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JOURNAL ARTICLE
Anoop Kumar As, Rima R Sahay, Chandni Radhakrishnan, Shihabudheen P, Sathishkumar Kandath, Deepak Y Patil, Anita M Shete, Shamsudheen M, Gayathri Ramakrishnan, Anitha Puduvail Moorkoth, Nivedita Gupta, Pragya D Yadav, Sheela Godbole, Lathika Velichapat Ramakrishnan, Shameer Vadekkandiyil, Danish Ekkalayil, Nithasha V, Anukumar Balakrishnan, Niyas K Pullor, Neelakandhan Asokan, Reena Kalathil Joseph, Priyanka R Nair, Sreejayan Meethale Purayil, Thomas Mathew, Rajaram Kizhakkekandiyil, Jayesh Kumar Poovullathil, Kannan Sabarinath Ps, Ullas Pt, Kalpana George, Asma Rahim, Surendra Kumar, Siba S, Sreelekshmy Mohandas, Lekshmi S Rajan, Shamin Punnath Ramachandran, Seethu Ponnu Thampi, Ashadevi, Thekkumkara Surendran Anish, Priya Chandran, Anuja Mohan, Bindu Vadakkayil, Shaji Cheriya Koroth, Nimin Hafeez, Rajasi Ranjini Sasi, Minu Abraham
India experienced its sixth Nipah virus (NiV) outbreak in September 2023 in the Kozhikode district of Kerala state. The NiV is primarily transmitted by spillover events from infected bats followed by human-to-human transmission. The clinical specimens were screened using real-time RT-PCR, and positive specimens were further characterized using next-generation sequencing. We describe here an in-depth clinical presentation and management of NiV-confirmed cases and outbreak containment activities. The current outbreak reported a total of six cases with two deaths, with a case fatality ratio of 33...
March 2024: Journal of Medical Virology
#22
Martina Cuccarelli, Lorenzo Schiavoni, Felice Eugenio Agrò, Giuseppe Pascarella, Fabio Costa, Rita Cataldo, Massimiliano Carassiti, Alessia Mattei
Introduction . Extracorporeal membrane oxygenation (ECMO) support for severe acute respiratory distress syndrome (ARDS) is nowadays widely used with notable results on the overall survival as reported in the ELSO registry near to 55% at 90 days. This is the reason why ECMO teams force the use of this extreme technique to several populations, even though there is still a lack of data about its use on hematological patients. Case Report . A 39-year-old woman without a history of previous diseases, but a new diagnosis of acute myeloblastic leukemia (AML) was admitted to intensive care unit (ICU) for worsening hypoxia and respiratory acidosis, presenting an ARDS with PaO2 /FiO2 < 100 in spontaneous breathing treated with noninvasive ventilation via full-face mask...
2024: Case Reports in Critical Care
#23
JOURNAL ARTICLE
Chunxia Wang, Jianli Zheng, Yilin Zhao, Tiantian Liu, Yucai Zhang
OBJECTIVE: Oxygen and hemodynamic management are important for providing a sufficient adequate oxygen-containing blood to the organs for septic patients. In present study, we aimed to explore the application of sequential respiratory support (SRS) and the association of SRS with the outcome of septic patients who needed continuous renal replacement therapy (CRRT). METHODS: We extracted the medical information of septic patients who received CRRT within 24 h of intensive care unit (ICU) admission from the MIMIC-III v1...
