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https://www.readbyqxmd.com/read/28078910/gain-of-chromosome-1q-portends-worse-prognosis-in-multiple-myeloma-despite-novel-agent-based-induction-regimens-and-autologous-transplantation
#1
Gunjan L Shah, Heather Landau, Dory Londono, Sean M Devlin, Satyajit Kosuri, Alexander M Lesokhin, Nikoletta Lendvai, Hani Hassoun, David J Chung, Guenther Koehne, Suresh C Jhanwar, Ola Landgren, Ross Levine, Sergio A Giralt
We aimed to identify whether the use of autologous hematopoietic cell transplantation (HCT) impacts outcomes for multiple myeloma patients with gains of chromosome 1q (+1q). We retrospectively identified 95 patients, 21% having +1q. For patients with +1q, the overall response rate to induction was 85%, with 40% having ≥ VGPR and 20% achieving a CR, similar to non +1q patients (p = .64). The median PFS from diagnosis with +1q was 2.1 years (95% CI: 1.2-not reached (NR)) vs 4.3 years (95% CI: 3...
January 12, 2017: Leukemia & Lymphoma
https://www.readbyqxmd.com/read/28074199/topological-phase-transformations-and-intrinsic-size-effects-in-ferroelectric-nanoparticles
#2
John Mangeri, Yomery Espinal, Andrea Jokisaari, S Pamir Alpay, Serge Nakhmanson, Olle Heinonen
Composite materials comprised of ferroelectric nanoparticles in a dielectric matrix are being actively investigated for a variety of functional properties attractive for a wide range of novel electronic and energy harvesting devices. However, the dependence of these functionalities on shapes, sizes, orientation and mutual arrangement of ferroelectric particles is currently not fully understood. In this study, we utilize a time-dependent Ginzburg-Landau approach combined with coupled-physics finite-element-method based simulations to elucidate the behavior of polarization in isolated spherical PbTiO3 or BaTiO3 nanoparticles embedded in a dielectric medium, including air...
January 11, 2017: Nanoscale
https://www.readbyqxmd.com/read/28066544/controlling-deposition-of-nanoparticles-by-tuning-surface-charge-of-sio2-by-surface-modifications
#3
Johnas Eklöf, Tina Gschneidtner, Samuel Lara-Avila, Kim Nygård, Kasper Moth-Poulsen
The self-assembly of nanoparticles on substrates is relevant for a variety of applications such as plasmonics, sensing devices and nanometer-sized electronics. We investigate the deposition of 60 nm spherical Au nanoparticles onto silicon dioxide (SiO2) substrates by changing the chemical treatment of the substrate and by that altering the surface charge. The deposition is characterized by scanning electron microscopy (SEM). Kelvin probe force microscopy (KPFM) was used to characterize the surface workfunction...
November 13, 2016: RSC Advances
https://www.readbyqxmd.com/read/28064197/cohort-profile-the-western-australian-pregnancy-cohort-raine-study-generation-2
#4
Leon Straker, Jenny Mountain, Angela Jacques, Scott White, Anne Smith, Louis Landau, Fiona Stanley, John Newnham, Craig Pennell, Peter Eastwood
No abstract text is available yet for this article.
January 7, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/28062605/an-interview-with-robert-califf
#5
Misia Landau
No abstract text is available yet for this article.
January 2017: Clinical Chemistry
https://www.readbyqxmd.com/read/28059526/strain-induced-landau-levels-in-arbitrary-dimensions-with-an-exact-spectrum
#6
Stephan Rachel, Ilja Göthel, Daniel P Arovas, Matthias Vojta
Certain nonuniform strain applied to graphene flakes has been shown to induce pseudo-Landau levels in the single-particle spectrum, which can be rationalized in terms of a pseudomagnetic field for electrons near the Dirac points. However, this Landau level structure is, in general, approximate and restricted to low energies. Here, we introduce a family of strained bipartite tight-binding models in arbitrary spatial dimension d and analytically prove that their entire spectrum consists of perfectly degenerate pseudo-Landau levels...
