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https://www.readbyqxmd.com/read/28549648/characterization-of-long-term-gait-deficits-in-mouse-dmcao-using-the-catwalk-system
#1
E Caballero-Garrido, J C Pena-Philippides, Z Galochkina, E Erhardt, T Roitbak
Evaluation of functional outcome is widely used across species to assess the recovery process following various pathological conditions, including spinal cord injury, musculo-skeletal injury, mithochondrial disease, neuropathic cancer, Huntington's disease, chronic pain, cortical lesion, and olivocerebellar degeneration among others. The Stroke Therapy Academic Industry Roundtable (STAIR) recommends multiple endpoints for behavioral studies in pre-clinical stroke research, to demonstrate their clinical relevance...
May 23, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28521791/exploring-the-role-of-socioeconomic-factors-in-the-development-and-spread-of-anti-malarial-drug-resistance-a-qualitative-study
#2
Philip Emeka Anyanwu, John Fulton, Etta Evans, Timothy Paget
BACKGROUND: Malaria remains a global health issue with the burden unevenly distributed to the disadvantage of the developing countries of the world. Poverty contributes to the malaria burden as it has the ability to affect integral aspects of malaria control. There have been renewed efforts in the global malaria control, resulting in reductions in the global malaria burden over the last decade. However, the development of resistance to artemisinin-based combination therapy threatens the sustainability of the present success in malaria control...
May 18, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28497868/person-centred-care-dialectics-inquired-in-the-context-of-palliative-care
#3
Joakim Öhlén, Sheryl Reimer-Kirkham, Barbara Astle, Cecilia Håkanson, Joyce Lee, Marjukka Eriksson, Richard Sawatzky
Although a widely used concept in health care, person-centred care remains somewhat ambiguous. In the field of palliative care, person-centred care is considered a historically distinct ideal and yet there continues to be a dearth of conceptual clarity. Person-centred care is also challenged by the pull of standardization that characterizes much of health service delivery. The conceptual ambiguity becomes especially problematic in contemporary pluralistic societies, particularly in the light of continued inequities in healthcare access and disparities in health outcomes...
May 12, 2017: Nursing Philosophy: An International Journal for Healthcare Professionals
https://www.readbyqxmd.com/read/28496375/revisiting-the-etiological-aspects-of-dissociative-identity-disorder-a-biopsychosocial-perspective
#4
REVIEW
Vedat Şar, Martin J Dorahy, Christa Krüger
Dissociative identity disorder (DID) is a chronic post-traumatic disorder where developmentally stressful events in childhood, including abuse, emotional neglect, disturbed attachment, and boundary violations are central and typical etiological factors. Familial, societal, and cultural factors may give rise to the trauma and/or they may influence the expression of DID. Memory and the construction of self-identity are cognitive processes that appear markedly and centrally disrupted in DID and are related to its etiology...
2017: Psychology Research and Behavior Management
https://www.readbyqxmd.com/read/28485300/gait-studies-for-a-quadrupedal-microrobot-reveal-contrasting-running-templates-in-two-frequency-regimes
#5
Benjamin Goldberg, Neel Doshi, Kaushik Jayaram, Robert J Wood
Performance metrics such as speed, cost of transport, and stability are the driving factors behind gait selection in legged locomotion. To help understand the effect of gait on the performance and dynamics of small-scale ambulation, we explore four quadrupedal gaits over a wide range of stride frequencies on a 1.43 g, biologically-inspired microrobot, the Harvard Ambulatory MicroRobot (HAMR). Despite its small size, HAMR can precisely control leg frequency, phasing, and trajectory, making it an exceptional platform for gait studies at scales relevant to insect locomotion...
