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Hypertension older adult

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https://www.readbyqxmd.com/read/27906837/different-impacts-of-hypertension-and-diabetes-mellitus-on-all-cause-and-cardiovascular-mortality-in-community-dwelling-older-adults-the-rancho-bernardo-study
#1
Jee-Young Oh, Matthew A Allison, Elizabeth Barrett-Connor
OBJECTIVES: Although the prevalence rates of hypertension (HTN) and diabetes mellitus are slowing in some high-income countries, HTN and diabetes mellitus remain as the two major risk factors for atherosclerotic cardiovascular disease (CVD), the leading cause of death in the United States and worldwide. We aimed to observe the association of HTN and diabetes mellitus with all-cause and CVD mortality in older white adults. METHODS: All community-dwelling Rancho Bernardo Study participants who were at least 55 years old and had carefully measured blood pressure and plasma glucose from 75-g oral glucose tolerance test at the baseline visit (1984-1987, n = 2186) were followed up until death or the last clinic visit in 2013 (median 14...
January 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/27903588/discovery-and-validation-of-agonistic-angiotensin-receptor-autoantibodies-as-biomarkers-of-adverse-outcomes
#2
Peter Abadir, Alka Jain, Laura Powell, Qian-Li Xue, Jing Tian, Robert G Hamilton, David Bennett, Thomas Finucane, Jeremy D Walston, Neal S Fedarko
BACKGROUND: -Agonistic angiotensin II type I receptor autoantibodies (AT1RaAbs) have not been associated with functional measures or risk for adverse health outcomes. AT1RaAbs could be utilized to stratify patient risk and to identify patients who can benefit from angiotensin receptor blocker (ARB) treatment. METHODS: -Demographic and physiologic covariates were measured in a discovery set of community dwelling adults from Baltimore (N=255) and AT1RaAb associations with physical function tests and outcomes assessed...
November 30, 2016: Circulation
https://www.readbyqxmd.com/read/27901275/peripheral-nerve-blocks-for-the-treatment-of-headache-in-older-adults-a-retrospective-study
#3
Jacob R Hascalovici, Matthew S Robbins
OBJECTIVE: The objective of this study is to provide demographical and clinical descriptions of patients age 65 years old and older who were treated with peripheral nerve blocks (PNBs) at our institution and evaluate the safety and efficacy of this treatment. BACKGROUND: Headache disorders are common, disabling chronic neurological diseases that often persist with advancing age. Geriatric headache management poses unique therapeutic challenges because of considerations of comorbidity, drug interactions, and adverse effects...
November 30, 2016: Headache
https://www.readbyqxmd.com/read/27900515/community-based-healthy-aging-interventions-for-older-adults-with-arthritis-and-multimorbidity
#4
Janice C Zgibor, Lei Ye, Robert M Boudreau, Molly B Conroy, Joni Vander Bilt, Elizabeth A Rodgers, Elizabeth A Schlenk, Mini E Jacob, Jane Brandenstein, Steven M Albert, Anne B Newman
Examine the impact of programs led by community health workers on health and function in older adults with arthritis and other health conditions. We conducted a cluster-randomized trial of the Arthritis Foundation Exercise Program (AFEP) enhanced with the "10 Keys"™ to Healthy Aging compared with the AFEP program at 54 sites in 462 participants (mean age 73 years, 88 % women, 80 % white). Trained Community health workers delivered the 10-week programs. Outcomes assessed after 6 months included physical performance [Short Physical Performance Battery (SPPB)], Western Ontario and McMaster Universities (WOMAC) Osteoarthritis Index, and preventive health behaviors...
November 29, 2016: Journal of Community Health
https://www.readbyqxmd.com/read/27897610/effect-of-calcitriol-supplementation-on-blood-pressure-in-older-adults
#5
Jaime Alberto Bricio-Barrios, Alín Jael Palacios-Fonseca, Mario Del Toro-Equihua, Carmen Alicia Sanchez-Ramirez
Recent studies suggest that vitamin D plays an important role in the control of blood pressure. Unfortunately, because older adults are more likely to have low 25-hydroxyvitamin-D [25(OH)D] levels, this study investigated whether calcitriol supplementation reduces blood pressure in older adults with hypertension. The design was a double-blind placebo-controlled randomized clinical trial with 36 randomly assigned subjects (71.7 ± 10 years). Blood pressure and serum levels of 25(OH)D before and after calcitriol intervention (1,000 IU daily for 6 weeks; n = 22) or placebo (n = 23) for 6 weeks were analyzed...
