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Evelyn Fennelly, Marcus Lee, Mark Da Costa, Sherif Sultan, Faisal Sharif, Darren Mylotte
Transcatheter aortic valve implantation (TAVI) has emerged as the standard of care for older patients with symptomatic severe aortic stenosis (AS) at high or excessive operative risk. There remain patients that are of such considerable risk that even TAVI can be futile. Such patients present ethical conundrums for institutional heart teams. Herein we present a case of a 90-year-old female patient with symptomatic severe AS and significant comorbidities including diffuse peripheral vascular disease and a large ascending aortic aneurysm...
2018: Case Reports in Cardiology
Benjamin P d'S Murphy, Michelle M Dowsey, Peter F M Choong
BACKGROUND: Elective total hip arthroplasty (THA) and total knee arthroplasty (TKA) are effective options for the management of osteoarthritis that has not responded to conservative therapy, and they are increasing in utilization worldwide. Therefore, we sought to investigate how older age influences the outcomes of THA and TKA through a review of the current literature. METHODS: The Embase and MEDLINE databases were examined for relevant studies that assessed the role of older age in determining the outcomes of THA and TKA...
February 2018: JBJS Reviews
Vasileios D Tzilalis, Ioannis G Kantounakis, Konstantinos M Pirgakis, Antonios Ch Chalkias
No abstract text is available yet for this article.
February 19, 2018: European Journal of Cardio-thoracic Surgery
Wan-Ling Chen, Chin-Ming Chen, Shu-Chen Kung, Ching-Min Wang, Chih-Cheng Lai, Chien-Ming Chao
This retrospective cohort study investigated the outcomes and prognostic factors in nonagenarians (patients 90 years old or older) with acute respiratory failure. Between 2006 and 2016, all nonagenarians with acute respiratory failure requiring invasive mechanical ventilation (MV) were enrolled. Outcomes including in-hospital mortality and ventilator dependency were measured. A total of 173 nonagenarians with acute respiratory failure were admitted to the intensive care unit (ICU). A total of 56 patients died during the hospital stay and the rate of in-hospital mortality was 32...
January 23, 2018: Oncotarget
Yi Huang, Mark Rosenberg, Yingli Wang
Climate is closely related to human longevity. In China, there are many climate types. According to national population censuses from 1982 to 2000, most provinces with a high ratio of centenarians are located in western and northwestern China far from the sea; these areas are characterized by a dry, cold climate, very high altitude, very high daily temperature range, strong winds, and partial hypoxia. Meanwhile, provinces with a high ratio of nonagenarians from 1982 to 2000 are located in southern China near the sea...
February 17, 2018: International Journal of Biometeorology
Steven L Bokshan, Stephen E Marcaccio, Travis D Blood, Roman A Hayda
INTRODUCTION: Hip fractures account for a significant disease burden in the Unites States. With an aging population, this disease burden is expected to increase in the upcoming decades. MATERIALS AND METHODS: This represents a retrospective cohort study to assess mortality following hip fracture in the octogenarian and nonagenarian populations. Odds ratios for postoperative mortality were constructed using normalized patients from United States Social Security death tables...
February 6, 2018: Injury
Killugudi Jayaraman
No abstract text is available yet for this article.
February 7, 2018: Nature Medicine
Antonio Mauricio Dos Santos Cerqueira Junior, Luisa Gondim Dos Santos Pereira, Thiago Menezes Barbosa de Souza, Vitor Calixto de Almeida Correia, Felipe Kalil Beirão Alexandre, Gabriella Sant'Ana Sodré, Jessica Gonzalez Suerdieck, Felipe Ferreira, Marcia Maria Noya Rabelo, Luis Cláudio Lemos Correia
BACKGROUND: The GRACE Score was derived and validated from a cohort in which octogenarians and nonagenarians were poorly represented. OBJECTIVE: To test the accuracy of the GRACE score in predicting in-hospital mortality of very elderly individuals with acute coronary syndromes (ACS). METHODS: Prospective observational study conducted in the intensive coronary care unit of a tertiary center from September 2011 to August 2016. Patients consecutively admitted due to ACS were selected, and the very elderly group was defined by age ≥ 80 years...