June 15, 2017: Bioinspiration & Biomimetics
https://www.readbyqxmd.com/read/28418696/eccentric-exercise-kinesiology-tape-and-balance-in-healthy-men
#6
Simona Hosp, Ramona Folie, Robert Csapo, Michael Hasler, Werner Nachbauer
CONTEXT:   Deficits in balance have been identified as a possible risk factor for knee injuries in athletes. Despite a lack of evidence for its effectiveness, kinesiology tape (KT) is widely used to prevent knee injuries. OBJECTIVE:   To investigate the influence of KT at the knee joint on balance ability in healthy men after eccentric exercise. DESIGN:   Crossover study. SETTING:   University laboratory. PATIENTS OR OTHER PARTICIPANTS:   Twelve young men with no history of lower limb injury volunteered for the study (age = 23...
April 18, 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/28401689/progressive-resistance-training-prt-improves-rheumatoid-arthritis-outcomes-a-district-general-hospital-dgh-model
#7
Klara Morsley, Berna Berntzen, Lisa Erwood, Toby Bellerby, Lyn Williamson
OBJECTIVE: Rheumatoid cachexia is common in rheumatoid arthritis (RA) patients and develops soon after diagnosis, despite adequate drug therapy. It is associated with multiple adverse effects on body composition, function and mortality. Progressive resistance training (PRT) improves these outcomes but is not widely prescribed outside of a research setting. The aim of the present study was to explore the practicality and effectiveness of providing PRT to patients in a district general hospital within the constraints of existing resources...
April 12, 2017: Musculoskeletal Care
https://www.readbyqxmd.com/read/28371740/the-high-cost-of-swing-leg-circumduction-during-human-walking
#8
K Alex Shorter, Amy R Wu, Arthur D Kuo
Humans tend to walk economically, with preferred step width and length corresponding to an energetic optimum. In the case of step width, it is costlier to walk with either wider or narrower steps than normally preferred. Wider steps require more mechanical work to redirect the body's motion laterally with each step, but the cost for narrower steps remains unexplained. Here we show that narrow steps are costly because they require the swing leg to be circumducted around the stance leg. Healthy adults (N=8) were tested walking with varying levels of circumduction, induced through lightweight, physical obstructions ("Fins") attached medially to the lower legs, during treadmill walking at fixed speed (1...
March 23, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28355648/the-health-of-european-populations-introduction-to-the-special-supplement-on-the-2014-european-social-survey-ess-rotating-module-on-the-social-determinants-of-health
#9
Jason Beckfield, Mirza Balaj, Courtney L McNamara, Tim Huijts, Clare Bambra, Terje A Eikemo
This introduction summarizes the main findings of the Supplement 'Social inequalities in health and their determinants' to the European Journal of Public Health. The 16 articles that constitute this supplement use the new ESS (2014) health module data to analyze the distribution of health across European populations. Three main themes run across these articles: documentation of cross-national variation in the magnitude and patterning of health inequalities; assessment of health determinants variation across populations and in their contribution to health inequalities; and the examination of the effects of health outcomes across social groups...
February 1, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/28296958/interaction-between-the-oculomotor-and-postural-systems-during-a-dual-task-compensatory-reductions-in-head-sway-following-visually-induced-postural-perturbations-promote-the-production-of-accurate-double-step-saccades-in-standing-human-adults
#10
Mathieu Boulanger, Guillaume Giraudet, Jocelyn Faubert
Humans routinely scan their environment for useful information using saccadic eye movements and/or coordinated movements of the eyes and other body segments such the head and the torso. Most previous eye movement studies were conducted with seated subject and showed that single saccades and sequences of saccades (e.g. double-step saccades) made to briefly flashed stimuli were equally accurate and precise. As one can easily appreciate, most gaze shifts performed daily by a given person are not produced from a seated position, but rather from a standing position either as subjects perform an action from an upright stance or as they walk from one place to another...
