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https://www.readbyqxmd.com/read/29200984/mouth-rinsing-with-a-carbohydrate-solution-attenuates-exercise-induced-decline-in-executive-function
#1
Kana Konishi, Tetsuya Kimura, Atsushi Yuhaku, Toshiyuki Kurihara, Masahiro Fujimoto, Takafumi Hamaoka, Kiyoshi Sanada
Background: A decline in executive function could have a negative influence on the control of actions in dynamic situations, such as sports activities. Mouth rinsing with a carbohydrate solution could serve as an effective treatment for preserving the executive function in exercise. The purpose of this study was to examine the effects of mouth rinsing with a carbohydrate solution on executive function after sustained moderately high-intensity exercise. Methods: Eight young healthy participants completed 65 min of running at 75% V̇O2max with two mouth-rinsing conditions: with a carbohydrate solution (CHO) or with water (CON)...
2017: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/29104573/endothelial-regulator-of-calcineurin-1-promotes-barrier-integrity-and-modulates-histamine-induced-barrier-dysfunction-in-anaphylaxis
#2
Constanza Ballesteros-Martinez, Nerea Mendez-Barbero, Alma Montalvo-Yuste, Bettina M Jensen, Aída Gomez-Cardenosa, Lotte Klitfod, María Garrido-Arandia, Gloria Alvarez-Llamas, Carlos Pastor-Vargas, Fernando Vivanco, Lene Heise Garvey, Javier Cuesta-Herranz, Lars K Poulsen, Vanesa Esteban
Anaphylaxis, the most serious and life-threatening allergic reaction, produces the release of inflammatory mediators by mast cells and basophils. Regulator of calcineurin 1 (Rcan1) is a negative regulator of mast-cell degranulation. The action of mediators leads to vasodilation and an increase in vascular permeability, causing great loss of intravascular volume in a short time. Nevertheless, the molecular basis remains unexplored on the vascular level. We investigated Rcan1 expression induced by histamine, platelet-activating factor (PAF), and epinephrine in primary human vein (HV)-/artery (HA)-derived endothelial cells (ECs) and human dermal microvascular ECs (HMVEC-D)...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29062646/calcium-hydroxylapatite-combined-with-microneedling-and-ascorbic-acid-is-effective-for-treating-stretch-marks
#3
Gabriela Casabona, Paula Marchese
BACKGROUND: Stretch marks can have a negative psychological impact on some individuals. Methods are available for treating stretch marks, but high-quality evidence supporting their use is limited. We treat stretch marks using injections of diluted calcium hydroxylapatite (CaHA, Radiesse) filler combined with microneedling and topical ascorbic acid. This retrospective study evaluated the effectiveness of this combined therapy. METHODS: Subjects presented with red (n = 25) or white (n = 10) striae on their buttocks, thighs, knees, abdomen, and breasts...
September 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28991571/wrist-arthroscopy-under-portal-site-local-anesthesia-without-tourniquet-and-sedation
#4
REVIEW
Siu-Cheong Jeffrey Justin Koo, Pak-Cheong Ho
We had developed the technique of portal site local anaesthesia (PSLA) for wrist arthroscopy. Two percent lidocaine with 1:200,000 epinephrine is injected through a 25G needle to various portal sites. The radiocarpal joint is then distended with saline injection and portal is created with transverse superficial skin incision followed by dilation with curved hemostat. The patient is neither sedated, nor under general or regional anaesthesia. Tourniquet is not routinely used. PSLA can achieve satisfactory comfort level in 88% of our 111 patients without any complication...
November 2017: Hand Clinics
https://www.readbyqxmd.com/read/28859501/is-there-a-hormonal-regulation-of-phagocytosis-at-unicellular-and-multicellular-levels-a-critical-review
#5
György Csaba
Phagocytosis is an ancient cell function, which is similar at unicellular and multicellular levels. Unicells synthesize, store, and secrete multicellular (mammalian) hormones, which influence their phagocytosis. Amino acid hormones, such as histamine, serotonin, epinephrine, and melatonin stimulate phagocytosis, whereas peptide hormones, such as adrenocorticotropic hormone (ACTH), insulin, opioids, arginine vasopressin, and atrial natriuretic peptide decreased it, independently on their chemical structure or function in multicellulars...
