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https://www.readbyqxmd.com/read/29780117/a-case-of-gangliocytic-paraganglioma-with-carcinoma-of-the-ampulla-of-vater-a-case-report
#1
Masanari Sekine, Hiroyuki Miyatani, Keita Matsumoto, Hitomi Kashima, Yudai Koito, Takaya Miura, Yuko Takahashi, Rumiko Tsuboi, Takehiro Ishii, Junichi Fujiwara, Takeshi Uehara, Shunsuke Urayoshi, Kazuhito Yuhashi, Takeharu Asano, Noriyoshi Sagihara, Satohiro Matsumoto, Hirosato Mashima
The patient was a "73" -year-old woman who visited our hospital with the chief complaint of weight loss. Upper gastrointestinal endoscopy revealed an enlarged ampulla of Vater, and a biopsy led to a diagnosis of Group "4" gastric carcinoma; suspicious of adenocarcinoma. There were no findings suggesting invasion into the muscle layer of duodenum, despite tumor mass formation being observed in the sphincter of Oddi. We performed endoscopic papillectomy for both diagnostic and therapeutic purposes...
May 18, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29768645/outcomes-after-endoscopic-resection-of-large-laterally-spreading-lesions-of-the-papilla-and-conventional-ampullary-adenomas-are-equivalent
#2
Amir Klein, Zhengyan Qi, Farzan F Bahin, Halim Awadie, Dhruv Nayyar, Michael Ma, Rogier P Voermans, Stephen J Williams, Eric Lee, Michael J Bourke
BACKGROUND:  Endoscopic resection of ampullary adenomas is a safe and effective alternative to surgical resection. A subgroup of patients have large laterally spreading lesions of the papilla Vateri (LSL-P), which are frequently managed surgically. Data on endoscopic resection of LSL-P are limited and long-term outcomes are unknown. The aim of this study was to compare the outcomes of endoscopic resection of LSL-P with those of standard ampullary adenomas. METHODS:  A retrospective analysis of a prospectively collected and maintained database was conducted...
May 16, 2018: Endoscopy
https://www.readbyqxmd.com/read/29765558/the-fallopian-tube-microbiome-implications-for-reproductive-health
#3
Elise S Pelzer, Dana Willner, Melissa Buttini, Louise M Hafner, Christina Theodoropoulos, Flavia Huygens
Objective: There is a paucity of data characterizing the microbiota of the female upper genital tract, which controversially is described as a sterile site. We examine whether the fallopian tube harbours an endogenous microbial community. Design: This prospective study collected from women undergoing total hysterectomy or salpingectomy-oophorectomy. Setting: Private hospital gynaecology department. Patients: Fallopian tubes were collected from women diagnosed with benign disease or for prophylaxis...
April 20, 2018: Oncotarget
https://www.readbyqxmd.com/read/29753325/effects-of-pelvic-endometriosis-and-adenomyosis-on-ciliary-beat-frequency-and-muscular-contractions-in-the-human-fallopian-tube
#4
Wei Xia, Duo Zhang, Jing Ouyang, Yan Liang, Huiyu Zhang, Zhen Huang, Guiling Liang, Qian Zhu, Xiaoming Guan, Jian Zhang
BACKGROUND: Pelvic endometriosis (EM) and adenomyosis (AM) have different effects on the fallopian tube. This study aimed to assess the transport capability of the fallopian tube in women with pelvic EM or AM. METHODS: Twenty women with uterine leiomyoma (control group), 20 with adenomyosis without pelvic EM (AM group) and 35 with pelvic EM without AM (EM group) were included. EM cases were further divided into the tubal EM and non-tubal EM subgroups. Ciliary beat frequency (CBF), percentage of ciliated cells, and smooth muscle contraction were measured...
May 12, 2018: Reproductive Biology and Endocrinology: RB&E
https://www.readbyqxmd.com/read/29751229/endoscopy-mediated-intratubal-insemination-in-the-cow-development-of-a-novel-minimally-invasive-ai-technique
#5
Karina Radefeld, Sophie Papp, Vitezslav Havlicek, Jane M Morrell, Gottfried Brem, Urban Besenfelder
Conventionally inseminated spermatozoa suffer a dramatic reduction in numbers during their long journey until fertilization. In addition sperm survival seems to be strongly affected by the reconstitution of the female reproductive tract in the post partum period. The purpose of this study was to develop a novel AI technique for cattle that allows the deposition of spermatozoa directly into the ampulla in the immediate vicinity of the fertilization site. This new reproductive biotechnique was investigated with focus on semen origin, sperm dosage, semen preparation and time of insemination...
