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https://www.readbyqxmd.com/read/29761706/genotoxic-and-cytotoxic-effects-of-haas-appliance-in-exfoliated-buccal-mucosa-cells-during-orthodontic-treatment
#1
Arthur S Cunha, Willian Orlando Castillo, Catarina Satie Takahashi, Erika Calvano Küchler, Raquel Assed Bezerra Segato, Léa Assed Bezerra da Silva, Fábio Lourenço Romano, Mírian Aiko Nakane Matsumoto, Paulo Nelson-Filho
OBJECTIVES: To evaluate the genotoxic and cytotoxic effects of Haas appliances through micronuclei test and cytogenetic damage analysis in buccal mucosa epithelial cells of patients undergoing orthodontic treatment. MATERIALS AND METHODS: Twenty-eight patients, 6-12 years of age and of both genders, who required a Haas appliance for the correction of a posterior crossbite were included. Epithelial cells from the mucosa were collected by gently scraping the inside of both the right and left cheeks...
May 15, 2018: Angle Orthodontist
https://www.readbyqxmd.com/read/29752891/effectiveness-and-tolerability-of-direct-acting-antivirals-for-chronic-hepatitis-c-patients-in-a-southern-state-of-brazil
#2
Vinicius Lins Ferreira, Helena Hiemisch Lobo Borba, Astrid Wiens, Maria Lucia Alves Pedroso, Vanessa Ferreira de Camargo Radunz, Cláudia Alexandra Pontes Ivantes, Aline Satie Oba Kuniyoshi, Roberto Pontarolo
BACKGROUND: This study aimed to evaluate the clinical effectiveness in terms of sustained virological response (SVR) and tolerability of available second generation direct-acting antivirals (DAAs) in Brazilian patients. METHODS: This was a retrospective observational study conducted in six centers in Southern Brazil. The sample comprised adult patients who were chronically infected with hepatitis C virus (HCV), regardless of virus genotype, fibrosis stage, or prior treatment...
May 9, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29752305/white-matter-integrity-and-processing-speed-in-sickle-cell-anemia
#3
Hanne Stotesbury, Fenella J Kirkham, Melanie Kölbel, Philippa Balfour, Jonathan D Clayden, Sati Sahota, Simrat Sakaria, Dawn E Saunders, Jo Howard, Rachel Kesse-Adu, Baba Inusa, Maria Pelidis, Subarna Chakravorty, David C Rees, Moji Awogbade, Olu Wilkey, Mark Layton, Christopher A Clark, Jamie M Kawadler
OBJECTIVE: The purpose of this retrospective cross-sectional study was to investigate whether changes in white matter integrity are related to slower processing speed in sickle cell anemia. METHODS: Thirty-seven patients with silent cerebral infarction, 46 patients with normal MRI, and 32 sibling controls (age range 8-37 years) underwent cognitive assessment using the Wechsler scales and 3-tesla MRI. Tract-based spatial statistics analyses of diffusion tensor imaging (DTI) and neurite orientation dispersion and density imaging (NODDI) parameters were performed...
May 11, 2018: Neurology
https://www.readbyqxmd.com/read/29751431/depositional-history-of-polychlorinated-biphenyls-pcbs-organochlorine-pesticides-ocps-and-polycyclic-aromatic-hydrocarbons-pahs-in-an-amazon-estuary-during-the-last-century
#4
Patrícia A Neves, Fernanda I Colabuono, Paulo A L Ferreira, Silvia K Kawakami, Satie Taniguchi, Rubens C L Figueira, Michel M Mahiques, Rosalinda C Montone, Márcia C Bícego
The sources and depositional history of OCPs (organochlorine pesticides), PCBs (polychlorinated biphenyls) and PAHs (polycyclic aromatic hydrocarbons) over the last 100years were determined in two sediment cores collected in the Amazon region. It was possible to distinguish two depositional periods along the cores. The first period occurred before extensive anthropogenic effects were registered in the sediments. During this time interval, the concentrations of all OCPs and PCBs were below the detection limits (DL), and the PAH concentrations were low and essentially constant (58...