September 1, 2017: Acta Microbiologica et Immunologica Hungarica
https://www.readbyqxmd.com/read/28817508/end-tidal-co2-guided-chest-compression-delivery-improves-survival-in-a-neonatal-asphyxial-cardiac-arrest-model
#6
Justin T Hamrick, Jennifer L Hamrick, Utpal Bhalala, Jillian S Armstrong, Jeong-Hoo Lee, Ewa Kulikowicz, Jennifer K Lee, Sapna R Kudchadkar, Raymond C Koehler, Elizabeth A Hunt, Donald H Shaffner
OBJECTIVES: To determine whether end-tidal CO2-guided chest compression delivery improves survival over standard cardiopulmonary resuscitation after prolonged asphyxial arrest. DESIGN: Preclinical randomized controlled study. SETTING: University animal research laboratory. SUBJECTS: 1-2-week-old swine. INTERVENTIONS: After undergoing a 20-minute asphyxial arrest, animals received either standard or end-tidal CO2-guided cardiopulmonary resuscitation...
November 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28782534/variation-in-adrenal-and-thyroid-hormones-with-life-history-stage-in-juvenile-northern-elephant-seals-mirounga-angustirostris
#7
J A Jelincic, M S Tift, D S Houser, D E Crocker
The classical approach to quantifying the impact of stressors on wildlife is through characterization of hormones associated with the generalized stress response. However, interpretation of hormone data can be difficult due to the range of natural variation within a species and potential confounds of individual and life-history variables. Blood adrenal and thyroid hormones were measured in 144 chemically immobilized yearling northern elephant seals (Mirounga angustirostris) to characterize variation between sexes and across semiannual haul-outs...
October 1, 2017: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/28740419/perineural-versus-intravenous-dexamethasone-as-an-adjuvant-in-regional-anesthesia-a-systematic-review-and-meta-analysis
#8
REVIEW
Wen-Ling Zhao, Xiao-Feng Ou, Jin Liu, Wen-Sheng Zhang
BACKGROUND: Dexamethasone is a common adjuvant for local anesthetics in regional anesthesia, but the optimal route of administration is controversial. Therefore, we did a systematic review and meta-analysis of randomized controlled trials to assess the effect of perineural versus intravenous dexamethasone on local anesthetic regional nerve-blockade outcomes. MATERIALS AND METHODS: Medline (through PubMed), Embase, Cochrane, Web of Science, and Biosis Previews databases were systematically searched (published from inception of each database to January 1, 2017) to identify randomized controlled trials...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28671236/vitamin-b-supplementation-what-s-the-right-choice-for-your-patients
#9
Laura G Leahy
As many patients turn to vitamins and supplements to enhance energy, relieve fatigue, or generally feel better, it is important to understand the connection between the B vitamins and psychiatric symptomatology. Vitamins B6, B8, and B12 have been shown not only to reduce psychiatric symptoms but also shorten the duration of illness. Vitamin B9, also known as folate or folic acid, has also been associated with psychiatric symptoms. However, when patients lack a specific genetic enzyme, which converts folate/folic acid to its most usable form, L-methylfolate, the neuroprotective and neuropsychiatric benefits are lost...
July 1, 2017: Journal of Psychosocial Nursing and Mental Health Services
https://www.readbyqxmd.com/read/28611138/cardiac-arrest-following-arteriovenous-fistula-manipulation-a-cautionary-note
#10
Miles Gandolfi, Bimbi S Fernando
Arteriovenous fistulas can lead to a number of different chronic complications. We describe a case where a patient developed a thrombosis within her brachiobasilic arteriovenous fistula, which was manually manipulated in order to restore fistula flow. This resulted in a pulseless electrical activity cardiac arrest within a few minutes. After ten minutes of chest compressions and intubation, there was return of spontaneous circulation. No epinephrine was given nor shocks administered. Patient was extubated within minutes and was alert, orientated and haemodynamically stable...