March 30, 2024: Heliyon
#24
Manel Luján, César Cinesi Gómez, Oscar Peñuelas, Carlos Ferrando, Sarah Béatrice Heili-Frades, José Manuel Carratalá Perales, Arantxa Mas, Javier Sayas Catalán, Olga Mediano, Oriol Roca, Javier García Fernández, Antonio González Varela, Gonzalo Sempere Montes, Gemma Rialp Cervera, Gonzalo Hernández, Teresa Millán, Miquel Ferrer Monreal, Carlos Egea Santaolalla
Acute respiratory failure due to COVID-19 pneumonia often requires a comprehensive approach that includes non-pharmacological strategies such as non-invasive support (including positive pressure modes, high flow therapy or awake proning) in addition to oxygen therapy, with the primary goal of avoiding endotracheal intubation. Clinical issues such as determining the optimal time to initiate non-invasive support, choosing the most appropriate modality (based not only on the acute clinical picture but also on comorbidities), establishing criteria for recognition of treatment failure and strategies to follow in this setting (including palliative care), or implementing de-escalation procedures when improvement occurs are of paramount importance in the ongoing management of severe COVID-19 cases...
March 4, 2024: Archivos de Bronconeumología
#25
JOURNAL ARTICLE
Chih Chang Chen, Su Ying Hung
BACKGROUND: The community transmission of COVID-19 has caused the breakdown of the regional emergency medical system (REMS), impacting the rights and care of regional patients with acute and severe conditions. This study proposes a model for the surge capacity of REMS to plan for readiness and preparedness during challenging events that overload capacity. METHODS: The surge capacity of REMS during the COVID-19 pandemic was studied. The data collection included 26 hospitals that received the data...
2024: Emergency Medicine International
#26
REVIEW
Zaid Al-Ghazawi, Amwaj Al-Farajat, Ahmad A Toubasi, Hind B Abu Tawileh, Aya Qteish, Tariq N Aladily, Fatima Alnaimat
Aplastic anemia (AA) is a rare, potentially catastrophic hematopoiesis failure manifested by pancytopenia and bone marrow aplasia. AA occurrence in Systemic Lupus Erythematosus (SLE) patients is extremely rare. The diagnosis may be delayed due to other possible pancytopenia etiologies. Confirmation of peripheral cytopenias diagnosis necessitates a bone marrow aspiration. The management of AA is challenging, and the literature reported using glucocorticoids, danazol, plasmapheresis, cyclophosphamide, intravenous immunoglobulin, and cyclosporine...
March 21, 2024: Rheumatology International
#27
Nickjaree Songsangvorn, Yonghao Xu, Cong Lu, Ori Rotstein, Laurent Brochard, Arthur S Slutsky, Karen E A Burns, Haibo Zhang
PURPOSE: Assessing efficacy of electrical impedance tomography (EIT) in optimizing positive end-expiratory pressure (PEEP) for acute respiratory distress syndrome (ARDS) patients to enhance respiratory system mechanics and prevent ventilator-induced lung injury (VILI), compared to traditional methods. METHODS: We carried out a systematic review and meta-analysis, spanning literature from January 2012 to May 2023, sourced from Scopus, PubMed, MEDLINE (Ovid), Cochrane, and LILACS, evaluated EIT-guided PEEP strategies in ARDS versus conventional methods...
March 21, 2024: Intensive Care Medicine
#28
JOURNAL ARTICLE
Aswin Surjit, Bipi Prasannan, Jobin Abraham, Anuroop Balagopal, Vavullipathy Narayanan Unni
AIMS AND BACKGROUND: Extracorporeal membrane oxygenation (ECMO) is a mode of extracorporeal therapy to support oxygenation of patients with severe cardiac or respiratory failure. Studies have shown that acute kidney injury (AKI) can worsen the outcome in these patients. This study aims to assess the incidence and outcome of AKI in patients on ECMO support. MATERIALS AND METHODS: This retrospective study included 64 patients who underwent ECMO for more than 24 hours...
January 2024: Indian Journal of Critical Care Medicine
#29
Jonathan E Schoen, Brian Carr, Murtuza Ali, Brett Chapman, Alan Marr, Lance Stuke, Patrick Greiffenstein, John P Hunt, Paige Deville, Alison Smith
Background: Pulmonary artery embolus is a rare complication following gunshot wounds that creates a unique and serious challenge for trauma surgeons. While the majority of bullets that embolize through the vascular system end in the peripheral circulation, approximately one-third enter the central venous circulation. Case Report: We present the case of a bullet embolus to the left pulmonary artery following gunshot wounds to the right chest and the abdomen, with the abdominal ballistic traversing the liver before entering the vena cava and embolizing...
