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https://www.readbyqxmd.com/read/29768326/chronic-constipation-a-review-of-literature
#1
Mojgan Forootan, Nazila Bagheri, Mohammad Darvishi
BACKGROUND: Chronic constipation is described as a common complication determined by difficult and/or rare passage of stool or both. The difference in definition of constipation has led to a wide range of reported prevalence (i.e., between 1% and 80%). Various factors are involved in the pathogenesis of the disease, including type of diet, genetic predisposition, colonic motility, absorption, social economic status, daily behaviors, and biological and pharmaceutical factors. Diagnostic and therapeutic options play a key role in the treatment of chronic constipation...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29765332/galectin-9-expression-predicts-favorable-clinical-outcome-in-solid-tumors-a-systematic-review-and-meta-analysis
#2
Xiaoxiang Zhou, Lejia Sun, Dan Jing, Gang Xu, Jinmei Zhang, Li Lin, Jingjing Zhao, Zhuoran Yao, Hongfeng Lin
Background and Objective: Galectin-9 (Gal-9) is one of the galectin family members which are known as proteins with β-galactoside-binding affinity. Accumulative evidence suggest that Gal-9 plays multifaceted roles in tumor biology. However, the prognostic significance of Gal-9 in solid cancer patients remains controversial. The objective of the study was to clarify the prognostic significance of Gal-9 in solid tumors via meta-analysis. Methods: We searched PubMed, Embase and the Cochrane library for studies that report the correlation between Gal-9 expression and prognosis or clinicopathological parameters in solid cancer patients from inception to October 2017, with no language restriction...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29757939/heterogeneity-in-the-relationship-between-disinfection-by-products-in-drinking-water-and-cancer-a-systematic-review
#3
Tarik Benmarhnia, Ianis Delpla, Lara Schwarz, Manuel J Rodriguez, Patrick Levallois
The epidemiological evidence demonstrating the effect of disinfection by-products (DBPs) from drinking water on colon and rectal cancers is well documented. However, no systematic assessment has been conducted to assess the potential effect measure modification (EMM) in the relationship between DBPs and cancer. The objective of this paper is to conduct a systematic literature review to determine the extent to which EMM has been assessed in the relationship between DBPs in drinking water in past epidemiological studies...
May 14, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29756013/colonic-stent-versus-emergency-surgery-as-treatment-of-malignant-colonic-obstruction-in-the-palliative-setting-a-systematic-review-and-meta-analysis
#4
REVIEW
Igor Braga Ribeiro, Wanderley Marques Bernardo, Bruno da Costa Martins, Diogo Touriani Hourneau de Moura, Elisa Ryoka Baba, Iatagan Rocha Josino, Nelson Tomio Miyahima, Martin Andrés Coronel Cordero, Thiago Arantes de Carvalho Visconti, Edson Ide, Paulo Sakai, Eduardo Guimarães Hourneau de Moura
Background and study aims : Colorectal cancer (CRC) is the third most common malignancy and the third leading cause of cancer death worldwide. Malignant colonic obstruction (MCO) due to CRC occurs in 8 % to 29 % of patients.The aim of this study was to perform a systematic review and meta-analysis of RCTs comparing colonic SEMS versus emergency surgery (ES) for MCO in palliative patients. This was the first systematic review that included only randomized controlled trials in the palliative setting...
May 2018: Endoscopy International Open
https://www.readbyqxmd.com/read/29739349/what-is-the-result-of-vaginal-cleansing-with-chlorhexidine-during-labour-on-maternal-and-neonatal-infections-a-systematic-review-of-randomised-trials-with-meta-analysis
#5
Charlotte Bell, Laura Hughes, Trevor Akister, Vin Ramkhelawon, Amie Wilson, David Lissauer
BACKGROUND: Infection with vaginal microorganisms during labour can lead to maternal and neonatal mortality and morbidity. The objective of this systematic review is to review the effectiveness of intrapartum vaginal chlorhexidine in the reduction of maternal and neonatal colonisation and infectious morbidity. METHODS: Search strategy - Eight databases were searched for articles published in any language from inception to October 2016. Selection criteria - Randomised controlled trials were included...
