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https://www.readbyqxmd.com/read/28231598/evaluation-of-the-p16-and-ki-67-biomarkers-as-predictors-of-the-recurrence-of-premalignant-cervical-cancer-lesions-after-leep-conization
#1
Paulo Macêdo de Oliveira Leite, Luciene Tafuri, Maria Zélia de Oliveira Costa, Maria Inês de Miranda Lima, Renata Toscano Simões
Objective To evaluate the expressions of biomarkers p16 and Ki-67 in low-grade (LG) or high-grade (HG) lesions, and to relate them to risk factors and the recurrence of these lesions. Methods A retrospective case-control study of 86 patients with LG and HG lesions who underwent a loop electrosurgical excision procedure (LEEP) between 1999 and 2004. The control group was composed of 69 women with no recurrence, and the study group, of 17 patients with recurrence. All patients were followed-up over a two-year period after surgery, and screened every six months, including cytology and colposcopy...
February 23, 2017: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/28227186/aart-bc-a-sensor-system-for-monitoring-assistive-technology-use-beyond-the-clinic
#2
Christopher J James, James D Amor, Catherine Holloway, Tsu-Jui Cheng, Laurence Kenney, Christopher J James, James D Amor, Catherine Holloway, Tsu-Jui Cheng, Laurence Kenney, Tsu-Jui Cheng, Laurence Kenney, Christopher J James, Catherine Holloway, James D Amor
A wide range of assistive and rehabilitative technologies (ART) are available to assist with mobility and upper limb function. However, anecdotal evidence suggests many of the devices prescribed, or purchased, are either poorly used, or rejected entirely. This situation is costly, both for the healthcare provider and the user, and may be leading to secondary consequences, such as falls and/or social isolation. This paper reports on the development and initial feasibility testing of a system for monitoring when and how assistive devices are used outside of the clinic setting, and feeding this information to the device user themselves and/or prescribing clinician (where appropriate)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28223741/changing-in-the-epidemiology-of-tinea-capitis-among-school-children-in-egypt
#3
Rasha H Bassyouni, Naglaa A El-Sherbiny, Talal A Abd El Raheem, Basma H Mohammed
BACKGROUND: Tinea capitis remains a prevalent health problem among school-aged children. OBJECTIVE: To estimate the prevalence of tinea capitis among primary school students, in Fayoum, Egypt with identification of etiological agents in both public and private primary schools. METHODS: A cross-sectional study was conducted in twelve primary schools. The students were selected from different grades with a total number of 12,128 students. Hair and scalp were clinically examined for any lesions that may suspect tinea capitis and mycological samples were collected for direct microscopy and culture...
February 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28222827/health-risk-appraisal-in-older-people-7-long-acting-benzodiazepine-use-in-community-dwelling-older-adults-in-london-is-it-related-to-physical-or-psychological-factors
#4
Devoshree Chatterjee, Steve Iliffe, Kalpa Kharicha, Danielle Harari, Cameron Swift, Gerhard Gillman, Andreas E Stuck
: Aim To investigate whether the use of long-acting benzodiazepines, in individuals aged 65 and over is mediated by physical or psychological factors. BACKGROUND: Long-acting benzodiazepine consumption among older people has implications for mortality, morbidity and cost-effective prescribing. Two models explain benzodiazepine use in this age group, one linked to physical illness and disability and one to psychological factors. METHODS: Secondary analysis of baseline data from a study of 1059 community-dwelling non-disabled people aged 65 years and over recruited from three general practices in London...
February 22, 2017: Primary Health Care Research & Development
https://www.readbyqxmd.com/read/28222237/extreme-genetic-structure-in-a-social-bird-species-despite-high-dispersal-capacity
#5
Francisco Morinha, José A Dávila, Estela Bastos, João A Cabral, Óscar Frías, José L González, Paulo Travassos, Diogo Carvalho, Borja Milá, Guillermo Blanco
Social barriers have been shown to reduce gene flow and contribute to genetic structure among populations in species with high cognitive capacity and complex societies, such as cetaceans, apes and humans. In birds, high dispersal capacity is thought to prevent population divergence unless major geographic or habitat barriers induce isolation patterns by dispersal, colonization or adaptation limitation. We report that Iberian populations of the red-billed chough, a social, gregarious corvid with high dispersal capacity, show a striking degree of genetic structure composed of at least 15 distinct genetic units...
