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Octogenarians

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https://www.readbyqxmd.com/read/28808869/hospitalizations-and-nursing-facility-stays-during-the-transition-from-ckd-to-esrd-on-dialysis-an-observational-study
#1
Maria E Montez-Rath, Yuanchao Zheng, Manjula Kurella Tamura, Vanessa Grubbs, Wolfgang C Winkelmayer, Tara I Chang
BACKGROUND: There is little information on hospital and nursing facility stays during the transition from pre-dialysis kidney disease to end-stage renal disease treated with dialysis. OBJECTIVES: To examine hospital and nursing facility stays in the years pre- and post-dialysis initiation, and to develop a novel method for visualizing these data. DESIGN: Observational study of patients in the US Renal Data System initiating dialysis from October 2011 to October 2012...
August 14, 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/28807220/health-characteristics-of-heart-transplant-recipients-surviving-into-their-80s
#2
Deborah R Tabachnick, Megan E Bowen, Josef Stehlik, Abdallah G Kfoury, William T Caine, Craig H Selzman, Stephen H McKellar
BACKGROUND: Heart transplantation (HTx) is the preferred treatment for patients with end-stage heart failure and has been successful for >30 y. The clinical course of recipients at the extreme of age is unknown. We reviewed our experience to determine the overall health and prevalence of Tx-related medical problems for recipients in their ninth decade. METHODS: We reviewed the UCTP experience from 1985 to present to identify patients who survived into their 80s and matched (1:1) with other recipients for gender and age at HTx, but did not survive to ≥80 y...
August 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28796770/what-is-the-relationship-between-visual-impairment-and-cognitive-function-in-octogenarians
#3
Denise S de Kok, Ruth O Teh, Avinesh Pillai, Martin J Connolly, Tim J Wilkinson, Simon A Moyes, Robert Jacobs, Marama Muru-Lanning, Anna Rolleston, Dieuwke Schiphof, Ngaire Kerse
AIMS: To examine direct and indirect pathways between visual and cognitive function in advanced age. METHODS: We analysed cross-sectional baseline data from Life and Living in Advanced Age: A Cohort Study in New Zealand, which recruited equal sample sizes of Māori (n=421) and non-Māori (n=516) octogenarians. The Modified Mini-Mental State Examination assessed cognitive function. Vision was assessed with self-report and measured distance visual acuity. Associations between visual and cognitive function were explored using general linear models and structural equation modelling...
August 11, 2017: New Zealand Medical Journal
https://www.readbyqxmd.com/read/28792681/long-term-outcome-of-renal-transplantation-from-octogenarian-donors-a-multicenter-controlled-study
#4
Piero Ruggenenti, Cristina Silvestre, Luigino Boschiero, Giovanni Rota, Lucrezia Furian, Annalisa Perna, Giuseppe Rossini, Giuseppe Remuzzi, Paolo Rigotti
To assess whether biopsy-guided selection of kidneys from very old brain-death donors enables more successful transplantations, this multicenter, observational study compared graft survival between 37 Recipients of one or two histologically evaluated kidneys from >80-years-old donors and 198 Reference-Recipients of non-histologically evaluated single grafts from ≤60-year-old donors (transplant period: 2006-2013 at three Italian Centers). Over a median (IQR) of 25 (13-42) months, two Recipients (5.4%) and 10 Reference-Recipients (5...
August 9, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28780975/short-term-and-long-term-results-of-endovascular-and-open-repair-of-abdominal-aortic-aneurysms-in-germany
#5
Christian-Alexander Behrendt, Art Sedrakyan, Henrik Christian Rieß, Franziska Heidemann, Tilo Kölbel, Jörg Petersen, Eike Sebastian Debus
BACKGROUND: Endovascular aortic repair (EVAR) has emerged as a standard of care for abdominal aortic aneurysm (AAA) repair. However, real-world evidence to compare this technology to open aortic repair (OAR) is limited. Major gaps exist related to long-term outcomes of therapies worldwide. METHODS: Health insurance claims data of Germany's third largest insurance provider, DAK-Gesundheit, were used to determine outcomes after interventions for intact AAA (iAAA) and ruptured AAA (rAAA)...
