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https://www.readbyqxmd.com/read/29333517/safety-and-feasibility-of-platelet-rich-fibrin-matrix-injections-for-treatment-of-common-urologic-conditions
#1
Ethan L Matz, Amy M Pearlman, Ryan P Terlecki
Purpose: Autologous platelet rich plasma (PRP) is used increasingly in a variety of settings. PRP injections have been used for decades to improve angiogenesis and wound healing. They have also been offered commercially in urology with little to no data on safety or efficacy. PRP could theoretically improve multiple urologic conditions, such as erectile dysfunction (ED), Peyronie's disease (PD), and stress urinary incontinence (SUI). A concern with PRP, however, is early washout, a situation potentially avoided by conversion to platelet rich fibrin matrix (PRFM)...
January 2018: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/29333516/comparison-of-penile-length-at-6-24-months-between-children-with-unilateral-cryptorchidism-and-a-healthy-normal-cohort
#2
Dong Soo Ryu, Won Yeol Cho, Jae Min Chung, Dong Il Kang, Sang Don Lee, Sungchan Park
Purpose: Urologic diseases affected by testosterone can be associated with smaller penis size compared to the normal population. We sought to compare penile length in children with unilateral cryptorchidism and normative data from a cohort of healthy Korean boys. Materials and Methods: This study was performed in 259 Korean boys (212, normal cohort; 47, cryptorchidism) aged 6-24 months, each of whom had been brought to an outpatient clinic at one of five tertiary hospitals (Gyeongsangnam-do Province) between April 2014 and June 2015...
January 2018: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/29331084/baus-consensus-document-for-the-management-of-male-genital-emergencies-penile-amputation
#3
REVIEW
C J Shukla, G Brown, T Dorkin, M Lucky, R Pearcy, R W Rees, M Shabbir, D J Summerton, A Muneer
Male genital emergencies relating to the penis and scrotum are rare and require prompt investigation and surgical intervention. Clinicians are often unfamiliar with the management of these conditions and may not work in a specialist centre with on-site expertise in genitourethral surgery available. A series of consensus statements have been developed by an expert consensus comprising BAUS Section of Andrology and Genitourethral Surgery together with experts from units throughout the UK. Penile amputation is a rare gentile emergency and requires prompt intervention and microsurgical reconstruction...
January 13, 2018: BJU International
https://www.readbyqxmd.com/read/29327639/levels-of-uric-acid-in-erectile-dysfunction-of-different-aetiology
#4
Alessandra Barassi, Massimiliano Marco Corsi Romanelli, Raffaele Pezzilli, Elena Dozio, Clara Anna Linda Damele, Liborio Vaccalluzzo, Marco Di Dario, Giancarlo Goi, Nadia Papini, Luca Massaccesi, Giovanni Maria Colpi, Gian Vico Melzi d'Eril
Erectile dysfunction is a common disease characterized by endothelial dysfunction. The aetiology of ED is often multifactorial but evidence is being accumulated in favor of the proper function of the vascular endothelium that is essential to achieving and maintaining penile erection. Uric acid itself causes endothelial dysfunction via decreased nitric oxide production. This study aims to evaluate the serum uric acid (SUA) levels in 180 ED patients, diagnosed with the International Index of Erectile Function-5 (IIEF-5) and 30 non-ED control...
January 12, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29327306/strengthening-the-case-for-gender-neutral-and-the-nonavalent-hpv-vaccine
#5
REVIEW
Justin M Hintze, James P O'Neill
PURPOSE: The purpose of this review is to highlight the benefits of gender-neutral and the nonavalent human papillomavirus vaccination. Human papillomavirus infection is the most commonly sexually transmitted disease and is known to cause several types of cancers, including cervical, vulvar, vaginal, penile, oropharyngeal, anal, and rectal. 5% of cancers every year are attributable to human papillomavirus infection, with cervical cancer the most common and oropharyngeal cancer estimated to surpass the incidence of cervical cancer by 2020...
January 11, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29325832/the-pics-technique-a-novel-approach-for-residual-curvature-correction-during-penile-prosthesis-implantation-in-patients-with-severe-peyronie-s-disease-using-the-collagen-fleece-tachosil
#6
Georgios Hatzichristodoulou
BACKGROUND: Correction of residual curvature during inflatable penile prosthesis (IPP) implantation in patients with Peyronie's disease (PD) by plaque incision and grafting is a common approach. AIM: To present a novel technique for residual curvature correction during IPP implantation using collagen fleece (TachoSil, Baxter Healthcare Corp, Deerfield, IL, USA). METHODS: After the IPP (Titan Touch, Coloplast, Minneapolis, MN, USA) is placed, the implant is inflated maximally...
