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https://www.readbyqxmd.com/read/25892981/clinical-rationale-for-confirmation-testing-after-treatment-of-helicobacter-pylori-infection-implications-of-rising-antibiotic-resistance
#1
Colin W Howden, William D Chey, Nimish B Vakil
Helicobacter pylori (H pylori) infection is one of the most common chronic bacterial infections worldwide. International guidelines recommend H pylori eradication in several scenarios: patients with peptic ulcer disease, patients who have had endoscopic resection of early gastric cancer, and patients with a gastric mucosa-associated lymphoid tissue lymphoma (MALToma). There is variability among the guidelines for other conditions. Treatment options for H pylori infection include triple, quadruple, and sequential therapy...
July 2014: Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/24732195/the-korean-perspective-of-helicobacter-pylori-infection-lessons-from-the-japanese-government-s-policy-to-prevent-gastric-cancer
#2
REVIEW
Jong-Min Park, Ki Baik Hahm
The guideline of the Korean College of Helicobacter and Upper Gastrointestinal Research group for Helicobacter pylori infection was first produced in 1998, when definite indication for H. pylori eradication is early gastric cancer in addition to the previous indications of peptic ulcer (PUD) including scar lesion and marginal zone B cell lymphoma (MALT type). Though treatment is recommended for the relatives of a patient with gastric cancer, unexplained iron deficiency anemia, and chronic idiopathic thrombocytopenic purpura, a consensus treatment guideline is the treatment of PUD, MALToma, and gastric cancer in Korea...
2014: Digestive Diseases
https://www.readbyqxmd.com/read/24106407/clinical-outcomes-of-radiation-therapy-for-early-stage-gastric-mucosa-associated-lymphoid-tissue-lymphoma
#3
Sang-Won Kim, Do Hoon Lim, Yong Chan Ahn, Won Seog Kim, Seok Jin Kim, Young Hyeh Ko, Kyoung-Mee Kim
AIM: To evaluate the clinical outcomes of radiation therapy (RT) for early-stage gastric mucosa-associated lymphoid tissue lymphoma (MALToma). METHODS: The records of 64 patients treated between 1998 and 2011 were analyzed retrospectively. For Helicobacter pylori (H. pylori)-positive patients (n = 31), chemotherapy or H. pylori eradication therapy was the initial treatment. In patients with failure after H. pylori eradication, RT was performed. For H. pylori-negative patients (n = 33), chemotherapy or RT was the first-line treatment...
September 28, 2013: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/23236238/trends-in-the-eradication-rates-of-helicobacter-pylori-infection-for-eleven-years
#4
Jai Hoon Yoon, Gwang Ho Baik, Kyoung Min Sohn, Dae Yong Kim, Yeon Soo Kim, Ki Tae Suk, Jin Bong Kim, Dong Joon Kim, Jin Bae Kim, Woon Geon Shin, Hak Yang Kim, Il Hyun Baik, Hyun Joo Jang
AIM: To evaluate the trends in the eradication rate of Helicobacter pylori (H. pylori) over the past 11 years in a single center. METHODS: This retrospective study covered the period from January 2000 to December 2010. We evaluated 5746 patients diagnosed with gastric ulcers (GU), duodenal ulcers (DU), GU + DU, or nonpeptic ulcers associated with an H. pylori infection. We treated them annually with the 2 wk standard first-line triple regimen, proton pump inhibitor (PPI) + amoxicilin + clarithromycin (PAC; PPI, clarithromycin 500 mg, and amoxicillin 1 g, all twice a day)...
December 7, 2012: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/22586541/recognition-of-changes-in-microvascular-and-microstructural-patterns-upon-magnifying-endoscopy-predicted-the-presence-of-extranodal-gastric-maltoma
#5
Philip Wai Yan Chiu, Tiffany Cho Lam Wong, Anthony Yuen Bun Teoh, Kai Fai To, Shirley Yuk Wah Liu, Simon Kin Hung Wong, Francis Ka Leung Chan, Enders Kwok Wai Ng
BACKGROUND AND OBJECTIVES: Gastric MALToma is difficult to recognize upon endoscopy. The aim of this study is to evaluate the application of microstructural and microvascular patterns in recognizing gastric MALToma on magnifying endoscopy. METHOD: All patients with diagnosis of gastric MALToma upon histology were recruited. They received magnifying endoscopy to observe for changes in microstructural and microvascular patterns. For patients with H pylori, eradication therapy would be given. For those without, appropriate treatments including gastrectomy or chemotherapy were commenced accordingly...