2017: PloS One
https://www.readbyqxmd.com/read/28291178/comparison-of-single-intra-articular-injection-of-novel-hyaluronan-hya-joint-plus-with-synvisc-one-for-knee-osteoarthritis-a-randomized-controlled-double-blind-trial-of-efficacy-and-safety
#11
RANDOMIZED CONTROLLED TRIAL
Shu-Fen Sun, Chien-Wei Hsu, Huey-Shyan Lin, I-Hsiu Liou, Yin-Han Chen, Chia-Ling Hung
BACKGROUND: Viscosupplementation has been widely used for the treatment of knee osteoarthritis. Because we found no well-controlled trial comparing single-injection regimens of hyaluronan for knee osteoarthritis, we compared the efficacy and safety of a single intra-articular injection of a novel cross-linked hyaluronan (HYA-JOINT Plus) with a single injection of Synvisc-One in patients with knee osteoarthritis. METHODS: In a prospective, randomized, controlled, double-blind trial with a 6-month follow-up, 132 patients with knee osteoarthritis (Kellgren-Lawrence grade 2 or 3) were randomized to receive 1 intra-articular injection of 3 mL of HYA-JOINT Plus (20 mg/mL) (n = 66) or 6 mL of Synvisc-One (8 mg/mL) (n = 66)...
March 15, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28269388/testing-the-assumption-of-normality-in-body-sway-area-calculations-during-unipedal-stance-tests-with-an-inertial-sensor
#12
Kyoung Jae Kim, Jennifer Lucarevic, Christopher Bennett, Ignacio Gaunaurd, Robert Gailey, Vibhor Agrawal
The quantification of postural sway during the unipedal stance test is one of the essentials of posturography. A shift of center of pressure (CoP) is an indirect measure of postural sway and also a measure of a person's ability to maintain balance. A widely used method in laboratory settings to calculate the sway of body center of mass (CoM) is through an ellipse that encloses 95% of CoP trajectory. The 95% ellipse can be computed under the assumption that the spatial distribution of the CoP points recorded from force platforms is normal...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28248634/health-service-planning-and-sustainable-development-considering-what-where-and-how-care-is-delivered-through-a-pro-environmental-lens
#13
Sharon Desmond
The aim of the present paper was to review the opportunities currently available to health service planners to advance sustainable development in their future-facing roles within health service organisation. Critical challenges and enablers to facilitate health services planners in adopting a pro-environmental lens are discussed.What is known about the topic? Despite its harmful effect on the environment, health has been slower than other industries to embrace the sustainable development agenda. The attitudes and knowledge base of health service planners with regard to environmental sustainability has not been widely studied...
March 2, 2017: Australian Health Review: a Publication of the Australian Hospital Association
https://www.readbyqxmd.com/read/28227631/testing-the-assumption-of-normality-in-body-sway-area-calculations-during-unipedal-stance-tests-with-an-inertial-sensor
#14
Kyoung Jae Kim, Jennifer Lucarevic, Christopher Bennett, Ignacio Gaunaurd, Robert Gailey, Vibhor Agrawal, Kyoung Jae Kim, Jennifer Lucarevic, Christopher Bennett, Ignacio Gaunaurd, Robert Gailey, Vibhor Agrawal, Christopher Bennett, Vibhor Agrawal, Jennifer Lucarevic, Kyoung Jae Kim, Ignacio Gaunaurd, Robert Gailey
The quantification of postural sway during the unipedal stance test is one of the essentials of posturography. A shift of center of pressure (CoP) is an indirect measure of postural sway and also a measure of a person's ability to maintain balance. A widely used method in laboratory settings to calculate the sway of body center of mass (CoM) is through an ellipse that encloses 95% of CoP trajectory. The 95% ellipse can be computed under the assumption that the spatial distribution of the CoP points recorded from force platforms is normal...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28208707/gaitkeeper-a-system-for-measuring-canine-gait
#15
Cassim Ladha, Jack O'Sullivan, Zoe Belshaw, Lucy Asher
It is understood gait has the potential to be used as a window into neurodegenerative disorders, identify markers of subclinical pathology, inform diagnostic algorithms of disease progression and measure the efficacy of interventions. Dogs' gaits are frequently assessed in a veterinary setting to detect signs of lameness. Despite this, a reliable, affordable and objective method to assess lameness in dogs is lacking. Most described canine lameness assessments are subjective, unvalidated and at high risk of bias...
