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Hypertension older adult

Chen-Wei Pan, Deng-Juan Qian, Hong-Peng Sun, Qinghua Ma, Yong Xu, E Song
Purpose. To determine the prevalence, causes, and associations of visual impairment (VI) among participants aged 60 years or older in a rural community in China. Methods. A community-based survey was undertaken in a rural town located in Eastern China and 4579 people aged 60 years or older participated in the study. Presenting visual acuity was assessed using a Snellen chart with tumbling-E optotypes and anterior segment was examined using a slit-lamp. VI was defined as presenting VA <6/18 and it included moderate VI (<6/18 to 6/60) and blindness (<6/60)...
2016: Journal of Ophthalmology
Joanna Kostka, Tomasz Kostka, Ewa Borowiak
BACKGROUND: The goal of this study was to assess the physical activity (PA) and its determinants of older people living in the three different environments. METHODS: Three equal (n=693 each) groups of individuals aged ≥65 years living in urban, rural and institutional environments took part in this study. PA was measured by the Seven-Day Recall PA Questionnaire (energy expenditure - PA-EE) and the Stanford Usual Activity Questionnaire (health-related behaviors - PA-HRB)...
October 24, 2016: Journal of Physical Activity & Health
Nizal Sarrafzadegan, Mojgan Gharipour, Masoumeh Sadeghi, Pouya Nezafati, Mohammad Talaie, Shahram Oveisgharan, Fatemeh Nouri, Alireza Khosravi
BACKGROUND: Metabolic syndrome (MetS) is recently proposed as a predictor for the occurrence of vascular defects causing ischemic stroke. However, details on the association of MetS with stroke are scare in our region. The present study aimed to assess the predictive value of MetS and its components for stoke among the Iranian population. METHODS: A longitudinal population-based study was conducted on adults aged 35 years or older who were living in 3 districts in central part of Iran and followed for 10 years...
October 18, 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
Silvana B Sandbakk, Javaid Nauman, Nina Zisko, Øyvind Sandbakk, Nils Petter Aspvik, Dorthe Stensvold, Ulrik Wisløff
OBJECTIVE: To determine whether meeting physical activity (PA) recommendations and/or having high age-specific cardiorespiratory fitness (CRF) attenuate the adverse effect of prolonged sedentary time on cardiovascular risk factor (CV-RF) clustering in older adults. PATIENTS AND METHODS: We conducted a cross-sectional study of Norwegian women (495) and men (379) aged 70 to 77 years from August 22, 2012, through June 30, 2013. Sedentary time and PA were assessed by accelerometers and CRF by directly measured peak oxygen uptake (VO2peak)...
October 8, 2016: Mayo Clinic Proceedings
Andrea Gruneir, Lauren E Griffith, Kathryn Fisher, Dilzayn Panjwani, Sima Gandhi, Li Sheng, Chris Patterson, Amiram Gafni, Jenny Ploeg, Maureen Markle-Reid
OBJECTIVE: To characterize comorbid chronic conditions, describe health services use, and estimate health care costs among community-dwelling older adults with prior stroke. METHODS: This is a retrospective cohort study using administrative data from Ontario, Canada. We identified all community-dwelling individuals aged 66 and over on April 1, 2008 (baseline), who had experienced a stroke at least 6 months prior. We estimated the prevalence of 14 comorbid conditions at baseline; we captured all physician visits, emergency department visits, hospital admissions, home care contacts, and associated costs over 5 years stratifying by number of comorbid conditions...
October 19, 2016: Neurology
Hyun Min Kim, Jong-Mi Seong, Jaetaek Kim
The objective of this study was to carry out a large population-based study to understand the factors associated with hypoglycemia-related hospitalizations among older Korean adults with diabetes mellitus.This study analyzed data from a subset of the 2013 Health Insurance and Review and Assessment service-Adult Patient Sample. A total of 307,170 subjects, comprising 41.7% men and 58.3% women, had diabetes mellitus. Hypertension (80.8%) was the most common comorbidity, and dyslipidemia (59.0%) and ischemic heart disease (21...
October 2016: Medicine (Baltimore)
Tanmay Mahapatra, Kaushik Chakraborty, Sanchita Mahapatra, Umakanta Mahapatra, Naren Pandey, Peter L Thomson, Arthur W Musk, Ramendra N Mitra
BACKGROUND: Progressive burden of diabetes mellitus is a major concern in India. Data on the predictors of poor glycemic control among diabetics are scanty. A population-based cross-sectional study nested in an urban cohort was thus conducted in West Bengal, India to determine the burden and correlates of total and uncontrolled abnormalities in glucose metabolism (AGM) in a representative population. METHODS: From 9046 adult cohort-members, 269 randomly selected consenting subjects (non-response = 7...