January 2012: Journal of Interventional Gastroenterology
https://www.readbyqxmd.com/read/21686997/colonic-maltoma-a-case-report-and-review-of-the-literature
#6
Lawrence Toquero, Omar M Aboumarzouk, Sandro Lanzon-Miller
Gastric mucosa associated lymphoid tissue lymphomas (MALTomas) are well-documented and their management effectively established, but colonic MALTomas are extremely rare and not many know it could occur. We report the first colonic MALToma in the UK. The patient was managed in accordance with gastric MALToma management modalities in accordance with the evidence in the literature. After failure of medical management, a surgical resection was the last and successful option for treatment.Though gastric MALToma management is well-established, the colonic form of the disease does not act the same and requires a more aggressive approach...
2009: BMJ Case Reports
https://www.readbyqxmd.com/read/21199513/helicobacter-pylori-and-gastritis-untangling-a-complex-relationship-27-years-on
#7
REVIEW
Victoria P Y Tan, Benjamin C Y Wong
Since its' introduction by Warren and Marshall 27 years ago, Helicobacter pylori (HP) has become the linchpin in our understanding of important gastric conditions including gastritis, intestinal metaplasia (IM), gastric/duodenal ulcers (GU/DU), Mucosal Associated Lymphoid Tumour (MALToma) and gastric cancer. Initially named Campylobacter pyloridis, it was re-named HP when biochemical and genetic characterization of the organism showed that it was not a member of the Campylobacter genus. The finding in 1983 was seminal...
January 2011: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/20610148/early-low-grade-gastric-maltoma-rarely-transforms-into-diffuse-large-cell-lymphoma-or-progresses-beyond-the-stomach-and-regional-lymph-nodes
#8
Ting-Yun Liu, Pei-Han Dei, Sung-Hsin Kuo, Chung-Wu Lin
BACKGROUND/PURPOSE: Gastric mucosa-associated lymphoid tissue lymphoma (MALToma) usually presents at an early stage involving only the stomach and/or regional lymph nodes. Although a sequential transformation from low-grade gastric MALToma (GM) to high-grade GM to secondary diffuse large B-cell lymphoma (DLBCL) is commonly assumed, documented cases of transformation are rare. We aim to determine the frequency of transformation. METHODS: We identified 55 early low-grade GMs, 18 early high-grade GMs, and 13 advanced GMs at the National Taiwan University Hospital from 1995 to 2005...
June 2010: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/19169609/helicobacter-pylori-infection-and-gastric-maltomas-an-up-to-date-and-therapy-highlight
#9
REVIEW
L Santacroce, R Cagiano, R Del Prete, L Bottalico, R Sabatini, R G Carlaio, R Prejbeanu, H Vermesan, S I Dragulescu, D Vermesan, A Motoc, T Losacco
During the last 20 years Helicobacter pylori (Hp) has been, undoubtly, the star of gastroenterology and microbiology, so much to deserve the "Nobel prize 2005" for biology and medicine to its discoverers. More recently, an increased interest arised on Hp and its linkages with other medical fi elds such as immunology, surgery and dentistry. The outcome of the pathologies due to such bacterium is dependent on many factors, including bacterial genotype, host physiology and genetics, and environmental factors such as diet...
November 2008: La Clinica Terapeutica
https://www.readbyqxmd.com/read/18776980/our-experience-in-helicobacter-pylori-infection-and-gastric-maltoma
#10
T Losacco, R Cagiano, L Bottalico, R G Carlaio, R Prejbeanu, H Vermesan, S I Dragulescu, D Vermesan, A Motoc, L Santacroce
OBJECTIVE: A number of recent studies have expanded our understanding of Helicobacter pylori (Hp) infection and of the pathogenesis of MALT lymphoma. The purpose of this paper is to perform a retrospective analysis of the clinical characteristics of gastric MALT lymphoma and its relationship with H. pylori infection in authors' experience. MATERIALS AND METHODS: We report nineteen patients observed during 10 years, presenting with gastric MALTomas at any stage. The staging classification and the presence of H...