April 27, 2018: Theriogenology
https://www.readbyqxmd.com/read/29742689/total-robotic-surgery-for-pancreaticoduodenectomy-combined-with-rectal-cancer-anterior-resection-a-case-report-and-literature-review
#6
QunGuang Jiang, TaiYuan Li, DongNing Liu, Cheng Tang
RATIONALE: Synchronous double malignancies, including carcinoma of the ampulla of Vater and rectal carcinoma, are generally uncommon occurrences in the gastrointestinal tract. PATIENT CONCERNS: The present study report a case of a 37-year-old man who was incidentally found to suffer from carcinoma of the ampulla of Vater and rectal carcinoma. DIAGNOSES: The duodenoscopy was performed and revealed an ulcerated and bulky ampulla of Vater, the biopsy from which revealed a moderate-differentiated adenocarcinoma, A local hospital colonoscopy confirmed a tumor located in rectal 7 cm from the anal margin and biopsy-confirmed poorly differentiated adenocarcinoma...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29738360/intraobserver-and-interobserver-variability-in-the-assessment-of-dysplasia-in-ampullary-mucosal-biopsies
#7
Felicia D Allard, Jeffrey D Goldsmith, Gamze Ayata, Tracy L Challies, Robert M Najarian, Imad A Nasser, Helen Wang, Eric U Yee
Endoscopic mucosal biopsies of the ampulla of Vater (AmpBx) are obtained to histologically assess for dysplasia or carcinoma. However, biopsy material is often scant and a host of factors can induce histologic changes that pose diagnostic challenges. We sought to investigate observer variability in interpretation of AmpBx and the impact clinical data may have on diagnostic interpretation. Thirty-one cases from institutional archives were selected, including 12 cases of reactive atypia (RA), 8 indefinite for dysplasia (ID), and 11 showing low-grade dysplasia (LGD)...
May 5, 2018: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29736668/immunohistochemical-predictors-for-intestinal-and-pancreatobiliary-types-of-adenocarcinoma-of-the-ampulla-of-vater
#8
João Paulo Lemos da Silveira Santos, Carla Jorge Machado, Eduardo Paulino Junior, João Bernardo Sancio Rocha Rodrigues, Paula Teixeira Vidigal, Vivian Resende
OBJECTIVES: To investigate immunohistochemical predictors for intestinal and pancreatobiliary types of adenocarcinoma of ampulla of Vater and identify clinicopathological characteristics associated with the histological types and patient survival. METHODS: Immunohistochemical markers included MUC1, MUC2, MUC5AC, CDX2, CK7, and CK20. The data were analyzed by univariate and multivariate methods. The two-step cluster method was used to determine the best immunohistochemical markers to discriminate the intestinal from the pancreatobiliary type...
May 7, 2018: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29719849/avulsion-of-ampulla-of-vater-secondary-to-a-blunt-abdominal-injury-treated-with-pancreatoduodenectomy-a-case-report-and-literature-review
#9
Mustafa Ozsoy, Ogun Ersen, Zehra Ozsoy, Sezgin Yilmaz, Yüksel Arıkan
The incidence of complex hepatobiliary injury secondary to blunt abdominal injuries varies between 3.4 and 5%. A 25-year old male patient underwent an urgent operation due to a motorcycle accident. During intraabdominal exploration, Grade 4 laceration was detected at the liver and bleeding was controlled through primary repair. In the postoperative seventh day, he was referred due to 1500 cc bile leakage from the drainage tube. During the operation, an extensive Kocher maneuver was done and the second part of duodenum was observed to be exposed to total avulsion from the head of the pancreas...