2016: PloS One
Lee Mozessohn, Craig Earle, David Spaner, Stephanie Y Cheng, Matthew Kumar, Rena Buckstein
BACKGROUND: Metabolic syndrome (MetS) is a risk factor for development of cancer. Because aberrant lipid metabolism is a pathogenic feature of chronic lymphocytic leukemia (CLL), our objective was to determine if CLL patients have a higher prevalence of MetS preceding diagnosis and to determine the impact of lipid-lowering medications on survival. METHODS: We conducted a population-based case-control study in Ontario, Canada, using administrative databases of adults age 66 years and older to compare the prevalence of MetS preceding CLL with age- and sex-matched control subjects...
March 2017: Journal of the National Cancer Institute
Adriana Van Ballegooijen
Cardiovascular disease and osteoporosis are major age-related causes of morbidity and premature death that occur among older adults. Emerging evidence suggests that calcium from bone is deposited in the arteries. This leads to calcification in valves and vessels, which is associated with a 3-4 fold higher risk of coronary heart disease. Calcium and vitamin D supplementation is frequently advised in older adults for the prevention of osteoporosis and to reduce the risk of fractures and falls. However, recent RCT's showed that individuals taking calcium and vitamin D were at higher risk of cardiovascular disease...
September 2016: Journal of Hypertension
Paul Whelton
BACKGROUND: Choice of the optimal target for blood pressure (BP) reduction during treatment of patients with hypertension, including those with underlying co-morbid conditions, is an important challenge in clinical practice. The Systolic Blood Pressure Intervention Trial (SPRINT) was designed to provide guidance in selection of a Systolic BP target during treatment of hypertension. METHODS: Adults ≥50 years old with hypertension and at least one additional risk factor for cardiovascular disease (CVD), but excluding persons with diabetes mellitus, prior stroke, or advanced chronic kidney disease (CKD) were randomly assigned to intensive therapy (intensive), targeting a systolic BP (SBP) <120 mmHg, or standard therapy (standard), targeting a SBP <140 mmHg...
September 2016: Journal of Hypertension
Adrian Noriega De La Colina, Rong Wu, Laurence Desjardins-Crépeau, Pierre Larochelle, Maxime Lamarre-Cliche, Louis Bherer, Hélène Girouard
OBJECTIVE: The objective of this study was to assess cognitive performance in older adults treated and controlled for blood pressure (BP) when compared to untreated normotensive subjects, and to determine whether blood pressure still correlates with poorer cognitive performances. DESIGN AND METHOD: Forty-eight older adults aged between 65 and 85 years were recruited in the community and divided into two groups: normotensive (n = 26) and controlled hypertensive (n = 22)...
September 2016: Journal of Hypertension
Kristi Reynolds, Daichi Shimbo, C Barrett Bowling, Luqin Deng, Adam Bress, John Sim, Paul Muntner
OBJECTIVE: To identify risk factors for serious fall injuries following initiation of antihypertensive medication among older adults. DESIGN AND METHOD: We conducted a retrospective cohort study using a 5% random sample of people with Medicare health insurance, a government program for older US adults. The analysis was restricted to patients with a diagnosis of hypertension who initiated antihypertensive medication between 2007 and 2011. Initiation was defined by the first antihypertensive medication fill in this time period preceded by 365 days with no antihypertensive medication fills...
September 2016: Journal of Hypertension
Hiromi Rakugi
European guidelines (ESH-ESC2013) for the elderly have discussed well about treatment blood pressure (BP) levels and targeting BP levels. In general, elderly patients with systolic BP (SBP) ≥160 mmHg including individuals older than 80 years in good physical and mental conditions are recommended reducing SBP to between 150 and 140 mmHg. Furthermore, fit elderly patients <80 years old are recommended to consider antihypertensive treatment at SBP values ≥140 mmHg with a target SBP <140 mmHg. On the other hand, frail elderly patients are recommended to leave decisions on antihypertensive therapy to the treating physician, and based on monitoring of the clinical effects of treatment...
September 2016: Journal of Hypertension
Kwang-Il Kim
With the life-expectancy increased, the older population expected to grow all around the world. Especially, the increase of elderly population leads to increase of vulnerable or frail elderly people, who require special consideration in caring and managing chronic medical condition. Considering the substantial diversity in the prevalence of chronic medical conditions and functional impairment, elderly people are often highly heterogeneous and their physiological ability and vulnerability vary widely even in same chronological age...
