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https://www.readbyqxmd.com/read/28923559/the-independent-effect-of-cancer-on-outcomes-a-potential-limitation-of-surgical-risk-prediction
#1
Ira L Leeds, Joseph K Canner, Jonathan E Efron, Nita Ahuja, Elliott R Haut, Elizabeth C Wick, Fabian M Johnston
BACKGROUND: Cancer patients are often thought to have worse surgical outcomes. There is a growing view that risk models do not adequately predict these outcomes. This study aims to compare the use of common risk models for benign versus malignant gastrointestinal disease. MATERIALS AND METHODS: The National Surgical Quality Improvement Program (NSQIP) 2005-2015 participant use files were queried for patients undergoing elective surgery for benign and malignant diseases with a primary procedure code for major colon, pancreas, or stomach resection...
September 15, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28911065/development-of-an-integrated-electronic-platform-for-patient-self-report-and-management-of-adverse-events-during-cancer-treatment
#2
P Holch, L Warrington, L C A Bamforth, A Keding, L E Ziegler, K Absolom, C Hector, C Harley, O Johnson, G Hall, C Morris, G Velikova
Background: Significant adverse events (AE) during cancer therapy disrupt treatment and escalate to emergency admissions. Approaches to improve the timeliness and accuracy of AE reporting may improve safety and reduce health service costs. Reporting AE via patient reported outcomes (PROs), can improve clinician-patient communication and making data available to clinicians in 'real-time' using electronic PROs (ePROs) could potentially transform clinical practice by providing easily accessible records to guide treatment decisions...
September 1, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/28891854/racial-and-socioeconomic-differences-manifest-in-process-measure-adherence-for-enhanced-recovery-after-surgery-pathway
#3
Ira L Leeds, Yewande Alimi, Deborah R Hobson, Jonathan E Efron, Elizabeth C Wick, Elliott R Haut, Fabian M Johnston
BACKGROUND: Adherence to care processes and surgical outcomes varies by population subgroups for the same procedure. Enhanced recovery after surgery pathways are intended to standardize care, but their effect on process adherence and outcomes for population subgroups is unknown. OBJECTIVE: This study aims to demonstrate the association between recovery pathway implementation, process measures, and short-term surgical outcomes by population subgroup. DESIGN: This study is a pre- and post-quality improvement implementation cohort study...
October 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28879233/low-energy-transmission-electron-diffraction-and-imaging-of-large-area-graphene
#4
Wei Zhao, Bingyu Xia, Li Lin, Xiaoyang Xiao, Peng Liu, Xiaoyang Lin, Hailin Peng, Yuanmin Zhu, Rong Yu, Peng Lei, Jiangtao Wang, Lina Zhang, Yong Xu, Mingwen Zhao, Lianmao Peng, Qunqing Li, Wenhui Duan, Zhongfan Liu, Shoushan Fan, Kaili Jiang
Two-dimensional (2D) materials have attracted interest because of their excellent properties and potential applications. A key step in realizing industrial applications is to synthesize wafer-scale single-crystal samples. Until now, single-crystal samples, such as graphene domains up to the centimeter scale, have been synthesized. However, a new challenge is to efficiently characterize large-area samples. Currently, the crystalline characterization of these samples still relies on selected-area electron diffraction (SAED) or low-energy electron diffraction (LEED), which is more suitable for characterizing very small local regions...
September 2017: Science Advances
https://www.readbyqxmd.com/read/28878950/exercise-dose-and-all-cause-mortality-within-extended-cardiac-rehabilitation-a-cohort-study
#5
Claire Taylor, Costas Tsakirides, James Moxon, James W Moxon, Michael Dudfield, Klaus Witte, Lee Ingle, Sean Carroll
AIMS: To investigate the relationship between exercise participation, exercise 'dose' expressed as metabolic equivalent (MET) hours (h) per week, and prognosis in individuals attending an extended, community-based exercise rehabilitation programme. METHODS: Cohort study of 435 participants undertaking exercise-based cardiac rehabilitation (CR) in Leeds, West Yorkshire, UK between 1994 and 2006, followed up to 1 November 2013. MET intensity of supervised exercise was estimated utilising serial submaximal exercise test results and corresponding exercise prescriptions...
