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https://www.readbyqxmd.com/read/29441008/diagnosis-and-treatment-of-cerebral-venous-thrombosis-a-review
#1
REVIEW
Yaxi Luo, Xin Tian, Xuefeng Wang
Cerebral venous thrombosis (CVT), also called cerebral venous sinus thrombosis (CVST), is a cerebrovascular disease with diverse clinical manifestations that often affects young adults, women of childbearing age, and children. It's most common clinical manifestations are headache, seizures, altered consciousness, and neurological focal signs on physical examination. CVT can manifest as a single symptom, or it can present as a syndrome consisting of multiple symptoms. This non-specific clinical picture makes diagnosing CVT difficult...
2018: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29438263/validity-and-acceptance-of-color-vision-testing-on-smartphones
#2
Omar K Ozgur, Trisha S Emborgo, Mark B Vieyra, Rebecca F Huselid, Rudrani Banik
BACKGROUND: Ishihara color plates (ICP) are the most commonly used color vision test (CVT) worldwide. With the advent of new technologies, attempts have been made to streamline the process of CVT. As hardware and software evolve, smartphone-based testing modalities may aid ophthalmologists in performing more efficient ophthalmic examinations. We assess the validity of smartphone color vision testing (CVT) by comparing results using the Eye Handbook (EHB) CVT application with standard Ishihara color plates (ICP)...
March 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29436443/diagnosis-and-management-of-cerebral-venous-thrombosis
#3
Roya Behrouzi, Martin Punter
Cerebral venous thrombosis (CVT) is rare and accounts for 0.5% of all strokes. Its clinical presentation is variable and diagnosis requires a high index of clinical suspicion in conjunction with neuroradiological diagnostic support. Treatment options are limited and are mostly based on consensus. Therefore, familiarity with international guidelines is important. Outcome is often good and most patients make a full recovery, although a small proportion suffers death or disability. Here, we describe the clinical features, risk factors, acute imaging features, management and complications of CVT...
February 2018: Clinical Medicine: Journal of the Royal College of Physicians of London
https://www.readbyqxmd.com/read/29402471/direct-oral-anticoagulant-use-in-patients-with-thrombophilia-antiphospholipid-syndrome-or-venous-thrombosis-of-unusual-sites-a-narrative-review
#4
REVIEW
Laurent Bertoletti, Ygal Benhamou, Yannick Béjot, Sylvestre Marechaux, Saida Cheggour, Boris Aleil, Nicolas Lellouche, Jean-Guillaume Dillinger, Aurélien Delluc
Direct oral anticoagulants (DOACs) are indicated in the treatment and prevention of venous thromboembolism (VTE). However, the use of DOACs in unusual VTE, including cerebral venous thrombosis (CVT) and splanchnic venous thrombosis (SVT), and in patients with biological thrombophilia including minor thrombophilia (Factor V Leiden and prothrombin G20210A), major innate thrombophilia (protein C and S deficiency, and antithrombin) and major acquired thrombophilia (antiphospholipid syndrome [APS]), remains controversial due to the paucity of available data...
February 2, 2018: Blood Reviews
https://www.readbyqxmd.com/read/29390539/oral-contraceptives-caused-venous-sinus-thrombosis-complicated-with-cerebral-artery-infarction-and-secondary-epileptic-seizures-a-case-report-and-literature-review
#5
Feng Xu, Cuifang Liu, Xiaobo Huang
RATIONALE: Venous sinus thrombosis is a special type of cerebrovascular disease. Its incidence is low and its symptoms are lack of specificity. And its early diagnosis and treatment are very difficult. PATIENT CONCERNS: This paper reported a rare case of a 43-year-old female who presented with cerebral venous thrombosis (CVT) complicated with cerebral artery infarction and secondary epileptic seizures due to oral contraceptives. DIAGNOSES: The final diagnosis was intracranial venous sinus thrombosis, acute cerebral infarction in the left parietal lobe, intracranial hypertension syndrome, and continuous epilepsy...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29388927/-the-comparative-analysis-of-the-influence-of-the-supervised-exercise-training-and-home-based-exercise-training-on-the-psychological-status-of-the-following-coronary-artery-bypass-grafting
#6
S A Pomeshkina, E B Loktionova, V A Bezzubova, N V Arkhipova, I М Borovik, O L Barbarash
This article was designed to report the results of the comparative analysis of the influence of the home-based exercise training (HBT) and the supervised exercise training in the form of the controlled training (CVT) under conditions of outpatient rehabilitative treatment on the patients' quality of life (QoL) and psychological status (including manifestations of anxiety and depression) following coronary artery bypass grafting (CABG). AIM: The objective of the present study was to evaluate the consequences of the application of different programs of physical rehabilitation under the outpatient conditions on the psychoemotional status and quality of life of the patients who had undergone coronary artery bypass grafting...