September 2016: Journal of Hypertension
Adriana Van Ballegooijen, Natasja Van Schoor, Ingeborg Brouwer, Marjolein Visser, Joline Beulens
OBJECTIVE: Vitamin D plays an important role in calcium homeostasis. The role of vitamin D in bone and cardiovascular health has mainly been studied in isolation and the synergistic effect of vitamin D and vitamin K is largely unknown. We assessed whether serum 25-hydroxyvitamin D [25(OH)D] levels and dephosphorylated, uncarboxylated matrix Gla protein (dp-unMGP) levels -an established marker of vitamin K status- are associated with incident hypertension among older adults in the Netherlands...
September 2016: Journal of Hypertension
Xiongjing Jiang
Abdominal aortic aneurysm (AAA) is an important cause of mortality in older adults. Most AAAs are asymptomatic and screening programs have been introduced to identify AAAs. There is currently some recommendations for medical optimisation of patients with AAA, such as anti-hypertension, statin, Anti-platelet therapy, B-blockade, et al. Some medical treatments to limit progression of small AAAs, which have examined the potential of targeting inflammation, proteolysis, the renin-angiotensin system, the coagulation system and sex hormones as approaches to limiting AAA pathogenesis are investigated as well as...
September 2016: Journal of Hypertension
Tazeen Jafar
Chronic kidney disease (CKD) defined as reduced estimated glomerular filtration rate (eGFR) or presence of albuminuria, progresses to end stage renal disease (ESRD), needing dialysis or kidney transplant to sustain life, and is associated with increased risks of premature cardiovascular disease (CVD) and mortality. CKD ranked 18 leading (and most rapidly rising cause of mortality by the Global Burden of Disease Study 2010. The social and economic consequences of CKD are far worse in low and middle income countries (LMICs) including India, Pakistan, Bangladesh, and Sri Lanka...
September 2016: Journal of Hypertension
Eve Normandin, Elizabeth Chmelo, Mary F Lyles, Anthony P Marsh, Barbara J Nicklas
PURPOSE: The prevalence of metabolic syndrome is greatest in older obese adults and effective evidence-based treatment strategies are lacking. This study determined the efficacy of adding caloric restriction (CR) for weight loss to resistance training (RT) on metabolic syndrome (MetS) and its individual components in older overweight and obese adults. METHODS: We performed a 5-month randomized controlled trial in 126 older (65-79 yrs) overweight and obese (Body Mass Index: 27-35 kg/m) men and women who were assigned to progressive 3-d/wk, moderate-intensity RT with (RT+CR) or without caloric restriction (RT)...
October 13, 2016: Medicine and Science in Sports and Exercise
Olga Perelshtein Brezinov, Shaye Kivity, Shlomo Segev, Yechezkel Sidi, Ilan Goldenberg, Elad Maor, Robert Klempfner
Men tend to develop cardiovascular disease (CVD) earlier in life than women. Whether this difference is attributable only to gender is a matter of debate. The purpose of this study was to evaluate gender differences in cardiovascular risk in a large cohort of asymptomatic men and women and explore gender-related risk in prespecified risk factor subgroups. We investigated 14,966 asymptomatic men and women free of diabetes, hypertension, or ischemic heart disease who were annually screened. The primary end point of the present study was the occurrence of ischemic or cerebrovascular disease as composite end point...
August 30, 2016: American Journal of Cardiology
Wilson Nadruz, Dalane Kitzman, Beverly Gwen Windham, Anna Kucharska-Newton, Kenneth Butler, Priya Palta, Michael E Griswold, Lynne E Wagenknecht, Gerardo Heiss, Scott D Solomon, Hicham Skali, Amil M Shah
BACKGROUND: The contribution of cardiovascular dysfunction to frailty in older adults is uncertain. This study aimed to define the relationship between frailty and cardiovascular structure and function, and determine whether these associations are independent of coexisting abnormalities in other organ systems. METHODS: We studied 3,991 older adults (mean age 75.6±5.0 years; 59% female) from the Atherosclerosis Risk in Communities (ARIC) Study in whom the following six organ systems were uniformly assessed: cardiac (by echocardiography), vascular (by ankle-brachial-index and pulse-wave-velocity), pulmonary (by spirometry), renal (by estimated glomerular filtration rate), hematologic (by hemoglobin), and adipose (by body mass index and bioimpedance)...
October 12, 2016: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
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