December 23, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/28054209/long-term-outcome-of-expanded-newborn-screening-at-boston-children-s-hospital-benefits-and-challenges-in-defining-true-disease
#7
Yuval E Landau, Susan E Waisbren, Lawrence M A Chan, Harvey L Levy
INTRODUCTION: There is no universal consensus of the disorders included in newborn screening programs. Few studies so far, mostly short-term, have compared the outcome of disorders detected by expanded newborn screening (ENBS) to the outcome of the same disorders detected clinically. METHODS: We compared the clinical and neurodevelopmental outcomes in patients with metabolic disorders detected by ENBS, including biotinidase testing, with those detected clinically and followed at the Metabolism Clinic at Boston Children's Hospital...
January 4, 2017: Journal of Inherited Metabolic Disease
https://www.readbyqxmd.com/read/28045270/effect-of-salt-concentration-on-the-motion-of-particles-near-the-substrate-in-drying-sessile-colloidal-droplets
#8
Guozhi Xu, Wei Hong, Weixiang Sun, Tao Wang, Zhen Tong
The motions of the particles on the substrate of a drying sessile colloidal droplet of water were measured using multiparticle tracking. Droplets with different concentrations (0-250 mM) of sodium chloride (NaCl) were compared. Several statistical quantities were proposed to characterize the heterogeneous behaviors of the particles and distinguish the effects of the flow field and the substrate interaction. For the salt-free droplet, most of the particles were nonadsorbed and mobile without friction. With the presence of salt, the fraction of the adsorbed particles increases with increasing evaporation time and the initial salt concentration, which was explained by Derjaguin-Landau-Verwey-Overbeek interaction...
January 12, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28035088/nematic-films-at-chemically-structured-surfaces
#9
N M Silvestre, M M Telo da Gama, M Tasinkevych
We investigate theoretically the morphology of a thin nematic film adsorbed at flat substrate patterned by stripes with alternating aligning properties, normal and tangential respectively. We construct a simple 'exactly-solvable' effective interfacial model where the liquid crystal distortions are accounted for via an effective interface potential. We find that chemically patterned substrates can strongly deform the nematic-air interface. The amplitude of this substrate-induced undulations increases with decreasing average film thickness and with increasing surface pattern pitch...
February 22, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28031146/visual-perspective-during-remembering-erp-evidence-of-familiarity-based-source-monitoring
#10
P Andrew Leynes, Ben Askin, Joshua D Landau
Autobiographical recollections are accompanied by visual perspectives that can be either a view through the person's own eyes (first-person) or a view that integrates visual characteristics of the rememberer into the reconstructed scene (third-person). Some have argued that a third-person perspective serves as a coping mechanism allowing the person to distance themselves from details of painful memories. The study reported here created first- and third-person memories in a novel experimental paradigm. Later, participants discriminated between these perspectives on a source memory test while event-related potentials (ERPs) were recorded...
December 10, 2016: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28029786/the-wang-landau-reaction-ensemble-method-simulation-of-weak-polyelectrolytes-and-general-acid-base-reactions
#11
Jonas Landsgesell, Christian Holm, Jens Smiatek
We present a novel method for the study of weak polyelectrolytes and general acid-base reactions in molecular dynamics and Monte Carlo simulations. The approach combines the advantages of the reaction ensemble and the Wang-Landau sampling method. Deprotonation and protonation reactions are simulated explicitly with the help of the reaction ensemble method while the accurate sampling of the corresponding phase space is achieved by the Wang-Landau approach. The combination of both techniques provides a sufficient statistical accuracy such that meaningful estimates for the density of states and the partition sum can be obtained...