July 2008: La Clinica Terapeutica
https://www.readbyqxmd.com/read/18241627/helicobacter-pylori-vaccine-from-past-to-future
#11
REVIEW
Kanishtha Agarwal, Shvetank Agarwal
Helicobacter pylori infection is highly prevalent worldwide and is an important cause of gastritis, peptic ulcer disease, gastric mucosa-associated lymphoid tissue lymphoma (MALToma), and gastric adenocarcinoma. Infection is usually acquired during childhood and tends to persist unless treated. Because eradication requires treatment with multidrug regimens, prevention of initial infection by a suitable vaccine is attractive. Although immunization with H pylori protein subunits has been encouraging in animals, similar vaccine trials in humans have shown adjuvant-related adverse effects and only moderate effectiveness...
February 2008: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/18052867/antibiotic-resistance-of-helicobacter-pylori-from-patients-in-ile-ife-south-west-nigeria
#12
Oladiipo A Aboderin, Abdul R Abdu, Babatunde 'Wumi Odetoyin, Iruka N Okeke, Oladejo O Lawal, Dennis A Ndububa, Augustine E Agbakwuru, Adebayo Lamikanra
BACKGROUND: Helicobacter pylori has become recognized as a major cause of gastroduodenal diseases in man. Evidence indicates that once acquired, H. pylori persists, usually for life unless eradicated by antimicrobial therapy. Over the past few years, we have accumulated some knowledge of the epidemiology of H. pylori in Ile-Ife, South-West Nigeria. In one collaborative study, we detected H. pylori in 195 (73%) patients referred for endoscopy at Obafemi Awolowo University Teaching Hospitals Complex (OAUTHC)...
September 2007: African Health Sciences
https://www.readbyqxmd.com/read/17883049/primary-gastrointestinal-lymphoma-a-clinicopathologic-study
#13
Kaushambi Shukla, Trupti Patel, Jaimini Shukla, Satya Palanki
Gastrointestinal tract is the most common site for the development ofextra nodal lymphoma. This study was done to analyze clinical and pathological features as well as the treatment outcome of this disease. We carried out analysis of25 cases of primary gastrointestinal (GI) lymphomas during period from March 2001 to February 2003 at Gujarat Cancer & Research Institute. Out of 25 cases of primary GI lymphoma, nine cases of gastric lymphoma, nine cases of small intestinal lymphoma and seven cases of large intestinal lymphoma were identified...
April 2007: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/17517178/diagnosis-and-treatment-of-pulmonary-mucosa-associated-lymphoid-tissue-lymphoma
#14
He-Yun Xu, Tao Jin, Ren-Yuan Li, Yi-Ming Ni, Jian-Ying Zhou, Xiao-Hong Wen
BACKGROUND: Primary non-Hodgkin's lymphoma in lung is very rare, and the most common among them is mucosa-associated lymphoid tissue lymphoma (MALToma), whose clinical features and laboratory characteristics are poorly defined, making diagnosis difficult. The purpose of this study was to study the diagnosis and treatment of pulmonary MALToma. METHODS: The clinical data of 12 patients treated for MALToma between August 1992 and December 2005 were analyzed. RESULTS: No specific symptoms or signs, or results of bronchoscopy, ultrasonagraphy or bone marrow examination could be found in the 12 patients...
April 20, 2007: Chinese Medical Journal
https://www.readbyqxmd.com/read/17200353/risk-of-second-cancer-in-nongastric-marginal-zone-b-cell-lymphomas-of-mucosa-associated-lymphoid-tissue-a-population-based-study-from-northern-italy
#15
Luca Arcaini, Sara Burcheri, Andrea Rossi, Cristiana Pascutto, Francesco Passamonti, Ercole Brusamolino, Marco Paulli, Ester Orlandi, Maurizio Buelli, Piera Viero, Marco Lucioni, Francesca Montanari, Michele Merli, Sergio Cortelazzo, Mario Lazzarino
PURPOSE: The aim of this study was to define the risk of second cancer in nongastric marginal zone lymphomas of mucosa-associated lymphoid tissue (MALT). EXPERIMENTAL DESIGN: We considered for the analysis 157 patients with a confirmed histology of marginal zone B-cell lymphoma of MALT, presenting with a clinically prevalent extranodal site of disease, except for stomach. All patients came from two hematologic institutions of Northern Italy. We compared the occurrence of second cancer with respect to the general population by calculating the standardized incidence ratio, with the age- and sex-specific incidence rates of a cancer registry of Northern Italy (Lombardia) as a reference...