February 21, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28222189/molecular-epidemiology-of-mycobacterium-tuberculosis-complex-in-brussels-2010-2013
#6
Christelle Vluggen, Karine Soetaert, Guido Groenen, Maryse Wanlin, Martine Spitaels, Wouter Arrazola de Oñate, Maryse Fauville-Dufaux, Claude Saegerman, Vanessa Mathys
The tuberculosis (TB) incidence rate in Brussels-Capital Region is 3-fold higher than in Belgium as a whole. Eight years after the realization of initial prospective population-based molecular epidemiology investigations in this Region, a similar study over the period 2010-2013 was conducted. TB strains isolated from 945 patients were submitted to genotyping by standardized 24-locus-MIRU-VNTR typing and spoligotyping. The phylogenetic analysis showed that the LAM (16.7%) and Haarlem (15.7%) branches are the two most prevalent TB lineages circulating in Brussels...
2017: PloS One
https://www.readbyqxmd.com/read/28221835/social-information-on-fear-and-food-drives-animal-grouping-and-fitness
#7
Michael A Gil, Zachary Emberts, Harrison Jones, Colette M St Mary
Empirical studies in select systems suggest that social information-the incidental or deliberate information produced by animals and available to other animals-can fundamentally shape animal grouping behavior. However, to understand the role of social information in animal behavior and fitness, we must establish general theory that quantifies effects of social information across ecological contexts and generates expectations that can be applied across systems. Here we used dynamic state variable modeling to isolate effects of social information about food and predators on grouping behavior and fitness...
March 2017: American Naturalist
https://www.readbyqxmd.com/read/28220660/sarcoma-survivors-perspectives-on-their-body-image-and-functional-quality-of-life-post-resection-limb-salvage-surgery
#8
Myra F Taylor, Julie A Pooley
Sarcomas often occur in patients' extremities and treatment typically involves bone resection/limb salvage surgery. Such treatments leave survivors with physical disfigurements, functional disabilities, and/or emotional traumas. Our post-surgery psychological intervention investigated how these experiences impinge on sarcoma survivors' lives. Twenty-three survivors aged 19-60 years (M = 36 years) participated in a tri-disciplinary (rehabilitative exercise, plastic surgery and psychological) intervention...
February 21, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28220087/mental-state-understanding-in-children-with-agenesis-of-the-corpus-callosum
#9
Beatrix Lábadi, Anna M Beke
Impaired social functioning is a well-known outcome of individuals with agenesis of the corpus callosum. Social deficits in nonliteral language comprehension, humor, social reasoning, and recognition of facial expression have all been documented in adults with agenesis of the corpus callosum. In the present study, we examined the emotional and mentalizing deficits that contributing to the social-cognitive development in children with isolated corpus callosum agenesia, including emotion recognition, theory of mind, executive function, working memory, and behavioral impairments as assessed by the parents...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28219403/the-kiva-antibullying-program-in-primary-schools-in-chile-with-and-without-the-digital-game-component-study-protocol-for-a-randomized-controlled-trial
#10
Jorge Gaete, Daniela Valenzuela, Cristian Rojas-Barahona, Eduardo Valenzuela, Ricardo Araya, Christina Salmivalli
BACKGROUND: Bullying is a major problem worldwide and Chile is no exception. Bullying is defined as a systematic aggressive behavior against a victim who cannot defend him or herself. Victims suffer social isolation and psychological maladjustment, while bullies have a higher risk for conduct problems and substance use disorders. These problems appear to last over time. The KiVa antibullying program has been evaluated in Finland and other European countries, showing preventive effects on victimization and self-reported bullying...
