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https://www.readbyqxmd.com/read/28441847/-feasibility-of-device-closure-for-multiple-atrial-septal-defects-using-3d-printing-and-ultrasound-guided-intervention-technique
#1
X Qiu, B Lü, N Xu, C W Yan, W B Ouyang, Y Liu, F W Zhang, Z Q Yue, K J Pang, X B Pan
Objective: To investigate the feasibility of trans-catheter closure of multiple atrial septal defects (ASD) monitored by trans-thoracic echocardiography (TTE) under the guidance of 3D printing heart model. Methods: Between April and August 2016, a total of 21 patients (8 male and 13 female) with multiple ASD in Fuwai Hospital of Chinese Academy of Medical Sciences underwent CT scan and 3-dimensional echocardiography for heart disease model produced by 3D printing technique. The best occlusion program was determined through the simulation test on the model...
April 25, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28441632/emergency-computed-tomography-in-patients-with-first-seizure
#2
Kaisa Kotisaari, Pekka Virtanen, Nina Forss, Daniel Strbian, Filip Scheperjans
PURPOSE: To determine the frequency of emergent imaging findings on head computed tomography (CT) in an adult population of first seizure (FS) patients presenting to an emergency department (ED); and to search for associations between clinical features and emergent imaging findings among these patients. METHODS: For this retrospective registry-based study, adult FS patients presenting to Helsinki University Hospital ED in 2006 were identified based on ICD-10 diagnosis...
April 17, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/28441153/discharge-criteria-for-the-late-preterm-infant-a-review-of-the-literature
#3
Jenny M Quinn, Marteen Sparks, Sheila M Gephart
BACKGROUND: Standardized late preterm infant (LPI) discharge criteria ensure best practice and help guide the neonatal provider to determine the appropriate level of care following birth. However, the location can vary from the well newborn setting to the neonatal intensive care unit (NICU). PURPOSE: The purpose of this review is to examine differences in LPI discharge criteria between the well newborn setting and the NICU by answering the clinical questions, "What are the recommended discharge criteria for the LPI and do they differ if admitted to the well newborn setting versus the NICU?" SEARCH STRATEGY: Databases searched include CINAHL, TRIP, PubMed, and the Cochrane Library...
April 24, 2017: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/28441087/using-the-payoff-time-in-decision-analytic-models-a-case-study-for-using-statins-in-primary-prevention
#4
Alexander Thompson, Bruce Guthrie, Katherine Payne
BACKGROUND: The payoff time represents an estimate of when the benefits of an intervention outweigh the costs. It is particularly useful for benefit-harm decision making for interventions that have deferred benefits but upfront harms. The aim of this study was to expand the application of the payoff time and provide an example of its use within a decision-analytic model. METHODS: Three clinically relevant patient vignettes based on varying levels of estimated 10-year cardiovascular risk (10%, 15%, 20%) were developed...
March 1, 2017: Medical Decision Making: An International Journal of the Society for Medical Decision Making
https://www.readbyqxmd.com/read/28440959/qualitative-research-in-teen-experiences-living-with-food-induced-anaphylaxis-a-meta-aggregation
#5
REVIEW
Sara F Johnson, Roberta L Woodgate
AIM: To describe the central experiences of teens living with Food-Induced Anaphylaxis as a first step in responding to health care needs in this population. BACKGROUND: As prevalence of allergy increases and commonly-outgrown allergies persist longer, chronic management for teens becomes increasingly important. This review seeks to understand how teens experience living with Food-Induced Anaphylaxis. DESIGN: Meta-aggregation for qualitative systematic review, to create synthesis for clinical improvement; guided by Joanna Briggs Institute methods and their Qualitative Assessment and Review Instrument...
April 25, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/28440827/molecular-dynamics-investigations-of-membrane-bound-cyp2c19-polymorphisms-reveal-distinct-mechanisms-for-peripheral-variants-by-long-range-effects-on-the-enzymatic-activity
#6
Ying-Lu Cui, Rong-Ling Wu
Increasing sophistication in methods used to account for human polymorphisms in susceptibility to drug metabolism has been one of the success stories in the prevention of adverse drug reactions. Genetic polymorphisms in drug-metabolizing enzymes can affect enzyme activity and cause differences in treatment response or drug toxicity. CYP2C19 is one of the most highly polymorphic CYP enzymes and acts on 10-15% of drugs in current clinical use. Despite the number of experimental analyses carried out for this system, the detailed structural basis for altered catalytic properties of polymorphic CYP2C19 variants remains unexplained at the atomic level...