2024: Ochsner Journal
#30
Case Report: A case of Kounis syndrome induced by iodine contrast agent during coronary angiography.
Yangliu Sun, Jian Zhang
Kounis Syndrome (KS), a seldom-seen adverse reaction to iodine contrast agents, has an incidence that remains unclear. At present, there are no unified guidelines for managing KS either nationally or internationally. Ioversol, a new triiodinated hypotonic nonionic contrast agent, is commonly used in cardiovascular Computed Tomography (CT) and vascular imaging for diagnostic purposes. Its principal adverse reactions encompass fever, dermatological responses, convulsions, respiratory distress, hypersensitivity reactions including KS, and acute renal injury...
2024: Frontiers in Cardiovascular Medicine
#31
JOURNAL ARTICLE
Andreas Kerschbaumer, Josef S Smolen, Ricardo J O Ferreira, Heidi Bertheussen, Xenofon Baraliakos, Daniel Aletaha, Dennis G McGonagle, Désirée van der Heijde, Iain B McInnes, Bente Appel Esbensen, Kevin L Winthrop, Wolf-Henning Boehncke, Jan W Schoones, Laure Gossec
OBJECTIVES: To obtain an overview of recent evidence on efficacy and safety of pharmacological treatments in psoriatic arthritis (PsA). METHODS: This systematic literature research (SLR) investigated the efficacy and safety of conventional synthetic (cs), biological (b) and targeted synthetic (ts) disease-modifying antirheumatic drugs (DMARDs) in patients with PsA. A systematic database search using Medline, EMBASE, Cochrane CENTRAL was conducted to identify relevant articles published since the previous update in 2019 until 28 December 2022...
March 19, 2024: Annals of the Rheumatic Diseases
#32
JOURNAL ARTICLE
Laure Gossec, Andreas Kerschbaumer, Ricardo J O Ferreira, Daniel Aletaha, Xenofon Baraliakos, Heidi Bertheussen, Wolf-Henning Boehncke, Bente Appel Esbensen, Iain B McInnes, Dennis McGonagle, Kevin L Winthrop, Andra Balanescu, Peter V Balint, Gerd R Burmester, Juan D Cañete, Pascal Claudepierre, Lihi Eder, Merete Lund Hetland, Annamaria Iagnocco, Lars Erik Kristensen, Rik Lories, Rubén Queiro, Daniele Mauro, Helena Marzo-Ortega, Philip J Mease, Peter Nash, Wendy Wagenaar, Laura Savage, Georg Schett, Stephanie J W Shoop-Worrall, Yoshiya Tanaka, Filip E Van den Bosch, Annette van der Helm-van Mil, Alen Zabotti, Désirée van der Heijde, Josef S Smolen
OBJECTIVE: New modes of action and more data on the efficacy and safety of existing drugs in psoriatic arthritis (PsA) required an update of the EULAR 2019 recommendations for the pharmacological treatment of PsA. METHODS: Following EULAR standardised operating procedures, the process included a systematic literature review and a consensus meeting of 36 international experts in April 2023. Levels of evidence and grades of recommendations were determined. RESULTS: The updated recommendations comprise 7 overarching principles and 11 recommendations, and provide a treatment strategy for pharmacological therapies...
March 18, 2024: Annals of the Rheumatic Diseases
#33
REVIEW
Saad Qutab, Sunshine Alonzo, A Agatha Crerar-Gilbert, Brendan Madden
The Coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused unprecedented challenges to healthcare professionals (HCPs) worldwide. HCPs faced an unknown disease causing many complications, including now well-established acute respiratory distress syndrome (ARDS) and pulmonary artery thromboembolic disease, and some not so well known, for instance, tracheobronchomalacia, tracheal tear or dehiscence, granulation tissue formation and pulmonary hypertension...
