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induction of abortion

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https://www.readbyqxmd.com/read/28807283/neospora-caninum-rop16-play-an-important-role-in-the-pathogenicity-by-phosphorylating-host-cell-stat3
#1
Lei Ma, Gongzhen Liu, Jing Liu, Muzi Li, Heng Zhang, Di Tang, Qun Liu
Neospora caninum is a common cause of abortions in cattle and nervous system dysfunctions in dogs. Our analysis shows that NcROP16 and TgROP16 have similar structures and may have similar functions. To our surprise, we found that similar to the T. gondii RH strain, the N. caninum Nc-1 strain could phosphorylate STAT3(Y705), but in contrast to T. gondii, N. caninum Nc-1 could not phosphorylate STAT6(Y641). We constructed a gene-knockout plasmid and screened ΔNcROP16 strains at the gene, protein and transcription levels...
August 30, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28793091/-maltreatment-and-discrimination-in-induced-abortion-care-perception-of-women-in-teresina-state-of-piau%C3%A3-brazil
#2
Alberto Pereira Madeiro, Andréa Cronemberger Rufino
Treatment of complications resulting from induced abortion may be hampered by discriminatory attitudes manifested by healthcare professionals in hospitals and abortion services. This article retrieved stories of institutional abuse directed at women who had an induced abortion in illegal and unsafe conditions. Seventy-eight women admitted to a public hospital in Teresina for complications after an induced abortion were interviewed. A semi-structured script was used with questions about practices and itineraries of abortion and institutional violence during hospitalization...
August 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28780483/alteration-of-the-pi3k-akt-signaling-pathway-by-swainsonine-affects-17%C3%AE-estradiol-secretion-in-ovary-cells
#3
Chenchen Wu, Dujian Yan, Dezhang Lu, Tiesuo Han, Baoyu Zhao
BACKGROUND: The ingestion of locoweed that contains the toxic indolizidine alkaloid swainsonine (SW) disrupts ovarian function, accompanied by delayed estrus, increased estrous cycle length, delayed conception, and abortion. GOALS: The direct effects of SW on ovary cell steroidogenesis remain unclear. MATERIALS AND METHODS: In this study, Chinese hamster ovary (CHO) cells were used to investigate the effects of SW on estradiol (E2) secretion and cell viability and the mechanisms involved in these processes...
July 26, 2017: Theriogenology
https://www.readbyqxmd.com/read/28780240/doing-more-for-less-identifying-opportunities-to-expand-public-sector-access-to-safe-abortion-in-south-africa-through-budget-impact-analysis
#4
N Lince-Deroche, J Harries, D Constant, C Morroni, M Pleaner, T Fetters, D Grossman, K Blanchard, E Sinanovic
OBJECTIVE(S): To estimate the costs of public-sector abortion provision in South Africa and to explore the potential for expanding access at reduced cost by changing the mix of technologies used. STUDY DESIGN: We conducted a budget impact analysis using public sector abortion statistics and published cost data. We estimated the total costs to the public health service over ten years, starting in South Africa's financial year 2016/17, given four scenarios: 1) holding service provision constant, 2) expanding public sector provision, 3) changing the abortion technologies used (i...
August 3, 2017: Contraception
https://www.readbyqxmd.com/read/28780239/-it-is-just-like-having-a-period-with-back-pain-exploring-women-s-experiences-with-community-based-distribution-of-misoprostol-for-early-abortion-on-the-thailand-burma-border
#5
Ellen Tousaw, Sweet Naw Hser Gay Moo, Grady Arnott, Angel M Foster
INTRODUCTION: The lack of economic development and longstanding conflict in Burma have led to mass population displacement. Unintended pregnancy and unsafe abortion are common and contribute to maternal death and disability. In 2011, stakeholders operating along the Thailand-Burma border established a community-based distribution program of misoprostol for early abortion, with the aim of providing safe and free abortion care in this low-resource and legally-restricted setting. METHODS: We conducted 16 in-depth, in-person interviews with women from Burma residing on both sides of the border who accessed misoprostol through the community-based distribution initiative...