February 1, 2018: Arquivos Brasileiros de Cardiologia
D Chivite, F Formiga
No abstract text is available yet for this article.
January 31, 2018: Revista Clínica Española
Motonori Nagasawa, Yoichi Takami, Hiroshi Akasaka, Mai Kabayama, Satomi Maeda, Serina Yokoyama, Taku Fujimoto, Yoichi Nozato, Yuki Imaizumi, Masao Takeda, Norihisa Itoh, Yasushi Takeya, Koichi Yamamoto, Ken Sugimoto, Takeshi Nakagawa, Yukie Masui, Yasumichi Arai, Tatsuro Ishizaki, Kazunori Ikebe, Yasuyuki Gondo, Kei Kamide, Hiromi Rakugi
AIM: The objective of the present study was to investigate the association between frailty and plasma adiponectin levels in a general population of Japanese older adults. METHODS: The volunteer older adults, aged approximately 83 years, were recruited randomly from a general population in the Japanese Septuagenarians, Octogenarians, Nonagenarians Investigation with Centenarians study. We used the modified Cardiovascular Health Study criteria to assess the frailty status of the study participants...
February 2, 2018: Geriatrics & Gerontology International
Julia Gerhardt, Stefanie Bette, Insa Janssen, Jens Gempt, Bernhard Meyer, Yu-Mi Ryang
OBJECTIVE: An increasing demographic aging of the general population results in a rising incidence of octo- and nonagenarians with spine disease. Patients over 65 years of age represent the majority of patients with degenerative lumbar spine disease in our daily clinical routine. Due to an increased rate of comorbidities indication for surgery is seen very reluctant. We therefore assessed complication rates of lumbar decompression with regard to neurological outcome, medical conditions in patients 80 years or older in a retrospective single center series...
January 29, 2018: World Neurosurgery
A Sudlow, H Tuffaha, A T Stearns, I A Shaikh
Introduction An increasing proportion of the population is living into their nineties and beyond. These high risk patients are now presenting more frequently to both elective and emergency surgical services. There is limited research looking at outcomes of general surgical procedures in nonagenarians and centenarians to guide surgeons assessing these cases. Methods A retrospective analysis was conducted of all patients aged ≥90 years undergoing elective and emergency general surgical procedures at a tertiary care facility between 2009 and 2015...
January 24, 2018: Annals of the Royal College of Surgeons of England
Ming Yang, Linlin Xie, Xiu Liu, Qiukui Hao, Jiaojiao Jiang, Birong Dong
Recent studies have revealed the prognostic role of the gamma gap, the total serum proteins concentration minus the albumin concentration, for predicting all-cause mortality among adults. This study aims to investigate the relationship between the gamma gap and all-cause mortality among nonagenarians and centenarians via a secondary data analysis of a prospective observational study. The analysis included 801 participants (260 men and 541 women, mean age: 93.7 ± 3.5 years), 46 of which were lost at the 4-year follow-up...
January 18, 2018: Scientific Reports
Richard J Cassidy, Xinyan Zhang, Jeffrey M Switchenko, Pretesh R Patel, Joseph W Shelton, Sibo Tian, Ronica H Nanda, Conor E Steuer, Rathi N Pillai, Taofeek K Owonikoko, Suresh S Ramalingam, Felix G Fernandez, Seth D Force, Theresa W Gillespie, Walter J Curran, Kristin A Higgins
BACKGROUND: To the authors' knowledge, the practice patterns for patients aged more than 80 years with stage III non-small cell lung cancer (NSCLC) is not well known. The purpose of the current study was to investigate factors predictive of and the impact on overall survival (OS) after concurrent chemoradiation (CRT) among patients aged ≥80 years with American Joint Committee on Cancer stage III NSCLC in the National Cancer Data Base (NCDB). METHODS: In the NCDB, patients aged ≥80 years who were diagnosed with stage III NSCLC from 2004 to 2013 with complete treatment records were identified...
