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https://www.readbyqxmd.com/read/28533985/metabarcoding-monitoring-analysis-the-pros-and-cons-of-using-co-extracted-environmental-dna-and-rna-data-to-assess-offshore-oil-production-impacts-on-benthic-communities
#1
Olivier Laroche, Susanna A Wood, Louis A Tremblay, Gavin Lear, Joanne I Ellis, Xavier Pochon
Sequencing environmental DNA (eDNA) is increasingly being used as an alternative to traditional morphological-based identification to characterize biological assemblages and monitor anthropogenic impacts in marine environments. Most studies only assess eDNA which, compared to eRNA, can persist longer in the environment after cell death. Therefore, eRNA may provide a more immediate census of the environment due to its relatively weaker stability, leading some researchers to advocate for the use of eRNA as an additional, or perhaps superior proxy for portraying ecological changes...
2017: PeerJ
https://www.readbyqxmd.com/read/28532604/validation-of-dwi-pre-processing-procedures-for-reliable-differentiation-between-human-brain-gliomas
#2
Sebastian Vellmer, Aram S Tonoyan, Dieter Suter, Igor N Pronin, Ivan I Maximov
Diffusion magnetic resonance imaging (dMRI) is a powerful tool in clinical applications, in particular, in oncology screening. dMRI demonstrated its benefit and efficiency in the localisation and detection of different types of human brain tumours. Clinical dMRI data suffer from multiple artefacts such as motion and eddy-current distortions, contamination by noise, outliers etc. In order to increase the image quality of the derived diffusion scalar metrics and the accuracy of the subsequent data analysis, various pre-processing approaches are actively developed and used...
May 19, 2017: Zeitschrift Für Medizinische Physik
https://www.readbyqxmd.com/read/28529758/noise-aware-dictionary-learning-based-sparse-representation-framework-for-detection-and-removal-of-single-and-combined-noises-from-ecg-signal
#3
Udit Satija, Barathram Ramkumar, M Sabarimalai Manikandan
Automatic electrocardiogram (ECG) signal enhancement has become a crucial pre-processing step in most ECG signal analysis applications. In this Letter, the authors propose an automated noise-aware dictionary learning-based generalised ECG signal enhancement framework which can automatically learn the dictionaries based on the ECG noise type for effective representation of ECG signal and noises, and can reduce the computational load of sparse representation-based ECG enhancement system. The proposed framework consists of noise detection and identification, noise-aware dictionary learning, sparse signal decomposition and reconstruction...
February 2017: Healthcare Technology Letters
https://www.readbyqxmd.com/read/28526950/the-effect-of-post-mortem-computed-tomography-angiography-pmcta-using-water-soluble-iodine-based-radiographic-contrast-on-histological-analysis-of-the-liver-kidneys-and-left-ventricle-of-the-heart
#4
Samantha Higgins, Sarah Parsons, Noel Woodford, Matthew Lynch, Christopher Briggs, Chris O'Donnell
The purpose of this study was to investigate the impact of post-mortem computed-tomography angiography (PMCTA) on the histology of the liver, kidneys and heart. Multiple tissue cores were collected from the liver, left and right kidneys and left ventricle utilizing CT-guided biopsy. Subsequent whole body PMCTA was performed using a solution of polyethylene glycol and iodinated radiographic contrast, and an embalming pump. Corresponding biopsy cores were collected at autopsy, and blinded histology analysis assessing for PMCTA-induced histology artefact was performed...
May 20, 2017: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/28522072/cardiovascular-magnetic-resonance-in-systemic-sclerosis-pearls-and-pitfalls
#5
REVIEW
Sophie I Mavrogeni, Juerg Schwitter, Luna Gargani, Alessia Pepe, Lorenzo Monti, Yannick Allanore, Marco Matucci-Cerinic
Systemic sclerosis (SSc) is an autoimmune disease characterized by vascular dysfunction and excessive fibrosis, involving internal organs including the heart. The estimated prevalence of cardiac involvement in SSc is high and remains subclinical until the late stages. It is either primary, related to myocardial inflammation and fibrosis, or secondary, due to pulmonary arterial hypertension (SSc-PAH) or systemic hypertension, in those patients with renal involvement. Cardiovascular magnetic resonance (CMR) is a useful tool for the early assessment of cardiac involvement in SSc...
March 31, 2017: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/28512747/visuoperceptual-processing-in-children-with-neurofibromatosis-type-1-true-deficit-or-artefact
#6
Lien Van Eylen, Ellen Plasschaert, Johan Wagemans, Bart Boets, Eric Legius, Jean Steyaert, Ilse Noens
Impairments in visuoperceptual processing have long been considered a hallmark deficit of individuals with Neurofibromatosis type 1 (NF1). However, it is unclear which specific visuoperceptual subprocesses are impaired and whether impairments on these tasks really result from visuoperceptual impairments or rather from confounding factors like Executive Functioning (EF) impairments, lower intelligence (IQ) and/or co-occurring symptoms of Autism Spectrum Disorder (ASD). To answer these questions, we administered four visuoperceptual tasks and two control tasks in 39 children with NF1, 52 typically developing children and 52 children with ASD (8-18 years), all matched for age and gender...
