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https://www.readbyqxmd.com/read/29472978/kansas-provider-report-of-adolescent-vaccinations-in-their-practice
#1
Serina Padilla, Gretchen Homan, Matt Engel, Carolyn R Ahlers-Schmidt, Kari Harris
Background: Kansas falls consistently below average for adolescent vaccination of meningococcal (MCV), human papillomavirus (HPV), and influenza. Methods: For this study, the members of Kansas Chapter of the American Academy of Pediatrics were emailed a confidential electronic survey soliciting their impressions of vaccination in their practice. Results: Of 137 providers emailed, 61 (45%) completed the survey. Thirteen providers were excluded as they did not see/vaccinate adolescents or did not complete the survey...
November 2017: Kansas Journal of Medicine
https://www.readbyqxmd.com/read/29471184/targeting-metabotropic-glutamate-receptors-for-the-treatment-of-neuroinflammation
#2
REVIEW
Francesco Fazio, Martina Ulivieri, Claudia Volpi, Marco Gargaro, Francesca Fallarino
A large body of evidence suggests that neuroinflammation lies at the core of nearly all CNS disorders, including psychiatric disorders. Invading and local immune cells orchestrate the series of events that lead to either tissue repair or damage in response to neuroinflammation. Both lymphocytes and microglia express metabotropic glutamate (mGlu) receptors, which respond to glutamate or other endogenous activators (e.g. some kynurenine metabolites of tryptophan metabolism) influencing immune phenotype and the balance between pro-inflammatory and anti-inflammatory cytokines...
February 19, 2018: Current Opinion in Pharmacology
https://www.readbyqxmd.com/read/29467818/knowledge-transfer-a-worldwide-challenge-in-child-mental-health-a-recommendation-to-the-readership-of-capmh-concerning-the-revised-version-of-the-iacapap-textbook-of-child-and-adolescent-mental-health
#3
Anna T Maier, Rebecca C Brown, Joerg M Fegert
Background: Transfer of knowledge is an important issue throughout all scientific disciplines, especially in the medical and psycho-social field. The issue of worldwide knowledge transfer in child mental health is one of the aims and goals of the journal Child and Adolescent Psychiatry and Mental Health (CAPMH). The demand for mental health training is high worldwide, and especially in low- to lower-middle income countries, where inadequate access to knowledge resources in the field of child and adolescent mental health (CAMH) is prevalent...
2018: Child and Adolescent Psychiatry and Mental Health
https://www.readbyqxmd.com/read/29467138/-pathways-patient-centred-decision-counselling-for-women-at-risk-of-cancer-related-infertility-a-protocol-for-a-comparative-effectiveness-cluster-randomised-trial
#4
Terri Lynn Woodard, Aubri S Hoffman, Laura C Crocker, Deborah A Holman, Derek B Hoffman, Jusheng Ma, Roland L Bassett, Viola B Leal, Robert J Volk
INTRODUCTION: National guidelines recommend that all reproductive-age women with cancer be informed of their fertility risks and offered referral to fertility specialists to discuss fertility preservation options. However, reports indicate that only 5% of patients have consultations, and rates of long-term infertility-related distress remain high. Previous studies report several barriers to fertility preservation; however, initial success has been reported using provider education, patient decision aids and navigation support...
February 21, 2018: BMJ Open
https://www.readbyqxmd.com/read/29465473/characteristics-of-patients-with-hepatitis-c-virus-related-chronic-liver-diseases-just-before-the-era-of-oral-direct-acting-antiviral-therapy-in-italy
#5
Evangelista Sagnelli, Tommaso Stroffolini, Caterina Sagnelli, Bruno Cacopardo, Angelo Andriulli, Sergio Babudieri, Nicola Coppola, Giovanni B Gaeta, Piero L Almasio
BACKGROUND: In 2017, oral direct-acting antiviral (DAA) therapy for chronic hepatitis C virus (HCV) infection became available free of charge for all HCV-RNA-positive patients, irrespective of their fibrosis stage. AIM: The aim of this study was to evaluate the characteristics of HCV-related chronic liver disease (CLD) in Italy just before the introduction of DAA therapy. PATIENTS AND METHODS: Patients with CLD were enrolled in two national surveys conducted in 2001 and in 2014...
