Michael Verret, Nhat H Lam, Manoj Lalu, Stuart G Nicholls, Alexis F Turgeon, Daniel I McIsaac, Myriam Hamtiaux, John Bao Phuc Le, Ian Gilron, Lucy Yang, Mahrukh Kaimkhani, Alexandre Assi, David El-Adem, Makenna Timm, Peter Tai, Joelle Amir, Sriyathavan Srichandramohan, Abdulaziz Al-Mazidi, Nicholas A Fergusson, Brian Hutton, Fiona Zivkovic, Megan Graham, Maxime Lê, Allison Geist, Mélanie Bérubé, Patricia Poulin, Risa Shorr, Helena Daudt, Guillaume Martel, Jason McVicar, Husein Moloo, Dean A Fergusson
BACKGROUND: Postoperative patient-centred outcome measures are essential to capture the patient's experience after surgery. Although a large number of pharmacologic opioid minimisation strategies (i.e. opioid alternatives) are used for patients undergoing surgery, it remains unclear which strategies are most promising in terms of patient-centred outcome improvements. This scoping review had two main objectives: (1) to map and describe evidence from clinical trials assessing the patient-centred effectiveness of pharmacologic intraoperative opioid minimisation strategies in adult surgical patients, and (2) to identify promising pharmacologic opioid minimisation strategies...
February 7, 2024: British Journal of Anaesthesia