February 8, 2017: Sensors
https://www.readbyqxmd.com/read/28187890/evaluation-of-a-smartphone-based-assessment-system-in-subjects-with-chronic-ankle-instability
#16
Ya-Lan Chiu, Yi-Ju Tsai, Chueh-Ho Lin, You-Ruei Hou, Wen-Hsu Sung
BACKGROUND: Ankle sprain is the most common sports-related injury, and approximately 80% of patients studied suffered recurrent sprains. These repeated ankle injuries could cause chronic ankle instability, a decrease in sports performance, and a decrease in postural control ability. At the present time, smartphones have become very popular and powerful devices, and smartphone applications (apps) that have been shown to have good validity have been designed to measure human body motion...
February 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28166936/cerebellar-disease-of-ruminants
#17
REVIEW
Philippa Gibbons
Cerebellar disease can be congenital or acquired. Clinical signs of cerebellar disease include hypermetric gait in all limbs, normal to increased muscle tone, wide-based stance, swaying, intention tremor, and convulsions. Vestibular signs may be observed. Differential diagnoses for etiology include congenital (hypoplasia, abiotrophy, and lysosomal storage diseases), viral, bacterial, and toxic plants. Animals may present aborted as fetuses or stillborn, be affected at birth, develop disease at a few months old, or acquire the disease later in life...
March 2017: Veterinary Clinics of North America. Food Animal Practice
https://www.readbyqxmd.com/read/28110627/pragmatic-nihilism-how-a-theory-of-nothing-can-help-health-psychology-progress
#18
Gjalt-Jorn Ygram Peters, Rik Crutzen
Health psychology developed a plethora of theories to explain and change a wide variety of behaviours. Several attempts have been undertaken to build integrative theories, some even striving for a Theory of Everything. We argue against these efforts, arguing that instead a 'pragmatic nihilism' perspective may be more fruitful to understand and change health behaviours. The first tenet of pragmatic nihilism is that psychological variables are usefully considered as metaphors rather than referring to entities that exist in the mind...
June 2017: Health Psychology Review
https://www.readbyqxmd.com/read/28054743/hypoglycemia-evaluation-and-reporting-in-diabetes-importance-for-the-development-of-new-therapies
#19
David C Klonoff, G Alexander Fleming, Douglas B Muchmore, Brian M Frier
Hypoglycemia complicating diabetes therapy is well recognized to be an ever-present threat to patients, their families, providers, payers, and regulators. Despite this being widely acknowledged, the regulatory stance on hypoglycemia as an endpoint in clinical trials to support new product registration has not evolved in any meaningful way since the publication of a position paper by an American Diabetes Association (ADA) Workgroup in 2005. As the impact of hypoglycemia on persons affected by diabetes is of major importance when assessing new treatments, the historical position of regulatory agencies on hypoglycemia is reviewed with respect to product approvals...
January 5, 2017: Diabetes/metabolism Research and Reviews
https://www.readbyqxmd.com/read/28017295/older-adults-show-higher-increases-in-lower-limb-muscle-activity-during-whole-body-vibration-exercise
#20
Karin Lienhard, Jordyn Vienneau, Sandro Nigg, Bernd Friesenbichler, Benno M Nigg
The purpose of this study was to compare lower limb muscle activity during whole-body vibration (WBV) exercise between a young and an older study population. Thirty young (25.9±4.3yrs) and thirty older (64.2±5.3yrs) individuals stood on a side-alternating WBV platform while surface electromyography (sEMG) was measured for the tibialis anterior (TA), gastrocnemius medialis (GM), soleus (SOL), vastus lateralis (VL), vastus medialis (VM), and biceps femoris (BF). The WBV protocol included nine vibration settings consisting of three frequencies (6, 11, 16Hz) x three amplitudes (0...
December 14, 2016: Journal of Biomechanics
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