2017: Open Heart
https://www.readbyqxmd.com/read/28864921/invasive-pulmonary-fungal-infections-in-cystic-fibrosis
#6
Carsten Schwarz, Claudia Brandt, Paul Whitaker, Sivagurunathan Sutharsan, Heino Skopnik, Silvia Gartner, Christina Smazny, Jobst F Röhmel
Invasive pulmonary mycosis is after allergic bronchopulmonary aspergillosis (ABPA) a frequent and severe complication of CF lung disease. Among CF caregivers, there is an insecurity when and how to treat infections of the lung parenchyma caused by different fungi in patients with CF. This case series provides a multicenter experience on diagnostic, manifestation, and treatment of non-ABPA cases of pulmonary. Non-ABPA cases of pulmonary mycoses in patients with CF have been collected from the CF Centers in Berlin, Essen, Worms, Frankfurt (Germany), Leeds (UK), and Barcelona (Spain)...
September 1, 2017: Mycopathologia
https://www.readbyqxmd.com/read/28857474/association-between-serum-vitamin-d-levels-and-neuropathic-pain-in-rheumatoid-arthritis-patients-a-cross-sectional-study
#7
Hilal Yesil, Ulas Sungur, Sedef Akdeniz, Gulcan Gurer, Basak Yalcın, Umit Dundar
AIM: Recent literature suggests that neuropathic pain (NP) and vitamin D deficiency can occur concurrently in patients with rheumatoid arthritis (RA). This study aimed to examine the development of NP in patients with RA and the relationship between NP and vitamin D. METHODS: We used the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) questionnaire to evaluate NP in 93 patients with RA. Demographic and clinical data were obtained from patient files and interviews, and patients' serum vitamin D levels were recorded...
August 31, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28856224/an-analysis-of-the-relationship-between-serum-cortisol-and-serum-sodium-in-routine-clinical-patients
#8
Eleanor McLaughlan, Julian H Barth
OBJECTIVES: Adrenal insufficiency is an uncommon cause of hyponatraemia that should not be overlooked due to the severe consequences of an Addisonian crisis. Using the laboratory database of a large teaching hospital, we have explored the relationship between serum sodium and serum cortisol, and have estimated the frequency of hypoadrenalism in severely hyponatraemic patients. DESIGN AND METHODS: Data were gathered over a 23 month period from the Laboratory Information Management System at the Leeds Teaching Hospitals NHS Trust for instances where serum sodium and cortisol had been measured on a single sample...
August 2017: Pract Lab Med
https://www.readbyqxmd.com/read/28843636/management-of-sickle-cell-pain-using-pregabalin-a-pilot-study
#9
Judith M Schlaeger, Robert E Molokie, Yingwei Yao, Marie L Suarez, Julie Golembiewski, Diana J Wilkie, Gina Votta-Velis
Sickle cell disease (SCD) pain may have a neuropathic component. Adjuvant drugs used to treat neuropathic pain have not been studied for the treatment of adults with SCD. To determine the safety and feasibility of using pregabalin for chronic SCD pain. A randomized, controlled, double-blind pilot study. Based on random assignment, participants were treated with pregabalin or placebo control for 3 months with monthly follow-up visits. Participants were recruited from the University of Illinois Hospital and Health Sciences System outpatient SCD clinic...
August 23, 2017: Pain Management Nursing: Official Journal of the American Society of Pain Management Nurses
https://www.readbyqxmd.com/read/28840267/erratum-to-prospective-clinical-and-pharmacological-evaluation-of-the-delcath-system-s-second-generation-gen2-hemofiltration-system-in-patients-undergoing-percutaneous-hepatic-perfusion-with-melphalan
#10
Eleonora M de Leede, Mark C Burgmans, T Susanna Meijer, Christian H Martini, Fred G J Tijl, Jaap Vuyk, Arian R van Erkel, Cornelis J H van der Velde, Ellen Kapiteijn, Alexander L Vahrmeijer
No abstract text is available yet for this article.