February 20, 2018: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29465425/optimization-of-nutrition-during-allogeneic-hematologic-stem-cell-transplantation
#6
Annic Baumgartner, Katja Hoskin, Philipp Schuetz
PURPOSE OF REVIEW: Malnutrition before and during hematopoietic stem cell transplantation (HSCT) is an independent risk factor for mortality in patients undergoing hematopoietic stem cell transplantation. Yet, optimal use of nutritional support to improve outcomes remains controversial. Our aim was to do an up-to-date literature review regarding nutritional therapy in allogeneic HSCT, the neutropenic diet and the use of immunonutrients. RECENT FINDINGS: Several observational studies find malnutrition to be associated with poor outcome, increased complications and lower overall survival...
February 19, 2018: Current Opinion in Clinical Nutrition and Metabolic Care
https://www.readbyqxmd.com/read/29465176/nurses-experiences-of-providing-care-to-bereaved-families-who-experience-unexpected-death-in-intensive-care-units-a-narrative-overview
#7
Aalia Shariff, Joanne Olson, Anna Santos Salas, Lisa Cranley
BACKGROUND: Death is a common occurrence in intensive care units (IC Us) and the complexity of care makes it difficult for nurses to find a balance between the patient's physical needs and the family's emotional needs, especially in circumstances of unexpected death. Cumulative or unresolved grief for families can have lasting negative repercussions. Nurses, therefore, need access to bereavement education in order to provide optimal- bereavement support. PURPOSE: The purpose of this review is to identify challenges and facilitators that nurses experience in delivering bereavement support during and after sudden or unexpected death in ICUs...
May 2017: Canadian Journal of Critical Care Nursing
https://www.readbyqxmd.com/read/29463488/digital-health-interventions-for-adults-with-type-2-diabetes-qualitative-study-of-patient-perspectives-on-diabetes-self-management-education-and-support
#8
Kingshuk Pal, Charlotte Dack, Jamie Ross, Susan Michie, Carl May, Fiona Stevenson, Andrew Farmer, Lucy Yardley, Maria Barnard, Elizabeth Murray
BACKGROUND: The prevalence of type 2 diabetes is increasing globally, and health services in many countries are struggling with the morbidity, mortality, and costs associated with the complications of this long-term condition. Diabetes self-management education (DSME) and behavioral support can reduce the risks of developing diabetes-related complications and improve glycemic control. However, their uptake is low. Digital health interventions (DHI) can provide sustained support and may overcome challenges associated with attending diabetes self-management sessions...
January 29, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29463476/defibulation-a-visual-reference-and-learning-tool
#9
Jasmine Abdulcadir, Sandra Marras, Lucrezia Catania, Omar Abdulcadir, Patrick Petignat
Female genital mutilation type III (infibulation) is achieved by narrowing the vaginal orifice by creating a covering seal, accomplished by cutting and appositioning the labia minora and/or labia majora, with or without clitoral excision. Infibulation is responsible for significant urogynecological, obstetrical, and psychosexual consequences that can be treated with defibulation (or de-infibulation), an operation that opens the infibulation scar, exposing the vulvar vestibule, vaginal orifice, external urethral meatus, and eventually the clitoris...
February 17, 2018: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29463246/next-generation-personalised-model-based-critical-care-medicine-a-state-of-the-art-review-of-in-silico-virtual-patient-models-methods-and-cohorts-and-how-to-validation-them
#10
REVIEW
J Geoffrey Chase, Jean-Charles Preiser, Jennifer L Dickson, Antoine Pironet, Yeong Shiong Chiew, Christopher G Pretty, Geoffrey M Shaw, Balazs Benyo, Knut Moeller, Soroush Safaei, Merryn Tawhai, Peter Hunter, Thomas Desaive
Critical care, like many healthcare areas, is under a dual assault from significantly increasing demographic and economic pressures. Intensive care unit (ICU) patients are highly variable in response to treatment, and increasingly aging populations mean ICUs are under increasing demand and their cohorts are increasingly ill. Equally, patient expectations are growing, while the economic ability to deliver care to all is declining. Better, more productive care is thus the big challenge. One means to that end is personalised care designed to manage the significant inter- and intra-patient variability that makes the ICU patient difficult...