February 15, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29724768/identification-of-chronic-active-multiple-sclerosis-lesions-on-3t-mri
#5
M Absinta, P Sati, A Fechner, M K Schindler, G Nair, D S Reich
BACKGROUND AND PURPOSE: MR imaging-pathologic studies have reported that paramagnetic rims on 7T susceptibility-based MR imaging identify, in vivo, the subset of MS lesions with compartmentalized inflammation at the lesion edge and associated remyelination failure. Here, we assessed the reliability of detecting these rims on high-resolution 3T phase images. MATERIALS AND METHODS: High-resolution T2* and phase MR imaging was collected in 20 patients with MS at 3T (3D segmented EPI, 0...
May 3, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29720516/seminal-siv-in-chronically-infected-cynomolgus-macaques-is-dominated-by-virus-originating-from-multiple-genital-organs
#6
Laurent Houzet, Marcos Pérez-Losada, Giulia Matusali, Claire Deleage, Nathalie Dereuddre-Bosquet, Anne-Pascale Satie, Florence Aubry, Emmanuelle Becker, Bernard Jégou, Roger Le Grand, Brandon F Keele, Keith A Crandall, Nathalie Dejucq-Rainsford
The sexual transmission of viruses is responsible for the spread of multiple infectious diseases. Although the HIV/AIDS pandemic remains fueled by sexual contacts with infected semen, the origin of virus in semen is still unknown. In a substantial number of HIV- infected men, viral strains present in semen differ from the ones in blood, suggesting that HIV is locally produced within the genital tract. Such local production may be responsible for the persistence of HIV in semen despite effective antiretroviral therapy...
May 2, 2018: Journal of Virology
https://www.readbyqxmd.com/read/29709682/low-subcutaneous-adiposity-associates-with-higher-mortality-in-female-patients-with-cirrhosis
#7
Maryam Ebadi, Puneeta Tandon, Carlos Moctezuma-Velazquez, Sunita Ghosh, Vickie E Baracos, Vera C Mazurak, Aldo J Montano-Loza
BACKGROUND & AIMS: Two main body compartments, skeletal muscle and adipose tissue, exhibit independent functions. We aimed to explore the prognostic significance of skeletal muscle, visceral and subcutaneous adipose tissue, according to sex, in patients with cirrhosis assessed for liver transplantation (LT). METHODS: CT images taken at the 3rd. lumbar vertebra from 677 patients were quantified for three body composition indexes (cm2 /m2 ), visceral adipose tissue index (VATI), subcutaneous adipose tissue index (SATI), and skeletal muscle index (SMI)...
April 27, 2018: Journal of Hepatology
https://www.readbyqxmd.com/read/29708229/the-340b-benefit-program-why-we-should-care-about-both-its-intentions-and-outcomes
#8
EDITORIAL
Saty Satya-Murti
No abstract text is available yet for this article.
April 2018: Neurology. Clinical Practice
https://www.readbyqxmd.com/read/29708189/vestibular-evoked-myogenic-potential-testing-payment-policy-review-for-clinicians-and-payers
#9
REVIEW
Terry D Fife, Saty Satya-Murti, Robert F Burkard, John P Carey
Purpose of review: A recent American Academy of Neurology Evidence-Based Practice Guideline on vestibular myogenic evoked potential (VEMP) testing has described superior canal dehiscence syndrome (SCDS) and evaluated the merits of VEMP in its diagnosis. SCDS is an uncommon but now well-recognized cause of dizziness and auditory symptoms. This article familiarizes health care providers with this syndrome and the utility and shortcomings of VEMP as a diagnostic test and also explores payment policies for VEMP...
April 2018: Neurology. Clinical Practice
https://www.readbyqxmd.com/read/29705032/diagnosis-of-multiple-sclerosis-through-the-lens-of-ultra-high-field-mri
#10
Pascal Sati
The long-standing relationship between ultra-high-field (7 T) MRI and multiple sclerosis (MS) has brought new insights to our understanding of lesion evolution and its associated pathology. With the recent FDA approval of a commercially available scanner, 7 T MRI is finally entering the clinic with great expectations about its potential added value. By looking through the prism of MS diagnosis, this perspective article discusses current limitations and prospects of 7 T MRI techniques relevant to helping clinicians diagnose patients encountered in daily practice...
April 25, 2018: Journal of Magnetic Resonance
https://www.readbyqxmd.com/read/29692490/glued-intraocular-lens-with-descemet-stripping-endothelial-keratoplasty-in-aphakic-bullous-keratopathy
#11
Anita Mani, P S Moulick, Alok Sati, Sandeep Gupta
No abstract text is available yet for this article.
