Francesco Torri, Emanuele Balzano, Fabio Melandro, Paolo Maremmani, Pietro Bertini, Paolo Lo Pane, Matilde Masini, Maria Isabella Rotondo, Serena Babboni, Serena Del Turco, Stefano Antonelli, Vincenzo De Tata, Giandomenico Biancofiore, Fabio Guarracino, Aldo Paolicchi, Paolo De Simone, Giuseppina Basta, Davide Ghinolfi
BACKGROUND: In Italy, 20 min of continuous, flat-line electrocardiogram are required for death declaration. Despite prolonged warm ischemia time, Italian centers reported good outcomes in controlled donation after circulatory death (cDCD) liver transplantation by combining normothermic regional and end-ischemic machine perfusion (MP). The aim of this study was to evaluate the safety and feasibility of the use of septuagenarian and octogenarian cDCD donors with this approach. METHODS: All cDCD older than 70 y were evaluated during normothermic regional perfusion and then randomly assigned to dual hypothermic or normothermic MP...
March 12, 2024: Transplantation