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Octogenarians

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https://www.readbyqxmd.com/read/28641971/comorbidities-have-a-greater-impact-than-age-alone-in-the-outcomes-of-octogenarian-total-knee-arthroplasty
#1
Kae Sian Tay, Eric W L Cher, Karen Zhang, Seang Beng Tan, Tet Sen Howe, Joyce S B Koh
BACKGROUND: Increasing age and various comorbidities are known risk factors for complications after total knee arthroplasty (TKA), but data on the impact of total comorbidity burden is scarce. We investigated the effect of age and total comorbidity burden on outcomes after primary TKA in octogenarians (OGs). METHODS: A matched-pair comparison study was conducted using prospectively collected TKA registry data in a large tertiary institution. Between 2006 and 2011, consecutive OGs undergoing primary unilateral TKA, with minimum 2-year follow-up, were matched 1:1 with younger controls based on demographic and surgical variables...
May 31, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28640791/octogenarian-liver-grafts-reaching-centennial-age-after-transplantation
#2
Luis Carlos Jiménez-Romero, Oscar Caso Maestro, Félix Cambra Molero, Alejandro Manrique Municio, Jorge Calvo Pulido, Alberto Marcacuzco Quinto, Iago Justo Alonso
No abstract text is available yet for this article.
July 2017: Transplantation
https://www.readbyqxmd.com/read/28633519/changes-in-abdominal-aortic-aneurysm-epidemiology
#3
Fredrik Lilja, Anders Wanhainen, Kevin Mani
INTRODUCTION: The epidemiology and treatment of abdominal aortic aneurysms (AAA) has changed over the past 30 years. EVIDENCE ACQUISITION: This review aims to give the reader an overview of these changes and current trends in AAA epidemiology, management and outcome. EVIDENCE SYNTHESIS: In the past decades there have been three changes in AAA management and epidemiology: a) introduction of endovascular aortic repair (EVAR), b) population screening and c) a markedly reduced prevalence of the disease...
June 20, 2017: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28618921/surgical-evacuation-of-acute-subdural-hematoma-in-octogenarians-a-ten-year-experience-from-a-single-trauma-centerfunding
#4
Michael J McGinity, Joel E Michalek, Jesse S Rodriguez, John R Floyd
BACKGROUND: Elderly patients presenting with an acute subdural hematoma (aSDH) have historically had unfavorable outcomes. METHODS: We retrospectively reviewed patient records from 2005 through 2015 that were ≥80 years of age and underwent surgical evacuation of aSDH. RESULTS: Thirty-four patients met inclusion criteria, with a mean age of 84 years (range 80-91). Glascow Outcome Scale (GOS) of 4-5 was deemed a good outcome and a GOS 1-3 was deemed to be a poor outcome...
June 15, 2017: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/28618883/the-freedom-of-the-octogenarian-to-find-grace-and-humor-in-the-lasting-personal-strength-gained-through-cappe-education
#5
Maureen Soukoreff
No abstract text is available yet for this article.
June 2017: Journal of Pastoral Care & Counseling: JPCC
https://www.readbyqxmd.com/read/28616346/emergent-aortic-surgery-in-octogenarians-is-the-advanced-age-a-contraindication
#6
REVIEW
Mario Castaño, Javier Gualis, Jose M Martínez-Comendador, Elio Martín, Pasquale Maiorano, Laura Castillo
Surgery of both the ascending and descending aortic segments in the context of an acute aortic syndrome is one of the greatest challenges for the cardiac surgeon. In the case of surgery of the descending aorta, surgical risk increases due to the technical complexity, the required aggressive approach and because surgical indication is usually established as a result of complications and therefore involves, almost always, critically ill patients. The aging of the population is causing such surgery to be considered in an increasing number of octogenarians...
May 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28614074/a-patient-not-alone
#7
Lauren Sydney Flicker
This case analysis examines questions that arise when an ethically appropriate recommendation initially appears to be in conflict with the legally appropriate recommendation. The case involves a dying, incapacitated octogenarian who had friends who were willing to share her values, but not to make decisions on her behalf. These circumstances put the patient in the unique position of being legally considered a "patient alone," but who was ethically like a patient with surrogates-distinctions that are crucial when making end-of-life decisions under the New York Family Health Care Decisions Act...
2017: Journal of Clinical Ethics
https://www.readbyqxmd.com/read/28608028/incidence-and-treatments-of-dcis-in-octogenarians-grade-matters
#8
Erin P Ward, Anna Weiss, Sarah L Blair
PURPOSE: The purpose of this study is to better characterize the current incidence and treatment patterns of DCIS in women greater than 80 years of age (>80) and to evaluate the effect of grade on treatment efficacy. METHODS: Retrospective observational study of women diagnosed with single primary DCIS from 2000 to 2012 in SEER. Statistics including incidence, multivariable Cox proportional hazards model and subset analysis were performed. RESULTS: 42,899 female patients with DCIS were identified, 2566 (5...