December 28, 2017: Voprosy Kurortologii, Fizioterapii, i Lechebnoĭ Fizicheskoĭ Kultury
https://www.readbyqxmd.com/read/29370521/interpolative-separable-density-fitting-through-centroidal-voronoi-tessellation-with-applications-to-hybrid-functional-electronic-structure-calculations
#7
Kun Dong, Wei Hu, Lin Lin
The recently developed interpolative separable density fitting (ISDF) decomposition is a powerful way for compressing the redundant information in the set of orbital pairs, and has been used to accelerate quantum chemistry calculations in a number of contexts. The key ingredient of the ISDF decomposition is to select a set of non-uniform grid points, so that the values of the orbital pairs evaluated at such grid points can be used to accurately interpolate those evaluated at all grid points. The set of non-uniform grid points, called the interpolation points, can be automatically selected by a QR factorization with column pivoting (QRCP) procedure...
January 25, 2018: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/29367996/catalytic-effect-of-a-single-water-molecule-on-the-oh-ch2nh-reaction
#8
Mohamad Akbar Ali, Balaganesh M, K C Lin
In recent work, there has been considerable speculation about the atmospheric reaction of methylenimine (CH2NH), because this compound is highly reactive, soluble in water, and sticky, thus posing severe experimental challenges. In this work, we have revisited the kinetics of the OH + CH2NH reaction assisted by a single water molecule. The potential energy surfaces (PESs) for the water-assisted OH + CH2NH reaction were calculated using the CCSD(T)//BH&HLYP/aug-cc-pVTZ levels of theory. The rate coefficients for the bimolecular reaction pathways CH2NHH2O + OH and CH2NH + H2OHO were computed using canonical variational transition state theory (CVT) with small curvature tunneling correction...
January 25, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29366703/evidence-for-single-dose-protection-by-the-bivalent-hpv-vaccine-review-of-the-costa-rica-hpv-vaccine-trial-and-future-research-studies
#9
Aimée R Kreimer, Rolando Herrero, Joshua N Sampson, Carolina Porras, Douglas R Lowy, John T Schiller, Mark Schiffman, Ana Cecilia Rodriguez, Stephen Chanock, Silvia Jimenez, John Schussler, Mitchell H Gail, Mahboobeh Safaeian, Troy J Kemp, Bernal Cortes, Ligia A Pinto, Allan Hildesheim, Paula Gonzalez
The Costa Rica Vaccine Trial (CVT), a phase III randomized clinical trial, provided the initial data that one dose of the HPV vaccine could provide durable protection against HPV infection. Although the study design was to administer all participants three doses of HPV or control vaccine, 20% of women did not receive the three-dose regimens, mostly due to involuntary reasons unrelated to vaccination. In 2011, we reported that a single dose of the bivalent HPV vaccine could be as efficacious as three doses of the vaccine using the endpoint of persistent HPV infection accumulated over the first four years of the trial; findings independently confirmed in the GSK-sponsored PATRICIA trial...
