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Hypertension older adult

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https://www.readbyqxmd.com/read/28339633/osmotic-indices-and-kidney-concentrating-activity-population-based-data-on-correlates-and-prognostic-power
#1
Massimo Cirillo, Giancarlo Bilancio, Cinzia Lombardi, Pierpaolo Cavallo, Oscar Terradura Vagnarelli, Alberto Zanchetti, Martino Laurenzi
Background.: Research data are limited on indices of osmotic equilibrium and of kidney concentrating activity (KCA). This study investigated correlates and prognostic power of these indices in a sample of the general population. Methods.: Urine osmolality (U-osm), plasma osmolality (P-osm), plasma creatinine and other variables were measured by the Gubbio Study for the 1988-92 exam (baseline). Plasma creatinine and other variables were re-measured in the 2001-07 exam (follow-up)...
February 4, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28338663/prevalence-and-associated-factors-of-blepharoptosis-in-korean-adult-population-the-korea-national-health-and-nutrition-examination-survey-2008-2011
#2
M H Kim, J Cho, D Zhao, K I Woo, Y-D Kim, S Kim, S W Yang
PurposeThis study aimed to evaluate the prevalence and associated factors of involutional blepharoptosis in a nationwide representative sample in Korea.MethodsCross-sectional study 20 941 Korean men and women 40 years of age and older who participated in last 2 years (2008 and 2009) of the 4th wave of the Korean National Health and Nutrition Examination Survey (KNHANES) IV and the first 2 years (2010 and 2011) of KNHANES V. Ocular examinations were performed by ophthalmologists trained in procedure and grading methods, and blepharoptosis was defined as a marginal reflex distance <2 mm on either eye...
March 24, 2017: Eye
https://www.readbyqxmd.com/read/28331214/antihypertensive-medications-and-the-risk-of-kidney-stones-in-older-adults-a-retrospective-cohort-study
#3
R Todd Alexander, Eric McArthur, Racquel Jandoc, Blayne Welk, Jade S Hayward, Arsh K Jain, Branko Braam, Veit Flockerzi, Amit X Garg, Robert Ross Quinn
Antihypertensives are widely prescribed and could influence kidney stone risk by altering urinary calcium excretion. However, the impact of different classes of antihypertensives on kidney stone risk is unknown. To assess this impact, we conducted a retrospective, population-based cohort study using linked health administrative databases. Individuals aged >65 years who initiated one of the four antihypertensive classes (that is, angiotensin-converting enzyme inhibitors (ACEis)/angiotensin receptor blockers (ARBs), beta-blockers, calcium channel blockers or thiazide diuretics) were included...
March 23, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28329840/a-multi-faceted-approach-to-promote-comprehension-of-online-health-information-among-older-adults
#4
Jessie Chin, Darcie D Moeller, Jessica Johnson, Elise A G Duwe, James F Graumlich, Michael D Murray, Daniel G Morrow
Purpose of the Study: Older adults' self-care often depends on understanding and utilizing health information. Inadequate health literacy among older adults poses a barrier to self-care because it hampers comprehension of this information, particularly when the information is not well-designed. Our goal was to improve comprehension of online health information among older adults with hypertension who varied in health literacy abilities. Design and Methods: We identified passages about hypertension self-care from credible websites (typical passages)...
March 10, 2017: Gerontologist
https://www.readbyqxmd.com/read/28329157/low-normalized-grip-strength-is-a-biomarker-for-cardiometabolic-disease-and-physical-disabilities-among-u-s-and-chinese-adults
#5
Mark D Peterson, Kate Duchowny, Qinqin Meng, Yafeng Wang, Xinxin Chen, Yaohui Zhao
Background: Evidence highlights the importance of muscular strength as a protective factor for health and function across aging populations. The purpose of this study was to examine the extent to which low normalized grip strength (NGS) serves as a biomarker for both cardiometabolic disease and physical disability in U.S. and Chinese adults. Methods: Middle aged and older adults from the U.S. National Health and Nutrition Examination Survey 2011-2012 and 2013-2014 combined surveys (n = 4,544), and the 2011 wave of the China Health and Retirement Longitudinal Study (n = 6,030) were included...
