killer treatment, while the target group (n = 52) attended thermal mineral water treatment for 3 weeks for 15 occasions on top of the usual musculoskeletal pain killer treatment...
January 10, 2018: International Journal of Biometeorology
https://www.readbyqxmd.com/read/29321099/non-specific-low-back-pain
#6
Jean-François Chenot, Bernhard Greitemann, Bernd Kladny, Frank Petzke, Michael Pfingsten, Susanne Gabriele Schorr
BACKGROUND: For many years, low back pain has been both the leading cause of days lost from work and the leading indication for medical rehabilitation. The goal of the German Disease Management Guideline (NDMG) on nonspecific low back pain is to improve the treatment of patients with this condition. METHODS: The current update of the NDMG on non-specific low back pain is based on articles retrieved by a systematic search of the literature for systematic reviews...
December 25, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/29319387/relationship-between-physical-activity-disability-and-physical-fitness-profile-in-sedentary-latina-breast-cancer-survivors
#7
Alexis Ortiz, Maribel Tirado, Daniel C Hughes, Velda Gonzalez, JaeJoon Song, Scherezade K Mama, Karen Basen-Engquist
OBJECTIVE: To report baseline data from a physical activity (PA) intervention for Latina breast cancer survivors, and assess the relationship between PA, fitness, and disability. METHODS: Eighty-nine Latina breast cancer survivors from San Juan, PR and Houston, TX (age: 55.4 ± 9.9 years; BMI: 29.87 ± 5.62 kg/m2; ≥ 3 months post-treatment) participated in this study. At baseline participants completed fitness testing (six-minute walk test [6MWT], 30-second sit-stand; grip strength, lower and upper extremity and low back strength, shoulder range of motion, balance testing), and assessment of physical activity (PA) and disability...
January 10, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29318608/functional-analysis-and-treatment-of-problem-behavior-related-to-mands-for-rearrangement
#8
REVIEW
Mariana Torres-Viso, Craig W Strohmeier, Jennifer R Zarcone
This study is a systematic replication of a functional analysis (FA) of the relation between mands and problem behavior. We extended treatment approaches for this problem behavior function, and describe the treatment of problem behavior related to mands for rearrangement demonstrated by a 12-year-old girl with autism spectrum disorder and Smith-Magenis syndrome. The mands consisted of requests for others to change their body positioning or proximity, or rearrange items back to their original position. An FA confirmed the relation between problem behavior and mand compliance, and functional communication training with extinction decreased problem behavior and increased functional communication responses...
January 10, 2018: Journal of Applied Behavior Analysis
https://www.readbyqxmd.com/read/29317362/lumbar-dorsal-root-ganglion-block-as-a-prognostic-tool-prior-to-pulsed-radiofrequency-a-randomized-prospective-and-comparative-study-on-cost-effectiveness
#9
Cheng-Chia Lee, Ching-Jen Chen, Chien-Chen Chou, Hsin-Yi Wang, Wen-Yuh Chung, Giia-Sheun Peng, Ching-Po Lin
OBJECTIVES: In the study, we discuss the predictive value and cost-effectiveness of dorsal root ganglion (DRG) blocks prior to using dorsal root ganglion pulsed radiofrequency (DRG-PRF) in the treatment of low back pain. METHODS: The study comprised 60 patients with low back pain who were randomly assigned into two groups. Patients in Group 1 were screened using DRG block prior to DRG-PRF treatment for responders. Patients in Group 2 underwent DRG-PRF treatment without DRG block...
January 6, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29317361/intraarticular-pulsed-radiofrequency-to-treat-refractory-lumbar-facet-joint-pain-in-patients-with-low-back-pain
#10
Min Cheol Chang, Yun-Woo Cho, Da Hyun Ahn, Kyung Hee Do
OBJECTIVE: Many treatment techniques have been used for refractory lumbar facet joint pain; however, their efficacy has been controversial. In this study, we investigated the clinical efficacy and safety of intraarticular pulsed radiofrequency for the treatment of refractory lumbar facet joint pain in patients with low back pain. METHODS: Twenty patients with refractory lumbar facet joint pain were recruited and each patient was treated using intraarticular pulsed radiofrequency...