April 2018: Bulletin of Emergency and Trauma
https://www.readbyqxmd.com/read/29708722/structural-and-functional-components-of-the-skate-sensory-organ-ampullae-of-lorenzini
#10
Xing Zhang, Ke Xia, Lei Lin, Fuming Zhang, Yanlei Yu, Kalib St Ange, Xiaorui Han, Eric Edsinger, Joel Sohn, Robert J Linhardt
The skate, a cartilaginous fish related to sharks and rays, possesses a unique electrosensitive sensory organ known as the ampullae of Lorenzini (AoL). This organ is responsible for the detection of weak electric field changes caused by the muscle contractions of their prey. While keratan sulfate (KS) is believed to be a component of a jelly that fills this sensory organ and has been credited with its high proton conductivity, modern analytical methods have not been applied to its characterization. Surprisingly, total glycosaminoglycan (GAG) analysis demonstrates that the KS from skate jelly is extraordinarily pure, containing no other GAGs...
May 9, 2018: ACS Chemical Biology
https://www.readbyqxmd.com/read/29707208/retrospective-cohort-of-pancreatic-and-vater-ampullary-adenocarcinoma-from-a-reference-center-in-mexico
#11
Jorge Sánchez-García, Fernando Candanedo-González, Anna Karen Félix-Félix, Damián Sánchez-Ramírez, Rafael Medrano-Guzmán, Miguel Quintana-Quintana, Yair Benjamín Baas-Cabrera, Eugenia Flores-Figueroa
Introduction: Pancreatic ductal adenocarcinoma (PDAC) and ampulla of Vater adenocarcinomas (AVAC) are periampullary tumors. These tumors have overlapping symptoms and a common treatment, but present differences in their survival and biology. No recent studies in Mexico have been published that describe the clinicopathological characteristics of these tumors. Therefore, the aim of this study was to describe the clinicopathological characteristics of PDAC and AVAC in patients at a reference center in Mexico...
June 2018: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/29687165/mechanism-underlying-the-effects-of-estrogen-deficiency-on-otoconia
#12
Liping Yang, Yinfang Xu, Yan Zhang, Sarath Vijayakumar, Sherri M Jones, Yunxia Yesha Wang Lundberg
Otoconia-related vertigo and balance deficits, particularly benign paroxysmal positional vertigo (BPPV), are common. Our recent studies in humans show that, while BPPV prevalence greatly increases with age in both genders, peri-menopausal women are especially susceptible. In the present study, we show that bilateral ovariectomized (OVX) mice have significant balance behavioral deficits, and that estrogen deficiency compromises otoconia maintenance and anchoring by reducing the expression of otoconial component and anchoring proteins...
April 23, 2018: Journal of the Association for Research in Otolaryngology: JARO
https://www.readbyqxmd.com/read/29684664/secnidazole-for-control-of-giardiasis-in-dairy-calves
#13
Andreia Volpato, Bruno F Fortuoso, Gabriela Campigotto, Patrícia Glombowsky, Nathieli B Bottari, Leandro S Lopes, Aleksandro Schafer Da Silva
The aim of this study was to verify whether secnidazole, given in a single oral dose (10 mg/kg), decreases or eliminates the excretion of Giardia duodenalis cysts. Holstein calves were raised from birth to 15 ± 2 days of age in individual stalls. Subsequently, 12 calves were grouped and housed in collective stalls. After seven days (day of life 21), we collected stool samples directly from the rectal ampulla in order to determine the degree of parasitic infection. Fecal examination was performed by a centrifugal-flotation technique, which allows for visualization and quantification of G...
April 11, 2018: Experimental Parasitology
https://www.readbyqxmd.com/read/29676030/eus-guided-hepaticogastrostomy
#14
Masahiro Itonaga, Keiichi Hatamaru, Masayuki Kitano
Recently, EUS-guided biliary drainage (EUS-BD), including rendezvous technique (EUS-RV), choledochoduodenostomy (EUS-CDS), hepaticogastrostomy (EUS-HGS) and antegrade stenting (EUS-AG), is the modality of choice when ERCP fails (1,2). EUS-RV is limited in patients with an accessible ampulla. EUS-CDS is limited in patients with distal bile duct obstruction and normal gastrointestinal anatomy. This article is protected by copyright. All rights reserved.