August 3, 2017: Contraception
https://www.readbyqxmd.com/read/28746371/ionizing-radiation-response-of-primary-normal-human-lens-epithelial-cells
#6
Nobuyuki Hamada
Whilst the cataractogenic potential of ionizing radiation has been known for over the past 120 years, little is known about radiation responses of lens cells. Our previous work was the first to evaluate the radiosensitivity of lens cells with the clonogenic assay, documenting that the survival of HLEC1 human lens epithelial cells is comparable to that of WI-38 human lung fibroblasts. Moreover, HLEC1 cells were found to contain subsets where irradiation stimulates proliferation or facilitates formation of abortive colonies with fewer cells than human fibroblasts...
2017: PloS One
https://www.readbyqxmd.com/read/28689176/providing-experiential-information-on-early-medical-abortion-a-qualitative-evaluation-of-an-animated-personal-account-lara-s-story
#7
Sarah Sherman, Jeni Harden, Dawn Cattanach, Sharon T Cameron
BACKGROUND: An animated film has been created to provide information to women requesting early medical abortion (EMA). The 9 min film, Lara's Story, was created using one woman's personal account of her experience. This study evaluated the views of women who had recently undergone EMA on the film and its potential usefulness in providing experiential information to women requesting EMA. METHOD: Women who had undergone EMA within the past month were recruited. They were shown the film and interviewed in a semi-structured style...
July 8, 2017: Journal of Family Planning and Reproductive Health Care
https://www.readbyqxmd.com/read/28662272/campylobacter-fetus-impairs-barrier-function-in-ht-29-b6-cells-through-focal-tight-junction-alterations-and-leaks
#8
Roland Bücker, Susanne M Krug, Anja Fromm, Hans Linde Nielsen, Michael Fromm, Henrik Nielsen, Jörg-Dieter Schulzke
Infections by Campylobacter species are the most common foodborne zoonotic disease worldwide. Campylobacter jejuni and C. coli are isolated most frequently from human stool samples, but severe infections by C. fetus (Cf), which can cause gastroenteritis, septicemia, and abortion, are also found. This study aims at the characterization of pathological changes in Cf infection using an intestinal epithelial cell model. The Cf-induced epithelial barrier defects appeared earlier than those of avian Campylobacter species like C...
June 29, 2017: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/28651904/community-based-distribution-of-misoprostol-for-early-abortion-evaluation-of-a-program-along-the-thailand-burma-border
#9
Angel M Foster, Grady Arnott, Margaret Hobstetter
BACKGROUND: Although abortion is legal in Thailand for a number of indications, women from Burma residing in Thailand are rarely able to access safe services. We evaluated the outcomes of a community-based distribution program that provides migrant, refugee, and cross-border women from Burma with evidence-based information about and access to misoprostol for early pregnancy termination. METHODS: After determination of eligibility based on self-report and counseling, trained Network members instructed women to vaginally administer two 800-mcg doses of misoprostol 24 h apart and a third dose one week later, if needed...
June 23, 2017: Contraception
https://www.readbyqxmd.com/read/28645262/acute-myeloid-leukemia-and-pregnancy-clinical-experience-from-a-single-center-and-a-review-of-the-literature
#10
Nicola Stefano Fracchiolla, Mariarita Sciumè, Francesco Dambrosi, Francesca Guidotti, Manuela Wally Ossola, Giovanna Chidini, Umberto Gianelli, Daniela Merlo, Agostino Cortelezzi
BACKGROUND: Acute myeloid leukemia (AML) accounts for more than two thirds of leukemia during pregnancy and has an incidence of 1 in 75,000 to 100,000. Its clinical management remains a challenging therapeutic task both for patient and medical team, given to the therapy-attributable risks for mother and fetus and the connected counseling regarding pregnancy continuation. METHODS: We provided a review of updated literature and a comprehensive description of five maternal/fetal outcomes of AML cases diagnosed concomitantly to pregnancy and treated at our Institution from 2006 to 2012...