June 12, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28606075/comparison-of-the-surgical-outcomes-of-minimally-invasive-and-open-surgery-for-octogenarian-and-older-compared-to-younger-gastric-cancer-patients-a-retrospective-cohort-study
#9
Chien-An Liu, Kuo-Hung Huang, Ming-Huang Chen, Su-Shun Lo, Anna Fen-Yau Li, Chew-Wun Wu, Yi-Ming Shyr, Wen-Liang Fang
BACKGROUND: As life expectancy continues to increase around the world, the use of minimally invasive surgery (MIS) could be beneficial for octogenarian and older gastric cancer patients. METHODS: A total of 359 gastric cancer patients who underwent curative surgery between March 2011 and March 2015 were enrolled; 80 of these patients (22.2%) were octogenarians and older. Surgical approaches included MIS (50 laparoscopic and 65 robotic) and open surgery (n = 244)...
June 12, 2017: BMC Surgery
https://www.readbyqxmd.com/read/28603591/clinical-characteristics-and-outcomes-of-octogenarians-presenting-with-st-elevation-myocardial-infarction-in-the-australian-population
#10
Wei Liang Sim, Vivek Mutha, Muhammad Asrar Ul-Haq, Victoria Sasongko, William Van-Gaal
AIM: To investigate the characteristics and outcomes of octogenarians who presented with ST-elevation myocardial infarction (STEMI) compared to non-octogenarians and to investigate the outcomes of octogenarians that received primary percutaneous coronary intervention (PCI) compared to those managed conservatively. METHODS: We performed a single center retrospective case controlled study. All octogenarians who presented with STEMI to a tertiary referring hospital between 2007 and 2012 were included...
May 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/28600019/safety-and-efficacy-outcomes-of-second-generation-everolimus-eluting-stents-in-octogenarians-compared-to-non-octogenarians
#11
Hironori Kitabata, Takashi Kubo, Kazuya Mori, Yasunori Yamamoto, Manabu Kashiwagi, Yu Arita, Takashi Tanimoto, Takashi Akasaka
BACKGROUND: In patients ≥80 years of age, the use of second-generation cobalt-chromium everolimus-eluting stents (CoCr-EES) versus bare-metal stents has been shown to reduce myocardial infarction (MI) and target vessel revascularization (TVR) rates, without an increase in bleeding. However, safety and efficacy of CoCr-EES in octogenarians compared to younger populations are less certain. We aimed to compare the clinical outcomes between octogenarian and non-octogenarian patients undergoing percutaneous coronary intervention (PCI) with CoCr-EES...
June 1, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28597120/long-term-prognostic-implications-of-myocardial-perfusion-imaging-in-octogenarians-an-all-comer-cohort-study
#12
Athanasios Katsikis, Athanasios Theodorakos, Vassiliki Manira, Spyridon Papaioannou, Genovefa Kolovou, Vassilios Voudris, Maria Koutelou
PURPOSE: Evaluation of the long-term prognostic value of myocardial perfusion imaging (MPI) in octogenarians. METHODS: Six hundred and twenty-nine octogenarians [51% previous myocardial infarction (MI) or revascularization] who underwent single-isotope MPI (78% (201)Tl, 22% (99m)Tc-tetrofosmin) with exercise (38% Bruce, 2% leg ergometry) or pharmacologic (58% adenosine, 2% dobutamine) stress were studied. All patients had LVEF determined by echocardiography within 1 month from MPI...
June 8, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28595961/-flexible-bronchoscopy-in-octogenarians
#13
Antonio Noguera-Sánchez, María J Soler-Sempere, Justo Grau-Delgado, Lucía Zamora-Molina, Isabel Padilla-Navas, Eduardo García-Pachón
No abstract text is available yet for this article.
June 5, 2017: Revista Española de Geriatría y Gerontología
https://www.readbyqxmd.com/read/28582490/impact-of-minimally-invasive-extracorporeal-circuits-on-octogenarians-undergoing-coronary-artery-bypass-grafting-have-we-been-looking-in-the-wrong-direction-%C3%A2
#14
Aschraf El-Essawi, Ingo Breitenbach, Benjamin Haupt, Rene Brouwer, Hassina Baraki, Wolfgang Harringer
OBJECTIVES: Minimally invasive extracorporeal circuits (MiECCs) aim at the preservation of physiologic reserves, the impact of which is expected to be most evident in patients in whom these are depleted. In this context, octogenarians present a subpopulation of specific interest. METHODS: Based on the type of the utilized ECC, we performed a retrospective comparison between all octogenarians ( n  = 324) who received a primary coronary artery bypass in our institution from 2003 until 2010...
