keyword
MENU ▼
Read by QxMD icon Read
search

Medicines

keyword
https://www.readbyqxmd.com/read/29332348/sorafenib-combined-with-radiofrequency-ablation-as-treatment-for-patients-with-hepatocellular-carcinoma-a-systematic-review-and-meta-analysis
#1
Lin Chen, Xingming Ma, Xin Liu, Xiaomeng Cui
PURPOSE: To evaluate the safety and efficacy of a combination of sorafenib and radiofrequency ablation (RFA) in patients with hepatocellular carcinoma (HCC). METHODS: A systematic literature search was conducted using PubMed, Embase, the Cochrane Library, China National Knowledge Infrastructure (CNKI), China Biology Medicine disc (CBMdisc), WanFang Database, for all years up to January 2017. Pooled analyses of overall survival (OS), tumor- free survival, recurrence rates and adverse events were performed...
November 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/29332237/acute-acetaminophen-ingestion-improves-performance-and-muscle-activation-during-maximal-intermittent-knee-extensor-exercise
#2
Paul T Morgan, Joanna L Bowtell, Anni Vanhatalo, Andrew M Jones, Stephen J Bailey
AIM: Acetaminophen is a commonly used medicine for pain relief and emerging evidence suggests that it may improve endurance exercise performance. This study investigated some of the physiological mechanisms by which acute acetaminophen ingestion might blunt muscle fatigue development. METHODS: Thirteen active males completed 60 × 3 s maximum voluntary contractions (MVC) of the knee extensors with each contraction separated by a 2 s passive recovery period...
January 13, 2018: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29332222/efficacy-of-crocus-sativus-saffron-in-treatment-of-major-depressive-disorder-associated-with-post-menopausal-hot-flashes-a-double-blind-randomized-placebo-controlled-trial
#3
Ladan Kashani, Sophia Esalatmanesh, Farzaneh Eftekhari, Samrand Salimi, Tahereh Foroughifar, Farnaz Etesam, Hamideh Safiaghdam, Ehsan Moazen-Zadeh, Shahin Akhondzadeh
PURPOSE: Due to concerns regarding the side effects of hormone therapy, many studies have focused on the development of non-hormonal agents for treatment of hot flashes. The aim of this study was to evaluate the efficacy and safety of saffron (stigma of Crocus sativus) in treatment of major depressive disorder associated with post-menopausal hot flashes. METHODS: Sixty women with post-menopausal hot flashes participated in this study. The patients randomly received either saffron (30 mg/day, 15 mg twice per day) or placebo for 6 weeks...
January 13, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29332196/bioelectronic-modulation-of-carotid-sinus-nerve-activity-in-the-rat-a-potential-therapeutic-approach-for-type-2-diabetes
#4
Joana F Sacramento, Daniel J Chew, Bernardete F Melo, Matteo Donegá, Wesley Dopson, Maria P Guarino, Alison Robinson, Jesus Prieto-Lloret, Sonal Patel, Bradley J Holinski, Nishan Ramnarain, Victor Pikov, Kristoffer Famm, Silvia V Conde
AIMS/HYPOTHESIS: A new class of treatments termed bioelectronic medicines are now emerging that aim to target individual nerve fibres or specific brain circuits in pathological conditions to repair lost function and reinstate a healthy balance. Carotid sinus nerve (CSN) denervation has been shown to improve glucose homeostasis in insulin-resistant and glucose-intolerant rats; however, these positive effects from surgery appear to diminish over time and are heavily caveated by the severe adverse effects associated with permanent loss of chemosensory function...