March 10, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28324763/interaction-of-apoe-e4-and-poor-glycemic-control-predicts-white-matter-hyperintensity-growth-from-73-to-76
#6
Simon R Cox, Stuart J Ritchie, David Alexander Dickie, Alison Pattie, Natalie A Royle, Janie Corley, Benjamin S Aribisala, Sarah E Harris, Maria Valdés Hernández, Alan J Gow, Susana Muñoz Maniega, John M Starr, Mark E Bastin, Joanna M Wardlaw, Ian J Deary
We examined whether apolipoprotein E (APOE) status interacts with vascular risk factors (VRFs) to predict the progression of white matter hyperintensities (WMHs) on brain MRI scans over a specific period of life in older age when the risk of dementia increases. At age 73 years, baseline VRFs were assessed via self-reported history of diabetes, hypertension, smoking, and hypercholesterolemia, and via objective measures of blood HbA1c, body mass index, diastolic and systolic blood pressure, and blood high-density lipoprotein to total cholesterol (HDL) ratio...
February 27, 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/28320601/coronary-atherosclerosis-in-indigenous-south-american-tsimane-a-cross-sectional-cohort-study
#7
Hillard Kaplan, Randall C Thompson, Benjamin C Trumble, L Samuel Wann, Adel H Allam, Bret Beheim, Bruno Frohlich, M Linda Sutherland, James D Sutherland, Jonathan Stieglitz, Daniel Eid Rodriguez, David E Michalik, Chris J Rowan, Guido P Lombardi, Ram Bedi, Angela R Garcia, James K Min, Jagat Narula, Caleb E Finch, Michael Gurven, Gregory S Thomas
BACKGROUND: Conventional coronary artery disease risk factors might potentially explain at least 90% of the attributable risk of coronary artery disease. To better understand the association between the pre-industrial lifestyle and low prevalence of coronary artery disease risk factors, we examined the Tsimane, a Bolivian population living a subsistence lifestyle of hunting, gathering, fishing, and farming with few cardiovascular risk factors, but high infectious inflammatory burden. METHODS: We did a cross-sectional cohort study including all individuals who self-identified as Tsimane and who were aged 40 years or older...
March 16, 2017: Lancet
https://www.readbyqxmd.com/read/28319592/trends-in-prevalence-awareness-treatment-and-control-of-high-blood-pressure-in-the-seychelles-between-1989-and-2013
#8
Samuel Heiniger, Bharathi Viswanathan, Jude Gedeon, Fred Paccaud, Pascal Bovet
BACKGROUND: Limited data are available in the African region on trends in blood pressure (BP) and awareness, treatment and control rates. OBJECTIVE: We examined trends in these indicators for a 25-year period in the Seychelles, a rapidly developing small island state in the African region. METHODS: Population-based surveys of adults aged 25-64 years were performed in 1989, 1994, 2004 and 2013 using nearly identical methods for all surveys...
March 17, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28314706/characteristics-and-outcomes-of-heart-failure-related-hospitalization-in-adults-with-congenital-heart-disease
#9
Nidhal Ben Moussa, Clement Karsenty, Florence Pontnau, Sophie Malekzadeh-Milani, Younes Boudjemline, Antoine Legendre, Damien Bonnet, Laurence Iserin, Magalie Ladouceur
BACKGROUND: Heart failure (HF) is the main cause of death in adult congenital heart disease (ACHD). AIMS: We aimed to characterize HF-related hospitalization of patients with ACHD, and to determine HF risk factors and prognosis in this population. METHODS: We prospectively included 471 patients with ACHD admitted to our unit over 24 months. Clinical and biological data and HF management were recorded. Major cardiovascular events were recorded for ACHD with HF...
March 14, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/28302553/stark-regional-and-sex-differences-in-the-prevalence-and-awareness-of-hypertension-an-h3africa-awi-gen-study-across-6-sites-in-sub-saharan-africa
#10
F Xavier Gómez-Olivé, Stuart A Ali, Felix Made, Catherine Kyobutungi, Engelbert Nonterah, Lisa Micklesfield, Marianne Alberts, Romuald Boua, Scott Hazelhurst, Cornelius Debpuur, Felistas Mashinya, Sekgothe Dikotope, Hermann Sorgho, Ian Cook, Stella Muthuri, Cassandra Soo, Freedom Mukomana, Godfred Agongo, Christopher Wandabwa, Sulaimon Afolabi, Abraham Oduro, Halidou Tinto, Ryan G Wagner, Tilahun Haregu, Alisha Wade, Kathleen Kahn, Shane A Norris, Nigel J Crowther, Stephen Tollman, Osman Sankoh, Michèle Ramsay
BACKGROUND: There is a high prevalence of hypertension and related cardiovascular diseases in sub-Saharan Africa, yet few large studies exploring hypertension in Africa are available. The actual burden of disease is poorly understood and awareness and treatment to control it is often suboptimal. OBJECTIVES: The study sought to report the prevalence of measured hypertension and to assess awareness and control of blood pressure among older adults in rural and urban settings in 6 sites located in West, East, and Southern Africa...
