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meningococcal review

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https://www.readbyqxmd.com/read/29754263/genes-and-their-single-nucleotide-polymorphism-involved-in-innate-immune-response-in-central-nervous-system-in-bacterial-meningitis-review-of-literature-data
#1
REVIEW
Ewelina Gowin, Danuta Januszkiewicz-Lewandowska
BACKGROUND: There are many studies analysing the effect of SNPs in genes coding proteins which are involved in innate immune response on susceptibility to invasive bacterial disease. Many of them gave inconclusive results. Regarding the complexity of immune response and cooperation between particular elements, number of SNPs may have a cumulative effect on the susceptibility to bacterial meningitis. FINDINGS: In most studies cooccurrence of several SNPs was not analysed...
May 12, 2018: Inflammation Research: Official Journal of the European Histamine Research Society ... [et Al.]
https://www.readbyqxmd.com/read/29751133/the-threat-of-meningococcal-disease-during-the-hajj-and-umrah-mass-gatherings-a-comprehensive-review
#2
REVIEW
Saber Yezli
The Hajj and Umrah mass gatherings represent many of the risk factors for meningococcal disease and have historically been associated with both local and international outbreaks of the disease. The implementation of strict preventative measures including mandatory meningococcal vaccination with the quadrivalent (A,C,Y,W) vaccine has prevented pilgrimage-associated meningococcal outbreaks and significantly reduced the incidence of the disease at these events. However, meningococcal disease remains an important public health threat at the Hajj and Umrah due in part to the evolving nature of the disease, characterized with diverse and varying geographic trends, fluctuations in incidence and shifts in serogroups and genotypes...
May 8, 2018: Travel Medicine and Infectious Disease
https://www.readbyqxmd.com/read/29717697/adverse-events-following-immunisation-with-a-meningococcal-serogroup-b-vaccine-report-from-post-marketing-surveillance-germany-2013-to-2016
#3
Dirk Mentzer, Doris Oberle, Brigitte Keller-Stanislawski
Background and aimIn January 2013, a novel vaccine against Neisseria meningitidis serogroup B, the multicomponent meningococcal serogroup B vaccine (4CMenB), was approved by the European Medicines Agency. We aimed to evaluate the safety profile of this vaccine. Methods: All adverse events following immunisation (AEFI) reported from Germany since the vaccine's launch in Germany in November 2013 through December 2016 were reviewed and analysed. Results: Through December 2016, a total of 664 individual case safety reports (ICSR) notifying 1,960 AEFI were received...
April 2018: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/29716545/management-and-control-of-communicable-diseases-in-schools-and-other-child-care-settings-systematic-review-on-the-incubation-period-and-period-of-infectiousness
#4
Ida Czumbel, Chantal Quinten, Pierluigi Lopalco, Jan C Semenza
BACKGROUND: Information on the incubation period and period of infectiousness or shedding of infectious pathogens is critical for management and control of communicable diseases in schools and other childcare settings. METHODS: We performed a systematic literature review (Pubmed and Embase) to identify and critically appraise all relevant published articles using incubation, infectiousness or shedding, and exclusion period as parameters for the search. No language, time, geographical or study design restrictions were applied...
May 2, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29671067/vaccinations-in-pediatric-kidney-transplant-recipients
#5
REVIEW
Thomas G Fox, Corina Nailescu
Pediatric kidney transplant (KT) candidates should be fully immunized according to routine childhood schedules using age-appropriate guidelines. Unfortunately, vaccination rates in KT candidates remain suboptimal. With the exception of influenza vaccine, vaccination after transplantation should be delayed 3-6 months to maximize immunogenicity. While most vaccinations in the KT recipient are administered by primary care physicians, there are specific schedule alterations in the cases of influenza, hepatitis B, pneumococcal, and meningococcal vaccinations; consequently, these vaccines are usually administered by transplant physicians...