February 20, 2018: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29463216/long-non-coding-rna-hotair-polymorphism-and-susceptibility-to-cancer-an-updated-meta-analysis
#11
Juan Li, Zhigang Cui, Hang Li, Xiaoting Lv, Min Gao, Zitai Yang, Yanhong Bi, Baosen Zhou, Zhihua Yin
BACKGROUND: An increasing number of publications are drawing attention to the associations between six common polymorphisms in HOX transcript anti-sense RNA (HOTAIR) and the risk of cancers, while these results have been controversial and inconsistent. We conducted an up-to-date meta-analysis to pool eligible studies and to further explore the possible relationships between HOTAIR polymorphisms (rs920778, rs7958904, rs12826786, 4,759,314, rs874945, and rs1899663) and cancer risk. METHODS: A systematic retrieval was conducted up to 1 July 2017 in the PubMed, Web of Science, and CNKI databases...
February 20, 2018: Environmental Health and Preventive Medicine
https://www.readbyqxmd.com/read/29460519/human-papilloma-virus-associated-with-oral-cancer-and-preventive-strategies-the-role-of-vaccines
#12
L Ottria, V Candotto, F Cura, L Baggi, C Arcuri, M Nardone, R M Gaudio, R Gatto, F Spadari, F Carinci
The aim of this paper is to describe the efficacy of Human Papilloma Virus (HPV) vaccines for preventing oral cancer. A systematic review of the literature was conducted to describe the state of the art about HPV vaccines for preventing oral cancer. The aspects of prevention and control of infection by administering vaccines and the diffusion of sexual education campaigns are discussed also. In recent years there has been a growing interest in HPV in dentistry, suggesting a role of such a family of viruses in the development of oral cancers as well as of the uterine cervix...
January 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29459947/association-of-vegetation-size-with-embolic-risk-in-patients-with-infective-endocarditis-a-systematic-review-and-meta-analysis
#13
Divyanshu Mohananey, Ashley Mohadjer, Gosta Pettersson, Jose Navia, Steven Gordon, Nabin Shrestha, Richard A Grimm, L Leonardo Rodriguez, Brian P Griffin, Milind Y Desai
Importance: Infective endocarditis is a life-threating condition with annual mortality of as much as 40% and is associated with embolic events in as many as 80% of cases. These embolic events have notable prognostic implications and have been linked to increased length of stay in intensive care units and mortality. A vegetation size greater than 10 mm has often been suggested as an optimal cutoff to estimate the risk of embolism, but the evidence is based largely on small observational studies...
February 19, 2018: JAMA Internal Medicine
https://www.readbyqxmd.com/read/29458783/precision-medicine-in-alk-rearranged-nsclc-a-rapidly-evolving-scenario
#14
REVIEW
Alfredo Addeo, Fabrizio Tabbò, Tim Robinson, Lucio Buffoni, Silvia Novello
IMPORTANCE: The identification of anaplastic lymphoma kinase (ALK) rearrangements in 2-5% of non-small cell lung cancer (NSCLC) patients led to the rapid clinical development of its oral tyrosine kinase inhibitor (TKI). Crizotinib was the first ALK inhibitor approved and utilised in the treatment of ALK+ NSCLC patients in the second line setting first and subsequently in the first line one. Since then many other ALK inhibitors have been developed (ceritinib, alectinib, brigatinib, lorlatinib,etc) and the treatment paradigm of these patients has considerably drifted...
February 2018: Critical Reviews in Oncology/hematology
https://www.readbyqxmd.com/read/29457854/metal-cluster-models-for-heterogeneous-catalysts-a-matrix-isolation-perspective
#15
Hans-Jörg Himmel, Olaf Hübner
Metal cluster models are of high relevance for establishing new mechanistic concepts for heterogeneous catalysis. The high reactivity and particular selectivity of metal clusters is caused by the wealth of low-lying electronically excited states that are often thermally populated. Thereby the metal clusters are flexible with regard to its electronic structure and can adjust their states to be appropriate for the reaction with a particular substrate. The matrix isolation technique is ideally suited for studying excited state reactivity...