April 25, 2017: Molecular BioSystems
https://www.readbyqxmd.com/read/28440782/systematization-of-clinical-trials-related-to-treatment-of-metabolic-syndrome-1980-2015
#7
Santiago Cardona Velásquez, Laura Guzmán Vivares, Jaiberth Antonio Cardona-Arias
INTRODUCTION: Despite the clinical, epidemiological, and economic significance of metabolic syndrome, the profile of clinical trials on this disease is unknown. OBJECTIVE: To characterize the clinical trials related to treatment of metabolic syndrome during the 1980-2015 period. METHODS: Systematic review of the literature using an ex ante search protocol which followed the phases of the guide Preferred Reporting Items for Systematic Reviews and Meta-Analyses in four multidisciplinary databases with seven search strategies...
February 2017: Endocrinol Diabetes Nutr
https://www.readbyqxmd.com/read/28440754/novel-aspects-in-histopathology-of-the-pituitary-gland
#8
Francisco Tortosa, Susan M Webb
The sellar and parasellar region is a complex anatomical area in which several diseases may develop. The pituitary gland may be affected by a wide range of conditions having similar clinical characteristics. Diagnosis of these lesions requires a multidisciplinary approach including, in addition to clinical, laboratory, imaging, and surgical findings, histological diagnosis of pituitary adenomas to guide therapeutic management. As the result of development in recent years of new immunohistochemical techniques, histopathological classification has become more complex and wide, and not only continues to be the gold standard in diagnosis, but also has prognostic implications...
March 2017: Endocrinol Diabetes Nutr
https://www.readbyqxmd.com/read/28440727/foam-sclerotherapy-of-the-great-saphenous-vein-in-association-with-pre-terminal-saphenous-junction-ligation-division-as-an-office-based-procedure-12-month-results
#9
Moro Leo, Ricci Stefano, Antonelli Incalzi Raffaele
Objective Ultrasound-guided foam sclerotherapy (UGFS) - one of the most frequently recommended methods for treating great saphenous vein incompetence - is easy and inexpensive. However, it achieves a lower occlusion rate compared to endovenous thermal ablation. The application of UGFS to pre-terminal great saphenous vein interruption, eliminating the saphenous stem wash out effect, enhances the short-term occlusion rate. This study explores the results of this technique at 12 months. Method Thirty great saphenous veins (28 patients) with junction incompetence, with calibres >6 mm and >30 cm reflux stem length were submitted to echo-guided pre-terminal great saphenous vein interruption and foam great saphenous vein occlusion...
January 1, 2017: Phlebology
https://www.readbyqxmd.com/read/28440543/registered-nurses-perceptions-regarding-nurse-led-antiretroviral-therapy-initiation-in-hhohho-region-swaziland
#10
A H Mavhandu-Mudzusi, P T Sandy, A Hettema
BACKGROUND: Swaziland has the highest HIV prevalence globally. It faces a critical shortage of health workers for addressing the HIV pandemic. To curb this human resource challenge, Swaziland adopted a nurse-driven model for antiretroviral therapy delivery in line with the recommendations of the World Health Organization on task shifting. OBJECTIVE: The study explored the perceptions of registered nurses on the nurse-led antiretroviral therapy initiation programme in the Hhohho region of Swaziland (NARTIS)...
April 25, 2017: International Nursing Review
https://www.readbyqxmd.com/read/28440325/multiparametric-mri-ultrasound-fusion-guided-biopsy-decreases-detection-of-indolent-cancer-in-african-american-men
#11
M Kongnyuy, M M Siddiqui, A K George, A Muthigi, A Sidana, M Maruf, B Turkbey, P L Choyke, B J Wood, P A Pinto
BACKGROUND: Analysis of systematic 12-core biopsies (SBx) has shown that African-American (AA) men tend to harbor higher risk prostate cancer (PCa) at presentation relative to other races. Multiparametric magnetic resonance imaging (mpMRI) and MRI-ultrasound fusion-guided biopsy (FBx) have been shown to diagnose more intermediate- and high-risk PCa in the general population; however, the efficacy in AA remains largely uncharacterized. We aim to evaluate the utility of FBx in an AA patient cohort...