June 3, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28578624/outcomes-after-endovascular-revascularization-in-octogenarians-and-non-octogenarians-with-critical-limb-ischemia
#15
Theodosios Bisdas, Markus Steinbauer, Giovanni Torsello, Christian Uhl
PURPOSE: To determine the outcome and periprocedural risk of endovascular revascularization in octogenarians with critical limb ischemia (CLI) compared with their younger counterparts. METHODS: The multicenter, prospective registry for First-line Treatments in Patients With Critical Limb Ischemia (CRITISCH) enrolled 642 patients treated with endovascular techniques ( ClinicalTrials.gov identifier NCT01877252). The patients were dichotomized according to age <80 years (n=421; mean age 69 years, 292 men; group 1) or ≥80 years (n=221; mean age 85 years, 113 men; group 2)...
June 1, 2017: Journal of Endovascular Therapy
https://www.readbyqxmd.com/read/28566202/management-of-renal-masses-in-an-octogenarian-cohort-is-there-a-right-approach
#16
Dominic H Tang, Jude Nawlo, Juan Chipollini, Scott M Gilbert, Michael Poch, Julio M Pow-Sang, Wade J Sexton, Philippe E Spiess
BACKGROUND: We reviewed the outcomes for an octogenarian population to investigate whether active surveillance (AS) provides comparable survival to partial nephrectomy (PN) or radical nephrectomy (RN). PATIENTS AND METHODS: Data were collected from 115 octogenarian patients referred for management of renal masses at Moffitt Cancer Center from 2000 to 2013. Patients were treated with AS, PN, or RN. Univariable and multivariable Cox regression models measured the association between management modality and survival...
May 10, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/28542978/procedural-outcomes-and-long-term-survival-following-lead-extraction-in-octogenarians
#17
Mikhael F El-Chami, Michael N Sayegh, Adarsh Patel, Jad El-Khalil, Yaanik Desai, Angel R Leon, Faisal M Merchant
BACKGROUND: Octogenarians account for a significant percentage of patients with indwelling pacemakers or defibrillators. OBJECTIVES: To determine procedural outcomes and long-term survival after Lead Extraction (LE) in octogenarians. METHODS: We retrospectively identified all patients who underwent defibrillator or pacemaker LE at our institution between January 1(st) 2007 and May 31(st) 2016. Patients were stratified based on age into two groups: < 80 years old (Group 1, n = 674) or ≥ 80 (Group 2, n = 100)...
May 24, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28539544/postoperative-outcome-of-high-risk-octogenarians-undergoing-cardiac-surgery-a-multicenter-observational-retrospective-study
#18
Michal Porizka, Jan Kunstyr, Tomas Vanek, Michal Nejedly, Jana Buckova, Jiri Mokrejs, Frantisek Mosna
PURPOSE: Cardiac surgery in octogenarians with severely deteriorated functional status is increasingly common, but outcome data are still limited. The aim of this study was to compare postoperative outcome, survival, and quality of life of low-, medium-, and high-risk octogenarians undergoing cardiac surgery. METHODS: In all, 285 Czech octogenarians who underwent any cardiac surgical procedure between January 2011 and December 2012 were included in the study. Five out of all twelve national adult cardiac surgical centers participated in the study, representing almost half of all octogenarians operated in our country in that period...
May 24, 2017: Annals of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28533667/octogenarian-liver-grafts-is-their-use-for-transplant-currently-justified
#19
Carlos Jiménez-Romero, Felix Cambra, Oscar Caso, Alejandro Manrique, Jorge Calvo, Alejandro Marcacuzco, Paula Rioja, David Lora, Iago Justo
AIM: To analyse the impact of octogenarian donors in liver transplantation. METHODS: We present a retrospective single-center study, performed between November 1996 and March 2015, that comprises a sample of 153 liver transplants. Recipients were divided into two groups according to liver donor age: recipients of donors ≤ 65 years (group A; n = 102), and recipients of donors ≥ 80 years (group B; n = 51). A comparative analysis between the groups was performed...
May 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28529533/low-expression-of-cd39-and-cd73-genes-in-centenarians-compared-with-octogenarians
#20
Almudena Crooke, Juan Martínez-Henández, Joaquín Martínez-López, Alfonso Cruz-Jentoft, Fernando Huete-Toral, Jesús Pintor
Ageing involves a progressive decline of the body's regulatory systems including immune system. Adenosine regulates immune function by interaction with its receptors, mainly adenosine A2A receptor, present on the surface of immune cells. Furthermore, cellular response to this nucleoside is highly dependent on its extracellular concentration that is regulated by ecto-enzymes such as CD39 and CD73. Therefore, the aim of this study was to investigate the effect of age on adenosine A2A receptor, CD39 and CD73 gene expression...
2017: Immunity & Ageing: I & A
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