August 3, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28759121/health-care-disparities-among-octogenarians-and-nonagenarians-with-stage-ii-and-iii-rectal-cancer
#6
Richard J Cassidy, Jeffrey M Switchenko, En Cheng, Renjian Jiang, Jaymin Jhaveri, Kirtesh R Patel, Daniel G Tanenbaum, Maria C Russell, Conor E Steuer, Theresa W Gillespie, Mark W McDonald, Jerome C Landry
BACKGROUND: Octogenarians and nonagenarians with stage II/III rectal adenocarcinomas are underrepresented in the randomized trials that have established the standard-of-care therapy of preoperative chemoradiation followed by definitive resection (ie, chemoradiation and then surgery [CRT+S]). The purpose of this study was to evaluate the impact of therapies on overall survival (OS) for patients with stage II/III rectal cancers and determine predictors of therapy within the National Cancer Data Base (NCDB)...
July 31, 2017: Cancer
https://www.readbyqxmd.com/read/28756069/gliosarcoma-in-septuagenarians-and-octogenarians-what-is-the-impact-of-adjuvant-chemoradiation
#7
Jacob Y Shin, Ja Kyoung Yoon, Aidnag Z Diaz
The objective of our study is to determine the impact of adjuvant chemoradiation on overall survival (OS) for gliosarcoma in septuagenarians and octogenarians. Data were extracted from the National Cancer Data Base (NCDB). Chi-square test, Kaplan-Meier method, and Cox regression models were employed in SPSS 23.0 (Armonk, NY: IBM Corp.) for data analyses. 210 patients with gliosarcoma who underwent resection were identified. 168 (80.0%) patients received adjuvant chemoradiation, and 42 (20.0%) received adjuvant RT alone...
July 26, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28754532/centenarians-maintain-mirna-biogenesis-pathway-while-it-is-impaired-in-octogenarians
#8
C Borrás, E Serna, J Gambini, M Inglés, J Vina
Centenarians but not octogenarians up regulate the expression of miRNAs, as we previously reported. We have looked into miRNA biogenesis. We show that RNA POL II, DROSHA, EXPORTIN 5 and DICER, are up-regulated in centenarians compared with octogenarians. Furthermore, factors involved in the control of these miRNAs biogenesis genes are also up-regulated in centenarians. Therefore, the up-regulation of miRNA expression in centenarians can be explained in part because miRNA biogenesis pathway is depressed in octogenarians (ordinary aging) while it is maintained in centenarians (extraordinary aging)...
July 25, 2017: Mechanisms of Ageing and Development
https://www.readbyqxmd.com/read/28753853/survival-outcomes-in-octogenarian-and-nonagenarian-patients-treated-with-first-line-androgen-deprivation-therapy-for-organ-confined-prostate-cancer
#9
Paolo Dell'Oglio, Mohamed Bishr, Katharina Boehm, Vincent Trudeau, Alessandro Larcher, Zhe Tian, Josè Sosa, Marco Moschini, Fred Saad, Umberto Capitanio, Alberto Briganti, Markus Graefen, Francesco Montorsi, Pierre I Karakiewicz
BACKGROUND: The use of primary androgen deprivation therapy (PADT) is common in elderly men with early-stage prostate cancer (PCa), despite the absence of guideline recommendations. OBJECTIVE: To examine survival patterns of octo- and nonagenarian men with organ-confined PCa exposed to PADT, to assess whether their life expectancy warrants androgen deprivation therapy use. DESIGN, SETTING, AND PARTICIPANTS: In the Surveillance, Epidemiology, and End Results-Medicare-linked database, we identified 14 785 octo- and nonagenarian organ-confined PCa patients treated with PADT between 1991 and 2009...