January 14, 2018: Diabetologia
https://www.readbyqxmd.com/read/29332193/melanogenesis-inhibitory-activity-of-components-from-salam-leaf-syzygium-polyanthum-extract
#5
Andriyana Setyawati, Kae Hirabayashi, Kosei Yamauchi, Hiroyuki Hattori, Tohru Mitsunaga, Irmanida Batubara, Rudi Heryanto, Hiroshi Hashimoto, Mitsuyuki Hotta
In order to identify a novel whitening agent, the methanol extract of S. polyanthum leaf was focused on by the screening test using nine Indonesian medicinal plants for the inhibition of melanogenesis and tyrosinase activity in B16 melanoma cells. Three novel compounds [(1) 1-(2,3,5-trihydroxy-4-methylphenyl)hexane-1-one, (2) 1-(2,3,5-trihydroxy methylphenyl)octane-1-one, and (3) (4E)-1-(2,3,5-trihydroxy-4-methylphenyl)decan-1-one and one known compound [(4) 1-(2,3,5-trihydroxy-4-methylphenyl)decan-1-one were isolated from the methanol extract...
January 13, 2018: Journal of Natural Medicines
https://www.readbyqxmd.com/read/29332154/the-influence-of-systemically-or-locally-administered-mesenchymal-stem-cells-on-tissue-repair-in-a-rat-oral-implantation-model
#6
Miya Kanazawa, Ikiru Atsuta, Yasunori Ayukawa, Takayoshi Yamaza, Ryosuke Kondo, Yuri Matsuura, Kiyoshi Koyano
BACKGROUND: Multipotent mesenchymal stem cells (MSCs) are used clinically in regenerative medicine. Our previous report showed systemically injected MSCs improved peri-implant sealing and accelerated tissue healing. However, the risks of systemic MSC administration, including lung embolism, must be considered; therefore, their local application must be assessed for clinical safety and efficacy. We investigated differences in treatment effect between local and systemic MSC application using a rat oral implantation model...
January 13, 2018: International Journal of Implant Dentistry
https://www.readbyqxmd.com/read/29332145/the-experiences-and-beliefs-of-older-people-in-scottish-very-sheltered-housing-about-using-multi-compartment-compliance-aids
#7
Derek Stewart, Kathrine Gibson Smith, Joan MacLeod, Alison Strath, Vibhu Paudyal, Katrina Forbes-McKay, Scott Cunningham, Katie MacLure
Background Multi-compartment compliance aids (MCAs) are promoted as a potential solution to medicines non-adherence despite the absence of high quality evidence of effectiveness of MCA use impacting medicines adherence or any clinical outcomes. Furthermore, there is a lack of qualitative research which focuses on the perspectives of older people receiving MCAs. Objectives To describe experiences and beliefs surrounding very sheltered housing (VSH) residents' use of MCAs with emphasis on issues of personalisation, reablement, shared decision-making, independence and support...
January 13, 2018: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/29332110/association-of-psychological-stress-with-skin-symptoms-among-medical-students
#8
Ghada A Bin Saif, Hala M Alotaibi, Abdullateef A Alzolibani, Noor A Almodihesh, Hamad F Albraidi, Najed M Alotaibi, Gil Yosipovitch
To evaluate the association between psychological stress and skin symptoms among medical students.  Methods: A cross-sectional study was carried out between January and June 2015. Electronic survey consists of Perceived Stress Questionnaire (PSQ) and Self-Reported Skin Complaints Questionnaire were distributed to all 1435 undergraduate students at College of Medicine, King Saud University (KSU), Riyadh, Saudi Arabia. Results: Final analysis was performed on data from 529 (36.9%) students. Students were divided into three groups: least stressed students, n=135, PSQ index less than 0...
January 2018: Saudi Medical Journal
https://www.readbyqxmd.com/read/29332103/proteomic-effects-of-wet-cupping-al-hijamah
#9
Amer A Almaiman
Wet cupping (Al-hijamah) is a therapeutic technique practiced worldwide as a part of the Unani system of medicine. It involves bloodletting from acupoints on a patient's skin to produce a therapeutic outcome. A thorough review of research articles on wet cupping with relevance to proteomics field that are indexed by Google Scholar, PubMed, and/or Science Direct databases was performed. Eight original research articles were summarized in this paper. Overall, wet cupping did not have a significant effect on C-reactive protein, Hsp-27, sister chromatid exchanges, and cell replication index...