January 8, 2018: Cancer
Luca Padua, Patrizio Pasqualetti, Daniele Coraci, Isabella Imbimbo, Alessandro Giordani, Claudia Loreti, Camillo Marra, Raffaello Molino-Lova, Guido Pasquini, Ilaria Simonelli, Federica Vannetti, Claudio Macchi
The population of industrialized nations is progressively aging, with Italy having one of the most elderly populations in the world. Natural aging may be associated with physical and cognitive impairments, often straining public resources. The present study aims to investigate the influence of gender on wellness of the nonagenarians. We evaluated quality of life among nonagenarians living in the Mugello area, an Italian location with a large population of individuals > 90 years, using the Health Survey Scoring SF-12...
January 8, 2018: Neurological Sciences
Doron Sagiv, Sahar Nadel, Yoav Pinhas Talmi, Ran Yahalom, Michael Wolf, Eran Emanuel Alon
PURPOSE: The admission rate of patients aged 80 years or older (oldest-old) with head and neck (HN) oncologic disease is on the rise. Our goal was to study the demographic characteristics, reasons for admission, types of surgical procedures, and postoperative complications of the oldest-old patients with HN malignancy. MATERIALS AND METHODS: We conducted a retrospective cohort study including all inpatients aged 80 years or older who were admitted to the department of otolaryngology-head and neck surgery or department of oral and maxillofacial surgery because of HN oncologic disease between 2009 and 2013...
December 7, 2017: Journal of Oral and Maxillofacial Surgery
Guglielmo Bonaccorsi, Chiara Lorini, Francesca Santomauro, Francesco Sofi, Federica Vannetti, Guido Pasquini, Claudio Macchi
OBJECTIVE: The aim is to describe the adherence to Mediterranean diet in a sample of nonagenarians and to analyse its cross-sectional association with anthropometric and bioelectrical parameters. DESIGN: A cross-sectional design was employed in this study. The adherence to the Mediterranean diet was measured through the Mediterranean Diet Score (MedDietScore). SETTING AND PARTICIPANTS: A representative sample of nonagenarian residents in the eight municipalities belonging to Mugello (Florence, Italy)...
December 20, 2017: Experimental Gerontology
Ming Yang, Hanyue Xu, Ling Yang, Jiaojiao Jiang, Birong Dong
BACKGROUND: Little is known about the relationship between metabolic syndrome (MetS) and disability in the oldest old. AIMS: To investigate the possible association between MetS and disability among community-dwelling older adults aged ≥ 90 years. METHODS: This was a secondary analysis of a cross-sectional study. MetS was defined by the International Diabetes Federation Criteria. Activities of daily living (ADL) and instrumental activities of daily living (IADL) disabilities were evaluated using the physical self-maintenance scale and the Lawton-Brody IADL scale, respectively...
December 12, 2017: Aging Clinical and Experimental Research
Rajat Sharma, Brett Hiebert, David Cheung, Davinder S Jassal, Kunal Minhas
The proportion of individuals >80 years of age constitute an increasing proportion of patients who present with ST-segment elevation myocardial infarction (STEMI). The objective of this study is to evaluate in-hospital outcomes and 1-year survival of very elderly patients who present with an STEMI and undergo primary percutaneous coronary intervention (pPCI). Between 2009 and 2015, individuals >80 years of age (very elderly patients) with an STEMI presenting at a single tertiary Canadian care center were included in the study...
January 1, 2017: Angiology
Anna Scelzo, Salvatore Di Somma, Paola Antonini, Lori P Montross, Nicholas Schork, David Brenner, Dilip V Jeste
OBJECTIVE: This was a study of positive psychological traits in a group of rural Italians aged 90 to 101 years, and their children or other family members. DESIGN: Mixed-methods quantitative (standardized rating scales) and qualitative (semi-structured interviews) study. SETTING: Study participants' homes in nine villages in the Cilento region of southern Italy. PARTICIPANTS: Twenty-nine nonagenarians and centenarians and 51 family members aged 51-75 years, selected by their general practitioners as a part of a larger study called CIAO (Cilento Initiative on Aging Outcomes)...
January 2018: International Psychogeriatrics
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