February 11, 2017: European Urology Focus
https://www.readbyqxmd.com/read/28752182/the-challenging-surgical-treatment-of-closed-distal-humerus-fractures-in-elderly-and-octogenarian-patients-radiographic-and-functional-outcomes-with-a-minimum-follow-up-of-24%C3%A2-months
#10
Carlo Biz, Silvano Pierluigi Sperotto, Nicola Maschio, Matteo Borella, Claudio Iacobellis, Pietro Ruggieri
INTRODUCTION: The main purpose of this retrospective, non-randomized, case series study was to evaluate the clinical and radiographic outcomes of distal humerus fractures (DHFs) in a consecutive series of elderly patients operatively treated by two surgeons, and second, to identify proper indications for two elderly age ranges and two fracture pattern groups. MATERIALS AND METHODS: From January 2009 to June 2014, 51 patients (pts) underwent open reduction and internal fixation (ORIF) using the locking compression plate (LCP) distal humerus plate (DHP) system at our institution...
July 27, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28747024/clinical-profile-and-outcomes-in-octogenarians-with-atrial-fibrillation-a-community-based-study-in-a-specific-european-health-care-area
#11
Moisés Rodríguez-Mañero, Estrella López-Pardo, Alberto Cordero, Omar Kredieh, María Pereira-Vazquez, Jose-Luis Martínez-Sande, Alvaro Martínez-Gomez, Carlos Peña-Gil, José Novo-Platas, Javier García-Seara, Pilar Mazón, Ricardo Laje, Isabel Moscoso, Alfonso Varela-Román, Jose María García-Acuña, José Ramón González-Juanatey
BACKGROUND: Age increases risk of stroke and bleeding. Clinical trial data have had relatively low proportions of elderly subjects. We sought to study a Spanish population of octogenarians with atrial fibrillation (AF) by combining different sources of electronic clinical records from an area where all medical centres utilized electronic health record systems. METHODS: Data was derived from the Galician Healthcare Service information system. RESULTS: From 383,000 subjects, AF was coded in 7990 (2...
September 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28744971/predicted-factors-for-older-taiwanese-to-be-healthy-octogenarians-results-of-an-18-year-national-cohort-study
#12
Wei-Chung Hsu, Alan C Tsai, Yu-Chia Chen, Jiun-Yi Wang
AIM: To identify factors that predict the 62-69 years old Taiwanese to be healthy octogenarians. METHODS: We analyzed the 1989 (baseline), and 2003 and 2007 (end-point) datasets of the Taiwan Longitudinal Survey on Aging, a national cohort study. A total of 1977 participants aged 62-69 years at baseline were tracked for 14-18 years. The outcome measure was "being healthy octogenarians", defined as participants who were aged ≥80 years, free from activities of daily living dependency, depressive symptoms or cognitive impairment, and able to provide social support...
July 26, 2017: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/28744756/short-term-outcome-of-unicompartmental-knee-arthroplasty-in-the-octogenarian-population
#13
Baha John Tadros, John Dabis, Roy Twyman
PURPOSE: Unicompartmental knee arthroplasty (UKA) provides significant benefits to patients with anteromedial osteoarthritis, with good long-term results. Morbidity and mortality rates are lower, and recovery is quicker. These benefits would be advantageous to the octogenarian population whom carry significant comorbidities. The primary aim was to compare the short-term functional outcome at 2 years of UKA in the octogenarian population against a stratified younger cohort of patients...
July 25, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28743653/a-review-of-arterio-venous-fistulae-creation-in-octogenarians
#14
Jennifer Clarissa Diandra, Zhiwen Joseph Lo, Wei-Wen Ang, Jue Fei Feng, Sriram Narayanan, Glenn Wei Leong Tan, Sadhana Chandrasekar
BACKGROUND: To analyse the outcomes of arterio-venous fistulae (AVF) creation in Octogenarians. METHODS: Retrospective study of 47 AVFs created in patients aged 80 years and above from 2008 to 2014. Patient and AVF characteristics and outcomes were evaluated. Predictors of patency were analysed with multivariate analysis and Kaplan-Meier patency and survival analysis was performed. RESULTS: 47 of 1,259 AVFs created were for Octogenarians (4%)...