January 2018: Saudi Medical Journal
https://www.readbyqxmd.com/read/29332034/microhemodynamic-indices-to-evaluate-the-effectiveness-of-herbal-medicine-in-diabetes-a-comparison-between-alpha-mangostin-and-curcumin-in-the-retina-of-type-2-diabetic-rats
#10
Amporn Jariyapongskul, Chonticha Areebambud, Niimi Hideyuki
OBJECTIVE: This study was aimed to develop microhemodynamic indices to evaluate the effectiveness of herbal medicine in diabetic tissues. METHODS: Male Sprague-Dawley rats were divided into four groups: normal control rats (Control), type 2 diabetic rats without (DM2) and with supplementation of alpha mangostin (DM2-MG) or curcumin (DM2-CUR). Alpha-mangostin or curcumin (200 mg/kg BW) were fed followed by i.p. injection of streptozotocin (STZ). Mean arterial pressure (MAP) and retinal blood flow (RBF) were measured and retinal flow resistance (RFR) was calculated...
January 10, 2018: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/29332026/medicinal-plant-materials-in-the-treatment-of-anxiety-disorders-neurobiological-aspects
#11
Miłosz Jan Gołyszny, Ewa Obuchowicz
Context • Pathological anxiety, which affects approximately one-third of the world population, is an inadequate, irrational reaction of an organism to the environment and to a potential threat. Despite advancements in pharmacotherapy for anxiety disorders, further studies are still necessary to search for new substances possessing the desired anxiolytic effects, with as few unwanted effects as possible. Objective • This study intended to examine the characteristics of medicinal plant materials that exhibit anxiolytic properties, with a special emphasis on the mechanisms of action of their active ingredients on the systems involved in the pathophysiology of anxiety...
January 15, 2018: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/29332025/prolegomena-to-a-true-integrative-medical-paradigm
#12
Babak Daneshfard, Mohammad Reza Sanaye, Majid Nimrouzi
When a paradigm starts to show signs of failure to cope with significant questions in any basic/applied branch of human knowledge, there come on the scene those who have perused the related literature enough to either answer those major questions according to the established paradigm or proffer a (wholly) new way of looking at things. In the latter case, the history of science tells us, a paradigm shift takes place. Modern medicine cannot be proven to be totally disconnected from its traditional roots. Where traditional medicine came to give its place to present-day conventional medicine, a number of humanistic aspects of healing, in addition to some axioms of old wisdom, were actually lost...
January 15, 2018: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/29332022/comparative-antitussive-effects-of-medicinal-plants-and-their-constituents
#13
Saeideh Saadat, Farzaneh Shakeri, Mohammad Hossein Boskabady
Context • The cough is a protective reflex, with 2 types, one being more sensitive to mechanical stimulation and the other to chemical stimulation, such as sulfur dioxide, ammonia, citric acid, and capsaicin. Some evidence is available that suppressant therapy is most effective when used for the short-term reduction of coughing. Today, use of herbal drugs is increasing all over the world for various ailments, including to provide antitussive activity. Objective • The study intended to review the antitussive effects of various extracts, some fractions, and some constituents of the studied medicinal plants...
January 15, 2018: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/29332021/the-effects-of-reflexology-on-fatigue-and-anxiety-in-patients-with-multiple-sclerosis
#14
Afitap Ozdelikara, Seval Agcadiken Alkan
Context • Multiple sclerosis (MS) is an inflammatory, demyelinating disease of the central nervous system. In addition to the progressive nature of the disease, devastating symptoms adversely affect the patient's daily life and future expectations. This situation leads patients to seek complementary and alternative treatments. Objectives • This study was conducted to determine the effects of reflexology on fatigue severity and anxiety in patients with MS. Design • The research was a quasi-experimental, pretest-posttest design...
January 15, 2018: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/29332008/leg-stereotypy-syndrome-phenomenology-and-prevalence
#15
Mitesh Lotia, Michele K York, Adriana M Strutt, Joseph Jankovic
OBJECTIVES: To describe the phenomenology and prevalence of leg stereotypy syndrome (LSS), characterised chiefly by repetitive, rhythmical, stereotypic leg movement, especially when sitting. METHODS: We sought to characterise LSS in two groups of subjects: (1) general population (GP) group, defined as individuals accompanying patients during their visits to Baylor College of Medicine Parkinson's Disease Center and Movement Disorders Clinic who are not genetically related to the patients; and (2) movement disorders (MD) group, composed of consecutive patients with diagnoses of restless legs syndrome, Parkinson's disease, Tourette syndrome and tardive dyskinesia...