June 2017: American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics
https://www.readbyqxmd.com/read/28509869/experimental-approach-for-the-uncertainty-assessment-of-3d-complex-geometry-dimensional-measurements-using-computed-tomography-at-the-mm-and-sub-mm-scales
#7
Roberto Jiménez, Marta Torralba, José A Yagüe-Fabra, Sinué Ontiveros, Guido Tosello
The dimensional verification of miniaturized components with 3D complex geometries is particularly challenging. Computed Tomography (CT) can represent a suitable alternative solution to micro metrology tools based on optical and tactile techniques. However, the establishment of CT systems' traceability when measuring 3D complex geometries is still an open issue. In this work, an alternative method for the measurement uncertainty assessment of 3D complex geometries by using CT is presented. The method is based on the micro-CT system Maximum Permissible Error (MPE) estimation, determined experimentally by using several calibrated reference artefacts...
May 16, 2017: Sensors
https://www.readbyqxmd.com/read/28507709/first-total-synthesis-of-concavine
#8
François Saint-Dizier, Nigel S Simpkins
The synthesis of the unusual alkaloid concavine, isolated from Clitocybe concava (Basidiomycetae), has been accomplished. The synthetic route features regio- and stereoselective manipulation of polycyclic imide intermediates via enolate substitution and Grignard addition, along with a key bridge-forming step involving a new method for sulfenylative radical cyclisation. The NMR data for synthetic concavine demonstrate that the original data reported for the natural product refer to the derived acetic acid salt, probably formed as an artefact of isolation or purification...
May 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/28505625/metal-artifact-reduction-on-chest-computed-tomography-examinations-comparison-of-the-iterative-metallic-artefact-reduction-algorithm-and-the-monoenergetic-approach
#9
Julien Pagniez, Louise Legrand, Suonita Khung, Jean-Baptiste Faivre, Alain Duhamel, Andreas Krauss, Jacques Remy, Martine Remy-Jardin
OBJECTIVE: The aim of the study was to compare iterative metallic artefact reduction (iMAR) and monochromatic imaging on metal artifact reduction. MATERIALS AND METHODS: Follow-up of 29 occluded pulmonary arteriovenous malformations was obtained with dual-energy computed tomography with reconstruction of averaged images using filtered back projection (group 1), iMAR (group 2), and creation of high-energy monoenergetic images (group 3). Two types of coils had been used: (a) nickel only (group A, n = 18) and (b) nickel and platinum (group B, n = 11)...
May 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28503888/cryoglobulinaemic-glomerulonephritis-artefacts-associated-with-laboratory-diagnosis-and-need-for-renal-biopsy
#10
Ajish Radhamma, Jobert Anjelo, Tony J Elias
Cryoglobulinemia as a cause of renal impairment is uncommon but needs to be considered in viral hepatitis and haematological malignancies. Often detection and estimation of cryoglobulins are confounded by collection and processing errors. This report highlights the need for stringent processing measures if the clinical suspicion is high.
May 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/28484806/chemical-characterisation-of-the-whole-plant-cell-wall-of-archaeological-wood-an-integrated-approach
#11
Luca Zoia, Diego Tamburini, Marco Orlandi, Jeannette Jacqueline Łucejko, Anika Salanti, Eeva-Liisa Tolppa, Francesca Modugno, Maria Perla Colombini
Wood artefacts undergo complex alteration and degradation during ageing, and gaining information on the chemical composition of wood in archaeological artefacts is fundamental to plan conservation strategies. In this work, an integrated analytical approach based on innovative NMR spectroscopy procedures, gel permeation chromatography and analytical pyrolysis coupled with gas chromatography/mass spectrometry (Py-GC-MS) was applied for the first time on archaeological wood from the Oseberg collection (Norway), in order to evaluate the chemical state of preservation of the wood components, without separating them...
May 8, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28484325/element-analysis-a-wavelet-based-method-for-analysing-time-localized-events-in-noisy-time-series
#12
Jonathan M Lilly
A method is derived for the quantitative analysis of signals that are composed of superpositions of isolated, time-localized 'events'. Here, these events are taken to be well represented as rescaled and phase-rotated versions of generalized Morse wavelets, a broad family of continuous analytic functions. Analysing a signal composed of replicates of such a function using another Morse wavelet allows one to directly estimate the properties of events from the values of the wavelet transform at its own maxima. The distribution of events in general power-law noise is determined in order to establish significance based on an expected false detection rate...
April 2017: Proceedings. Mathematical, Physical, and Engineering Sciences
https://www.readbyqxmd.com/read/28482772/positive-emotion-in-knowledge-creation
#13
Michael Hodgins, Ann Dadich
Purpose Despite the importance of evidence-based practice, the translation of knowledge into quality healthcare continues to be stymied by an array of micro, meso and macro factors. The purpose of this paper is to suggest a need to consider different - if not unconventional approaches - like the role of positive emotion, and how it might be used to promote and sustain knowledge translation (KT). Design/methodology/approach By reviewing and coalescing two distinct theories - the broaden-and-build theory of positive emotions and the organisational knowledge creation theory - this paper presents a case for the role of positive emotion in KT...
