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Honey AND analgesia

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https://www.readbyqxmd.com/read/25256702/identifying-behavioural-differences-in-working-donkeys-in-response-to-analgesic-administration
#1
RANDOMIZED CONTROLLED TRIAL
F H Regan, J Hockenhull, J C Pritchard, A E Waterman-Pearson, H R Whay
REASONS FOR PERFORMING STUDY: To identify pain-related behaviour in working donkeys in order to assist their owners and veterinarians to recognise and manage pain. OBJECTIVES: To identify general and specific behaviours associated with pain or its relief using a trial with the nonsteroidal anti-inflammatory drug meloxicam (Metacam). STUDY DESIGN: Observer-blinded, placebo-controlled trial. METHODS: Forty adult male working donkeys with common clinical abnormalities were randomly assigned to receive either a single loading dose of meloxicam (1...
January 2016: Equine Veterinary Journal
https://www.readbyqxmd.com/read/24988309/ethanol-induced-effects-on-sting-extension-response-and-punishment-learning-in-the-western-honey-bee-apis-mellifera
#2
Manuel A Giannoni-Guzmán, Tugrul Giray, Jose Luis Agosto-Rivera, Blake K Stevison, Brett Freeman, Paige Ricci, Erika A Brown, Charles I Abramson
Acute ethanol administration is associated with sedation and analgesia as well as behavioral disinhibition and memory loss but the mechanisms underlying these effects remain to be elucidated. During the past decade, insects have emerged as important model systems to understand the neural and genetic bases of alcohol effects. However, novel assays to assess ethanol's effects on complex behaviors in social or isolated contexts are necessary. Here we used the honey bee as an especially relevant model system since bees are typically exposed to ethanol in nature when collecting standing nectar crop of flowers, and there is recent evidence for independent biological significance of this exposure for social behavior...
2014: PloS One
https://www.readbyqxmd.com/read/23584354/analgesic-effects-of-mad-honey-grayanotoxin-in-mice-models-of-acute-pain-and-painful-diabetic-neuropathy
#3
A Gunduz, I Eraydin, S Turkmen, O F Kalkan, S Turedi, U Eryigit, A Ayar
OBJECTIVES: The aim of this experimental study was to investigate the effects of mad honey (grayanotoxin, GTX), used in complementary medicine for a variety of purposes besides being food, on pain thresholds in normal mice as model for acute pain and diabetic mouse as model for neuropathic pain. METHODS: Hind paw withdrawal pain threshold to thermal stimulus was measured with a plantar analgesia meter in a mice model using healthy intact animals for acute pain and streptozotocin-induced diabetic animals for chronic neuropathic pain...
February 2014: Human & Experimental Toxicology
https://www.readbyqxmd.com/read/23445266/a-randomized-double-blinded-placebo-controlled-trial-of-intercostal-nerve-block-after-percutaneous-nephrolithotomy
#4
RANDOMIZED CONTROLLED TRIAL
R John D'A Honey, Daniela Ghiculete, A Andrew Ray, Kenneth T Pace
BACKGROUND AND PURPOSE: The optimal method of pain control after percutaneous nephrolithotomy (PCNL) remains controversial. We sought to determine whether intercostal nerve block with bupivicaine provided superior pain control, when compared with placebo, with a lower need for narcotics and improved health-related quality of life (HRQL) in the immediate postoperative period. PATIENTS AND METHODS: Sixty-three patients were randomized to receive intercostal blockade with either 20 mL of 0...
April 2013: Journal of Endourology
https://www.readbyqxmd.com/read/17943748/interventions-for-preventing-oral-mucositis-for-patients-with-cancer-receiving-treatment
#5
REVIEW
H V Worthington, J E Clarkson, O B Eden
BACKGROUND: Treatment of cancer is increasingly more effective but is associated with short and long term side effects. Oral side effects remain a major source of illness despite the use of a variety of agents to prevent them. One of these side effects is oral mucositis (mouth ulcers). OBJECTIVES: To evaluate the effectiveness of prophylactic agents for oral mucositis in patients with cancer receiving treatment, compared with other potentially active interventions, placebo or no treatment...
