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https://www.readbyqxmd.com/read/27603220/putative-functions-of-tissue-kallikrein-related-peptidases-in-vaginal-fluid
#1
REVIEW
Carla M J Muytjens, Stella K Vasiliou, Katerina Oikonomopoulou, Ioannis Prassas, Eleftherios P Diamandis
Cervical-vaginal fluid (CVF) is a complex biological fluid that hydrates the mucosa of the lower female reproductive system. In-depth proteomic and biochemical studies on CVF have revealed that it contains large amounts of endogenous proteases and protease inhibitors, including an abundance of several members of the tissue kallikrein-related peptidase (KLK) family. Despite their ubiquitous presence in human tissues and fluids, KLK expression levels vary considerably, with maximum expression observed in reproduction-related tissues and fluids...
October 2016: Nature Reviews. Urology
https://www.readbyqxmd.com/read/27356796/-the-relationship-between-group-b-streptococcus-genital-infection-and-premature-rupture-of-membrane
#2
J J Yan, M Gong, J Zhang, C B Zhu
OBJECTIVE: To investigate the relationship between the group B streptococcal (GBS) genital infection of the pregnant women and premature rupture of membrane (PROM). METHODS: Five hundred and eighty seven cases in our hospital maternity clinic or hospital delivery of pregnant women were enrolled from October 2014 to December 2014, including 189 cases of pregnant women with PROM as the observation group and 398 cases of pregnant women without PROM as a control group...
June 21, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/27142383/a-case-of-uterine-torsion-concurrent-with-a-ruptured-ovarian-endometrial-cyst
#3
Aya Hashimoto, Junko Takahama, Naoya Harada, Shinsaku Maeda, Hiroshi Anai, Akio Fukusumi, Shunsuke Imai, Kimihiko Kichikawa
The patient was a 54-year-old female presented with severe abdominal swelling and intermittent pain. On emergent CT, massive ascites with thickened peritoneum and intra-pelvic cystic mass approximately 20 cm in diameter were observed. The cyst wall showed redundant irregular shape. The uterus was enlarged with intramural mass located at its right anterior fundus. MRI showed this pelvic cyst as high intensity on T1-weighted images, so that it was suspected as an endometrial cyst. The operation revealed the rupture of endometrial cyst and the uterine torsion of 180° around the long axis...
September 2016: Abdominal Radiology
https://www.readbyqxmd.com/read/27127435/bacterial-endocarditis-caused-by-lactobacillus-acidophilus-leading-to-rupture-of-sinus-of-valsalva-aneurysm
#4
Carlos Omar Encarnacion, Austin Mitchell Loranger, A G Bharatkumar, G Hossein Almassi
Lactobacillus acidophilus rarely causes bacterial endocarditis, because it usually resides in the mucosa of the vagina, gastrointestinal tract, and oropharynx. Moreover, sinus of Valsalva aneurysms are rare cardiac anomalies, either acquired or congenital. We present the case of a middle-aged man whose bacterial endocarditis, caused by Lactobacillus acidophilus, led to an aneurysmal rupture of the sinus of Valsalva into the right ventricular outflow tract. The patient underwent successful surgical repair, despite numerous complications and sequelae...
April 2016: Texas Heart Institute Journal
https://www.readbyqxmd.com/read/27106195/predictors-of-outcomes-of-non-elective-cervical-cerclages
#5
Elham M Jalal, Felipe Moretti, Andree Gruslin
BACKGROUND: Non-elective cervical cerclages are associated with significant perinatal complications. There is scant available information about what the predictors of these outcomes are, thus making counselling difficult. OBJECTIVE: To identify which factors predict delivery at or beyond 28, 34, and 37 weeks' gestation in women with emergency/rescue cervical cerclage. METHODS: We conducted a retrospective cohort study of nonelective cerclages over 10 years in our centre...