March 13, 2017: Global Heart
https://www.readbyqxmd.com/read/28300627/serum-uric-acid-is-associated-with-better-executive-function-in-men-but-not-in-women-baseline-assessment-of-the-elsa-brasil-study
#11
Cristina Pellegrino Baena, Claudia Kimie Suemoto, Sandhi Barreto, Paulo Lotufo, Isabela Benseñor
BACKGROUND: Serum uric acid (SUA) may protect against free radical stress damage and was previously linked to cognitive impairment in older adults, but evidence in middle-aged adults is scarce. PURPOSE: We sought to analyze whether SUA is associated with cognitive performance in apparently healthy middle-aged participants in the ELSA-Brasil cohort study. METHODS: We excluded participants older than age 65, those taking allopurinol, benzbromarone, or medications that could impair cognitive performance, those with previous stroke, and those with incomplete data on cognitive tests or SUA...
March 11, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28295858/non-obstructive-carotid-atherosclerosis-and-patent-foramen-ovale-in-young-adults-with-cryptogenic-stroke
#12
A Jaffre, B Guidolin, J-B Ruidavets, N Nasr, V Larrue
BACKGROUND AND PURPOSE: Up to 50% of ischaemic strokes in young adults are classified as cryptogenic despite extensive work-up. We sought to evaluate the prevalence of non-obstructive carotid atherosclerosis (NOCA) and its association with patent foramen ovale (PFO) in young adults with cryptogenic stroke (CS). METHODS: Patients aged 18-54 years, consecutively treated for first-ever CS in an academic stroke service, were included. NOCA was assessed using carotid ultrasound examination and was defined as carotid plaque with <50% stenosis...
March 15, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28294372/alcohol-and-cardiovascular-disease-in-the-geriatric-population
#13
REVIEW
Aditi Kalla, Vincent M Figueredo
There has been little focus on the effects of alcohol on the elderly. Although the cardiovascular benefits of moderate alcohol consumption could be of the greatest benefit in this group, so might be the detrimental effects of abuse. In this article, we review available data on the effects of alcohol consumption on cardiovascular disease, cardiomyopathy, arrhythmias, hypertension, and vascular function in older adults. Alcohol consumption has increased in the US population age 65 years and older in the last decade, as has monthly heavy episodic drinking in older alcohol consumers...
March 10, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28293775/inflammatory-status-and-uricaemia-determine-hdl-cholesterol-levels-in-hypertensive-adults-over-65-an-analysis-of-the-fapres-register
#14
María Amparo Quintanilla, Mariano Andrés, Eliseo Pascual, Vicente Pallarés, Lorenzo Fácila, Pedro Morillas
In inflammatory disease, the levels of high-density lipoprotein cholesterol (HDL-C) decrease, and the composition of HLD-C changes. Data from the "non-inflammatory" general population indicate the presence of the same phenomenon, albeit to a smaller extent. Levels of uricaemia contribute to the overall inflammatory state of patients. The aim of this study was to analyse the association between inflammatory state, levels of uricaemia, and levels of HLD-C in a hypertensive Spanish population aged 65 or older...
March 14, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28292314/association-between-blood-lead-and-blood-pressure-a-population-based-study-in-brazilian-adults
#15
Ana Carolina Bertin de Almeida Lopes, Ellen Kovner Silbergeld, Ana Navas-Acien, Rachel Zamoiski, Airton da Cunha Martins, Alissana Ester Iakmiu Camargo, Mariana Ragassi Urbano, Arthur Eumann Mesas, Monica Maria Bastos Paoliello
BACKGROUND: Environmental lead exposure among adults may increase blood pressure and elevate the risk of hypertension. The availability of data on blood lead levels (BLL) in adult Brazilian population is scarce and population-based studies are important for screening the population exposure and also to evaluate associations with adverse health effects. The goal of this study was to examine the association of BLL with blood pressure and hypertension in a population-based study in a city in Southern Brazil...