January 20, 2018: Vaccine
https://www.readbyqxmd.com/read/29362628/cerebral-venous-thrombosis-in-a-patient-with-iron-deficiency-anemia-and-thrombocytopenia-a-case-report
#10
Walaa A Kamel, Jasem Y Al-Hashel, K John Alexander, Fathi Massoud, Fatima Al Shawaf, Ibtisam E Al Huwaidi
AIM: To report a potential association of thrombosis, thrombocytopenia with iron deficiency anaemia. CASE REPORT: A 43-year-old female experienced an episode of a headache, with bilateral papilledema by neurological examination, magnetic resonance venography (MRV) brain showed cerebrovenous thrombosis (CVT), iron deficiency anaemia and thrombocytopenia by blood investigations, that was treated with iron supplementations and anticoagulation. CONCLUSION: In this patient, cerebrovenous thrombosis (CVT) was discovered in a patient with thrombocytopenia and iron deficiency anaemia and treated with iron supplements and anticoagulation, we concluded that thrombocytopenia is not a protective factor against thrombosis especially with iron deficiency anaemia...
December 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29341411/the-effect-of-recanalization-on-long-term-neurological-outcome-after-cerebral-venous-thrombosis
#11
E Rezoagli, I Martinelli, D Poli, U Scoditti, S M Passamonti, P Bucciarelli, W Ageno, F Dentali
Essentials The role of cerebral venous thrombosis (CVT) recanalization on neurologic outcome is still debated. We studied a large cohort of 508 CVT patients with 419 patient years of radiological follow-up. Recanalization rate is high during the first months after CVT and neurologic outcome is favorable. High recanalization grade of CVT independently predicts good neurological outcome. SUMMARY: Background Studies with limited sample size and with discordant results described the recanalization time-course of cerebral venous thrombosis (CVT)...
January 16, 2018: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/29322704/evaluation-of-cerebral-venous-thrombosis-by-ct-mri-and-mr-venography
#12
Pratibha Issar, Sirasapalli Chinna, Sanjeev Kumar Issar
Objective: To study and compare cerebral parenchymal changes and sinuses involvement in CT with MRI and MRV in Cerebral Venous Thrombosis patients. Method: This study was carried out in the Department of Radiodiagnosis, JLN Hospital and Research Center, Bhilai, Chhattisgarh from October 2012 to Nov 2014 and includes fifty patients of all age groups presenting with clinical symptoms of CVT, admitted in Neurology, Neurosurgery, Medicine, Pediatric, obstetric and Gynecology wards...
November 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/29320205/heavy-atom-secondary-kinetic-isotope-effect-on-h-tunneling
#13
André Kristopher Eckhardt, Dennis Gerbig, Peter R Schreiner
Although frequently employed, heavy atom kinetic isotope effects (KIE) have not been reported for quantum mechanical tunneling reactions. Here we examine the secondary KIE through 13C substitution of the carbene atom in methylhydroxycarbene (H3C-C̈-OH) in its [1,2]H tunneling shift reaction to acetaldehyde (H3C-CHO). Our study employs matrix isolation IR spectroscopy in various inert gases and quantum chemical computations. Depending on the choice of the matrix host gas the KIE varies within a range of 1.0 in xenon and 1...
January 10, 2018: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/29313820/ferromagnetism-in-cvt-grown-tungsten-diselenide-single-crystals-with-nickel-doping
#14
Muhammad Habib, Zahir Muhammad, Rashid Khan, Chuan Qiang Wu, Zia Ur Rehman, Yu Zhou, Hengjie Liu, Li Song
Two dimensional (2D) single crystal layered transition materials have got extensive considerations owing to their interesting magnetic properties originated from their lattices and strong spin-orbit coupling, which make them of vital importance for spintronic application. Herein, we present synthesis of a highly crystalline tungsten diselenide layered single crystals grown by chemical vapor transport technique and doped with nickel (Ni) to tailor its magnetic properties. The pristine WSe2 single crystal and Ni doped one were characterized and analyzed for magnetic properties from both experimental and computational aspects...