April 18, 2018: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/29622828/uncommon-mixed-outbreak-of-pneumococcal-and-meningococcal-meningitis-in-jirapa-district-upper-west-region-ghana-2016
#6
Nuoh R Domo, Culbert Nuolabong, Kofi M Nyarko, Ernest Kenu, Phoebe Balagumyetime, Godfrey Konnyebal, Charles L Noora, Kofi D Ameme, Fred Wurapa, Edwin Afari
Objective: The Jirapa District in Ghana falls within the African meningitis belt where over 500 million people are at risk of epidemic meningitis. The district suffered an outbreak of Neisseria meningitides, W (NMW) in 2012 and a mixed outbreak of Streptococcus pneumonia and NMW in early 2016. We investigated the outbreak to identify the source, causative agents, and magnitude and assess health facility preparedness and propose control measures. Design and Setting: We conducted a descriptive study in all sub-districts of Jirapa, between 28th February to 10th April 2016...
December 2017: Ghana Medical Journal
https://www.readbyqxmd.com/read/29606119/invasive-meningococcal-disease-due-to-a-non-capsulated-neisseria-meningitidis-strain-in-a-patient-with-igg4-related-disease
#7
Shun Kurose, Kyoko Onozawa, Hiroshi Yoshikawa, Kenichiro Yaita, Hideyuki Takahashi, Nobuyuki Shimono, Yoji Nagasaki
BACKGROUND: Invasive Meningococcal Disease (IMD) is a rare and critical disease in Japan. Most of these cases are caused by capsulated Neisseria meningitidis strains. Non-capsulated (non-typable) strains are considered relatively low-pathogenic and can colonize in the nasopharynx of healthy children and young adults. As far as could be ascertained, only twelve IMD cases due to non-capsulated strains have been reported in the literature. No clear risk factors could be identified in a literature review (unknown or immunocompetent, seven cases; C6 deficiency, three cases)...
April 2, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29565712/impact-of-meningococcal-vaccination-on-carriage-and-disease-transmission-a-review-of-the-literature
#8
Paul Balmer, Cynthia Burman, Lidia Serra, Laura J York
Colonization of the human nasopharyngeal tract by the bacterium Neisseria meningitidis is usually asymptomatic, but life-threatening meningococcal disease with a clinical presentation of meningitis, septicemia, or more rarely, gastrointestinal symptoms, can develop. Invasive meningococcal disease (IMD) can be fatal within 24 hours, but IMD is vaccine-preventable. Vaccines used to protect against IMD caused by 5 of the 6 most common serogroups (A, B, C, W, and Y) may also influence carriage prevalence in vaccinated individuals...
March 22, 2018: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29552735/fatigue-following-paediatric-acquired-brain-injury-and-its-impact-on-functional-outcomes-a-systematic-review
#9
Jake Wilkinson, Nohely Lee Marmol, Celia Godfrey, Harriet Wills, Quirine van Eijndhoven, Edith Nardu Botchway, Nikita Sood, Vicki Anderson, Cathy Catroppa
Fatigue is a commonly reported sequela following an acquired brain injury (ABI), and can have a negative impact on many areas of a child's life. However, there is minimal research that focuses on fatigue specifically, and so factors such as its occurrence, duration, and impact on functioning remain uncertain. This systematic review aims to provide a comprehensive summary of the research to date, bringing together a number of studies with a focus on paediatric ABI and fatigue. Terms were searched in relevant databases (PsycInfo, Medline, CINAHL), and articles were included or excluded based on specified criteria...
March 19, 2018: Neuropsychology Review
https://www.readbyqxmd.com/read/29550909/a-review-of-meningococcal-disease-and-vaccination-recommendations-for-travelers
#10
REVIEW
Lidia C Serra, Laura J York, Amgad Gamil, Paul Balmer, Chris Webber
International travel has been steadily increasing since the middle of the twentieth century, including travel to regions with high levels of endemic meningococcal disease and areas with sporadic or sustained meningococcal outbreaks. Although invasive meningococcal disease (IMD) is relatively rare in travelers since the advent of quadrivalent meningococcal vaccines, it remains a serious concern because of its rapid progression, poor prognosis and outcomes, associated treatment delays, and the potential to precipitate outbreaks...