February 20, 2017: Trials
https://www.readbyqxmd.com/read/28218982/isolation-and-prayer-as-means-of-solace-for-arab-women-with-breast-cancer-an-in-depth-interview-study
#11
Ghada Najjar Assaf, Eleanor Holroyd, Violeta Lopez
OBJECTIVE: This study explored Arab women's experiences following the diagnosis and treatment of breast cancer. METHODS: Face-to-face in-depth interviews were conducted with 20 Arab women attending a public hospital in Abu Dhabi, United Arab Emirates following a recent diagnosis of breast cancer. All interviews were transcribed verbatim and analysed using the thematic method. RESULTS: Arab women's experiences following their breast cancer diagnoses and treatments included the themes of: (1) protecting one's self from stigma, (2) facing uncertainties, and prayers, and (3) getting on with life...
February 20, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28218471/%C3%AE-4%C3%AE-%C3%AE-gabaa-receptors-in-dorsal-hippocampal-ca1-of-adolescent-female-rats-traffic-to-the-plasma-membrane-of-dendritic-spines-following-voluntary-exercise-and-contribute-to-protection-of-animals-from-activity-based-anorexia-through-localization-at-excitatory
#12
Chiye Aoki, Yi-Wen Chen, Tara Gunkali Chowdhury, Walter Piper
In hippocampal CA1 of adolescent female rodents, α4βδ-GABAA receptors (α4βδ-GABAA Rs) suppress excitability of pyramidal neurons through shunting inhibition at excitatory synapses. This contributes to anxiolysis of stressed animals. Socially isolated adolescent female rats with 8 days of wheel access, the last 4 days of which entail restricted food access, have been shown to exhibit excessive exercise, choosing to run instead of eat (activity-based anorexia [ABA]). Upregulation of α4βδ-GABAA Rs in the dorsal hippocampal CA1 (DH), seen among some ABA animals, correlates with suppression of excessive exercise...
February 20, 2017: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/28216815/gracilis-muscle-transposition-as-a-workhorse-flap-for-anal-incontinence-quality-of-life-and-functional-outcome-in-adults
#13
Guru Dayal Singh Kalra, Amit Kumar Sharma, Kaustubh Sharad Shende
BACKGROUND/PURPOSE: Anal incontinence is one of the most psychologically and socially debilitating conditions in an otherwise healthy individual. It can lead to social isolation, loss of self-esteem, self-confidence and depression. This study is devoted to the problem of anal incontinence in the adult patients. The aim of our study is to analyse the results of gracilis muscle transposition for anal incontinence and improvement in quality of life (QOL) of patients. MATERIALS AND METHODS: This was a retrospective study...
September 2016: Indian Journal of Plastic Surgery: Official Publication of the Association of Plastic Surgeons of India
https://www.readbyqxmd.com/read/28216097/epidemiology-and-resistance-characteristics-of-pseudomonas-aeruginosa-isolates-from-the-respiratory-department-of-a-hospital-in-china
#14
Wei Feng, Fengjun Sun, Qian Wang, Wei Xiong, Xuewen Qiu, Xiaotian Dai, Peiyuan Xia
OBJECTIVES: Pseudomonas aeruginosa is one of the most common pathogens causing nosocomial pneumonia. The aim of this study was to investigate the epidemiology and resistance of P. aeruginosa isolated from hospitalised patients in the respiratory department of a hospital in China. METHODS: Clinical isolates were collected from the respiratory department of Southwest Hospital (Chongqing, China) from January 2013 to December 2014. Patients' social and demographic information was obtained from the hospital's information system...
February 12, 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/28215871/disease-behaviours-of-sows-naturally-infected-with-taenia-solium-in-tanzania
#15
Chiara Trevisan, Maria Vang Johansen, Ernatus Martin Mkupasi, Helena Aminel Ngowi, Björn Forkman
Neurocysticercosis (NCC) is a disease caused by the zoonotic parasite Taenia solium lodging in the central nervous system. Both humans and pigs can get NCC. The impact of the disease in pigs has so far been little explored. The aim of this study was to describe the effect of NCC on social and feeding behaviours as well as the pattern of activity as indicators of reduced welfare in naturally infected sows. In total 13 T. solium naturally infected and 15 non-infected control sows were videotaped for 2 consecutive weeks using close circuit television cameras at research facilities at Sokoine University of Agriculture, Morogoro, Tanzania...