2007: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/17379239/flight-and-fight-a-comparative-view-of-the-neurophysiology-and-genetics-of-honey-bee-defensive-behavior
#6
REVIEW
G J Hunt
Honey bee nest defense involves guard bees that specialize in olfaction-based nestmate recognition and alarm-pheromone-mediated recruitment of nestmates to sting. Stinging is influenced by visual, tactile and olfactory stimuli. Both quantitative trait locus (QTL) mapping and behavioral studies point to guarding behavior as a key factor in colony stinging response. Results of reciprocal F1 crosses show that paternally inherited genes have a greater influence on colony stinging response than maternally inherited genes...
May 2007: Journal of Insect Physiology
https://www.readbyqxmd.com/read/16935736/comparison-of-bacteriostatic-normal-saline-and-lidocaine-used-as-intradermal-anesthesia-for-the-placement-of-intravenous-lines
#7
RANDOMIZED CONTROLLED TRIAL
Pamela E Windle, Meggie L Kwan, Honey Warwick, Agnes Sibayan, Charito Espiritu, Jennifer Vergara
Pain with intravenous (IV) insertion is a common fear for preoperative patients. As perianesthesia nurses, we take the necessary measures to minimize the discomfort and anxiety of our patients. Several research studies have found the use of bacteriostatic normal saline (BNS) to produce a less painful, yet equally effective, safer, and less expensive alternative method for intradermal anesthesia. The purpose of this study was to determine whether a difference existed in pain with intradermal injection and pain with venipuncture when intradermal anesthesia was used...
August 2006: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
https://www.readbyqxmd.com/read/16625538/interventions-for-preventing-oral-mucositis-for-patients-with-cancer-receiving-treatment
#8
REVIEW
H V Worthington, J E Clarkson, O B Eden
BACKGROUND: Treatment of cancer is increasingly more effective but is associated with short and long-term side effects. Oral side effects remain a major source of illness despite the use of a variety of agents to prevent them. One of these side effects is oral mucositis (mouth ulcers). OBJECTIVES: To evaluate the effectiveness of prophylactic agents for oral mucositis in patients with cancer receiving treatment, compared with other potentially active interventions, placebo or no treatment...
2006: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/14746959/manual-vacuum-aspiration-mva-in-the-management-of-first-trimester-pregnancy-loss
#9
COMPARATIVE STUDY
Rafet Gazvani, Emma Honey, Fiona M MacLennan, Allan Templeton
BACKGROUND: Manual vacuum aspiration is not widely used for the evacuation of retained products of conception in western Europe despite its well-proven success and safety record. Nor is there much information about its use under intravenous (systemic) analgesia or patient-controlled anaesthesia in modern settings. AIM: To evaluate the use of manual vacuum aspiration for the evacuation of retained products of conception under systemic analgesia or patient-controlled anaesthesia in the management of first trimester miscarriages...
February 10, 2004: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/11682403/a-comparison-of-patient-controlled-sedation-using-either-remifentanil-or-remifentanil-propofol-for-shock-wave-lithotripsy
#10
RANDOMIZED CONTROLLED TRIAL
H S Joo, W J Perks, M T Kataoka, L Errett, K Pace, R J Honey
UNLABELLED: Patient-controlled sedation (PCS) has been used for extracorporeal shock wave lithotripsy (SWL) because it allows for rapid individualized titration of anesthetics. Because of its sedating effects, the addition of propofol to remifentanil may improve patient tolerance of SWL with PCS. One hundred twenty patients were randomly assigned to receive remifentanil 10 microg or remifentanil 10 microg plus propofol 5 mg for PCS with zero-lockout interval. Nine patients in the Remifentanil group and three patients in the Remifentanil-Propofol group required additional sedatives to complete their SWL (P = 0...
November 2001: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/8880850/the-bee-venom-test-a-new-tonic-pain-test
#11
W R Lariviere, R Melzack
The present study describes a new test of tonic pain to be used as an animal model of persistent pain. First, pain responses and edema produced by subcutaneous injection of increasing doses of honey bee venom into the hind paw of the rat were quantified. Second, the effect of morphine and aspirin on the pain responses was investigated. Finally, the response to concurrent injections of bee venom and formalin was examined. Subcutaneous injection of bee venom produced local inflammation, tonic-pain responses lasting from 10 min to more than 1 h, and marked edema lasting from 3 h to more than 48 h...
August 1996: Pain
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