March 17, 2018: Infectious Diseases and Therapy
https://www.readbyqxmd.com/read/29550195/post-licensure-safety-surveillance-study-of-routine-use-of-quadrivalent-meningococcal-diphtheria-toxoid-conjugate-vaccine-menacwy-d-in-infants-and-children
#11
J Hansen, L Zhang, A Eaton, R Baxter, C A Robertson, M D Decker, D P Greenberg, E Bassily, N P Klein
BACKGROUND: Menactra® vaccine (MenACWY-D) was licensed in the United States in 2005 for persons 11-55 years of age, in 2007 for children 2-10 years of age, and in 2011 for infants/toddlers 9-23 months of age. We conducted two studies at Kaiser Permanente Northern California (KPNC), an integrated health care organization, to assess the safety of MenACWY-D in 2-10-year-olds and 9-23-month-olds receiving the vaccine during routine clinical care. METHODS: We conducted observational, retrospective studies of MenACWY-D in 2-10-year-olds (October 2007-October 2010) and in 9-23-month-olds (June 2011-June 2014)...
March 14, 2018: Vaccine
https://www.readbyqxmd.com/read/29543535/vaccination-strategies-for-the-prevention-of-meningococcal-disease
#12
Scott Vuocolo, Paul Balmer, William C Gruber, Kathrin U Jansen, Annaliesa S Anderson, John L Perez, Laura J York
Routine prophylactic vaccination and mass vaccination strategies have been used to control both endemic and epidemic disease caused by Neisseria meningitidis globally. This review discusses real-world examples of these vaccination strategies, their implementation, and outcomes of these efforts, with the overall goal of providing insights on how to achieve optimal control of meningococcal disease through vaccination in varied settings. Tailoring immunization programs to fit the needs of the target population has the potential to optimally reduce disease incidence...
March 15, 2018: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29527576/multidisciplinary-analysis-of-invasive-meningococcal-disease-as-a-framework-for-continuous-quality-and-safety-improvement-in-regional-australia
#13
Kathryn A Taylor, David N Durrheim, Tony Merritt, Peter Massey, John Ferguson, Nick Ryan, Carolyn Hullick
Background: System factors in a regional Australian health district contributed to avoidable care deviations from invasive meningococcal disease (IMD) management guidelines. Traditional root cause analysis (RCA) is not well-suited to IMD, focusing on individual cases rather than system improvements. As IMD requires complex care across healthcare silos, it presents an opportunity to explore and address system-based patient safety issues. Context: Baseline assessment of IMD cases (2005-2006) identified inadequate triage, lack of senior clinician review, inconsistent vital sign recording and laboratory delays as common issues, resulting in antibiotic administration delays and inappropriate or premature discharge...
2018: BMJ Open Quality
https://www.readbyqxmd.com/read/29503815/using-routine-data-sources-to-feed-an-immunization-information-system-for-high-risk-patients-a-pilot-study
#14
Domenico Martinelli, Francesca Fortunato, Stefania Iannazzo, Maria Giovanna Cappelli, Rosa Prato
Background: Vaccine-preventable diseases among high-risk patients are a public health priority in high-income countries. Most national immunization programs have included vaccination recommendations for these population groups but they remain hard-to-reach and coverage data are poorly available. In a pilot study, we developed and tested an automated approach for identifying individuals with underlying medical conditions to feed an immunization information system (IIS). Methods: We reviewed published recommendations on medical conditions that indicate vaccination against influenza, pneumococcal disease, meningococcal disease, hepatitis A, and hepatitis B...
2018: Frontiers in Public Health
https://www.readbyqxmd.com/read/29495347/meningococcal-vaccines-current-status-and-emerging-strategies
#15
REVIEW
Pumtiwitt C McCarthy, Abeer Sharyan, Laleh Sheikhi Moghaddam
Neisseria meningitidis causes most cases of bacterial meningitis. Meningococcal meningitis is a public health burden to both developed and developing countries throughout the world. There are a number of vaccines (polysaccharide-based, glycoconjugate, protein-based and combined conjugate vaccines) that are approved to target five of the six disease-causing serogroups of the pathogen. Immunization strategies have been effective at helping to decrease the global incidence of meningococcal meningitis. Researchers continue to enhance these efforts through discovery of new antigen targets that may lead to a broadly protective vaccine and development of new methods of homogenous vaccine production...