April 2018: Medical Journal, Armed Forces India
https://www.readbyqxmd.com/read/29688408/spatiotemporal-distribution-of-fibrinogen-in-marmoset-and-human-inflammatory-demyelination
#12
Nathanael J Lee, Seung-Kwon Ha, Pascal Sati, Martina Absinta, Nicholas J Luciano, Jennifer A Lefeuvre, Matthew K Schindler, Emily C Leibovitch, Jae Kyu Ryu, Mark A Petersen, Afonso C Silva, Steven Jacobson, Katerina Akassoglou, Daniel S Reich
Multiple sclerosis is an inflammatory demyelinating disease of the central nervous system. Although it has been extensively studied, the proximate trigger of the immune response remains uncertain. Experimental autoimmune encephalomyelitis in the common marmoset recapitulates many radiological and pathological features of focal multiple sclerosis lesions in the cerebral white matter, unlike traditional experimental autoimmune encephalomyelitis in rodents. This provides an opportunity to investigate how lesions form as well as the relative timing of factors involved in lesion pathogenesis, especially during early stages of the disease...
April 20, 2018: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/29659359/-pneumonia-associated-with-mechanical-ventilation-update-and-recommendations-inter-societies-sadi-sati
#13
Wanda Cornistein, Ángel M Colque, María Inés Staneloni, María Monserrat Lloria, Mónica Lares, Ana Laura González, Alejandro Fernández Garcés, Edith Carbone
Representatives of the Argentine Society of Infectious Diseases (SADI) and the Argentine Society of Intensive Therapy (SATI) worked together on the development of specific recommendations for the diagnosis, treatment and prevention of ventilator-associated pneumonia (VAP). The methodology used was the analysis of the literature published in the last 15 years, complemented with the opinion of experts and local data. This document aims to offer basic tools to optimize diagnosis based on clinical and microbiological criteria, orientation in empirical and targeted antibiotic schemes, news on posology and administration of antibiotics in critical patients and to promote effective measures to reduce the risk of VAP...
2018: Medicina
https://www.readbyqxmd.com/read/29564835/looking-for-broken-tad-boundaries-and-changes-on-dna-interactions-clinical-guide-to-3d-chromatin-change-analysis-in-complex-chromosomal-rearrangements-and-chromothripsis
#14
Kevin Yauy, Vincent Gatinois, Thomas Guignard, Satish Sati, Jacques Puechberty, Jean Baptiste Gaillard, Anouck Schneider, Franck Pellestor
Apparition of next-generation sequencing (NGS) was a breakthrough on knowledge of genome structure. Bioinformatic tools are a key point to analyze this huge amount of data from NGS and characterize the three-dimensional organization of chromosomes. This chapter describes usage of different browsers to explore publicly available online data and to search for possible 3D chromatin changes involved during complex chromosomal rearrangements as chromothripsis. Their pathogenic impact on clinical phenotype and gene misexpression can also be evaluated with annotated databases...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29559104/investigation-of-potential-risk-factors-associated-with-salmonella-presence-in-commercial-laying-hen-farms-in-nigeria
#15
Idowu Oluwabunmi Fagbamila, Marzia Mancin, Lisa Barco, Sati Samuel Ngulukun, Alexander Jambalang, Olawunmi Toyin Ajayi, Nancy Sati, Paulinus Emennaa, Paul Idoko Ankeli, Jakob Kwaga, Paul Ayuba Abdu, Junaidu Kabir, Jarlath Umoh, Antonia Ricci, Maryam Muhammad
BACKGROUND: In 2012/13, the Federal government of Nigeria approved the surveillance of salmonellae in commercial poultry farms with the aim of generating baseline data for the development of a control programme. That baseline provided an opportunity to investigate potential risk factors in commercial layer farms. METHODS: Five hundred and twenty-three farms were evaluated for the presence of Salmonella. Each farmer was interviewed through a structured questionnaire...