February 15, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28213169/functional-outcomes-in-community-based-adults-with-borderline-personality-disorder
#16
Kristin N Javaras, Mary C Zanarini, James I Hudson, Shelly F Greenfield, John G Gunderson
Many individuals in clinical samples with borderline personality disorder (BPD) experience high levels of functional impairment. However, little is known about the levels of functional impairment experienced by individuals with BPD in the general community. To address this issue, we compared overall and domain-specific (educational/occupational; social; recreational) functioning in a sample of community-based individuals with BPD (n = 164); community-based individuals without BPD (n = 901); and clinically-ascertained individuals with BPD (n = 61)...
January 24, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28210860/a-heat-vulnerability-index-to-improve-urban-public-health-management-in-san-juan-puerto-rico
#17
Pablo Méndez-Lázaro, Frank E Muller-Karger, Daniel Otis, Matthew J McCarthy, Ernesto Rodríguez
Increased frequency and length of high heat episodes are leading to more cardiovascular issues and asthmatic responses among the population of San Juan, the capital of the island of Puerto Rico, USA. An urban heat island effect, which leads to foci of higher temperatures in some urban areas, can raise heat-related mortality. The objective of this research is to map the risk of high temperature in particular locations by creating heat maps of the city of San Juan. The heat vulnerability index (HVI) maps were developed using images collected by satellite-based remote sensing combined with census data...
February 17, 2017: International Journal of Biometeorology
https://www.readbyqxmd.com/read/28209168/the-impact-of-preterm-birth-37%C3%A2-weeks-on-parents-and-families-a-cross-sectional-study-in-the-2%C3%A2-years-after-discharge-from-the-neonatal-intensive-care-unit
#18
Ashwini Lakshmanan, Meghana Agni, Tracy Lieu, Eric Fleegler, Michele Kipke, Philippe S Friedlich, Marie C McCormick, Mandy B Belfort
BACKGROUND: Little is known about the quality of life of parents and families of preterm infants after discharge from the neonatal intensive care unit (NICU). Our aims were (1) to describe the impact of preterm birth on parents and families and (2) and to identify potentially modifiable determinants of parent and family impact. METHODS: We surveyed 196 parents of preterm infants <24 months corrected age in 3 specialty clinics (82% response rate). Primary outcomes were: (1) the Impact on Family Scale total score; and (2) the Infant Toddler Quality of Life parent emotion and (3) time limitations scores...
February 16, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28205363/health-related-quality-of-life-after-combined-liver-and-kidney-transplantation-in-children
#19
Kaja Schmaeschke, Susanne Lezius, Enke Grabhorn, Markus J Kemper, Florian Brinkert
While reduced HRQOL following isolated organ transplantation has been previously reported, there are no data in the context of children following CLKT. Twenty-three children who underwent CLKT at our institution were included in the study. The indication for CLKT was PH1 in 13 patients and ARPKD in 10 patients. Quantification of HRQOL was facilitated through the use of the PedsQL 4.0 Generic Core Scale. The results of the study were compared to healthy children and published data of children who had undergone LTx or KTx...
February 15, 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/28204992/the-life-experience-of-nutrition-impact-symptoms-during-treatment-for-head-and-neck-cancer-patients-a-systematic-review-and-meta-synthesis
#20
REVIEW
Valentina Bressan, Annamaria Bagnasco, Giuseppe Aleo, Gianluca Catania, Milko P Zanini, Fiona Timmins, Loredana Sasso
PURPOSE: In the literature, there is limited research about the changed meaning of food, the eating and the eating experience during treatment in patients with head and neck cancer. This systematic review includes findings from a qualitative research synthesis to gain a deeper understanding of the influence and experiences of dysphagia, dysgeusia, oral mucositis and xerostomia in head and neck cancer patients (HNC) and suggests recommendations for care practice. METHOD: A systematic review and meta-synthesis techniques were adopted to identify, appraise and synthesize the relevant literature regarding the experience of nutritional symptoms of HNC patients conducted according to the PRISMA guidelines...
February 15, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
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