December 28, 2016: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/28009213/geometric-resonance-of-composite-fermions-near-bilayer-quantum-hall-states
#12
M A Mueed, D Kamburov, L N Pfeiffer, K W West, K W Baldwin, M Shayegan
Via the application of a parallel magnetic field, we induce a single-layer to bilayer transition in two-dimensional electron systems confined to wide GaAs quantum wells and study the geometric resonance of composite fermions (CFs) with a periodic density modulation in our samples. The measurements reveal that CFs exist close to bilayer quantum Hall states, formed at Landau level filling factors ν=1 and 1/2. Near ν=1, the geometric resonance features are consistent with half the total electron density in the bilayer system, implying that CFs prefer to stay in separate layers and exhibit a two-component behavior...
December 9, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/28008882/strained-graphene-hall-bar
#13
S P Milovanović, F M Peeters
The effects of strain, induced by a Gaussian bump, on the magnetic field dependent transport properties of a graphene Hall bar are investigated. The numerical simulations are performed using both classical and quantum mechanical transport theory and we found that both approaches exhibit similar characteristic features. The effects of the Gaussian bump are manifested by a decrease of the bend resistance, R B, around zero-magnetic field and the occurrence of side-peaks in R B. These features are explained as a consequence of bump-assisted scattering of electrons towards different terminals of the Hall bar...
February 22, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28006793/a-revision-of-the-neogene-conidae-and-conorbidae-gastropoda-of-the-paratethys-sea
#14
Mathias Harzhauser, Bernard Landau
The Miocene Conidae and Conorbidae of the central- and south-eastern European Paratethys Sea are revised. In total, 74 species are described of which 10 are new species and 5 are documented for the first time from Paratethyan localities. Species descriptions and delimitations are partly based on morphometric data. In addition, colour patterns are described for the first time for the majority of species. In respect to the ongoing discussion on the supraspecific treatment of extant Conidae, we strongly focus on generic allocations and provide a key for the genera as understood herein...
December 22, 2016: Zootaxa
https://www.readbyqxmd.com/read/28005378/direct-probing-of-the-electronic-structures-of-single-layer-and-bilayer-graphene-with-a-hexagonal-boron-nitride-tunneling-barrier
#15
Suyong Jung, Nojoon Myoung, Jaesung Park, Tae Young Jeong, Hakseong Kim, Kenji Watanabe, Takashi Taniguchi, Dong Han Ha, Chanyong Hwang, Hee Chul Park
The chemical and mechanical stability of hexagonal boron nitride (h-BN) thin films and their compatibility with other free-standing two-dimensional (2D) crystals to form van der Waals heterostructures make the h-BN-2D tunnel junction an intriguing experimental platform not only for the engineering of specific device functionalities but also for the promotion of quantum measurement capabilities. Here, we exploit the h-BN-graphene tunnel junction to directly probe the electronic structures of single-layer and bilayer graphene in the presence and the absence of external magnetic fields with unprecedented high signal-to-noise ratios...
December 27, 2016: Nano Letters
https://www.readbyqxmd.com/read/28000663/robust-fractional-quantum-hall-effect-in-the-n-2-landau-level-in-bilayer-graphene
#16
Georgi Diankov, Chi-Te Liang, François Amet, Patrick Gallagher, Menyoung Lee, Andrew J Bestwick, Kevin Tharratt, William Coniglio, Jan Jaroszynski, Kenji Watanabe, Takashi Taniguchi, David Goldhaber-Gordon
The fractional quantum Hall effect is a canonical example of electron-electron interactions producing new ground states in many-body systems. Most fractional quantum Hall studies have focussed on the lowest Landau level, whose fractional states are successfully explained by the composite fermion model. In the widely studied GaAs-based system, the composite fermion picture is thought to become unstable for the N≥2 Landau level, where competing many-body phases have been observed. Here we report magneto-resistance measurements of fractional quantum Hall states in the N=2 Landau level (filling factors 4<|ν|<8) in bilayer graphene...
