keyword
MENU ▼
Read by QxMD icon Read
search

Leeds

keyword
https://www.readbyqxmd.com/read/28077697/point-counterpoint-what-is-the-optimal-approach-for-detection-of-clostridium-difficile-infection
#1
Ferric C Fang, Christopher R Polage, Mark H Wilcox
In 2010, we published an initial point-counterpoint on laboratory diagnosis of C. difficile infection (CDI). At that time, nucleic acid amplification tests (NAATs) were just becoming commercially available, and the idea of algorithmic approaches to CDI was being explored. Now there are numerous NAATs in the marketplace and based on recent proficiency test surveys, they have become the predominant method used for CDI diagnosis in the United States. At the same time, there is a body of literature that suggests that NAATs lack clinical specificity and thus inflate CDI rates...
January 11, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28073039/effect-of-sleep-problems-on-depressive-disorders-1-year-after-developing-acute-coronary-syndrome-the-k-depacs-study
#2
Jae-Min Kim, Hee-Ju Kang, Kyung-Yeol Bae, Sung-Wan Kim, Il-Seon Shin, Young Joon Hong, Youngkeun Ahn, Myung Ho Jeong, Jin-Sang Yoon
INTRODUCTION: This study investigated the effects of sleep disturbance evaluated within 2 weeks after patients developed acute coronary syndrome (ACS) on depressive disorders at the 1-year follow-up. METHODS: A total of 1152 patients were recruited consecutively within 2 weeks after a confirmed ACS episode, and 828 were followed 1 year later. Sleep disturbances were evaluated at baseline using the Leeds Sleep Evaluation Questionnaire (LSEQ), which subjectively assesses four sleep factors...
January 3, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28056911/prospective-cohort-study-of-procalcitonin-levels-in-children-with-cancer-presenting-with-febrile-neutropenia
#3
Victoria Hemming, Adam D Jakes, Geoff Shenton, Bob Phillips
BACKGROUND: Febrile neutropenia (FNP) causes significant morbidity and mortality in children undergoing treatment for cancer. The development of clinical decision rules to help stratify risks in paediatric FNP patients and the use of inflammatory biomarkers to identify high risk patients is an area of recent research. This study aimed to assess if procalcitonin (PCT) levels could be used to help diagnose or exclude severe infection in children with cancer who present with febrile neutropenia, both as a single measurement and in addition to previously developed clinical decision rules...
January 5, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28048750/su-f-j-26-performance-of-2-5mv-portal-imaging-in-comparison-with-kv-x-ray-and-6mv-and-flattening-filter-free-6mv-portal-imaging
#4
J Duan, Y Yang, A Faught, E Subashi, Q Wu, F Yin
PURPOSE: To assess image quality and imaging dose of 2.5MV electronic portal imaging in comparison to kV imaging and 6MV and Flattening-Filter-Free 6MV (6MVFFF) portal imaging using a DMI imager. METHODS: Quantitative assessment of image quality was performed with Leeds and Las Vegas test phantoms in conjunction with qualitative evaluation of clinical patient images for kV imaging and 2.5MV, 6MV and 6MVFFF portal imaging. High and low contrast resolutions were evaluated and imaging doses were measured using these x-rays...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28043211/comparison-of-heat-induced-damage-at-the-saphenofemoral-junction-after-ablation-with-1-470-nm-laser-or-radiofrequency
#5
Evren Ozcinar, Mehmet Cakici, Oktay Korun, Unsal Han, Ugursay Kiziltepe
BACKGROUND: The aim of this study was to evaluate the heat induced damage at the saphenofemoral junction level according to histopathological changes after radiofrequency or 1,470 nm radial tip laser ablation. PATIENTS AND METHODS: Varicose vein segments of 6-10 mm in diameter were exposed to radiofrequency (Closure Fast catheter, 7 cm heat segment, one cycle, 15 seconds, 10 Watt, 120 °C) or laser ablation (1,470 nm radial tip, continuous wave, vein diameter: 6 cm/8 cm/10 cm-power: 10 Watt-pullback speed: 2...
January 3, 2017: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/28031936/diabesity-management-worldwide
#6
Chinnadorai Rajeswaran
Francesca Lake, Managing Editor, speaks to Chinnadorai Rajeswaran. Dr Rajeswaran is a consultant physician (Diabetes & Endocrinology) at Mid Yorkshire NHS Trust. He gained specialist training in Leeds, in diabetes and endocrinology. He has a special interest in obesity and is involved in research in obesity and diabetes. He also has a number of publications, book chapters and presentations to his credit. He along with other co-authors has published a book on weight loss surgery, titled: "The Ultimate Guide to Weight Loss Surgery...