October 2016: Journal of Nutrition in Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27896854/decreased-graft-survival-in-liver-transplant-recipients-of-donors-with-positive-blood-cultures-a-review-of-the-unos-dataset
#6
Moises A Huaman, Valery Vilchez, Xiaonan Mei, Malay B Shah, Michael F Daily, Jonathan Berger, Roberto Gedaly
Liver transplantation using blood culture positive donors (BCPD) has allowed a significant expansion of the donor pool. We aimed to characterize BCPD and assess the outcomes of BCPD liver transplant recipients. We retrieved data from the United Network for Organ Sharing (UNOS) registry on all adults who underwent primary, single organ deceased-donor liver transplantation in the U.S. between 2008 and 2013. Patients were classified in two cohorts: the BCPD cohort and the non-BCPD cohort. One-year graft and patient survival were compared between cohorts using Kaplan-Meier estimates and Cox models...
November 29, 2016: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/27893045/association-of-3-different-antihypertensive-medications-with-hip-and-pelvic-fracture-risk-in-older-adults-secondary-analysis-of-a-randomized-clinical-trial
#7
Rachel Puttnam, Barry R Davis, Sara L Pressel, Paul K Whelton, William C Cushman, Gail T Louis, Karen L Margolis, Suzanne Oparil, Jeffrey Williamson, Alokananda Ghosh, Paula T Einhorn, Joshua I Barzilay
Importance: On the basis of observational studies, the use of thiazide diuretics for the treatment of hypertension is associated with reduced fracture risk compared with nonuse. Data from randomized clinical trials are lacking. Objective: To examine whether the use of thiazide diuretics for the treatment of hypertension is associated with reduced fracture risk compared with nonuse. Design, Setting, and Participants: Using Veterans Affairs and Medicare claims data, this study examined hip and pelvic fracture hospitalizations in Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial participants randomized to first-step therapy with a thiazide-type diuretic (chlorthalidone), a calcium channel blocker (amlodipine besylate), or an angiotensin-converting enzyme inhibitor (lisinopril)...
November 21, 2016: JAMA Internal Medicine
https://www.readbyqxmd.com/read/27893041/a-comparison-of-the-prevalence-of-dementia-in-the-united-states-in-2000-and-2012
#8
Kenneth M Langa, Eric B Larson, Eileen M Crimmins, Jessica D Faul, Deborah A Levine, Mohammed U Kabeto, David R Weir
Importance: The aging of the US population is expected to lead to a large increase in the number of adults with dementia, but some recent studies in the United States and other high-income countries suggest that the age-specific risk of dementia may have declined over the past 25 years. Clarifying current and future population trends in dementia prevalence and risk has important implications for patients, families, and government programs. Objective: To compare the prevalence of dementia in the United States in 2000 and 2012...
November 21, 2016: JAMA Internal Medicine
https://www.readbyqxmd.com/read/27892612/the-prevalence-of-depressive-symptoms-among-older-patients-with-hypertension-in-rural-china
#9
Jiang Xue, Shulin Chen, Hillary R Bogner, Wan Tang, Lydia Li, Yeates Conwell
OBJECTIVE: The comorbidity of depression and hypertension (HTN) is common and complicates the management of both conditions. This study investigated the prevalence of depressive symptoms among older patients with HTN in rural China and explored the relationship between the two conditions. METHODS: The baseline data of older patients diagnosed with HTN included in the depression/HTN in Chinese Older Adults-Collaborations for Health Study were used for the analysis...
November 28, 2016: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/27890975/prevalence-of-type-2-diabetes-mellitus-among-urban-sikh-population-of-amritsar
#10
Amrinder Singh, Shweta Shenoy, Jaspal Singh Sandhu
CONTEXT: Type 2 Diabetes Mellitus (T2DM) refers to a group of common metabolic disorders that share the phenotype of Hyperglycemia. More than 60% of the world's population with diabetes comes from Asia. AIM: To study the prevalence of Type 2 Diabetes Mellitus among Sikh individuals living in the urban localities of Amritsar. SETTINGS AND DESIGN: The study was designed in the Faculty of Sports Medicine & Physiotherapy, Guru Nanak Dev University, Amritsar, Punjab, India...