April 1, 2018: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/29524899/transplacental-transfer-of-persistent-organic-pollutants-in-la-plata-dolphins-pontoporia-blainvillei-cetartiodactyla-pontoporiidae
#16
Ana Paula Moreno Barbosa, Paula Méndez-Fernandez, Patrick Simões Dias, Marcos César Oliveira Santos, Satie Taniguchi, Rosalinda Carmela Montone
Persistent organic pollutants (POPs) accumulate in the fat tissue of living organisms and are found in relatively high concentrations in animals at the top of the food chain, such as dolphins. The ability of these compounds to interact with the endocrine system of marine mammals constitutes a risk for the reproduction and conservation of species. The La Plata dolphin, Pontoporia blainvillei, is exclusive to the southwestern Atlantic Ocean and is classified on the IUCN red list as a vulnerable species. Blubber, liver, kidney and muscle samples from four P...
August 1, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29503374/-agreement-in-the-responses-to-self-reported-and-proxy-reported-versions-of-qol-hc-a-new-quality-of-life-scale-for-patients-receiving-home-based-medical-care
#17
Hiroko Kamitani, Hiroyuki Umegaki, Kazushi Okamoto, Shigeru Kanda, Atsushi Asai, Takuya Shimojima, Hideki Nomura, Ayako Hattori, Takaya Kimata, Yusuke Suzuki, Hiroko Ohshima, Masafumi Kuzuya
AIM: We developed quality-of-life (QOL) scales for patients receiving home medical care. The objective of this study was to examine the agreement between the scores of the scales answered by patients and those answered by their proxy, as cognitive decline may interfere with one's ability to understand complex topics, such as the QOL. METHODS: Participants were pairs of patients receiving home medical care and their proxy. The patients were asked to complete self-reported QOL scales (QOL-HC), and their proxies were asked to complete proxy-reported versions of the QOL scales (QOL-HC for caregivers)...
2018: Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
https://www.readbyqxmd.com/read/29461359/the-relationship-between-expressed-emotion-and-the-probability-of-suicide-among-turkish-psychiatric-outpatients-a-descriptive-cross-sectional-survey
#18
Satı Demir
The purpose of this study is to examine expressed emotion and the relationship between expressed emotion and suicide probability in psychiatric outpatients (N = 350). Patients who did not receive support from anyone scored higher on the Level of Expressed Emotion (LEE) Scale than those who were supported by family, friends, or their physician provider. Scores by patients, who selected their spouse as a key person, scored higher on the LEE than those who chose one of their children. Spouses on the LEE were often depicted as being more intrusive, reactive, and intolerant when compared with their children...
April 2018: Family & Community Health
https://www.readbyqxmd.com/read/29459333/contamination-status-by-persistent-organic-pollutants-of-the-atlantic-spotted-dolphin-stenella-frontalis-at-the-metapopulation-level
#19
Paula Méndez-Fernandez, Satie Taniguchi, Marcos C O Santos, Irma Cascão, Sophie Quérouil, Vidal Martín, Marisa Tejedor, Manuel Carrillo, Carolina Rinaldi, Renato Rinaldi, Rosalinda C Montone
The Atlantic spotted dolphin (Stenella frontalis) is an endemic species of the tropical-temperate Atlantic Ocean with widespread distribution. Although this species has been the subject of a large number of studies throughout its range, it remains in the "data deficient" category of the International Union for Conservation of Nature (IUCN). Chemical pollution by persistent organic pollutants (POPs) has been listed as one of the major threats to this species, however, there is no information on a wide scale...
May 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29439120/improved-visualization-of-cortical-lesions-in-multiple-sclerosis-using-7t-mp2rage
#20
E S Beck, P Sati, V Sethi, T Kober, B Dewey, P Bhargava, G Nair, I C Cortese, D S Reich
BACKGROUND AND PURPOSE: Cortical lesions are common and often extensive in multiple sclerosis but are difficult to visualize by MRI, leaving important questions about their clinical implications and response to therapy unanswered. Our aim was to determine whether cortical lesions are better visualized using magnetization prepared 2 rapid acquisition gradient echoes (MP2RAGE) than T2*-weighted imaging on 7T MR imaging. MATERIALS AND METHODS: Brain MR imaging using T1-weighted MP2RAGE at 500-μm isotropic resolution, T2*-weighted gradient-echo, and T2*-weighted segmented echo-planar imaging sequences were collected for 13 patients with MS and 5 age-matched neurologically healthy controls on a 7T research system...
February 8, 2018: AJNR. American Journal of Neuroradiology
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