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aortic aneurysm and TXA

Atsushi Aoki, Takanori Suezawa, Shu Yamamoto, Kenji Sangawa, Hiroyuki Irie, Nobuhiro Mayazaki, Satoshi Kamihira, Terutoshi Yamaoka
OBJECTIVE: The long-term outcomes of endovascular abdominal aortic aneurysm repair (EVAR) remain to be determined, but patients with aneurysm shrinkage after EVAR appear to have a good prognosis. We previously observed that antiplatelet therapy is a risk factor for lack of aneurysm shrinkage, a finding suggesting that coagulation and fibrinolysis play roles in shrinkage. We therefore studied the effect of antifibrinolytic therapy with tranexamic acid (TXA) on aneurysm shrinkage after EVAR...
May 2014: Journal of Vascular Surgery
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