February 25, 2018: Vaccines
https://www.readbyqxmd.com/read/29469759/vaccine-induced-toxic-epidermal-necrolysis-a-case-and-systematic-review
#16
Dev Chahal, Maria Aleshin, Mamina Turegano, Melvin Chiu, Scott Worswick
BACKGROUND: Erythema multiforme (EM), Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are cutaneous hypersensitivityreactions that develop in response to specific triggers such as medications and certain infections. Vaccines, which undergo rigorous safety testing prior to use in humans, are a rare cause of SJS/TEN and little is known about the frequency of such events and corresponding pathogenesis. OBJECTIVE: Herein, we discuss a case of suspected TEN in a 19-year-old woman who received the meningococcal B vaccine (the first report of such an association) and conduct a systematic review of the associated literature...
January 15, 2018: Dermatology Online Journal
https://www.readbyqxmd.com/read/29465257/investigational-drugs-in-development-to-prevent-neuromyelitis-optica-relapses
#17
REVIEW
Friedemann Paul, Olwen Murphy, Santiago Pardo, Michael Levy
In the short time since 2014, three pivotal, worldwide studies in neuromyelitis optica spectrum disorders have been launched: eculizumab, SA237 and inebelizumab, each based on a unique mechanism. Areas covered: In this review, we provide a discussion on the trial data available for each drug, a brief description of the trial design, and our expert opinion on the potential benefits and risks. Expert opinion: Eculizumab, a C5 complement inhibitor, may prove useful in the treatment of intractable cases of NMOSD, but physicians must be aware of the known risk of meningococcal infection...
March 2018: Expert Opinion on Investigational Drugs
https://www.readbyqxmd.com/read/29447987/escmid-study-group-for-infections-in-compromised-hosts-esgich-consensus-document-on-the-safety-of-targeted-and-biological-therapies-an-infectious-diseases-perspective-soluble-immune-effector-molecules-ii-agents-targeting-interleukins-immunoglobulins-and-complement
#18
REVIEW
K L Winthrop, X Mariette, J T Silva, E Benamu, L H Calabrese, A Dumusc, J S Smolen, J M Aguado, M Fernández-Ruiz
BACKGROUND: The present review is part of the ESCMID Study Group for Infections in Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and biological therapies. AIMS: To review, from an Infectious Diseases perspective, the safety profile of agents targeting interleukins, immunoglobulins and complement factors and to suggest preventive recommendations. SOURCES: Computer-based MEDLINE searches with MeSH terms pertaining to each agent or therapeutic family...
February 12, 2018: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/29426026/lung-health-in-era-of-climate-change-and-dust-storms
#19
REVIEW
Michael D Schweitzer, Andrew S Calzadilla, Oriana Salamo, Arash Sharifi, Naresh Kumar, Gregory Holt, Michael Campos, Mehdi Mirsaeidi
Dust storms are strong winds which lead to particle exposure over extensive areas. These storms influence air quality on both a local and global scale which lead to both short and long-term effects. The frequency of dust storms has been on the rise during the last decade. Forecasts suggest that their incidence will increase as a response to the effects of climate change and anthropogenic activities. Elderly people, young children, and individuals with chronic cardiopulmonary diseases are at the greatest risk for health effects of dust storms...
May 2018: Environmental Research
https://www.readbyqxmd.com/read/29393729/challenges-and-opportunities-for-meningococcal-vaccination-in-the-developing-world
#20
Rouba Shaker, Danielle Fayad, Ghassan Dbaibo
Meningococcal disease continues to be a life threatening infection with high morbidity and mortality even in appropriately treated patients. Meningococcal vaccination plays a major role in the control of the disease; however, implementing vaccination remains problematic in the developing world. The objective of this review is to identify the challenges facing the use of meningococcal vaccines in the developing world in order to discuss the opportunities and available solutions to improve immunization in these countries...
February 2, 2018: Human Vaccines & Immunotherapeutics
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