February 19, 2018: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29456894/the-state-of-oa-a-large-scale-analysis-of-the-prevalence-and-impact-of-open-access-articles
#16
Heather Piwowar, Jason Priem, Vincent Larivière, Juan Pablo Alperin, Lisa Matthias, Bree Norlander, Ashley Farley, Jevin West, Stefanie Haustein
Despite growing interest in Open Access (OA) to scholarly literature, there is an unmet need for large-scale, up-to-date, and reproducible studies assessing the prevalence and characteristics of OA. We address this need using oaDOI, an open online service that determines OA status for 67 million articles. We use three samples, each of 100,000 articles, to investigate OA in three populations: (1) all journal articles assigned a Crossref DOI, (2) recent journal articles indexed in Web of Science, and (3) articles viewed by users of Unpaywall, an open-source browser extension that lets users find OA articles using oaDOI...
2018: PeerJ
https://www.readbyqxmd.com/read/29454795/advances-in-crc-prevention-screening-and-surveillance
#17
Evelien Dekker, Douglas K Rex
Colorectal cancer (CRC) is amongst the most commonly diagnosed cancers and causes of death from cancer across the world. CRC can, however, be detected in asymptomatic patients at a curable stage, and several studies have shown lower mortality among patients who undergo screening compared to those who do not. Using colonoscopy in CRC screening also results in the detection of precancerous polyps that can be directly removed during the procedure, thereby reducing the incidence of cancer. In the past decade, convincing evidence has appeared that the effectiveness of colonoscopy as CRC prevention tool is associated with the quality of the procedure...
February 15, 2018: Gastroenterology
https://www.readbyqxmd.com/read/29454716/emergency-management-of-priapism-in-the-united-kingdom-a-survey-of-current-practice
#18
Nicholas Bullock, Martin Steggall, Gareth Brown
BACKGROUND: Despite its importance, current practice in the emergency management of priapism in the United Kingdom is unknown. AIM: To evaluate current practice in the emergency management of priapism in the United Kingdom. METHODS: All "full," "associate urological specialist," and "trainee" members of the British Association of Urological Surgeons (BAUS; leading membership-based organization for practitioners of urologic surgery in the United Kingdom) were invited to participate in an online survey...
February 14, 2018: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29454607/italian-wikipedia-and-epilepsy-an-infodemiological-study-of-online-information-seeking-behavior
#19
Francesco Brigo, Simona Lattanzi, Giorgia Giussani, Laura Tassi, Nicola Pietrafusa, Carlo Andrea Galimberti, Raffaele Nardone, Nicola Luigi Bragazzi, Oriano Mecarelli
Wikipedia is the most commonly accessed source of health information by both healthcare professionals and the lay public worldwide. We aimed to evaluate information-seeking behavior of Internet users searching the Italian Wikipedia for articles related to epilepsy and its treatment. Using Pageviews Analysis, we assessed the total and mean monthly views of articles from the Italian Wikipedia devoted to epilepsy, epileptic syndromes, seizure type, and antiepileptic drugs (AEDs) from January 1, 2015 to October 31, 2017...
February 14, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29454271/the-complexation-of-rhizosphere-and-nonrhizosphere-soil-organic-matter-with-chromium-using-elemental-analysis-combined-with-ftir-spectroscopy
#20
Jiajun Wen, Zhongwu Li, Bin Huang, Ninglin Luo, Mei Huang, Ren Yang, Qiu Zhang, Xiuqing Zhai, Guangming Zeng
Complexation is a main mechanism controlling the reactions between soil organic matter (SOM) and heavy metals, which still have not been fully understood up to date. The objective of this study was to compare the SOM composition of nonrhizosphere and rhizosphere in low Cr treatment with that in high Cr treatment and to find out how metal concentrations affect the complexation with SOM. The results revealed that both the hydroxyl and the carboxyl were significantly different under different Cr treatment groups...
February 14, 2018: Ecotoxicology and Environmental Safety
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