December 21, 2016: Nature Communications
https://www.readbyqxmd.com/read/27997372/magnetization-and-ferromagnetic-resonance-in-fe-gd-multilayer-experiment-and-modelling
#17
Alexey Borisovich Drovosekov, Natalia Kreines, Arseny Savitsky, Evgeniy Kravtsov, Marina Ryabukhina, Vyacheslav Proglyado, Vladimir Ustinov
Static and dynamic magnetic properties of a [Fe(35Å)/Gd(50Å)]₁₂ superlattice are investigated experimentally in temperature range 5-295 K using SQUID magnetometery and ferromagnetic resonance (FMR) technique at frequencies 7-38 GHz. The obtained magnetization curves and FMR spectra are analysed theoretically using numerical simulation on the basis of the effective field model. At every given temperature, both static and resonance experimental data can be good approximated within the proposed model. However, a considerable temperature dependence of the effective field parameter in gadolinium layers has to be taken into account to achieve reasonable agreement with the experimental data in the whole studied temperature range...
December 20, 2016: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/27995075/cardiac-failure-in-very-long-chain-acyl-coa-dehydrogenase-deficiency-requiring-extracorporeal-membrane-oxygenation-ecmo-treatment-a-case-report-and-review-of-the-literature
#18
Sharon Katz, Yuval Landau, Ben Pode-Shakked, Itai M Pessach, Marina Rubinshtein, Yair Anikster, Yishay Salem, Gideon Paret
Fatty acid oxidation (FAO) defects often present with multi-system involvement, including several life-threatening cardiac manifestations, such as cardiomyopathy, pericardial effusion and arrhythmias. We report herein a fatal case of cardiac dysfunction and rapid-onset tamponade following an acute illness in a neonate with molecularly proven very long chain acyl-CoA dehydrogenase (VLCAD) deficiency (harboring the known del799_802 mutation), requiring 15 days of extracorporeal membrane oxygenation (ECMO) treatment...
March 2017: Molecular Genetics and Metabolism Reports
https://www.readbyqxmd.com/read/27994226/a-self-consistent-spin-diffusion-model-for-micromagnetics
#19
Claas Abert, Michele Ruggeri, Florian Bruckner, Christoph Vogler, Aurelien Manchon, Dirk Praetorius, Dieter Suess
We propose a three-dimensional micromagnetic model that dynamically solves the Landau-Lifshitz-Gilbert equation coupled to the full spin-diffusion equation. In contrast to previous methods, we solve for the magnetization dynamics and the electric potential in a self-consistent fashion. This treatment allows for an accurate description of magnetization dependent resistance changes. Moreover, the presented algorithm describes both spin accumulation due to smooth magnetization transitions and due to material interfaces as in multilayer structures...
December 2016: Scientific Reports
https://www.readbyqxmd.com/read/27987667/effect-of-preconditioning-cobalt-and-nickel-based-dental-alloys-with-bacillus-sp-extract-on-their-surface-physicochemical-properties-and-theoretical-prediction-of-candida-albicans-adhesion
#20
Mounyr Balouiri, Samira Bouhdid, Moulay Sadiki, Wessal Ouedrhiri, Hassan Barkai, Omar El Farricha, Saad Koraichi Ibnsouda, El Houssaine Harki
Biofilm formation on dental biomaterials is implicated in various oral health problems. Thus the challenge is to prevent the formation of this consortium of microorganisms using a safe approach such as antimicrobial and anti-adhesive natural products. Indeed, in the present study, the effects of an antifungal extract of Bacillus sp., isolated from plant rhizosphere, on the surface physicochemical properties of cobalt and nickel based dental alloys were studied using the contact angle measurements. Furthermore, in order to predict the adhesion of Candida albicans to the treated and untreated dental alloys, the total free energy of adhesion was calculated based on the extended Derjaguin-Landau-Verwey-Overbeek approach...
February 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
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