May 8, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29731953/adrenal-insufficiency-in-cystic-fibrosis-a-rare-phenomenon
#6
Sébastien Préville-Ratelle, Adèle Coriati, Aurélie Ménard, Isabelle Bourdeau, François Tremblay, Yves Berthiaume
Background: The prevalence of adrenal insufficiency (AI) in cystic fibrosis (CF) is unknown. The frequent use of glucocorticoids (inhaled or systemic) may induce the long-term suppression of the hypothalamic-pituitary-adrenal axis. Methods: We reviewed the results of adrenocorticotropic hormone (ACTH) stimulation tests done over a 10-year period to evaluate adrenal function in 69 CF patients of the CHUM CF clinic. Clinical characteristics of AI patients were compared to adrenal-sufficient (AS) patients...
2018: Canadian Respiratory Journal: Journal of the Canadian Thoracic Society
https://www.readbyqxmd.com/read/29721198/global-burden-of-neuroendocrine-tumors-and-changing-incidence-in-kentucky
#7
Aman Chauhan, Qian Yu, Neha Ray, Zainab Farooqui, Bin Huang, Eric B Durbin, Thomas Tucker, Mark Evers, Susanne Arnold, Lowell B Anthony
Background: Neuroendocrine tumors (NETs) have a low incidence but relatively high prevalence. Over the last three decades, the incidence of NETs has risen 6-fold in the United States. We conducted an observational study to compare the incidence of NETs reported to the Kentucky Cancer Registry (KCR) versus that reported to Surveillance, Epidemiology, and End Results Program (SEER). We also provide a systematic review of the state of neuroendocrine tumors worldwide, and compare the available global and local published data...
April 10, 2018: Oncotarget
https://www.readbyqxmd.com/read/29713184/prognostic-and-clinicopathological-value-of-sirt3-expression-in-various-cancers-a-systematic-review-and-meta-analysis
#8
Yongping Zhou, Sijin Cheng, Sinuo Chen, Yongzhao Zhao
Background: Several studies have explored the prognostic value of sirtuin 3 (SIRT3) in various cancers, but obtained inconsistent results. The current systematic review and meta-analysis was conducted to investigate the association between SIRT3 expression and prognosis in various cancers. Methods: PubMed, Embase, Web of Science and the Cochrane Library were comprehensively retrieved by the end of September 29, 2017. All the relevant studies were checked and included in the meta-analysis if they met the inclusion criteria...
2018: OncoTargets and Therapy
https://www.readbyqxmd.com/read/29708771/serratia-marcescens-colonization-causing-pink-breast-milk-and-pink-diapers-a-case-report-and-literature-review
#9
Laura Quinn, Melody Ailsworth, Elizabeth Matthews, Ann Kellams, Debbie-Ann Shirley
INTRODUCTION: Serratia marcescens is an opportunistic pathogen and common cause of infectious outbreaks in pediatric units, leading to both significant morbidity and mortality in immunocompromised hosts. Environmental and some clinical strains may produce a characteristic red pigment, prodigiosin. Colonization can hence turn breast milk and fecally-soiled diapers pink, which can lead otherwise unaffected patients to present to their physicians and also interrupt breastfeeding. No clear guidance exists regarding the outpatient management of breastfeeding mothers and infants colonized with S...
April 30, 2018: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/29706374/risk-of-gastrointestinal-cancers-in-patients-with-cystic-fibrosis-a-systematic-review-and-meta-analysis
#10
Akihiro Yamada, Yuga Komaki, Fukiko Komaki, Dejan Micic, Samantha Zullow, Atsushi Sakuraba
BACKGROUND: The management and life expectancy of patients with cystic fibrosis have improved substantially in the past three decades, which has resulted in an increased number of these patients being diagnosed with malignancies. Our aim was to assess the risk of gastrointestinal cancers in patients with cystic fibrosis. METHODS: In this systematic review and meta-analysis, we searched PubMed, MEDLINE, Google Scholar, Scopus, Embase, and Cochrane databases with no language restrictions for studies published from inception of the databases to Aug 1, 2017, assessing the risk of gastrointestinal cancers in patients with cystic fibrosis...
April 26, 2018: Lancet Oncology
https://www.readbyqxmd.com/read/29705346/pancreatoduodenectomy-with-colon-resection-for-pancreatic-cancer-a-systematic-review
#11
REVIEW
Leonardo Solaini, Thijs de Rooij, E Madelief Marsman, Wouter W Te Riele, Pieter J Tanis, Thomas M van Gulik, Dirk J Gouma, Neal H Bhayani, Thilo Hackert, Olivier R Busch, Marc G Besselink
BACKGROUND: Radical resection of advanced pancreatic cancer may occasionally require a simultaneous colon resection. The risks and benefits of this combined procedure are largely unknown. This systematic review aimed to assess short and long term outcome after pancreatoduodenectomy with colon resection (PD-colon) for pancreatic ductal adenocarcinoma (PDAC). METHODS: A systematic literature search was performed in PubMed, Embase, and the Cochrane Library for studies published between 1994 and 2017 concerning PD-colon for PDAC...