March 2016: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/27047692/antibiotic-prophylaxis-for-gynecologic-procedures-prior-to-and-during-the-utilization-of-assisted-reproductive-technologies-a-systematic-review
#6
REVIEW
Nigel Pereira, Anne P Hutchinson, Jovana P Lekovich, Elie Hobeika, Rony T Elias
The use of assisted reproductive technologies (ART) has increased steadily. There has been a corresponding increase in the number of ART-related procedures such as hysterosalpingography (HSG), saline infusion sonography (SIS), hysteroscopy, laparoscopy, oocyte retrieval, and embryo transfer (ET). While performing these procedures, the abdomen, upper vagina, and endocervix are breached, leading to the possibility of seeding pelvic structures with microorganisms. Antibiotic prophylaxis is therefore important to prevent or treat any procedure-related infections...
2016: Journal of Pathogens
https://www.readbyqxmd.com/read/27039249/pregnancy-loss-french-clinical-practice-guidelines
#7
EDITORIAL
C Huchon, X Deffieux, G Beucher, P Capmas, X Carcopino, N Costedoat-Chalumeau, A Delabaere, V Gallot, E Iraola, V Lavoue, G Legendre, V Lejeune-Saada, J Leveque, S Nedellec, J Nizard, T Quibel, D Subtil, F Vialard, D Lemery
In intrauterine pregnancies of uncertain viability with a gestational sac without a yolk sac (with a mean of three orthogonal transvaginal ultrasound measurements <25mm), the suspected pregnancy loss should only be confirmed after a follow-up scan at least 14 days later shows no embryo with cardiac activity (Grade C). In intrauterine pregnancies of uncertain viability with an embryo <7mm on transvaginal ultrasound, the suspected pregnancy loss should only be confirmed after a follow-up scan at least 7 days later (Grade C)...
June 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/26968288/maternal-outcome-of-early-intervention-in-women-with-prom-at-term-37-weeks-or-more
#8
Sajida Alias Sahibzadi Hingoro, Naushaba Rizwan, Roshan Ara Qazi
Pre-labour rupture of membranes (PROM) is associated with complications as increase in the rate of induction of labour, foetal distress, foetal and maternal infection, and caesarean section. The objective of this case series was to determine the maternal outcome of early intervention with prostaglandin E2 in women with PROM at term in a Tertiary Care Hospital. The study period was six months from 2nd July 2014 to 1st January 2015. A total of 183 women with spontaneous PROM were selected. Detailed history was taken and clinical examination was performed...
March 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/26784330/vaginal-versus-obstetric-infection-escherichia-coli-isolates-among-pregnant-women-antimicrobial-resistance-and-genetic-virulence-profile
#9
Emma Sáez-López, Elisabet Guiral, Dietmar Fernández-Orth, Sonia Villanueva, Anna Goncé, Marta López, Irene Teixidó, Anna Pericot, Francesc Figueras, Montse Palacio, Teresa Cobo, Jordi Bosch, Sara M Soto
Vaginal Escherichia coli colonization is related to obstetric infections and the consequent development of infections in newborns. Ampicillin resistance among E. coli strains is increasing, which is the main choice for treating empirically many obstetric and neonatal infections. Vaginal E. coli strains are very similar to extraintestinal pathogenic E. coli with regards to the virulence factors and the belonging to phylogroup B2. We studied the antimicrobial resistance and the genetic virulence profile of 82 E...
2016: PloS One
https://www.readbyqxmd.com/read/26765160/the-effect-of-warm-compress-bistage-intervention-on-the-rate-of-episiotomy-perineal-trauma-and-postpartum-pain-intensity-in-primiparous-women-with-delayed-valsalva-maneuver-referring-to-the-selected-hospitals-of-shiraz-university-of-medical-sciences-in-2012
#10
Marzieh Akbarzadeh, Faride Vaziri, Mahnaz Farahmand, Zahra Masoudi, Sedigheh Amooee, Najaf Zare
BACKGROUND: Genital trauma during vaginal delivery may result from episiotomy, spontaneous perineal tears (perineum, vagina), or both. In 2012, this study aimed to investigate the effect of warm compress bistage intervention on the rate of episiotomy, perineal trauma, and postpartum pain intensity in the primiparous woman with delayed Valsalva maneuver. METHODS: In this randomized clinical trial, which was performed in hospitals in Shiraz, Iran, in 2012-2013, 150 women were randomly divided into 2 groups: 1 intervention and 1 control...