January 8, 2018: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29325693/updates-in-the-eighth-edition-of-the-tumor-node-metastasis-staging-classification-for-urologic-cancers
#7
REVIEW
Gladell P Paner, Walter M Stadler, Donna E Hansel, Rodolfo Montironi, Daniel W Lin, Mahul B Amin
The Tumor-Node-Metastasis (TNM) classification on cancer staging, jointly developed by the American Joint Commission on Cancer (AJCC) and the Union for International Cancer Control (UICC), has been updated to its 8th edition with two contemporaneous versions published by the AJCC and UICC. While the goal of the AJCC and UICC is to have identical TNM staging systems, differences exist between these two publications including in the staging of urologic cancers. Among several new facets in the AJCC staging manual, a select few of greater import include an expanded section on imaging, presentation of levels of evidence for significant changes, and endorsement of risk assessment models that pass the AJCC quality criteria such as in prostate cancer...
January 8, 2018: European Urology
https://www.readbyqxmd.com/read/29319487/validation-of-predictors-for-lymph-node-status-in-penile-cancer-results-from-a-population-based-cohort
#8
X Melody Qu, D Robert Siemens, Alexander V Louie, Darwin Yip, Aamer Mahmud
INTRODUCTION: The ability to predict lymph node (LN) status is essential in the management of men with localized squamous cell carcinoma (SCC) of the penis. There has been limited external validation of available risk stratification tools, particularly in routine clinical care. The objective of this study was to evaluate the predictive variables of LN metastases within a large population-based cohort of patients. METHODS: In this population-based cohort study, surgical pathology reports were linked to the population-based Ontario Cancer Registry to identify all patients who were diagnosed with penile cancer in Ontario, Canada...
December 22, 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/29319007/calpain-inhibition-improves-erectile-function-in-diabetic-mice-via-upregulating-endothelial-nitric-oxide-synthase-expression-and-reducing-apoptosis
#9
Hao Li, Li-Ping Chen, Tao Wang, Shao-Gang Wang, Ji-Hong Liu
Calpain activation contributes to hyperglycemia-induced endothelial dysfunction and apoptosis. This study was designed to investigate the role of calpain inhibition in improving diabetic erectile dysfunction (ED) in mice. Thirty-eight-week-old male C57BL/6J mice were divided into three groups: (1) nondiabetic control group, (2) diabetic mice + vehicle group, and (3) diabetic mice + MDL28170 (an inhibitor of calpain) group. Type 1 diabetes was induced by intraperitoneal injection of streptozotocin at 60 mg kg-1 body weight for 5 consecutive days...
January 9, 2018: Asian Journal of Andrology
https://www.readbyqxmd.com/read/29316825/on-surmounting-the-barriers-to-hpv-vaccination-we-can-do-better
#10
Aria C Attia, Judith Wolf, Ana Nuñez
The major impediment to increased HPV vaccination coverage in young males and females is lack of health care provider recommendation. Despite its efficacy in preventing cervical cancer, HPV vaccination in females (49.5%) and males (37.5%) ages 13 through 17 falls well below the Centers for Disease Control and Prevention's (CDC) Healthy People 2020 target of 80% coverage. Parents' willingness to vaccinate their child has been shown to be much higher when physicians share personal vaccination decisions for their own children as well as what other parents have done at that particular clinic...
January 10, 2018: Annals of Medicine
https://www.readbyqxmd.com/read/29315704/accessory-fold-of-skin-on-the-ventral-surface-of-the-penis-is-it-a-redundant-prepuce
#11
S B Nayak, S U Pai, M G Shenoy, D Reghunathan
Variations in the skin of the prepuce are very rare. We report here a variation of the penile skin as observed in an adult male cadaver aged approximately 65 years. The penis was covered by thin nonhairy skin. The glans was not covered with prepuce. There was no evidence of circumcision. The ventral surface of the penis, adjacent to the glans, had a huge fold of skin. This fold resembled the prepuce and had a hole in it. The glans penis had a normal urethral meatus. There was no evidence of hypospadias as the entire ventral surface of the penis was covered completely by the skin...
January 7, 2018: Andrologia
https://www.readbyqxmd.com/read/29310171/re-clinical-experience-with-penile-traction-therapy-among-men-undergoing-collagenase-clostridium-histolyticum-for-peyronie-disease
#12
Allen F Morey
No abstract text is available yet for this article.