November 2023: Clinical Medicine: Journal of the Royal College of Physicians of London
#34
JOURNAL ARTICLE
Sarah C Katsandres, Jane Hall, Kyle Danielson, Sana Sakr, Sarah G Dean, David J Carlbom, Mark M Wurfel, Pavan K Bhatraju, Joseph A Hippensteel, Eric P Schmidt, Kaori Oshima, Catherine R Counts, Michael R Sayre, Daniel J Henning, Nicholas J Johnson
BACKGROUND: Acute respiratory distress syndrome (ARDS) is often seen in patients resuscitated from out-of-hospital cardiac arrest (OHCA). We aim to test whether inflammatory or endothelial injury markers are associated with the development of ARDS in patients hospitalized after OHCA. METHODS: We conducted a prospective, cohort, pilot study at an urban academic medical center in 2019 that included a convenience sample of adults with non-traumatic OHCA. Blood and pulmonary edema fluid (PEF) were collected within 12 hours of hospital arrival...
March 2024: Resuscitation plus
#35
REVIEW
Richard Greendyk, Rahul Kanade, Madhavi Parekh, Darryl Abrams, Philippe Lemaitre, Cara Agerstrand
BACKGROUND: The use of extracorporeal membrane oxygenation (ECMO) for patients with acute respiratory distress syndrome (ARDS) has increased substantially. With modern trials supporting its efficacy, ECMO has become an important tool in the management of severe ARDS. OBJECTIVES: The objectives of this paper are to discuss ECMO physiology and configurations used for patients with ARDS, review evidence supporting the use of ECMO for ARDS, and discuss aspects of management during ECMO...
March 8, 2024: Medizinische Klinik, Intensivmedizin und Notfallmedizin
#36
JOURNAL ARTICLE
Xinyuan Chen, Michael O Harhay, Guangyu Tong, Fan Li
Assessing heterogeneity in the effects of treatments has become increasingly popular in the field of causal inference and carries important implications for clinical decision-making. While extensive literature exists for studying treatment effect heterogeneity when outcomes are fully observed, there has been limited development in tools for estimating heterogeneous causal effects when patient-centered outcomes are truncated by a terminal event, such as death. Due to mortality occurring during study follow-up, the outcomes of interest are unobservable, undefined, or not fully observed for many participants in which case principal stratification is an appealing framework to draw valid causal conclusions...
March 2024: Annals of Applied Statistics
#37
JOURNAL ARTICLE
Azzaki Abubakar, Fauzi Yusuf, Sarah Firdausa, Desi Maghfirah, Andrie Gunawan, Cut M Yeni, Fitrah Sari
Hepatocellular carcinoma (HCC), a considerable leading cause of cancer-related deaths worldwide, is the most common primary liver cancer with poor prognosis and outcome. Many advances in prevention, screening, and new technologies in diagnostics and therapy have been achieved, but its incidence and mortality remain increasing. Co-infection of another viral disease in HCC patients with pregnancy might exacerbate the condition and double the mortality rate. The aim of this case report was to describe the co-infection of coronavirus disease 2019 (COVID-19) in an HCC patient during pregnancy...
December 2023: Narra J
#38
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
March 1, 2024: Pediatric Critical Care Medicine
#39
JOURNAL ARTICLE
Mehmet Akif Dundar, Tanil Kendirli, Dincer Yildizdas
No abstract text is available yet for this article.
March 1, 2024: Pediatric Critical Care Medicine
#40
JOURNAL ARTICLE
John J Ross, Kevin L Ard
BACKGROUND: Septic arthritis of the spinal facet joints is increasingly recognized in the era of magnetic resonance imaging, but its epidemiology, clinical features, management, and prognosis are ill-defined. METHODS: We review 101 previously published cases and report 16 cases occurring at our institutions between 2006 and 2018. RESULTS: Most patients presented with fever (60%) and back or neck pain (86%). Radiation into the hip, buttock, or limb was present in 34%...
March 2024: Open Forum Infectious Diseases
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