March 2016: Future Science OA
https://www.readbyqxmd.com/read/28029373/discharge-decision-making-after-complex-surgery-surgeon-behaviors-compared-to-predictive-modeling-to-reduce-surgical-readmissions
#7
Ira L Leeds, Vjollca Sadiraj, James C Cox, Xiaoxue Sherry Gao, Timothy M Pawlik, Kurt E Schnier, John F Sweeney
BACKGROUND: Little is known about how information available at discharge affects decision-making and its effect on readmission. We sought to define the association between information used for discharge and patients' subsequent risk of readmission. METHODS: 2009-2014 patients from a tertiary academic medical center's surgical services were analyzed using a time-to-event model to identify criteria that statistically explained the timing of discharges. The data were subsequently used to develop a time-varying prediction model of unplanned hospital readmissions...
October 20, 2016: American Journal of Surgery
https://www.readbyqxmd.com/read/27993145/pressure-relieving-support-surfaces-a-randomised-evaluation-2-pressure-2-study-protocol-for-a-randomised-controlled-trial
#8
Sarah Brown, Isabelle L Smith, Julia M Brown, Claire Hulme, Elizabeth McGinnis, Nikki Stubbs, E Andrea Nelson, Delia Muir, Claudia Rutherford, Kay Walker, Valerie Henderson, Lyn Wilson, Rachael Gilberts, Howard Collier, Catherine Fernandez, Suzanne Hartley, Moninder Bhogal, Susanne Coleman, Jane E Nixon
BACKGROUND: Pressure ulcers represent a major burden to patients, carers and the healthcare system, affecting approximately 1 in 17 hospital and 1 in 20 community patients. They impact greatly on an individual's functional status and health-related quality of life. The mainstay of pressure ulcer prevention practice is the provision of pressure redistribution support surfaces and patient repositioning. The aim of the PRESSURE 2 study is to compare the two main mattress types utilised within the NHS: high-specification foam and alternating pressure mattresses, in the prevention of pressure ulcers...
December 20, 2016: Trials
https://www.readbyqxmd.com/read/27986742/assessment-of-the-effectiveness-and-safety-of-ethosuximide-in-the-treatment-of-non-diabetic-peripheral-neuropathic-pain-edonot-protocol-of-a-randomised-parallel-controlled-double-blinded-and-multicentre-clinical-trial
#9
Nicolas Kerckhove, Christophe Mallet, Bruno Pereira, Chouki Chenaf, Christian Duale, Claude Dubray, Alain Eschalier
INTRODUCTION: Currently available analgesics are ineffective in 30-50% of patients suffering from neuropathic pain and often induce deleterious side effects. T-type calcium channel blockers (mibefradil, ethosuximide, NNC 55-0396) are of great interest for the development of new symptomatic treatments of neuropathic pain, due to their various effects on pain perception. Interestingly, ethosuximide, which has already been approved for treating epilepsy, is available on the European market for clinical use...
December 16, 2016: BMJ Open
https://www.readbyqxmd.com/read/27981917/an-observational-study-to-assess-if-automated-diabetic-retinopathy-image-assessment-software-can-replace-one-or-more-steps-of-manual-imaging-grading-and-to-determine-their-cost-effectiveness
#10
Adnan Tufail, Venediktos V Kapetanakis, Sebastian Salas-Vega, Catherine Egan, Caroline Rudisill, Christopher G Owen, Aaron Lee, Vern Louw, John Anderson, Gerald Liew, Louis Bolter, Clare Bailey, SriniVas Sadda, Paul Taylor, Alicja R Rudnicka
BACKGROUND: Diabetic retinopathy screening in England involves labour-intensive manual grading of retinal images. Automated retinal image analysis systems (ARIASs) may offer an alternative to manual grading. OBJECTIVES: To determine the screening performance and cost-effectiveness of ARIASs to replace level 1 human graders or pre-screen with ARIASs in the NHS diabetic eye screening programme (DESP). To examine technical issues associated with implementation. DESIGN: Observational retrospective measurement comparison study with a real-time evaluation of technical issues and a decision-analytic model to evaluate cost-effectiveness...