February 2016: Advances in Skin & Wound Care
https://www.readbyqxmd.com/read/26723194/prolonged-latency-of-preterm-premature-rupture-of-membranes-and-risk-of-neonatal-sepsis
#11
Daphnie Drassinower, Alexander M Friedman, Sarah G Običan, Heather Levin, Cynthia Gyamfi-Bannerman
BACKGROUND: Preterm premature rupture of membranes (PPROM) is associated with inflammation and infection, and it may involve the loss of a barrier to ascending infection from the vagina, and it is possible that prolonged PPROM could be an independent risk factor for neonatal sepsis. OBJECTIVE: The objective of the study was to determine whether prolonged latency after PPROM is associated with an increased risk of neonatal sepsis. STUDY DESIGN: This secondary analysis of the randomized controlled trial of magnesium sulfate for the prevention of cerebral palsy evaluated whether the time interval between diagnosis of PPROM and delivery was associated with an increased risk of neonatal sepsis...
June 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/26644969/persistent-microbial-dysbiosis-in-preterm-premature-rupture-of-membranes-from-onset-until-delivery
#12
Elizabeth A Baldwin, Marina Walther-Antonio, Allison M MacLean, Daryl M Gohl, Kenneth B Beckman, Jun Chen, Bryan White, Douglas J Creedon, Nicholas Chia
Background. Preterm Premature Rupture of Membranes (PPROM) is a major leading cause of preterm births. While the cause for PPROM remains unidentified, it is anticipated to be due to subclinical infection, since a large proportion of PPROM patients display signs of chorioamnionitis. Since subclinical infections can be facilitated by dysbiosis, our goal was to characterize the vaginal microbiome and amniotic fluid discharge upon PPROM, through latency antibiotic treatment, and until delivery, to detect the presence of pathogens, microbiota alteration, and microbial response to treatment...
2015: PeerJ
https://www.readbyqxmd.com/read/26557398/successful-delivery-of-twin-pregnancy-in-class-u3b-c2-v1-uterus-by-bilateral-caesarean-section-after-spontaneous-conception
#13
Yasmine El-Masry, Ahmed M E Ossman, Mohammed El-Namoury, Sameh Sarsik
A case of a 19-year-old female with class U3b/C2/V1 uterus conceived a twin pregnancy with a fetus in each horn after spontaneous conception. She referred to our department with presentation of premature rupture of membranes, with a history of cesarean delivery of a single full term living fetus a year and a half before this delivery. Examination revealed two completely separate uterine horns with a fetus in each horn, two distinct externally rounded cervices, and a single vagina with a short nonobstructing vaginal septum in the upper part of the vagina...
2015: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/26153188/culture-and-real-time-pcr-based-maternal-screening-and-antibiotic-susceptibility-for-group-b-streptococcus-an-iranian-experience
#14
Gholamreza Goudarzi, Masoumeh Ghafarzadeh, Pegah Shakib, Khatereh Anbari
INTRODUCTION: Vertical Transmission of group B streptococcus (GBS) from a vagina colonized mother to her infant upon rupture of membranes (ROM) or after the onset of labor can cause life-threatening infections in newborn. Although intrapartum antibiotic prophylaxis (IAP) can significantly decrease neonatal GBS diseases, this issue has potentiated the emergence of antibiotic resistance strains. Our study examined the colonization rate of GBS using real-time PCR and culture methods, and trends in antibiotic resistance of GBS isolates obtained from pregnant women in Khorramabad, Iran...
2015: Global Journal of Health Science
https://www.readbyqxmd.com/read/26151997/female-genital-mutilation-cutting-an-update
#15
REVIEW
A A Rouzi, F Alturki
Female genital mutilation/cutting (FGM/C) is a cultural practice involving several types of external female genitalia cutting. FGM/C is known to occur in all parts of the world but is most prevalent in 28 countries in Africa and the Middle East and among immigrant communities in Europe, Australia, New Zealand, Canada, and the United States. Studies of FGM/C suffer from many methodological problems including inadequate analysis and an unclear reporting of results. The evidence to link FGM/C to infertility is weak...