January 6, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29317286/the-a-enth-domain-containing-protein-ateca4-is-an-adaptor-protein-involved-in-cargo-recycling-from-the-trans-golgi-network-early-endosome-to-the-plasma-membrane
#11
Hong Hanh Nguyen, Myoung Hui Lee, Kyungyoung Song, Gyeongik Ahn, Jihyeong Lee, Inhwan Hwang
Endocytosis and subsequent trafficking pathways are crucial for regulating the activity of plasma membrane-localized proteins. Depending on cellular and physiological conditions, the internalized cargoes are sorted at (and transported from) the trans-Golgi network/early endosome (TGN/EE) to the vacuole for degradation or recycled back to the plasma membrane. How this occurs at the molecular level remains largely elusive. Here we provide evidence that the ENTH domain-containing protein AtECA4 plays a crucial role in recycling cargoes from the TGN/EE to the plasma membrane...
January 6, 2018: Molecular Plant
https://www.readbyqxmd.com/read/29310946/validation-of-lumbar-spine-loading-from-a-musculoskeletal-model-including-the-lower-limbs-and-lumbar-spine
#12
Jason A Actis, Jasmin D Honegger, Deanna H Gates, Anthony J Petrella, Luis A Nolasco, Anne K Silverman
Low back mechanics are important to quantify to study injury, pain and disability. As in vivo forces are difficult to measure directly, modeling approaches are commonly used to estimate these forces. Validation of model estimates is critical to gain confidence in modeling results across populations of interest, such as people with lower-limb amputation. Motion capture, ground reaction force and electromyographic data were collected from ten participants without an amputation (five male/five female) and five participants with a unilateral transtibial amputation (four male/one female) during trunk-pelvis range of motion trials in flexion/extension, lateral bending and axial rotation...
December 13, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/29303471/comparison-of-percutaneous-endoscopic-transforaminal-discectomy-microendoscopic-discectomy-and-microdiscectomy-for-symptomatic-lumbar-disc-herniation-minimum-2-year-follow-up-results
#13
Xinyu Liu, Suomao Yuan, Yonghao Tian, Lianlei Wang, Liangtai Gong, Yanping Zheng, Jianmin Li
OBJECTIVE This study aimed to evaluate the clinical outcomes of percutaneous endoscopic transforaminal discectomy (PETD), microendoscopic discectomy (MED), and microdiscectomy (MD) for treatment of symptomatic lumbar disc herniation (LDH). METHODS One hundred ninety-two patients with symptomatic LDH at L3-4 and L4-5 were included in this study. The mean (± SD) age of patients was 34.2 ± 2.6 years (range 18-62 years). The patients were divided into groups as follows: group A was treated with PETD and included 60 patients (31 men and 29 women) with a mean age of 36...
January 5, 2018: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29301780/multiparametric-analysis-of-permeability-and-adc-histogram-metrics-for-classification-of-pediatric-brain-tumors-by-tumor-grade
#14
S Vajapeyam, D Brown, P R Johnston, K I Ricci, M W Kieran, H G W Lidov, T Y Poussaint
BACKGROUND AND PURPOSE: Accurate tumor grading is essential for treatment planning of pediatric brain tumors. We hypothesized that multiparametric analyses of a combination of permeability metrics and ADC histogram metrics would differentiate high- and low-grade tumors with high accuracy. MATERIALS AND METHODS: DTI and dynamic contrast-enhanced MR imaging using T1-mapping with flip angles of 2°, 5°, 10°, and 15°, followed by a 0.1-mmol/kg body weight gadolinium-based bolus was performed on all patients in addition to standard MR imaging...
January 4, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29299090/correction-of-grade-2-spondylolisthesis-following-a-non-surgical-structural-spinal-rehabilitation-protocol-using-lumbar-traction-a-case-study-and-selective-review-of-literature
#15
Curtis Fedorchuk, Douglas F Lightstone, Christi McRae, Derek Kaczor
Objective: Discuss the use of non-surgical spinal rehabilitation protocol in the case of a 69-year-old female with a grade 2 spondylolisthesis. A selective literature review and discussion are provided. Clinical Features: A 69-year-old female presented with moderate low back pain (7/10 pain) and severe leg cramping (7/10 pain). Initial lateral lumbar x-ray revealed a grade 2 spondylolisthesis at L4-L5 measuring 13.3 mm. Interventions and Outcomes: The patient completed 60 sessions of Mirror Image® spinal exercises, adjustments, and traction over 45 weeks...