October 2016: Indian Journal of Community Medicine
https://www.readbyqxmd.com/read/27884579/number-of-daily-antihypertensive-drugs-and-the-risk-of-osteoporotic-fractures-in-older-hypertensive-adults-national-health-insurance-service-senior-cohort
#11
So Yeon Kim, Sunyoung Kim, Sung Eun Choi, Byung Sung Kim, Hyun Rim Choi, Deri Hwang, Chang Won Won
BACKGROUND: Antihypertensive medication represents one of the most common prescriptions for senior individuals. Numerous studies have assessed the influence of antihypertensive treatment on the risk for osteoporotic fracture, yet much controversy remains. We analyzed the relationship between the incidence of osteoporotic fracture and the average number of daily antihypertensive drugs (NDAD) included in the prescription of elderly hypertensive patients. METHODS: The study population was derived from the National Health Insurance Service-Senior Cohort (2002-2013), and consisted of elderly patients (≥60 years) diagnosed with hypertension in 2009, who did not have osteoporotic fractures in 2008, and underwent at least one national health check-up between 2009 and 2013, and had complete records after 2010...
November 21, 2016: Journal of Cardiology
https://www.readbyqxmd.com/read/27880832/chronic-low-calorie-sweetener-use-and-risk-of-abdominal-obesity-among-older-adults-a-cohort-study
#12
Chee W Chia, Michelle Shardell, Toshiko Tanaka, David D Liu, Kristofer S Gravenstein, Eleanor M Simonsick, Josephine M Egan, Luigi Ferrucci
INTRODUCTION: Low-calorie sweetener use for weight control has come under increasing scrutiny as obesity, especially abdominal obesity, remain entrenched despite substantial low-calorie sweetener use. We evaluated whether chronic low-calorie sweetener use is a risk factor for abdominal obesity. PARTICIPANTS AND METHODS: We used 8268 anthropometric measurements and 3096 food diary records with detailed information on low-calorie sweetener consumption in all food products, from 1454 participants (741 men, 713 women) in the Baltimore Longitudinal Study of Aging collected from 1984 to 2012 with median follow-up of 10 years (range: 0-28 years)...
2016: PloS One
https://www.readbyqxmd.com/read/27876047/effects-of-longitudinal-changes-in-charlson-comorbidity-on-prognostic-survival-model-performance-among-newly-diagnosed-patients-with-hypertension
#13
Peter Rymkiewicz, Pietro Ravani, Brenda R Hemmelgarn, Finlay A McAlister, Danielle A Southern, Robin Walker, Guanmin Chen, Hude Quan
BACKGROUND: To assess the use of updated comorbidity information over time on ability to predict mortality among adults with newly diagnosed hypertension. METHODS: We studied adults 18 years and older with an incident diagnosis of hypertension from Alberta, Canada. We compared the prognostic performance of Cox regression models using Charlson comorbidities as time-invariant covariates at baseline (TIC) versus models including Charlson comorbidities as time-varying covariates (TVC) using Akaike Information Criterion (AIC) for testing goodness of fit...
November 22, 2016: BMC Health Services Research
https://www.readbyqxmd.com/read/27876016/incidence-and-risk-of-hypertension-in-patients-newly-treated-for-multiple-myeloma-a-retrospective-cohort-study
#14
Ajai Chari, Khalid Mezzi, Shao Zhu, Winifred Werther, Diana Felici, Alexander R Lyon
BACKGROUND: Hypertension is commonly reported in multiple myeloma (MM) patients and may be associated with older age, disease-related complications and consequences of MM treatments. This study evaluated the incidence rates of and risk factors for hypertension and malignant hypertension in newly-treated MM patients in the United States. METHODS: Newly-treated adult MM patients were identified from Truven MarketScan claims database from 1/1/05 to 3/31/14. Inclusion criteria were new diagnosis of MM with start of MM treatment, ≥12 months continuous enrollment prior to diagnosis, ≥30 days of continuous enrollment following initial diagnosis, and prescription drug coverage...
November 22, 2016: BMC Cancer
https://www.readbyqxmd.com/read/27874274/differential-association-between-sarcopenia-and-metabolic-phenotype-in-korean-young-and-older-adults-with-and-without-obesity
#15
You-Cheol Hwang, In-Jin Cho, In-Kyung Jeong, Kyu Jeung Ahn, Ho Yeon Chung
OBJECTIVE: To determine whether sarcopenia was associated with metabolic phenotype in subjects with and without obesity. METHODS: A total of 6,021 participants (2,592 men, 3,429 women) aged 30 to 93 years were assessed using data from the 2009 Korea National Health and Nutrition Examination Survey. Sarcopenia was defined as appendicular skeletal muscle mass divided by weight (%) that is <1 SD below the sex-specific mean for young adults. Metabolically unhealthy was defined as ≥2 components of metabolic syndrome or the presence of hypertension, diabetes, or cardiovascular disease...