July 22, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28741196/how-safe-is-performing-cholecystectomy-in-the-oldest-old-a-15-year-retrospective-study-from-a-single-institution
#15
Matteo Novello, Davide Gori, Salomone Di Saverio, Matteo Bianchin, Lorenzo Maestri, Francesco Vito Mandarino, Giuseppe Cavallari, Bruno Nardo
BACKGROUND: Globally, the number of people aged 80 years or over, the "oldest old," is the fastest growing population group. Because of the strong association between age and gallstone disease, both prevalence and incidence of this disease are increasing. The feasibility of the cholecystectomy in octogenarians has been evaluated in several studies that confirmed the safety of the operation. However, the safety of this procedure in nonagenarians is still controversial. The aim of this study was to evaluate the safety of cholecystectomies in nonagenarians and identify related predictors for postoperative hospital length of stay (LOS) and in-hospital mortality up to 30 days postoperatively...
July 24, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28733076/-giant-congenital-cholesteatoma-in-an-octogenarian-patient
#16
Lucía Lozano Vicario, Joaquín Yanes Díaz, Jorge Manzarbeitia Arambarri, Enrique Antonio Durio Calero
No abstract text is available yet for this article.
July 18, 2017: Revista Española de Geriatría y Gerontología
https://www.readbyqxmd.com/read/28730759/surgical-treatment-for-colorectal-cancer-in-octogenarians-and-nonagenarians
#17
Young Wan Kim
Advances in surgical techniques and perioperative care have improved cancer-related outcomes. However, there are still concerns regarding the safety of octogenarian and nonagenarian patients during surgery. Clinicians may be reluctant to perform a radical resection for colorectal cancer and administer adjuvant or palliative cytotoxic chemotherapy to octogenarian and nonagenarian patients. In the elderly, setting a primary goal based on multidisciplinary team discussions prior to treatment is important. The overall treatment scheme, risks, and potential benefits should be discussed with elderly patients and their families...
May 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28728480/safety-and-efficacy-of-stenting-nonthrombotic-iliac-vein-lesions-in-octogenarians-and-nonagenarians-in-an-office-setting
#18
Pavel Kibrik, Justin Eisenberg, Ahmad Alsheekh, Syed Ali Rizvi, Afsha Aurshina, Natalie Marks, Anil Hingorani, Enrico Ascher
Objectives Treatment options for venous insufficiency are rapidly evolving in the office setting and include venography, intravascular ultrasound, and venous stenting. Non-thrombotic iliac vein lesions assessment and treatment in an office setting is currently an area of interest. The purpose of this study is to demonstrate the safety and efficacy of evaluating non-thrombotic iliac vein lesion with this office-based procedure in octogenarians and nonagenarians. Methods From January 2012 through December 2013, 300 non-thrombotic iliac vein lesion limbs in 192 patients with venous insufficiency ≥80 years old were evaluated for non-thrombotic iliac vein lesion...
January 1, 2017: Vascular
https://www.readbyqxmd.com/read/28718076/adenosine-mps-in-octogenarians-looking-safely-into-the-future
#19
EDITORIAL
Samantha Cliffe, Eliana Reyes
No abstract text is available yet for this article.
July 17, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28711225/-arsenic-pesticides-as-an-uncommon-cause-of-basal-cell-carcinoma-in-an-octogenarian-patient
#20
José Luis Agudo-Mena, José Manuel Azaña-Defez, Eva María García-Atienza, María Encarnación Gómez-Sánchez
No abstract text is available yet for this article.
July 12, 2017: Revista Española de Geriatría y Gerontología
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