April 25, 2017: Prostate Cancer and Prostatic Diseases
https://www.readbyqxmd.com/read/28440254/combined-branch-retinal-vein-and-branch-retinal-artery-occlusion-clinical-features-systemic-associations-and-outcomes
#12
Sabyasachi Sengupta, Utsab Pan
PURPOSE: Retinal vascular occlusions affecting both the arterial and venous systems are rare events. Combined branch retinal artery (BRAO) and vein (BRVO) occlusion are exceedingly rare and not well characterized. METHODS: Six patients with combined BRAO and BRVO underwent a comprehensive eye examination, fundus fluorescein angiography, optical coherence tomography, and cardiovascular evaluation. RESULTS: Mean age at presentation was 54 ± 7...
March 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28440239/feasibility-safety-and-outcomes-of-a-single-step-endoscopic-ultrasonography-guided-drainage-of-pancreatic-fluid-collections-without-fluoroscopy-using-a-novel-electrocautery-enhanced-lumen-apposing-self-expanding-metal-stent
#13
Joseph Yoo, Linda Yan, Raza Hasan, Saana Somalya, Jose Nieto, Ali A Siddiqui
BACKGROUND AND OBJECTIVES: There are currently limited data available regarding the safety of endoscopic ultrasound (EUS)-guided drainage of pancreatic fluid collections (PFCs) using the lumen-apposing metal stent without fluoroscopic guidance. This study aims to evaluate clinical outcomes and safety of EUS-guided drainage of PFC using the electrocautery-enhanced lumen-apposing metal stents (EC-LAMSs) without fluoroscopic guidance. METHODS: We conducted a retrospective study on patients with symptomatic PFC who underwent EUS-guided drainage using EC-LAMS without fluoroscopy...
March 2017: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/28440233/-clinical-cytology-for-endoscopists-a-practical-guide
#14
REVIEW
Michael Hocke, Theodoros Topalidis, Barbara Braden, Christoph F Dietrich
Clinical cytology was originally used by clinicians to provide rapid diagnosis. However, with advancing medical subspecialization, few clinicians interpret cytology themselves these days, for example, gynecologists, hematologists, urologists, and occasional gastroenterologist (mainly in Asian countries). Cytological assessment enjoyed a renaissance with the development of endoscopic ultrasound (EUS)-guided fine-needle aspiration (FNA). Subsequently, pathologists, most of them more experienced in histology, had to take over...
March 2017: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/28440232/clinical-use-of-endoscopic-ultrasound-guided-fine-needle-aspiration-guidelines-and-recommendations-from-chinese-society-of-digestive-endoscopy
#15
Nan Ge, Shutian Zhang, Zhendong Jin, Siyu Sun, Aiming Yang, Bangmao Wang, Guiqi Wang, Guoqiang Xu, Jianyu Hao, Liang Zhong, Ning Zhong, Peng Li, Qi Zhu, Weidong Nian, Wen Li, Xiaofeng Zhang, Xiaoping Zhou, Xiujiang Yang, Yi Cui, Zhen Ding
No abstract text is available yet for this article.
March 2017: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/28440098/early-diagnosis-of-amyotrophic-lateral-sclerosis-mimic-syndromes-pros-and-cons-of-current-clinical-diagnostic-criteria
#16
Elena Cortés-Vicente, Jesús Pradas, Juan Marín-Lahoz, Noemi De Luna, Jordi Clarimón, Janina Turon-Sans, Ellen Gelpí, Jordi Díaz-Manera, Isabel Illa, Ricard Rojas-Garcia
OBJECTIVE: To describe the frequency and clinical characteristics of patients referred to a tertiary neuromuscular clinic as having amyotrophic lateral sclerosis (ALS) but who were re-diagnosed as having an ALS mimic syndrome, and to identify the reasons that led to the revision of the diagnosis. METHODS: We reviewed the final diagnosis of all patients prospectively registered in the Sant Pau-MND register from 1 January 2004 to 31 December 2015. A detailed clinical evaluation and a clinically-guided electrophysiological study were performed at first evaluation...