November 22, 2016: Obesity
https://www.readbyqxmd.com/read/27874179/association-between-chewing-difficulty-and-symptoms-of-depression-in-adults-results-from-the-korea-national-health-and-nutrition-examination-survey
#16
Hye-Sun Shin, Yong-Soon Ahn, Do-Seon Lim
OBJECTIVES: To assess the association between chewing difficulty and symptoms of depression in a representative sample of the Korean population. DESIGN: Cross-sectional. SETTING: Korea National Health and Nutrition Examination Survey (KNHANES). PARTICIPANTS: KNHANES participants (N = 5,158). MEASUREMENTS: Chewing difficulty was assessed according to the self-reported presence of chewing problems using a structured questionnaire...
November 22, 2016: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/27872756/prevalence-of-hypertension-and-its-associated-risk-factors-among-34-111-haart-na%C3%A3-ve-hiv-infected-adults-in-dar-es-salaam-tanzania
#17
Marina Njelekela, Alfa Muhihi, Akum Aveika, Donna Spiegelman, Claudia Hawkins, Catharina Armstrong, Enju Liu, James Okuma, Guerino Chalamila, Sylvia Kaaya, Ferdinand Mugusi, Wafaie Fawzi
Background. Elevated blood pressure has been reported among treatment naïve HIV-infected patients. We investigated prevalence of hypertension and its associated risk factors in a HAART naïve HIV-infected population in Dar es Salaam, Tanzania. Methods. A cross-sectional analysis was conducted among HAART naïve HIV-infected patients. Hypertension was defined as systolic blood pressure (SBP) ≥ 140 mmHg and/or diastolic blood pressure (DBP) ≥ 90 mmHg. Overweight and obesity were defined as body mass index (BMI) between 25...
2016: International Journal of Hypertension
https://www.readbyqxmd.com/read/27870298/health-effects-of-short-term-fluctuations-in-macroeconomic-conditions-the-case-of-hypertension-for-older-americans
#18
Marco Angrisani, Jinkook Lee
We investigate the health effects of short-term macroeconomic fluctuations as described by changes in unemployment rate, house, and stock market price indexes. The 'Great Recession' provides the opportunity to conduct this analysis as it involved contemporaneous shocks to the labor, housing, and stock markets. Using panel data from the Health and Retirement Study over the period 2004-2010, we relate changes in hypertension status to changes in state-level unemployment rate and house prices and to changes in stock market prices...
November 2016: Health Economics
https://www.readbyqxmd.com/read/27869500/lower-frailty-is-associated-with-successful-cognitive-aging-among-older-adults-with-hiv
#19
Lindsay Mk Wallace, Maria Ferrara, Thomas D Brothers, Sara Garlassi, Susan A Kirkland, Olga Theou, Stefano Zona, Cristina Mussini, David J Moore, Kenneth Rockwood, Giovanni Guaraldi
BACKGROUND: Aging with HIV poses unique and complex challenges, including avoidance of neurocognitive disorder. Our objective here is to identify the prevalence and predictors of successful cognitive aging (SCA) in sample of older adults with HIV. METHODS: One hundred three HIV-infected individuals aged 50 and older were recruited from the Modena HIV Metabolic Clinic in Italy. Participants were treated with combination antiretroviral therapy (cART) for at least one year and had suppressed plasma HIV viral load...
November 21, 2016: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/27858854/prevalence-and-associated-factors-of-retinal-vein-occlusion-in-the-korean-national-health-and-nutritional-examination-survey-2008-2012-a-cross-sectional-observational-study
#20
Yong Un Shin, Heeyoon Cho, Jong Min Kim, Kunho Bae, Min Ho Kang, Jae Pil Shin, Eunwoo Nam, Se Woong Kang
Retinal vein occlusion (RVO) is the second most common retinal vascular diseases and there are only a few Asian population-based studies with small samples. Hypertension is one of a modifiable risk factor of RVO, but no recent studies have shown the relationship between RVO and hypertension control status. We aimed to investigate the prevalence of RVO and its associated factors in an adult Korean population.A nationwide population-based, cross-sectional study. We enrolled 37,982 participants from the Korea National Health and Nutrition Examination Survey who were 19 years or older and who had undergone ophthalmologic exams from 2008 through 2012...
November 2016: Medicine (Baltimore)
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