June 23, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28630466/comparative-effectiveness-of-9-ovulation-induction-therapies-in-patients-with-clomiphene-citrate-resistant-polycystic-ovary-syndrome-a-network-meta-analysis
#11
Yiping Yu, Lanlan Fang, Ruizhe Zhang, Jingyan He, Yujing Xiong, Xiaoyi Guo, Qingyun Du, Yan Huang, Yingpu Sun
The comparative efficacies of ovulation-induction treatments in patients with clomiphene citrate-resistant (CCR) polycystic ovary syndrome (PCOS) are not well known. Therefore, we conducted a network meta-analysis to rank the reproductive efficacies of these treatments. We ultimately included 26 randomized clinical trials with 2722 participants and 9 types of therapies: clomiphene citrate (CC), metformin, letrozole, follicle stimulating hormone (FSH), human menopausal gonadotropin (hMG), unilateral laparoscopic ovarian drilling (ULOD), bilateral laparoscopic ovarian drilling (BLOD), the combination of metformin with letrozole (metformin+letrozole), and the combination of metformin with CC (metformin+CC)...
June 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28604842/to-be-or-not-to-be-referred-a-qualitative-study-of-women-from-burma-s-access-to-legal-abortion-care-in-thailand
#12
Grady Arnott, Eh Tho, Niru Guroong, Angel M Foster
BACKGROUND: Reproductive health outcomes among women from Burma who live along the Thailand-Burma border demonstrate an unmet need for access to safe abortion services. In 2014, a multi-national team launched a collaborative three-year initiative to expand a program that refers eligible women for safe and legal abortion care to government Thai hospitals in Tak province, Thailand. METHODS: Over a six-month period we conducted 14 in-depth open-ended interviews with women from Burma who were referred through the program or denied a wanted abortion after being deemed ineligible for referral by staff at the participating clinic...
2017: PloS One
https://www.readbyqxmd.com/read/28598116/-optimal-ovulation-induction-in-polycystic-ovary-syndrome-resistant-to-clomiphene-citrate-or-letrozole
#13
Ying Chen, Dan Zhang
OBJECTIVES: To investigate the optimal ovulation induction with the combination of combining letrozole(LE),clomiphene citrate (CC),and human menopausal gonadotropin (HMG) in polycystic ovary syndrome(PCOS) patients resistant to CC or LE. METHODS: Two hundreds nine PCOS patients (209 cycles) resistant to CC or LE were randomly divided into three groups: CC+HMG group (59 cycles),LE+HMG group (72 cycles) and LE+CC group (78 cycles).The patients in LE+CC group unable to form the dominant follicle after 54 cycles were enrolled into LE+CC+HMG group...
November 2016: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/28596580/flower-induction-microscope-aided-cross-pollination-and-seed-production-in-the-duckweed-lemna-gibba-with-discovery-of-a-male-sterile-clone
#14
Lili Fu, Meng Huang, Bingying Han, Xuepiao Sun, K Sowjanya Sree, Klaus-J Appenroth, Jiaming Zhang
Duckweed species have a great potential to develop into fast-growing crops for water remediation and bioenergy production. Seed production and utilization of hybrid vigour are essential steps in this process. However, even in the extensively-studied duckweed species, Lemna gibba, flower primordia were often aborted prior to maturation. Salicylic acid (SA) and agar solidification of the medium promoted flower maturation and resulted in high flowering rates in L. gibba 7741 and 5504. Artificial cross-pollination between individuals of L...
June 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28585710/comparison-of-complications-associated-with-induction-by-misoprostol-versus-dilation-and-evacuation-for-second-trimester-abortion
#15
Sarita Sonalkar, Shannon N Ogden, Linda K Tran, Angela Y Chen
OBJECTIVE: To compare the frequency of complications between medical induction with misoprostol and dilation and evacuation (D&E) for second-trimester uterine evacuation. METHODS: In a retrospective cohort study, records were reviewed from all women who underwent second-trimester uterine evacuation between 14 and 24 weeks of pregnancy at an academic hospital in the USA from January 2007 to December 2008. Total complications and serious complications were compared between medical induction and D&E, and clinical covariates associated with complications were assessed...