June 13, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28521865/exaggerated-glucagon-responses-to-hypoglycemia-in-women-with-polycystic-ovary-syndrome
#11
Susan Sam, Priyathama Vellanki, Sudha K Yalamanchi, Richard N Bergman, Andrea Dunaif
CONTEXT: Premenopausal women have blunted counter-regulatory hormone responses (CRR) to hypoglycemia compared to men. Postmenopausal women have CRR similar to men; the premenopausal pattern can be restored by estrogen. However, glucagon and pancreatic polypeptide (PP) responses remain lower in postmenopausal women than in men. Since hyperandrogenemia contributes to the metabolic phenotype of polycystic ovary syndrome (PCOS), we hypothesize that CRR to hypoglycemia especially of glucagon and PP is exaggerated in premenopausal women with PCOS compared to premenopausal control women...
June 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/28399479/changes-in-biochemical-markers-following-spinal-manipulation-a-systematic-review-and-meta-analysis
#12
REVIEW
Kesava Kovanur-Sampath, Ramakrishnan Mani, Jim Cotter, Angela Spontelli Gisselman, Steve Tumilty
The aim of this meta-analysis was to determine the effectiveness of spinal manipulation in influencing various biochemical markers in healthy and or symptomatic population. Electronic databases (n = 10) were searched (from inception till September 2016) and eight trials (325 participants) that met the inclusion criteria were included in the meta-analysis. Two authors independently extracted and assessed the risk of bias in included studies. Standardised mean differences for outcome measures were used to calculate effect sizes...
June 2017: Musculoskeletal Science & Practice
https://www.readbyqxmd.com/read/28178592/sertraline-and-venlafaxine-improves-motor-performance-and-neurobehavioral-deficit-in-quinolinic-acid-induced-huntington-s-like-symptoms-in-rats-possible-neurotransmitters-modulation
#13
Jaskamal Singh Gill, Sumit Jamwal, Puneet Kumar, Rahul Deshmukh
BACKGROUND: Huntington Disease is autosomal, fatal and progressive neurodegenerative disorder for which clinically available drugs offer only symptomatic relief. Emerging strides have indicated that antidepressants improve motor performance, restore neurotransmitters level, ameliorates striatal atrophy, increases BDNF level and may enhance neurogenesis. Therefore, we investigated sertraline and venlafaxine, clinically available drugs for depression with numerous neuroprotective properties, for their beneficial effects, if any, in quinolinic acid induced Huntington's like symptoms in rats...
April 2017: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/28025639/evaluation-of-bone-metabolism-in-critically-ill-patients-using-ctx-and-pinp
#14
Alexandra Gavala, Konstantinos Makris, Anna Korompeli, Pavlos Myrianthefs
Background. Prolonged immobilization, nutritional and vitamin D deficiency, and specific drug administration may lead to significant bone resorption. Methods and Patients. We prospectively evaluated critically ill patients admitted to the ICU for at least 10 days. Demographics, APACHE II, SOFA scores, length of stay (LOS), and drug administration were recorded. Blood collections were performed at baseline and on a weekly basis for five consecutive weeks. Serum levels of PINP, β-CTx, iPTH, and 25(OH)vitamin D were measured at each time-point...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27939824/pulmonary-platelet-accumulation-induced-by-catecholamines-its-involvement-in-lipopolysaccharide-induced-anaphylaxis-like-shock
#15
Zhiqian Yu, Hiroko Saito, Hirotada Otsuka, Yosuke Shikama, Hiromi Funayama, Mai Sakai, Shigeo Murai, Masanori Nakamura, Takashi Yokochi, Haruhiko Takada, Shunji Sugawara, Yasuo Endo
Intravenously injected lipopolysaccharides (LPS) rapidly induce pulmonary platelet accumulation (PPA) and anaphylaxis-like shock (ALS) in mice. Macrophages reportedly release catecholamines rapidly upon stimulation with LPS. Here, we examined the involvement of macrophage-derived catecholamines in LPS-induced PPA and ALS. A catecholamine or Klebsiella O3 (KO3) LPS was intravenously injected into mice, with 5-hydroxytryptamine in the lung being measured as a platelet marker. The tested catecholamines induced PPA, leading to shock...