December 2016: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/27974663/pik3ca-mutations-enable-targeting-of-a-breast-tumor-dependency-through-mtor-mediated-mcl-1-translation
#11
Grace R Anderson, Suzanne E Wardell, Merve Cakir, Lorin Crawford, Jim C Leeds, Daniel P Nussbaum, Pallavi S Shankar, Ryan S Soderquist, Elizabeth M Stein, Jennifer P Tingley, Peter S Winter, Elizabeth K Zieser-Misenheimer, Holly M Alley, Alexander Yllanes, Victoria Haney, Kimberly L Blackwell, Shannon J McCall, Donald P McDonnell, Kris C Wood
Therapies that efficiently induce apoptosis are likely to be required for durable clinical responses in patients with solid tumors. Using a pharmacological screening approach, we discovered that combined inhibition of B cell lymphoma-extra large (BCL-XL) and the mammalian target of rapamycin (mTOR)/4E-BP axis results in selective and synergistic induction of apoptosis in cellular and animal models of PIK3CA mutant breast cancers, including triple-negative tumors. Mechanistically, inhibition of mTOR/4E-BP suppresses myeloid cell leukemia-1 (MCL-1) protein translation only in PIK3CA mutant tumors, creating a synthetic dependence on BCL-XL This dual dependence on BCL-XL and MCL-1, but not on BCL-2, appears to be a fundamental property of diverse breast cancer cell lines, xenografts, and patient-derived tumors that is independent of the molecular subtype or PIK3CA mutational status...
December 14, 2016: Science Translational Medicine
https://www.readbyqxmd.com/read/27965829/the-challenge-of-mothers-learning-about-secondhand-smoke-mlass-a-quasi-experimental-mixed-methods-feasibility-study
#12
Rachel Mann, Heather Thomson, Becky Reynolds, Amanda Amos, Kamran Siddiqi
BACKGROUND: Exposure to secondhand smoke (SHS) in the antenatal and postnatal period is associated with a detrimental health impact to the foetus and newborn baby and is recognised as a preventable public health challenge. The aim of the mother's learning about secondhand smoke (MLASS) study was to test the feasibility of delivering and evaluating the effectiveness of a smoke-free homes (SFH) health education intervention in the antenatal and postnatal period to reduce foetal and newborn exposure to SHS...
2016: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/27965825/aminoaciduria-in-the-prediction-of-ifosfamide-induced-tubulopathy-after-childhood-cancer-a-feasibility-study
#13
Jessica E Morgan, Karl McKeever, Kay S Tyerman, Michael Henderson, Susan Picton, Robert S Phillips
BACKGROUND: Ifosfamide, an alkylating agent used widely in the treatment of childhood malignancy, can cause many side effects including a proximal tubulopathy. Studies suggest that aminoaciduria is seen most commonly of all the biochemical abnormalities of ifosfamide-induced tubulopathy. A recent systematic review has found a paucity of data regarding the value of early markers indicating clinically significant tubulopathy. We undertook a pilot study to determine the feasibility of examining whether patients can be risk-stratified on the basis of aminoaciduria for the development of future significant ifosfamide-induced tubulopathy, to allow the evolution of appropriate follow-up strategies...
2016: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/27940628/what-determines-duration-of-palliative-care-before-death-for-patients-with-advanced-disease-a-retrospective-cohort-study-of-community-and-hospital-palliative-care-provision-in-a-large-uk-city
#14
Michael I Bennett, Lucy Ziegler, Matthew Allsop, Sunitha Daniel, Adam Hurlow
OBJECTIVE: For patients with advanced cancer, several randomised controlled trials have shown that access to palliative care at least 6 months before death can improve symptoms, reduce unplanned hospital admissions, minimise aggressive cancer treatments and enable patients to make choices about their end-of-life care, including exercising the choice to die at home. This study determines in a UK population the duration of palliative care before death and explores influencing factors...
December 9, 2016: BMJ Open
https://www.readbyqxmd.com/read/27939112/validity-and-reliability-of-the-spanish-language-version-of-the-self-administered-leeds-assessment-of-neuropathic-symptoms-and-signs-s-lanss-pain-scale
#15
I López-de-Uralde-Villanueva, A Gil-Martínez, P Candelas-Fernández, J de Andrés-Ares, H Beltrán-Alacreu, R La Touche
INTRODUCTION: The self-administered Leeds Assessment of Neuropathic Symptoms and Signs (S-LANSS) scale is a tool designed to identify patients with pain with neuropathic features. OBJECTIVE: To assess the validity and reliability of the Spanish-language version of the S-LANSS scale. METHODS: Our study included a total of 182 patients with chronic pain to assess the convergent and discriminant validity of the S-LANSS; the sample was increased to 321 patients to evaluate construct validity and reliability...