April 25, 2017: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
https://www.readbyqxmd.com/read/28439625/-direct-mpr-a-useful-tool-for-oblique-ct-fluoroscopy-assisted-puncture
#17
Rui Sato, Takeshi Aramaki, Kiichiro Yoza, Kenji Iwai, Michihisa Moriguchi, Koiku Asakura, Masahiro Endo, Takahiro Ito
OBJECTIVE: Conventional multiplanar reconstruction (MPR) imaging can be used as a tool for planning oblique puncture procedures, but it takes a few minutes to reconstruct and is not appropriate for real-time CT fluoroscopy-assisted puncture. Recently, new MPR technology has been used that requires only 8 s and makes it possible to obtain a nearly real-time CT fluoroscopy-assisted oblique puncture. We refer to it as "direct MPR." This is the first clinical report of this technique. METHODS: Since February 2016, we have performed real-time, CT-guided oblique punctures with this new technology, "direct MPR," using an angio-CT system...
April 24, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28439618/-radiofrequency-current-or-cryoballoon-for-ablation-of-atrial-fibrillation-hot-or-cold
#18
B Reissmann, K-H Kuck, A Metzner
Atrial fibrillation (AF) is the most common form of cardiac arrhythmia. The aim of therapy in symptomatic patients is the establishment of a stable sinus rhythm (SR). Catheter ablation with isolation of the pulmonary veins is the essential component of all forms of ablation therapy and provides the most effective treatment option. The most frequently used technologies for pulmonary vein isolation (PVI) are radiofrequency current (RFC)-based and cryoballoon (CB)-guided ablation. Irrespective of the simplification of PVI, CB ablation is characterized by a short learning curve and short procedural times and demonstrated non-inferiority with respect to safety and efficacy when directly compared to RFC ablation for the treatment of patients with paroxysmal AF; however, the clinical outcome in patients with persistent AF is often insufficient when performing pulmonary vein isolation (PVI) alone for stabilization of SR...
April 24, 2017: Herz
https://www.readbyqxmd.com/read/28439532/recruiting-to-preclinical-alzheimer-s-disease-clinical-trials-through-registries
#19
Joshua D Grill
Participant registries are repositories of individuals who have expressed willingness to learn about studies for which they may be eligible. Registries are increasingly being utilized to improve recruitment to preclinical Alzheimer's disease (AD) clinical trials, which require large screening efforts to identify adequate numbers of participants who meet enrollment criteria. Recruiting to preclinical AD trials from registries is made more efficient through registry collection of data that permits exclusion of those who will not be eligible and identifies individuals most likely to qualify for trials...
June 2017: Alzheimer's & Dementia: Translational Research & Clinical Interventions
https://www.readbyqxmd.com/read/28439497/study-of-recombinant-human-interleukin-12-for-treatment-of-complications-after-radiotherapy-for-tumor-patients
#20
Na Guo, Wen-Qin Wang, Xiao-Jing Gong, Lei Gao, Li-Rong Yang, Wei-Na Yu, Hong-Yu Shen, Ling-Qin Wan, Xi-Feng Jia, Yi-Shan Wang, Yi Zhao
AIM: To evaluate the treatment effects of recombinant human interleukin-12 (rhIL-12) on radiotherapy complications, such as severe myelosuppression or pancytopenia, the decline or imbalance of immune function, etc. METHODS: The patients received high-dose and short-course precise radiotherapy, such as Cyber knife and image-guided radiotherapy (IGRT), which can cause myelosuppression or pancytopenia and immune function decline within a short time. One-hundred subjects were enrolled in the study, and 50 were randomized to a treatment group which used rhIL-12 and 50 were randomized to a control group which used symptomatic and supportive therapy after radiotherapy...
April 10, 2017: World Journal of Clinical Oncology
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