March 14, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/28291625/systolic-diastolic-hypertension-versus-isolated-systolic-hypertension-and-incident-heart-failure-in-older-adults-insights-from-the-cardiovascular-health-study
#16
Apostolos Tsimploulis, Helen M Sheriff, Phillip H Lam, Daniel J Dooley, Markus S Anker, Vasilios Papademetriou, Ross D Fletcher, Charles Faselis, Gregg C Fonarow, Prakash Deedwania, Michel White, Miroslava Valentova, Marc R Blackman, Maciej Banach, Charity J Morgan, Kannayiram Alagiakrishnan, Richard M Allman, Wilbert S Aronow, Stefan D Anker, Ali Ahmed
BACKGROUND: Isolated systolic hypertension (ISH) is common in older adults and is a risk factor for incident heart failure (HF). We examined the association of systolic-diastolic hypertension (SDH) with incident HF and other outcomes in older adults. METHODS: In the Cardiovascular Health Study (CHS), 5776 community-dwelling adults≥65years had data on baseline systolic and diastolic blood pressure (SBP and DBP). We excluded those with DBP<60mmHg (n=821), DBP≥90 and SBP<140mmHg (n=28), normal BP, taking anti-hypertensive drugs (n=1138), normal BP, not taking anti-hypertensive drugs, history of hypertension (n=193), and baseline HF (n=101)...
March 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28289478/cerebral-white-matter-hyperintensities-on-mri-and-acceleration-of-epigenetic-aging-the-atherosclerosis-risk-in-communities-study
#17
Abhay Raina, Xiaoping Zhao, Megan L Grove, Jan Bressler, Rebecca F Gottesman, Weihua Guan, James S Pankow, Eric Boerwinkle, Thomas H Mosley, Myriam Fornage
BACKGROUND: Cerebral white matter hyperintensities (WMH) on magnetic resonance imaging (MRI) are part of the spectrum of brain vascular injury accompanying aging and are associated with a substantial risk of stroke and dementia. We investigated the association of cerebral WMH burden on MRI with a DNA methylation-based biomarker of aging, termed DNA methylation age acceleration, which represents the deviation of the DNA methylation-predicted age from the chronologic age. RESULTS: In this cross-sectional observational study of 713 African-American participants of the Atherosclerosis Risk in Communities study, aged 51-73 years, estimates of predicted age were obtained based on two algorithms (Hannum et al...
2017: Clinical Epigenetics
https://www.readbyqxmd.com/read/28285211/ovarian-serous-cystadenoma-with-ectopic-adrenal-tissue-in-a-65-year-old-patient-a-case-report
#18
Çağdaş Şahin, Enes Taylan, Ali Akdemir, Osman Zekioglu, Parvane Seyidova, Ahmet Mete Ergenoglu
INTRODUCTION: Ectopic adrenal tissue is a very rare entity in adult females, especially in the ovary, and is generally diagnosed incidentally during surgery. Although it can present at various sites during childhood, it becomes atrophic by adulthood due to normally functioning adrenal glands. Patients are predominantly asymptomatic; however, in some cases endocrine symptoms such as hypertension and fasciotruncal obesity due to hormonal activity can be seen or neoplastic transformation can appear...
February 27, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28284097/cardiovascular-risk-factors-and-risk-of-incident-depression-throughout-adulthood-among-men-the-johns-hopkins-precursors-study
#19
Nicole M Armstrong, Lucy A Meoni, Michelle C Carlson, Qian-Li Xue, Karen Bandeen-Roche, Joseph J Gallo, Alden L Gross
BACKGROUND: Modifiable cardiovascular risk factors elevate risk of subsequent depression in older adults, but the effect of their onset before or after age 65 on incident depression is unclear. METHODS: Participants were 1190 male medical students without a diagnosis of depression, who matriculated in 1948-1964 and followed through 2011. Cox proportional hazards models were used to assess associations of vascular risk-factor burden, diabetes, hypertension, hyperlipidemia, smoking status, and overweight/obese status with onset of incident depression...
March 6, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28279499/tadalafil-in-idiopathic-or-heritable-pulmonary-arterial-hypertension-pah-compared-to-pah-associated-with-connective-tissue-disease
#20
Nazzareno Galiè, Christopher P Denton, Fabio Dardi, Alessandra Manes, Gaia Mazzanti, Baohui Li, Lucio Varanese, Anne Esler, Cathi Harmon, Massimiliano Palazzini
BACKGROUND: The primary objective of this post hoc analysis was to evaluate clinical outcomes of tadalafil in patients with pulmonary arterial hypertension (PAH) associated with connective tissue disease (CTD-PAH) compared with patients with idiopathic/heritable PAH (I/H-PAH) for primary and key secondary efficacy endpoints, and safety. This analysis included adult patients with CTD-PAH or I/H-PAH who participated in the PHIRST and PHIRST-2 studies. METHODS: Patients were randomized 1:1:1:1:1 to tadalafil (2...
February 22, 2017: International Journal of Cardiology
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