August 23, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28836099/cutaneous-manifestations-of-small-vessel-leukocytoclastic-vasculitides-in-childhood
#11
REVIEW
Sebastiano A G Lava, Gregorio P Milani, Emilio F Fossali, Giacomo D Simonetti, Carlo Agostoni, Mario G Bianchetti
In childhood, cutaneous small-vessel vasculitides include Henoch-Schönlein syndrome, a systemic vasculitis, and Finkelstein-Seidlmayer syndrome, a skin-limited vasculitis. Both Henoch-Schönlein and Finkelstein-Seidlmayer syndromes are seen more frequently in white or Asian compared with black children and occur especially in winter and spring with a male-to-female ratio of approximately 2:1. In everyday clinical practice, both conditions are diagnosed on clinical grounds without histological confirmation...
August 24, 2017: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/28832149/decomposition-of-methanol-on-mixed-cuo-cuwo4-surfaces
#12
Matthias A Blatnik, Carl Drechsel, Nataliya Tsud, Svetlozar Surnev, Falko P Netzer
Mixed CuO(2x1)-CuWO4 layers on a Cu(110) surface have been prepared by the on-surface reaction of the CuO(2x1) surface oxide with adsorbed (WO3)3 clusters. The adsorption and decomposition of methanol on these well-defined CuO-CuWO4 surfaces has been followed by high-resolution X-ray photoelectron spectroscopy (XPS), high-resolution electron energy loss spectroscopy (HREELS), and temperature programmed desorption (TPD) to assess the molecular surface species and their concentration, while the state of the surface oxide phases before and after methanol decomposition has been characterized by scanning tunneling microscopy (STM), low energy electron diffraction (LEED) and XPS...
August 23, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28831113/rna-seq-reveals-microrna-expression-signature-and-genetic-polymorphism-associated-with-growth-and-muscle-quality-traits-in-rainbow-trout
#13
Bam Dev Paneru, Rafet Al-Tobasei, Brett Kenney, Timothy D Leeds, Mohamed Salem
The role of microRNA expression and genetic variation in microRNA-binding sites of target genes on growth and muscle quality traits is poorly characterized. We used RNA-Seq approach to investigate their importance on 5 growth and muscle quality traits: whole body weight (WBW), muscle yield, muscle crude-fat content, muscle shear force and whiteness. Phenotypic data were collected from 471 fish, representing 98 families (~5 fish/family) from a growth-selected line. Muscle microRNAs and mRNAs were sequenced from 22 families showing divergent phenotypes...
August 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28830870/good-practice-or-positive-action-using-q-methodology-to-identify-competing-views-on-improving-gender-equality-in-academic-medicine
#14
Louise D Bryant, Paula Burkinshaw, Allan O House, Robert M West, Vicky Ward
OBJECTIVES: The number of women entering medicine has increased significantly, yet women are still under-represented at senior levels in academic medicine. To support the gender equality action plan at one School of Medicine, this study sought to (1) identify the range of viewpoints held by staff on how to address gender inequality and (2) identify attitudinal barriers to change. DESIGN: Q methodology. 50 potential interventions representing good practice or positive action, and addressing cultural, organisational and individual barriers to gender equality, were ranked by participants according to their perception of priority...
August 22, 2017: BMJ Open
https://www.readbyqxmd.com/read/28827933/validation-of-the-malayalam-version-of-leeds-assessment-of-neuropathic-symptoms-and-signs-pain-scale-in-cancer-patients-in-the-regional-cancer-centre-thiruvananthapuram-kerala-india
#15
Shoukkathali Anzar, Cherian Koshy, Kurian Mathew Abraham
OBJECTIVE: The Self-administered Leeds Assessment of Neuropathic Symptoms and Signs (S-LANSS) is a 7-item self-report scale developed to identify pain which is of predominantly neuropathic origin. The aim of this study was to develop a Malayalam version of the LANSS and to test its validity and reliability in chronic pain patients. METHODOLOGY: We enrolled 101 Malayalam-speaking chronic pain patients who visited the Division of Palliative Medicine, Regional Cancer Centre, Thiruvananthapuram, Kerala, India...