January 13, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29332007/impacts-of-canada-s-minimum-age-for-tobacco-sales-mats-laws-on-youth-smoking-behaviour-2000-2014
#16
Russell Clarence Callaghan, Marcos Sanches, Jodi Gatley, James K Cunningham, Michael Oliver Chaiton, Robert Schwartz, Susan Bondy, Claire Benny
BACKGROUND: Recently, the US Institute of Medicine has proposed that raising the minimum age for tobacco purchasing/sales to 21 years would likely lead to reductions in smoking behavior among young people. Surprisingly few studies, however, have assessed the potential impacts of minimum-age tobacco restrictions on youth smoking. OBJECTIVE: To estimate the impacts of Canadian minimum age for tobacco sales (MATS) laws on youth smoking behaviour. DESIGN: A regression-discontinuity design, using seven merged cycles of the Canadian Community Health Survey, 2000-2014...
January 13, 2018: Tobacco Control
https://www.readbyqxmd.com/read/29331970/is-there-a-social-gradient-of-sarcopenia-a-meta-analysis-and-systematic-review-protocol
#17
Darci Green, Gustavo Duque, Nick Fredman, Aoun Rizvi, Sharon Lee Brennan-Olsen
INTRODUCTION: Sarcopenia (or loss of muscle mass and function) is a relatively new area within the field of musculoskeletal research and medicine. Investigating whether there is a social gradient, including occupation type and income level, of sarcopenia, as observed for other diseases, will contribute significantly to the limited evidence base for this disease. This new information may inform the prevention and management of sarcopenia and widen the evidence base to support existing and future health campaigns...
January 13, 2018: BMJ Open
https://www.readbyqxmd.com/read/29331950/construction-of-an-evaluation-index-system-for-determining-the-academic-impact-of-military-medical-scholars
#18
Xuan Li, J Y Hao
INTRODUCTION: Academic papers are an essential manner for describing new ideas and consolidating existing concepts in the field of military medicine. The academic impact of military medical publications reflects the extent and depth of recognition, acceptance and utilisation of the concepts transmitted in these publications. The aim of this research was to construct an evaluation index system suitable for evaluating the academic influence of scholars in the field of military medicine...
January 13, 2018: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/29331949/bibliometric-analysis-of-military-trauma-publications-2000-2016
#19
Mark L Vickers, C P Coorey, G J Milinovich, L Eriksson, M Assoum, M C Reade
INTRODUCTION: Bibliometric tools can be used to identify the authors, topics and research institutions that have made the greatest impact in a field of medicine. The aim of this research was to analyse military trauma publications over the last 16 years of armed conflict in order to highlight the most important lessons that have translated into civilian practice and military doctrine as well as identify emerging areas of importance. METHODS: A systematic search of research published between January 2000 and December 2016 was conducted using the Thompson Reuters Web of Science database...
January 13, 2018: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/29331903/rapid-structure-prediction-by-hplc-esi-msn-of-twenty-five-polyoxypregnane-tetraglycosides-from-dregea-sinensis-with-nmr-confirmation-of-eight-structures
#20
Juan Song, Rongji Dai, Yulin Deng, Fang Lv
Dregea sinensis Hemsl is an important herbal medicine in the Dai nationality of China. Its prominent clinical application has generated interest in the polyoxypregnane glycosides of the plant. This paper describes an extension of previous research on the polyoxypregnane di- and triglycosides of D. sinensis, aiming at identifying related tetraglycosides. On the basis of HPLC-ESI-MSn analysis in positive mode, twenty-five previously undescribed polyoxypregnane tetraglycosides were characterized (regarding molecular masses and fragmentation in MSn) from an ethyl acetate fraction that was not previously investigated...
January 11, 2018: Phytochemistry
keyword
keyword
9012
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"