April 10, 2017: Journal of Health Organization and Management
https://www.readbyqxmd.com/read/28480136/the-earliest-known-titanosauriform-sauropod-dinosaur-and-the-evolution-of-brachiosauridae
#14
Philip D Mannion, Ronan Allain, Olivier Moine
Brachiosauridae is a clade of titanosauriform sauropod dinosaurs that includes the well-known Late Jurassic taxa Brachiosaurus and Giraffatitan. However, there is disagreement over the brachiosaurid affinities of most other taxa, and little consensus regarding the clade's composition or inter-relationships. An unnamed partial sauropod skeleton was collected from middle-late Oxfordian (early Late Jurassic) deposits in Damparis, in the Jura department of eastern France, in 1934. Since its brief description in 1943, this specimen has been informally known in the literature as the 'Damparis sauropod' and 'French Bothriospondylus', and has been considered a brachiosaurid by most authors...
2017: PeerJ
https://www.readbyqxmd.com/read/28479539/trust-essential-requirement-and-basis-for-phealth-services
#15
Pekka Ruotsalainen, Bernd Blobel
Trust is a social code and glue between persons and organizations in any business domain including health. pHealth is a complex concept that is built around health service providers, individuals and artefacts such as sensors, mobile devices, networks, computers, and software applications. It has many stakeholders such as organizations, persons, patients, customers, and tele-operators. pHealth services are increasingly offered in insecure information space, and used over organizational, geographical and jurisdictional borders...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28476973/excluded-volume-effects-in-on-and-off-lattice-reaction-diffusion-models
#16
Lina Meinecke, Markus Eriksson
Mathematical models are important tools to study the excluded volume effects on reaction-diffusion systems, which are known to play an important role inside living cells. Detailed microscopic simulations with off-lattice Brownian dynamics become computationally expensive in crowded environments. In this study, the authors therefore investigate to which extent on-lattice approximations, the so-called cellular automata models, can be used to simulate reactions and diffusion in the presence of crowding molecules...
April 2017: IET Systems Biology
https://www.readbyqxmd.com/read/28476505/coronary-computed-tomography-angiography-derived-risk-score-in-predicting-cardiac-events
#17
Valtteri Uusitalo, Vasileios Kamperidis, Michiel A de Graaf, Teemu Maaniitty, Iida Stenström, Alexander Broersen, Jouke Dijkstra, Arthur J Scholte, Antti Saraste, Jeroen J Bax, Juhani Knuuti
BACKGROUND: We evaluated the prognostic value of an integrated atherosclerosis risk score combining the markers of coronary plaque burden, location and composition as assessed by computed tomography angiography (CTA). METHODS: 922 consecutive patients underwent CTA for suspected coronary artery disease (CAD). Patients without atherosclerosis (n = 261) and in whom quantitative CTA analysis was not feasible due to image quality, step-artefacts or technical factors related to image acquisition or data storage (n = 153) were excluded...
April 27, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28476243/advanced-dual-energy-ct-applications-for-the-evaluation-of-the-soft-tissues-of-the-neck
#18
REVIEW
R Forghani, S K Mukherji
There are multiple emerging advanced computed tomography (CT) applications for the evaluation of the neck, many based on dual-energy CT (DECT). DECT is an advanced form of CT in which scan acquisition is performed at two different energies, enabling spectral tissue characterisation beyond what is possible with conventional single-energy CT and potentially providing a new horizon for quantitative analysis and tissue characterisation, particularly in oncological imaging. The purpose of this review is to familiarise the reader with DECT principles and review different clinical applications for the evaluation of the soft tissues of the neck...
May 2, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28475490/reducing-4dcbct-imaging-time-and-dose-the-first-implementation-of-variable-gantry-speed-4dcbct-on-a-linear-accelerator
#19
Ricky T O'Brien, Uros Stankovic, Jan-Jakob Sonke, Paul J Keall
Four dimensional cone beam computed tomography (4DCBCT) uses a constant gantry speed and imaging frequency that are independent of the patient's breathing rate. Using a technique called respiratory motion guided 4DCBCT (RMG-4DCBCT), we have previously demonstrated that by varying the gantry speed and imaging frequency, in response to changes in the patient's real-time respiratory signal, the imaging dose can be reduced by 50-70%. RMG-4DCBCT optimally computes a patient specific gantry trajectory to eliminate streaking artefacts and projection clustering that is inherent in 4DCBCT imaging...
May 5, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28470763/membrane-protein-stoichiometry-studied-in-intact-mammalian-cells-using-liquid-phase-electron-microscopy
#20
N DE Jonge
Receptor membrane proteins in the plasma membranes of cells respond to extracellular chemical signals by conformational changes, spatial redistribution, and (re-)assembly into protein complexes, for example, into homodimers (pairs of the same protein type). The functional state of the proteins can be determined from information about how subunits are assembled into protein complexes. Stoichiometric information about the protein complex subunits, however, is generally not obtained from intact cells but from pooled material extracted from many cells, resulting in a lack of fundamental knowledge about the functioning of membrane proteins...
May 4, 2017: Journal of Microscopy
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