January 1, 2007: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/17164171/helicobacter-pylori-profile-in-asymptomatic-farmers-and-non-farmers
#16
Abdulbari Bener, Edward O Adeyemi, Ahmed M Almehdi, Abdulmajeed Ameen, Mehra Beshwari, Sheila Benedict, Moutaz F Derballa
There is a positive correlation between Helicobacter pylori infection and chronic active gastritis, peptic ulcer and gastric cancer and maltoma. There is little information on H. pylori profiles in farmers and non-farmers in the literature. Our main objective was to study the H. pylori profiles in farmers and non-formers in the United Arab Emirates. A prospective study of 151 subjects - 76 farmers and 75 non-farmers - was undertaken by determining their IgG and IgA H. pylori antibody profiles in their serum samples...
December 2006: International Journal of Environmental Health Research
https://www.readbyqxmd.com/read/16880064/helicobacter-pylori-diagnosis-and-management
#17
REVIEW
Ratha-Korn Vilaichone, Varocha Mahachai, David Y Graham
H pylori is a global human pathogen and is the major cause of gastritis and the gastritis-associated diseases: gastric ulcer, duodenal ulcer, gastric cancer, and primary gastric B-cell lymphoma (MALToma). Although several reliable diagnostic tests are widely available, the ideal regimen for treating the infection re-mains to be established. The current first-line or legacy triple therapy regimens fail in 20% to 40% of patients. Causes of treatment failure include antibiotic resistance, poor compliance, short (7-10 days) duration of therapy, and drug-related side effects...
June 2006: Gastroenterology Clinics of North America
https://www.readbyqxmd.com/read/15069707/clinicopathologic-features-of-surgically-resected-primary-gastric-lymphoma
#18
Seong-Ho Kong, Min-A Kim, Do-Joong Park, Hyuk-Joon Lee, Hye-Seung Lee, Chul-Woo Kim, Han-Kwang Yang, Dae-Seog Heo, Kuhn-Uk Lee, Kuk-Jin Choe
AIM: To analyze the clinicopathologic characteristics of surgically resected gastric lymphoma patients. METHODS: We retrospectively analyzed 57 surgically resected gastric lymphoma patients, dividing them into 2 subgroups: Low grade MALToma (the LG group), High grade MALToma and Diffuse large B cell lymphoma (the HG group). RESULTS: The numbers of patients were: 20 in the LG group, 37 in the HG group. The diagnostic rate of gastroscopy was 34...
April 15, 2004: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/14716827/low-grade-gastric-mucosa-associated-lymphoid-tissue-lymphoma-treatment-strategies-based-on-10-year-follow-up
#19
Sang Kil Lee, Yong Chan Lee, Jae Bock Chung, Chae Yoon Chon, Young Myoung Moon, Jin Kyung Kang, In-Suh Park, Chang Ok Suh, Woo Ik Yang
AIM: To deduce strategic guidelines of gastric mucosa associated lymphoid tissue lymphoma (MALTOMA) by evaluating the long-term outcome of patients in respect to various treatment modalities. METHODS: A total of 55 patients with MALTOMA from May 1992 to August 2002 were retrospectively reviewed. RESULTS: Complete remission was obtained in 24 (82.8%) of 29 patients treated with anti Helicobacter pylori (H pylori) regimen only. The duration to reach complete remission was 12 months (85 percentile, 2-33 months)...
January 15, 2004: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/12920824/-analysis-of-37-pathological-and-clinic-data-of-extranodal-marginal-zone-b-cell-lymphoma-of-mucosa-associated-lymphoid-tissue-malt
#20
Xiaoyan Ke, Hongmei Jing, Min Li, Xiuyun An, Zifen Gao
OBJECTIVE: To provide pathological and clinical evidences in order to establish standardized diagnosis and treatment for MALT lymphoma. METHODS: Pathological characters, grade, stage, prognostic factors and treatment of 37 cases of MALT lymphoma were analyzed which were diagnosed from January 2000 to June 2002. RESULTS: The 39 patients(8.82%) were diagnosed as MALT lymphoma out of 442 NHL patients(37 patients were followed up, and two missing)...
April 18, 2003: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
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