February 2017: International Immunopharmacology
https://www.readbyqxmd.com/read/27829479/metabolic-and-reproductive-characteristics-of-replacement-beef-heifers-subjected-to-an-early-weaning-regimen-involving-high-concentrate-feeding
#16
A L Zezeski, V L McCracken, R K Poole, A Al Naib, J K Smith, M A McCann, M L Rhoads
In an effort to better understand the consequences of early weaning (EW) for replacement beef heifers, a two-phase experiment was conducted investigating the impact on metabolic function and documenting reproductive characteristics. In phase 1, Angus×Simmental heifers (n=35) were stratified by BW and sire, and randomly assigned to either a normal weaning (NW, n=18) or EW (n=17) treatment. EW heifers were weaned at 107±3 days of age and provided access to a concentrate-based ration ad libitum with limit-fed mixed grass hay...
May 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/27825728/csa-is-not-beneficial-long-term-in-heart-failure-patients-with-reduced-ejection-fraction
#17
REVIEW
Olaf Oldenburg, Andrew Coats
Central sleep apnea (CSA) affects many patients, with heart failure and results in hypoxia and nor-epinephrine release and is associated with high morbidity and mortality. Recent trials in the treatment of CSA using positive airway pressure therapies have failed to demonstrate improvement in mortality and as a result, the compensatory nature of CSA has been questioned. The detrimental effects from CSA are clear. While there may be a short term compensatory effect, the long term effects cause chronic insult to the cardiovascular system indicating that CSA should be treated, but alternative treatment options need to be considered...
January 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/27825364/mid-regional-pro-adrenomedullin-mr-proadm-a-marker-of-positive-fluid-balance-in-critically-ill-patients-results-of-the-envol-study
#18
Bernard Vigué, Pierre-Etienne Leblanc, Frédérique Moati, Eric Pussard, Hussam Foufa, Aurore Rodrigues, Samy Figueiredo, Anatole Harrois, Jean-Xavier Mazoit, Homa Rafi, Jacques Duranteau
BACKGROUND: The optimal control of blood volume without fluid overload is a main challenge in the daily care of intensive care unit (ICU) patients. Accordingly this study focused on the identification of biomarkers to help characterize fluid overload status. METHODS: Sixty-seven patients were studied from ICU admission to day 7 (D7). Blood and urine samples were taken daily and sodium and water balance strictly calculated resulting in a total cumulative assessment of ∆Na(+) and ∆H2O...
November 9, 2016: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/27796565/effects-of-jiaotaiwan-on-depressive-like-behavior-in-mice-after-lipopolysaccharide-administration
#19
Qian Zhe, Wang Sulei, Tao Weiwei, Long Hongyan, Wang Jianwei
Jiao-Tai-Wan (JTW), has been usually used for insomnia in traditional Chinese medicine (TCM). The previous study shown that JTW was benefit for depression-like behavior, but the possible mechanism is not clear. This study is to determine whether JTW was benefit for the treatment of lipopolysaccharide (LPS)-induced depression-like behavior in mice and explore its possible mechanism. All drugs were intragastrically administered once daily for 7 consecutive days. On the 7th day, LPS was injected into mice 30 min after drug administration...
April 2017: Metabolic Brain Disease
https://www.readbyqxmd.com/read/27426960/the-effect-of-working-on-call-on-stress-physiology-and-sleep-a%C3%A2-systematic-review
#20
REVIEW
Sarah J Hall, Sally A Ferguson, Anne I Turner, Samuel J Robertson, Grace E Vincent, Brad Aisbett
On-call work is becoming an increasingly common work pattern, yet the human impacts of this type of work are not well established. Given the likelihood of calls to occur outside regular work hours, it is important to consider the potential impact of working on-call on stress physiology and sleep. The aims of this review were to collate and evaluate evidence on the effects of working on-call from home on stress physiology and sleep. A systematic search of Ebsco Host, Embase, Web of Science, Scopus and ScienceDirect was conducted...
June 2017: Sleep Medicine Reviews
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