May 2017: Journal of Radiology Case Reports
https://www.readbyqxmd.com/read/29298959/lumbar-model-generator-a-tool-for-the-automated-generation-of-a-parametric-scalable-model-of-the-lumbar-spine
#16
C E Lavecchia, D M Espino, K M Moerman, K M Tse, D Robinson, P V S Lee, D E T Shepherd
Low back pain is a major cause of disability and requires the development of new devices to treat pathologies and improve prognosis following surgery. Understanding the effects of new devices on the biomechanics of the spine is crucial in the development of new effective and functional devices. The aim of this study was to develop a preliminary parametric, scalable and anatomically accurate finite-element model of the lumbar spine allowing for the evaluation of the performance of spinal devices. The principal anatomical surfaces of the lumbar spine were first identified, and then accurately fitted from a previous model supplied by S14 Implants (Bordeaux, France)...
January 2018: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/29290127/image-guidance-in-transdiscal-fixation-for-high-grade-spondylolisthesis-in-adults-with-correct-spinal-balance
#17
Juan Delgado-Fernández, Paloma Pulido, María Ángeles García-Pallero, Guillermo Blasco, Natalia Frade-Porto, Rafael G Sola
OBJECTIVE Spondylolisthesis is a prevalent spine disease that recent studies estimate could be detected in 9% of the population. High-grade spondylolisthesis (HGS), however, is much less frequent, which makes it difficult to develop a general recommendation for its treatment. Posterior transdiscal fixation was proposed in 1994 for HGS, and the use of spine navigation could make this technique more accessible and reduce the morbidity associated with the procedure. The purpose of this study was to present a case series involving adult patients with HGS and correct spinal alignment who were treated with transdiscal pedicle screw placement guided with neuronavigation and compare the results to those achieved previously without image guidance...
January 2018: Neurosurgical Focus
https://www.readbyqxmd.com/read/29289414/a-qualitative-study-of-doctors-of-chiropractic-in-a-nova-scotian-practice-based-research-network-barriers-and-facilitators-to-the-screening-and-management-of-psychosocial-factors-for-patients-with-low-back-pain
#18
Peter Stilwell, Jill A Hayden, Piaf Des Rosiers, Katherine Harman, Simon D French, Janet A Curran, Warren Hefford
OBJECTIVES: This study aimed to assess chiropractors' awareness of clinical practice guidelines for low back pain and to identify barriers and facilitators to the screening and management of psychosocial factors in patients with low back pain. METHODS: This qualitative study used semi-structured interviews informed by the Theoretical Domains Framework with 10 Nova Scotian chiropractors who were members of a practice-based research network. RESULTS: The participants correctly identified what the guidelines generally recommend and described the value of psychosocial factors; however, none of the participants could name specific clinical practice guidelines for low back pain...
December 27, 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/29288862/variability-in-surgical-treatment-of-spondylolisthesis-among-spine-surgeons
#19
Daniel Lubelski, Vincent Alentado, Seth Williams, Colin O'Rourke, Nancy Obuchowski, Jeffrey C Wang, Michael Steinmetz, Alfred Melillo, Edward Benzel, Michael Modic, Robert Quencer, Thomas Mroz
BACKGROUND: There are a multitude of treatments for low grade lumbar spondylolisthesis. There are no clear guidelines for the optimal approach. OBJECTIVE: To identify the surgical treatment patterns for spondylolisthesis, among United States spine surgeons METHODS: 445 US spine surgeons completed a survey of clinical/radiographic case scenarios on patients with lumbar spondylolisthesis with neurogenic claudication with (S+BP) or without (S-BP) associated mechanical back pain...
December 27, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29287687/an-overview-of-the-possible-therapeutic-role-of-sumoylation-in-the-treatment-of-alzheimer-s-disease
#20
REVIEW
S Marcelli, E Ficulle, L Piccolo, M Corbo, M Feligioni
Nowadays, Alzheimer's disease (AD) is recognized as a multifactorial neurological pathology whose complexity is the cause of our still low achievements in the understanding of the associated mechanisms as well the discovery of a possible definitive cure. Clinicians are aware of the few possibilities offered by medicine to cure Alzheimer's patients, restore their memory and take them back to normal life. Unfortunately, the therapeutic tools available today are not able to contrast the pathology. In the last years the tendency of the research is to formulate new hypotheses that can help to develop future effective drugs...
December 26, 2017: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
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