2015: Clinical and Experimental Obstetrics & Gynecology
https://www.readbyqxmd.com/read/26063072/imaging-of-body-packing-errors-and-medico-legal-issues
#16
REVIEW
Alfonso Reginelli, Anna Russo, Fabrizio Urraro, Duilia Maresca, Ciro Martiniello, Alfredo D'Andrea, Luca Brunese, Antonio Pinto
Body packing is the ingestion or insertion in the human body of packed illicit substances. Over the last 20 years, drug smuggling has increased global and new means of transport of narcotics have emerged. Among these, the most frequent one is the gastrointestinal tract: from mouth to anus, vagina, and ears. Cocaine is one of the most traded drugs, followed by heroin. Condoms, latex gloves, and balloons are typically used as drug packets for retention in the body. There are different radiologic modalities to detect illicit drugs in body packing: Plain radiography, computed tomography (CT), ultrasound, and magnetic resonance...
October 2015: Abdominal Imaging
https://www.readbyqxmd.com/read/26029118/human-cervicovaginal-fluid-biomarkers-to-predict-term-and-preterm-labor
#17
REVIEW
Yujing J Heng, Stella Liong, Michael Permezel, Gregory E Rice, Megan K W Di Quinzio, Harry M Georgiou
Preterm birth (PTB; birth before 37 completed weeks of gestation) remains the major cause of neonatal morbidity and mortality. The current generation of biomarkers predictive of PTB have limited utility. In pregnancy, the human cervicovaginal fluid (CVF) proteome is a reflection of the local biochemical milieu and is influenced by the physical changes occurring in the vagina, cervix and adjacent overlying fetal membranes. Term and preterm labor (PTL) share common pathways of cervical ripening, myometrial activation and fetal membranes rupture leading to birth...
2015: Frontiers in Physiology
https://www.readbyqxmd.com/read/25972201/altered-gene-expression-profile-in-ovarian-follicle-in-rats-treated-with-indomethacin-and-ru486
#18
Kenjiro Tsubota, Masayuki Kanki, Takahisa Noto, Shunji Nakatsuji, Yuji Oishi, Masahiro Matsumoto, Hiroyuki Nakayama
It is well-known that indomethacin (the cyclooxygenase 1 & 2 inhibitor) and RU486 (or mifepristone, the progesterone receptor antagonist) block follicular rupture in rats. To characterize genetic alterations in unruptured follicles, gene expression profiles in ovarian follicle were analyzed in indomethacin- and RU486-treated female Sprague-Dawley rats. Ovaries are collected at 22:00 on the proestrus day and 10:00 on the following estrus day after a single dose of indomethacin and RU486. Histopathologically, changes depicting responses to LH surge were observed in ovaries, uteri and vagina...
June 2015: Journal of Toxicological Sciences
https://www.readbyqxmd.com/read/25926958/assessing-the-prevalence-of-bacterial-vaginosis-among-infertile-women-of-qom-city
#19
Mahdieh Ghiasi, Hoda Fazaeli, Naser Kalhor, Mohsen Sheykh-Hasan, Reza Tabatabaei-Qomi
BACKGROUND AND OBJECTIVES: Bacterial vaginosis (BV) is a common disorder which happens when the balance of bacterial flora in vagina is disrupted by a shift in concentration of lactobacillus and pathogenic bacteria.It has significant sequelae including increased rates of late miscarriage when diagnosed in early pregnancy, premature rupture of the membranes, endometritis, preterm labour and delivery and tubal factor infertility. So it seems to be necessary to evaluate the prevalence of BV among women with primary infertility...
December 2014: Iranian Journal of Microbiology
https://www.readbyqxmd.com/read/25923242/streptococcus-agalactiae-in-pregnancies-complicated-by-preterm-prelabor-rupture-of-membranes
#20
Ivana Musilova, Lenka Pliskova, Radka Kutova, Bo Jacobsson, Pavla Paterova, Marian Kacerovsky
OBJECTIVE: The main aim of this study was to evaluate the presence of Streptococcus agalactiae (S. agalactiae) in the vagina and the amniotic fluid in pregnancies complicated by preterm prelabor rupture of membranes (PPROM). The next aim was to evaluate the incidence of S. agalactiae early onset sepsis in newborns from PPROM pregnancies, with respect to the presence of S. agalactiae in the vagina and the amniotic fluid. METHODS: Singleton gestations with PPROM between 24 + 0 and 36 + 6 were included...
2016: Journal of Maternal-fetal & Neonatal Medicine
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