December 8, 2016: Neurología: Publicación Oficial de la Sociedad Española de Neurología
https://www.readbyqxmd.com/read/27920797/genome-wide-association-study-for-identifying-loci-that-affect-fillet-yield-carcass-and-body-weight-traits-in-rainbow-trout-oncorhynchus-mykiss
#16
Dianelys Gonzalez-Pena, Guangtu Gao, Matthew Baranski, Thomas Moen, Beth M Cleveland, P Brett Kenney, Roger L Vallejo, Yniv Palti, Timothy D Leeds
Fillet yield (FY, %) is an economically-important trait in rainbow trout aquaculture that affects production efficiency. Despite that, FY has received little attention in breeding programs because it is difficult to measure on a large number of fish and cannot be directly measured on breeding candidates. The recent development of a high-density SNP array for rainbow trout has provided the needed tool for studying the underlying genetic architecture of this trait. A genome-wide association study (GWAS) was conducted for FY, body weight at 10 (BW10) and 13 (BW13) months post-hatching, head-off carcass weight (CAR), and fillet weight (FW) in a pedigreed rainbow trout population selectively bred for improved growth performance...
2016: Frontiers in Genetics
https://www.readbyqxmd.com/read/27918655/activity-profiles-and-positional-differences-of-handball-players-during-the-world-championships-in-qatar-2015
#17
Marco Cardinale, Rodney Whiteley, Ahmed Abdelrahman Hosny, Nebojsa Popovic
PURPOSE: Handball is an Olympic sport played indoor by 6 court players and one goalkeeper with rolling substitutions. Limited data exist on elite players competing in a World Championship and virtually no information exits on the evolution of time-motion performance over the course of a long tournament. Therefore, the aim of this study was to analyze time motion characteristics of elite male handball players of the last World Championships played in Qatar in 2015. METHODS: 384 Players from 24 national teams were analyzed during 88 matches using a tracking camera system and a bespoke software (Prozone Handball V...
December 5, 2016: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/27916242/the-effect-of-pregabalin-and-methylcobalamin-combination-on-the-chronic-postthoracotomy-pain-syndrome
#18
Serda Kanbur Metin, Burhan Meydan, Serdar Evman, Talha Dogruyol, Volkan Baysungur
BACKGROUND: Chronic postthoracotomy pain (CPTP) consists of different types of pain. Some characteristics of CPTP are the same as those of recognized neuropathic pain syndromes. We aimed to determine the safety and efficacy of pregabalin and methylcobalamin combination (PG-B12) in comparison with diclofenac potassium (DP) in patients with CPTP. METHODS: One hundred consecutive patients with CPTP after posterolateral/lateral thoracotomy were prospectively randomly assigned and evaluated...
December 1, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27902134/-shout-it-from-the-rooftops
#19
(no author information available yet)
Former Nursing Standard Nurse of the Year Stacey Atkinson trained in Leeds at a school of nursing attached to a hospital for people with learning disabilities. She qualified in 1990 and worked in residential care and as a community learning disability nurse for children and adults before moving into education. Married with two children, she is now a senior lecturer at the University of Huddersfield. In 2003 she was awarded an MBE for services to children with learning disabilities.
November 30, 2016: Nursing Standard
https://www.readbyqxmd.com/read/27900299/assessment-of-enthesitis-in-patients-with-psoriatic-arthritis-using-clinical-examination-and-ultrasound
#20
Salome Kristensen, Jeppe Hagstrup Christensen, Erik Berg Schmidt, Jens Lykkegaard Olesen, Martin Berg Johansen, Kristian Bakke Arvesen, Annette Schlemmer
BACKGROUND: Enthesitis is a major feature of psoriatic arthritis. However, clinical assessment of enthesitis is known to lack accuracy and have poor interobserver reliability. OBJECTIVE: To determine effect of training on clinical assessment of enthesitis and to compare ultrasonography with clinical examination for the detection of entheseal abnormalities. METHODS: 20 rheumatologists performed repeated assessment of enthesitis in patients with established psoriatic arthritis before and after a 2-hour training session in standardised enthesitis count according to Leeds Enthesitis Index (LEI) and Spondyloarthritis Research Consortium of Canada Enthesitis Index (SPARCC)...
April 2016: Muscles, Ligaments and Tendons Journal
keyword
keyword
9001
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"