January 9, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29310406/cerebral-venous-thrombosis-originating-from-internal-jugular-vein-outflow-impairment-a-case-report
#15
Chunxiao Li, Li Sun, Xiuzhen Zhao, Mingqin Zhu, Ying Zhang
RATIONALE: Cerebral venous thrombosis (CVT) comprises a group of cerebral vascular diseases resulting from cerebral venous outflow obstruction caused by various etiologies. The etiology of CVT is complex, including infectious and noninfectious factors. The diagnosis is difficult. As a result, many patients are misdiagnosed or never diagnosed. This patient was diagnosed with CVT due to unilateral internal jugular vein compression. PATIENT CONCERNS: In this report, we present a case of acute onset CVT in a 15-year-old female patient who presented with a headache, nausea, and vomiting as the main clinical manifestations...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29305265/the-nem1-spo7-protein-phosphatase-complex-is-required-for-efficient-mitophagy-in-yeast
#16
Xueyan Xu, Koji Okamoto
Mitochondria-targeted selective autophagy, termed mitophagy, is an evolutionarily conserved process that contributes to mitochondrial quantity and quality control. Mitophagy requires elaborate membrane biogenesis of autophagosomes surrounding mitochondria, although how this process is regulated remains obscure. We show here that mitophagy is strongly suppressed in yeast cells lacking Nem1 or Spo7, two proteins forming a heterodimeric protein phosphatase complex known to be important for proper shaping of the nucleus and endoplasmic reticulum (ER)...
January 2, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29303679/teleneurology-for-veterans-in-a-major-metropolitan-area
#17
Steven S Schreiber
BACKGROUND: The recent growth in telehealth has been facilitated by the need to deliver healthcare to patients living in remote or rural areas. In contrast, the role of telehealth in more urban settings is less clear. A teleneurology program was established in 2011 at the Tibor Rubin VA Medical Center (TRVAMC) in Long Beach, California. A review of teleneurology encounters was conducted to assess the feasibility of applying this telehealth modality to patients with chronic neurological disorders living in an urban setting...
January 5, 2018: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/29290117/reactivity-of-hydrogen-peroxide-with-br-and-i-atoms
#18
Camille Fortin, Sarah Khanniche, Dorra Khiri, Valérie Fèvre-Nollet, Patrick Lebègue, Fréderic Cousin, Ivan Cernusak, Florent Louis
The reaction mechanisms of Br and I atoms with H2O2 have been investigated using DFT and high-level ab initio calculations. The H-abstraction and OH-abstraction channels were highlighted. The geometries of the stationary points were optimized at the B3LYP/aug-cc-pVTZ level of theory and the energetics were recalculated with the coupled cluster theory. Spin-orbit coupling for each halogenated species was also explicitly computed by employing the MRCI level of theory. Thermochemistry for HOBr and HOI has been revised and updated standard enthalpies of formation at 298 K for HOBr and HOI are the following: ΔfH°298K(HOBr) = (-66...
December 30, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/29284999/high-burden-of-stroke-risk-factors-in-developing-country-the-case-study-of-bosnia-herzegovina
#19
Marija Bender, Edin Jusufovic, Vesna Railic, Sima Kelava, Selma Tinjak, Damir Dzevdetbegovic, Dario Mot, Mensuda Tresnjo, Sandra Lakicevic, Natasa Pejanovic-Skobic, Osman Sinanovic
Introduction: The burden of stroke has been increasing worldwide, especially in developing countries. Very few data regarding epidemiology of stroke are available in Bosnia and Herzegovina (BH). Patients and methods: We undertook a retrospective hospital-based study in all hospitals existing in five cantons and one district of BH. The patients were recruited between January 1st, 2014, and December 31st, 2014, and only first-ever-in-lifetime strokes (FES) were included for evaluation...
December 2017: Materia Socio-medica
https://www.readbyqxmd.com/read/29277281/yield-of-computed-tomography-ct-angiography-in-patients-with-acute-headache-normal-neurological-examination-and-normal-non-contrast-ct-a-meta-analysis
#20
Imanda M E Alons, Ben F J Goudsmit, Korne Jellema, Marianne A A van Walderveen, Marieke J H Wermer, Ale Algra
BACKGROUND: Patients with acute severe headache, normal neurological examination, and a normal noncontrast head computed tomography (NCCT) may still have subarachnoid hemorrhage, cerebral venous thrombosis (CVT), cervical arterial dissection, or reversible cerebral vasoconstriction syndrome (RCVS). Computed tomography angiography (CTA) is used increasingly in the emergency department for evaluating this, but its added value remains controversial. METHODS: We retrospectively collected data on the diagnostic yield of CTA in patients with acute severe headache, normal neurological examination, and normal NCCT who received additional CTA in the acute phase in 2 secondary referral centers for vascular neurology...
December 22, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
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