July 2017: Indian Journal of Palliative Care
https://www.readbyqxmd.com/read/28820783/epidemiology-of-obesity-in-the-hispanic-adult-population-in-the-united-states
#16
Kimberly Y Z Forrest, Marcy J Leeds, Alexander C Ufelle
Obesity is a major health concern in Hispanic populations. This study evaluated the epidemiology of obesity and associated factors among Hispanics using the data from the 2013-2014 National Health and Nutrition Examination Survey. Among the 1241 participants (20 years of age or older), the prevalence rates were as follows: overweight, 77.1%; obesity, 42.4%; and central obesity, 57.0%. These rates were consistent throughout most age groups. Significantly, more females than males were obese. Higher obesity rates were seen among those with diabetes, high cholesterol, hypertension, heart disease, and arthritis...
October 2017: Family & Community Health
https://www.readbyqxmd.com/read/28819916/early-surgical-intervention-for-acute-ulcerative-colitis-is-associated-with-improved-postoperative-outcomes
#17
Ira L Leeds, Brindusa Truta, Alyssa M Parian, Sophia Y Chen, Jonathan E Efron, Susan L Gearhart, Bashar Safar, Sandy H Fang
BACKGROUND: Timing of surgical intervention for acute ulcerative colitis has not been fully examined during the modern immunotherapy era. Although early surgical intervention is recommended, historical consensus for "early" ranges widely. The purpose of this study was to evaluate outcomes according to timing of urgent surgery for acute ulcerative colitis. METHODS: All non-elective total colectomies in ulcerative colitis patients were identified in the National Inpatient Sample from 2002 to 2014...
August 17, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28800689/evaluation-of-edar-vehicle-emissions-remote-sensing-technology
#18
Karl Ropkins, Timothy H DeFries, Francis Pope, David C Green, Jim Kemper, Sandeep Kishan, Gary W Fuller, Hu Li, Jim Sidebottom, Leigh R Crilley, Louisa Kramer, William J Bloss, J Stewart Hager
Despite much work in recent years, vehicle emissions remain a significant contributor in many areas where air quality standards are under threat. Policy-makers are actively exploring options for next generation vehicle emission control and local fleet management policies, and new monitoring technologies to aid these activities. Therefore, we report here on findings from two separate but complementary blind evaluation studies of one new-to-market real-world monitoring option, HEAT LLC's Emission Detection And Reporting system or EDAR, an above-road open path instrument that uses Differential Absorption LIDAR to provide a highly sensitive and selective measure of passing vehicle emissions...
December 31, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28792839/confidence-and-competence-is-what-makes-the-difference-on-the-frontline
#19
Clare Price-Dowd
In this third blog in the series, Clare Price-Dowd, Senior Programme Lead, NHS Leadership Academy, Leeds, discusses the importance of having both confident and competent nurses delivering care.
August 10, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28792036/probing-the-interplay-between-geometric-and-electronic-structure-in-a-two-dimensional-k-tcnq-charge-transfer-network
#20
P J Blowey, L A Rochford, D A Duncan, D A Warr, T-L Lee, D P Woodruff, G Costantini
Scanning tunnelling microscopy (STM), low energy electron diffraction (LEED), ultraviolet and soft X-ray photoelectron spectroscopy (UPS and SXPS) have been used to characterise the formation of a coadsorption phase of TCNQ and K on Ag(111), while the normal incident X-ray standing waves (NIXSW) technique has been used to obtain quantitative structural information. STM and LEED show that an ordered incommensurate phase is formed in which the K atoms are surrounded by four TCNQ molecules in a 'windmill' motif, characteristic of other metal/TCNQ phases, in which the nominal TCNQ : K stoichiometry is 1 : 1...
August 9, 2017: Faraday Discussions
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