April 25, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29700641/bowel-perforation-in-type-iv-vascular-ehlers-danlos-syndrome-a-systematic-review
#12
REVIEW
H El Masri, T-H Loong, G Meurette, J Podevin, F Zinzindohoue, P-A Lehur
Spontaneous gastrointestinal (GI) perforation is a well-known complication occurring in patients suffering from Type IV vascular Ehlers-Danlos syndrome (EDS IV). The aim of the present study was to review the current literature on spontaneous GI perforation in EDS IV and illustrate the surgical management and outcome when possible. A systematic review of all the published data on EDS IV patients with spontaneous GI perforation between January 2000 and December 2015 was conducted using three major databases PUBMED, EMBASE, and Cochrane Central Register of Controlled Trails...
April 26, 2018: Techniques in Coloproctology
https://www.readbyqxmd.com/read/29692043/-relationship-of-am-fungi-with-non-mycorrhizal-plants
#13
Ya Nan Chu, Hai Bo Zhang, Ze Feng Qin, Jing Ping Gai
As a kind of globally widely distributed soil microorganism, arbuscular mycorrhizal (AM) fungi form the symbiosis with the majority of land plants, which is important for plant nutrition and ecosystem functioning. Few vascular species are considered to be nonmycorrhizal, especially those within the families Amaranthaceae, Chenopodiaceae, Carophyllaceae and Brassicaceae. At present, the interactions between these non-host plants and AM fungi are few and scattered, lacking systematic summary. In this paper, the type of non-host plants, the reason of low mycotrophy, and the effect of AM network formed by neighbor plants on AM fungi colonization on the non-host, and the possible interaction between AM fungi and non-host, as well as the material exchange between plants and AM fungi and their possible ecological functions were reviewed in order to give some new ideas on the function of the nonmycorrhizal plants in the fragile ecosystems...
January 2018: Ying Yong Sheng Tai Xue Bao, the Journal of Applied Ecology
https://www.readbyqxmd.com/read/29687728/exposure-to-permethrin-and-cancer-risk-a-systematic-review
#14
Paolo Boffetta, Vimi Desai
No systematic reviews are available on data from humans on cancer risk from exposure to permethrin, a widely used insecticide for which some animal studies have reported positive findings based on mechanisms that may not be relevant to humans. We identified potentially relevant articles through a search of electronic databases which included all studies of pesticide exposure and human cancer. A total of 18 articles were selected, including six identified from the list of references of other articles. Most articles were based on analyzes of the Agriculture Health Study (AHS); they provided no evidence of an increased risk of cancers of colon, rectum, pancreas, lung, melanoma, female breast, prostate, urinary bladder, as well as non-Hodgkin lymphoma (including its main subtypes), and leukemia...
April 24, 2018: Critical Reviews in Toxicology
https://www.readbyqxmd.com/read/29669512/a-systematic-review-of-transmission-dynamic-studies-of-methicillin-resistant-staphylococcus-aureus-in-non-hospital-residential-facilities
#15
Kin On Kwok, Jonathan M Read, Arthur Tang, Hong Chen, Steven Riley, Kai Man Kam
BACKGROUND: Non-hospital residential facilities are important reservoirs for MRSA transmission. However, conclusions and public health implications drawn from the many mathematical models depicting nosocomial MRSA transmission may not be applicable to these settings. Therefore, we reviewed the MRSA transmission dynamics studies in defined non-hospital residential facilities to: (1) provide an overview of basic epidemiology which has been addressed; (2) identify future research direction; and (3) improve future model implementation...
April 18, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29667048/ethanol-lock-is-effective-on-reducing-the-incidence-of-tunneled-catheter-related-bloodstream-infections-in-hemodialysis-patients-a-systematic-review-and-meta-analysis
#16
REVIEW
Tingting Zhao, Hong Liu, Jibin Han
PURPOSE: The purpose of this meta-analysis is to evaluate the effect of ethanol lock on the incidence of catheter-related bloodstream infection (CRBSI) in patients with central venous catheters. METHODS: RCTs comparing ethanol lock with another solution lock for prevention of CRBSI were obtained by searching databases of PubMed, Embase, Web of Science and Cochrane Central Register of clinical trials for eligible randomized controlled trials (inception to December 2017)...