April 20, 2018: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/29675869/levator-avulsion-is-associated-with-pelvic-organ-prolapse-23-years-after-the-first-childbirth
#15
Ixora Kamisan Atan, Sylvia Lin, Hans P Dietz, Peter Herbison, Peter D Wilson
OBJECTIVES: This study aimed to ascertain the association between levator avulsion and pelvic organ prolapse (POP). METHODS: This was a cross-sectional study involving 195 women enrolled in a longitudinal cohort study and seen 20 years after an index birth. All had a standardized patient-administered questionnaire, the International Continence Society Pelvic Organ Prolapse Quantification assessment and 4D translabial ultrasound. Main outcome measures were objective POP clinically and on translabial ultrasound...
April 20, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29672360/cutaneous-metastasis-of-adenocarcinoma-of-the-ampulla-of-vater
#16
Angel Fernandez-Flores, David S Cassarino
Cutaneous metastases from an adenocarcinoma of the Ampulla of Vater are very rare, with only a few cases previously reported. We present here an additional case in a 57-year-old woman who complained of a painful growth on her frontal scalp that she had noticed 4 months earlier. Her medical history included an ampullary adenocarcinoma, which was diagnosed 4 years ago, excised through a Whipple procedure, and treated using chemotherapy and radiotherapy. The scalp biopsy showed a dermal and epidermotropic well-differentiated glandular neoplasm with abundant neutrophils within the luminae of the tumoral glands...
April 17, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/29666721/needle-knife-fistulotomy-for-the-rescue-an-unusual-cause-of-iatrogenic-extrahepatic-biliary-obstruction
#17
Laura L Ulmer, Lokesh K Jha, Neil Bhogal, Saurabh Kapur, Saurabh Chandan, Derrick Eichele, Ishfaq Bhat, Shailender Singh
A 71-year-old male presented to our institution with cholestatic hepatitis after having recently undergone upper endoscopy for treatment of gastrointestinal bleeding. Further investigation with endoscopic retrograde cholangiopancreatography revealed a hemostatic clip on the ampulla of Vater. After initial attempts at cannulation of the common bile duct were unsuccessful, biliary decompression was achieved by use of needle-knife fistulotomy. A common bile duct stent was placed and the liver function tests improved prior to discharge...
2018: Case Reports in Gastrointestinal Medicine
https://www.readbyqxmd.com/read/29659700/sex-steroids-drive-the-remodeling-of-oviductal-extracellular-matrix-in-cattle
#18
Angela Maria Gonella-Diaza, Fernando Silveira Mesquita, Everton Lopes, Kauê Ribeiro da Silva, Bruno Cogliati, Ricardo De Francisco Strefezzi, Mario Binelli
The extracellular matrix (ECM) is a group of molecules that offer structural and biochemical support to cells and interact with them to regulate their function. Also, growth factors (GFs) stored in the ECM can be locally released during the ECM remodeling process. Here, we hypothesize that the balance between ECM components and remodelers is regulated according to the ovarian steroid milieu to which the oviduct is exposed during the periovulatory period. Follicular growth was manipulated to generate cows that ovulated small follicles (SF-SCL; n = 20) or large follicles (LF-LCL; n = 21) and possess corresponding Estradiol (E2) and Progesterone (P4) plasmatic concentrations...
April 5, 2018: Biology of Reproduction
https://www.readbyqxmd.com/read/29653146/the-answer-is-in-the-ampulla
#19
Trilokesh D Kidambi, Karen C Bagatelos, James W Ostroff
No abstract text is available yet for this article.
April 10, 2018: Gastroenterology
https://www.readbyqxmd.com/read/29608905/regional-differences-in-endothelial-cell-cytoskeleton-junctional-proteins-and-phosphorylated-tyrosine-labeling-in-the-porcine-vortex-vein-system
#20
Priscilla Ern Zhi Tan, Paula K Yu, Hongfang Yang, Stephen J Cringle, Dao-Yi Yu
We previously demonstrated endothelial phenotype heterogeneity in the vortex vein system. This study is to further determine whether regional differences are present in the cytoskeleton, junctional proteins and phosphorylated tyrosine labeling within the system. The vortex vein system of twenty porcine eyes was perfused with labels for f-actin, claudin-5, VE-Cadherin, phosphorylated tyrosine and nucleic acid. The endothelial cells of eight different regions (choroidal veins, pre-ampulla, anterior ampulla, mid-ampulla, posterior ampulla, post-ampulla, intra-scleral canal and the extra-ocular vortex vein) were studied using confocal microscopy...
March 30, 2018: Experimental Eye Research
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