September 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28557652/comparison-of-clomiphene-citrate-and-letrozole-for-ovulation-induction-in-women-with-polycystic-ovary-syndrome-a-prospective-randomized-trial
#16
Chang Liu, Guimei Feng, Wei Huang, Qiuyi Wang, Shiyuan Yang, Jing Tan, Jing Fu, Dong Liu
To compare the therapeutic efficacy of clomiphene citrate (CC) and letrozole (LE) on ovulation, pregnancy, and live birth in women with polycystic ovary syndrome (PCOS); and to ensure if LE can replace CC as the first-line therapy for ovulation induction in these women. This is a prospectively, randomized, controlled trial in the tertiary hospital. Two-hundred and sixty-eight anovulatory PCOS patients were treated by CC or CC plus metformin and LE or LE plus metformin for three continuous cycles or conception; their ovulation rates, pregnancy rates, and live birth rates were calculated and compared...
May 30, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28551840/pregnancy-after-endometrial-scratching-in-infertile-couples-undergoing-ovulation-induction-and-intrauterine-insemination-cycles-a-randomized-controlled-trial
#17
Tuhina Goel, Reeta Mahey, Neerja Bhatla, Mani Kalaivani, Sangeeta Pant, Alka Kriplani
PURPOSE: To study the effect of endometrial scratching in infertile couples undergoing ovulation induction and intrauterine insemination (IUI) cycles. METHODS: A prospective randomized controlled trial was conducted in the Department of Obstetrics and Gynaecology, AIIMS, New Delhi, India. One hundred forty-four women with primary/secondary infertility were recruited. Couples were either unexplained or male factor infertility. Subjects were randomized into intervention (scratching) and control group...
August 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28539276/-expectant-therapy-versus-curettage-for-retained-products-of-conception-after-second-trimester-termination-of-pregnancy-analysis-of-outcomes-and-complications
#18
Wen-Juan Zeng, Sheng-Li An, Hao Huang, Qi-Tao Huang, Fei-Feng Li, Hai-Zhen Wang, Dan-Chun Cai, Yun-Fei Gao
OBJECTIVE: To evaluate the prognosis and complications of expectant therapy and curettage for retained product of conception (RPOC) after second trimester termination of pregnancy (TOP). METHODS: A total of 270 patients with RPOC following second trimester TOP in Nanfang Hospital between January, 2014 and December, 2015 were included in this study. The duration of vaginal bleeding time and menstruation recovery interval were compared between patients receiving expectant therapy and curettage for RPOC, and binary logistic regression was used to assess the risk factors for complications in bivariate and multivariate analyses...
May 20, 2017: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/28462399/can-letrozole-plus-hmg-protocol-improve-pregnancy-outcomes-in-frozen-thawed-embryo-transfer-an-rct
#19
Ashraf Aleyasin, Marzieh Aghahosseini, Leili Safdarian, Maryam Noorzadeh, Parvin Fallahi, Zahra Rezaeian, Sedighe Hoseinimosa
BACKGROUND: There are different methods in endometrial preparation for frozen-thawed embryo transfer (FET). OBJECTIVE: The purpose of this study was to compare the live birth rate in the artificial FET protocol (estradiol/ progesterone with GnRH-agonist) with stimulated cycle FET protocol (letrozole plus HMG). MATERIALS AND METHODS: This randomized clinical trial included 100 women (18-42 years) randomly assigned to two groups based on Bernoulli distribution...
February 2017: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/28461878/clinical-audit-of-ectopic-pregnancy
#20
Alaa Aldin Abdel Hamid, Almraghy Yousry, Safwat Abd El Radi, Omar Mamdouh Shabaan, Elzahry Mazen, Halal Nabil
OBJECTIVE: The aim of this study was to determine the risk factors of ectopic pregnancy in cases presented to the Woman's Health Hospital (WHH) in Assuit University, and to perform clinical audit on strategies for management of ectopic pregnancy in the WHH. METHODS: This descriptive hospital based study was conducted at the Woman's Health Hospital (WHH) of Assuit University (Egypt). There were 210 patients who were admitted to the WHH with the diagnosis of ectopic pregnancy in the period between February 1, 2015 through the end of October 2015...
March 2017: Electronic Physician
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