April 17, 2018: International Urology and Nephrology
https://www.readbyqxmd.com/read/29661109/prevalence-and-risk-factors-for-methicillin-resistant-staphylococcus-aureus-mrsa-infections-in-custodial-populations-a-systematic-review
#17
Leigh Haysom, Melanie Cross, Rebecca Anastasas, Elizabeth Moore, Stephen Hampton
Methicillin-resistant Staphylococcus aureus (MRSA) in prisons can result in serious morbidity and death. We reviewed rates and risk factors for MRSA infection in custody, searching Medline, EMBASE, and CINAHL databases. Between 1997 and 2015, 17 studies reported MRSA skin and soft tissue infections (SSTIs), with four case reports of MRSA non-SSTI (necrotizing pneumonias, brain abscess, and epiduritis). Significant associations with MRSA SSTI were found: MRSA colonization, previous skin infection, sharing soap or personal items, SSTI presenting as an abscess or furuncle, younger age, non-Caucasian, overweight, communal laundering, infrequent handwashing, lower hygiene score...
April 2018: Journal of Correctional Health Care
https://www.readbyqxmd.com/read/29617356/clostridium-bacteria-and-autism-spectrum-conditions-a-systematic-review-and-hypothetical-contribution-of-environmental-glyphosate-levels
#18
REVIEW
Isadora Argou-Cardozo, Fares Zeidán-Chuliá
Nowadays, there seems to be a consensus about the multifactorial nature of autism spectrum disorders (ASD). The literature provides hypotheses dealing with numerous environmental factors and genes accounting for the apparently higher prevalence of this condition. Researchers have shown evidence regarding the impact of gut bacteria on neurological outcomes, altering behavior and potentially affecting the onset and/or severity of psychiatric disorders. Pesticides and agrotoxics are also included among this long list of ASD-related environmental stressors...
April 4, 2018: Medical Sciences: Open Access Journal
https://www.readbyqxmd.com/read/29615487/comparison-of-prognostic-models-to-predict-the-occurrence-of-colorectal-cancer-in-asymptomatic-individuals-a-systematic-literature-review-and-external-validation-in-the-epic-and-uk-biobank-prospective-cohort-studies
#19
Todd Smith, David C Muller, Karel G M Moons, Amanda J Cross, Mattias Johansson, Pietro Ferrari, Guy Fagherazzi, Petra H M Peeters, Gianluca Severi, Anika Hüsing, Rudolf Kaaks, Anne Tjonneland, Anja Olsen, Kim Overvad, Catalina Bonet, Miguel Rodriguez-Barranco, Jose Maria Huerta, Aurelio Barricarte Gurrea, Kathryn E Bradbury, Antonia Trichopoulou, Christina Bamia, Philippos Orfanos, Domenico Palli, Valeria Pala, Paolo Vineis, Bas Bueno-de-Mesquita, Bodil Ohlsson, Sophia Harlid, Bethany Van Guelpen, Guri Skeie, Elisabete Weiderpass, Mazda Jenab, Neil Murphy, Elio Riboli, Marc J Gunter, Krasimira Jekova Aleksandrova, Ioanna Tzoulaki
OBJECTIVE: To systematically identify and validate published colorectal cancer risk prediction models that do not require invasive testing in two large population-based prospective cohorts. DESIGN: Models were identified through an update of a published systematic review and validated in the European Prospective Investigation into Cancer and Nutrition (EPIC) and the UK Biobank. The performance of the models to predict the occurrence of colorectal cancer within 5 or 10 years after study enrolment was assessed by discrimination (C-statistic) and calibration (plots of observed vs predicted probability)...
April 3, 2018: Gut
https://www.readbyqxmd.com/read/29608422/a-systematic-review-of-pericolic-extraluminal-air-in-left-sided-acute-colonic-diverticulitis
#20
Stefan T van Dijk, Sabrina A N Doelare, Anna A W van Geloven, Marja A Boermeester
BACKGROUND: Although approximately 15% of all patients with acute colonic diverticulitis have pericolic extraluminal air found on computed tomography (CT), studies on the natural course and treatment of these patients are scarce. It is not clear whether these patients behave as mild uncomplicated diverticulitis or as severe diverticulitis needing more aggressive treatment. Consequently, there is no consensus about the treatment, guidelines do not discuss this group of patients, and physicians treat these patients based on their own experiences and opinion...
April 2, 2018: Surgical Infections
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