January 2018: Journal of Urology
https://www.readbyqxmd.com/read/29310161/re-long-term-outcomes-of-ams-spectra%C3%A2-penile-prosthesis-implantation-and-satisfaction-rates
#13
Allen D Seftel
No abstract text is available yet for this article.
January 2018: Journal of Urology
https://www.readbyqxmd.com/read/29310160/re-inflatable-penile-prosthesis-as-tissue-expander-what-is-the-evidence
#14
Allen D Seftel
No abstract text is available yet for this article.
January 2018: Journal of Urology
https://www.readbyqxmd.com/read/29310158/re-glans-necrosis-following-penile-prosthesis-implantation-prevention-and-treatment-suggestions
#15
Allen D Seftel
No abstract text is available yet for this article.
January 2018: Journal of Urology
https://www.readbyqxmd.com/read/29307683/effect-of-starting-penile-rehabilitation-with-sildenafil-immediately-after-robot-assisted-laparoscopic-radical-prostatectomy-on-erectile-function-recovery-a-prospective-randomized-trial
#16
Jung Ki Jo, Seong Jin Jeong, Jong Jin Oh, Sang Wook Lee, Sangchul Lee, Sung Kyu Hong, Seok-Soo Byun, Sang Eun Lee
PURPOSE: It has not been clearly proven in real practice whether early rehabilitation with phosphodiesterase type 5 inhibitors starting immediately after radical prostatectomy improves erectile function recovery more effectively compared with delayed treatment with the same regimen. We performed a prospective randomised trial to identify this. PATIENTS AND METHODS: Patients with prostate cancer and pre-operative International Index of Erectile Function (IIEF)-5 score ≥17 were randomly assigned to regularly receive sildenafil 100mg twice a week for 3 months immediately after urethral catheter removal (early group) or only at 3 months after nerve-sparing robot-assisted laparoscopic radical prostatectomy (delayed group)...
January 4, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29306557/penile-cancer-sparing-surgery-the-balance-between-oncological-cure-and-functional-preservation
#17
Kevin R Loughlin
Penile cancer presents the dual challenge of achieving oncological cure while ,simultaneously, attempting to preserve sexual function. Herein is a review of the issues involved in appropriate patient selection as well as surgical technique. Recommendations regarding follow up and monitoring are also provided.
January 3, 2018: Urologic Oncology
https://www.readbyqxmd.com/read/29303925/local-anesthetic-systemic-toxicity-a-review-of-recent-case-reports-and-registries
#18
Marina Gitman, Michael J Barrington
This review summarizes presenting features, management, and outcomes of local anesthetic systemic toxicity (LAST) from published cases and those submitted to online registries capturing use of intravenous lipid emulsion (ILE) therapy. The results of single-center and multicenter registries and epidemiologic studies complement this information. Between March 2014 and November 2016, 47 separate cases of LAST were described in 35 peer-reviewed articles. Local anesthetic systemic toxicity events occurred as a result of penile blocks (23%), local infiltration (17%), and upper/lower extremity, torso, and neuraxial blockade...
January 5, 2018: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/29299903/delayed-ejaculation-pathophysiology-diagnosis-and-treatment
#19
REVIEW
Ibrahim A Abdel-Hamid, Omar I Ali
Delayed ejaculation (DE) is a poorly defined and uncommon form of male sexual dysfunction, characterized by a marked delay in ejaculation or an inability to achieve ejaculation. It is often quite concerning to patients and their partners, and sometimes frustrates couples' attempts to conceive. This article aims to review the pathophysiology of DE and anejaculation (AE), to explore our current understanding of the diagnosis, and to present the treatment options for this condition. Electronic databases were searched from 1966 to October 2017, including PubMed (MEDLINE) and Embase...
January 2018: World Journal of Men's Health
https://www.readbyqxmd.com/read/29299902/role-of-penile-prosthesis-in-priapism-a-review
#20
REVIEW
Amit G Reddy, Laith M Alzweri, Andrew T Gabrielson, Gabriel Leinwand, Wayne J G Hellstrom
Ischemic priapism is a urological emergency that has been associated with long-standing and irreversible adverse effects on erectile function. Studies have demonstrated a linear relationship between the duration of critically ischemic episodes and the subsequent development of corporal fibrosis and irreversible erectile function loss. Placement of a penile prosthesis is a well-established therapeutic option for the management of erectile dysfunction secondary to ischemic priapism, and will be the focus of this review...
January 2018: World Journal of Men's Health
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