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psychiatric disorders in breast cancer patients

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https://www.readbyqxmd.com/read/29133983/concomitant-psychiatric-symptoms-and-impaired-quality-of-life-in-women-with-cervical-cancer-a-critical-review
#1
REVIEW
Stephanie Klügel, Caroline Lücke, Aurora Meta, Meike Schild-Suhren, Eduard Malik, Alexandra Philipsen, Helge Ho Müller
Our aim was to summarize the current relevant literature on concomitant psychiatric symptoms with a focus on anxiety/depression in a population with gynecologic cancer; to identify the predictors, associated factors, and prevention strategies of psychiatric disorders; to examine psychiatric disorders in a population with recurrent gynecologic cancer; and to describe the limitations of the literature and future research areas. Little is known about attending psychiatric disorders in patients with gynecologic and other malignant diseases like cervical or breast cancer...
2017: International Journal of Women's Health
https://www.readbyqxmd.com/read/29042887/the-prevalence-of-depression-among-patients-with-the-top-ten-most-common-cancers-in-south-korea
#2
Boram Park, Soyoung Youn, Ki-Kyung Yi, Su-Yeon Lee, Jung-Sun Lee, Seockhoon Chung
OBJECTIVE: Among the various psychiatric disorders, depression is a common comorbid condition in cancer patients. Due to the distinct and diverse nature of cancer, the prevalence of depression may be assumed to be affected by differences in primary cancer sites. In this study, we explored the prevalence rates of depression among the ten most prevalent cancers in South Korea using a national patient sample. METHODS: This was a 1-year cross-sectional study using a national patient sample provided by the South Korean National Health Insurance in 2011...
September 2017: Psychiatry Investigation
https://www.readbyqxmd.com/read/28979126/depression-and-family-support-in-breast-cancer-patients
#3
Jian-An Su, Dah-Cherng Yeh, Ching-Chi Chang, Tzu-Chin Lin, Ching-Hsiang Lai, Pei-Yun Hu, Yi-Feng Ho, Vincent Chin-Hung Chen, Tsu-Nai Wang, Michael Gossop
BACKGROUND: Breast cancer is the most common cancer in women. Among the survivors, depression is one of the most common psychiatric comorbidities. This paper reports the point prevalence of major depressive disorder among breast cancer patients and the association between family support and major depressive disorder. METHODS: Clinical data were collected from a breast cancer clinic of a general hospital in central Taiwan. Participants included 300 patients who were older than 18 years and diagnosed with breast cancer...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28856543/risk-of-depression-anxiety-and-adjustment-disorders-in-women-with-a-suspected-but-unconfirmed-diagnosis-of-breast-or-genital-organ-cancer-in-germany
#4
Karel Kostev, Louis Jacob, Matthias Kalder
BACKGROUND: Breast cancer (BC) and genital organ cancers (GOC) are known to have a major impact on the quality of life of patients. The aim of this study was to analyze the risk of depression, anxiety, and adjustment disorders in women in Germany with a suspected but unconfirmed diagnosis of BC or GOC in their medical history. METHODS: This study included women who received a suspected diagnosis of BC or GOC and were followed between 2007 and 2015 (index date). These women were matched (1:1:1) by age to women with a confirmed diagnosis of BC or GOC and women without a cancer diagnosis...
October 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/28807009/adverse-mental-health-outcomes-in-breast-cancer-survivors-compared-to-women-who-did-not-have-cancer-systematic-review-protocol
#5
Helena Carreira, Rachael Williams, Martin Müller, Rhea Harewood, Krishnan Bhaskaran
BACKGROUND: Recent increasing trends in breast cancer incidence and survival have resulted in unprecedented numbers of cancer survivors in the general population. A cancer diagnosis may have a profound psychological impact, and breast cancer treatments often cause long-term physical sequelae, potentially affecting women's mental health. The aim of this systematic review is to identify and summarise all studies that have compared mental health outcomes in breast cancer survivors, versus women who did not have cancer...
August 14, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/28789594/the-impact-of-prior-psychiatric-medical-treatment-on-return-to-work-after-a-diagnosis-of-breast-cancer-a-registry-based-study
#6
Laura Schärfe Jensen, Charlotte Overgaard, Jens Peter Garne, Henrik Bøggild, Kirsten Fonager
PURPOSE: Breast cancer and psychiatric disorders negatively impact work life, both positively associated with unemployment and early retirement. Our purpose was to assess whether being prescribed psychiatric medication, 2-4 yrs prior to a diagnosis of breast cancer, could impact the likelihood of returning to work after cancer therapy. METHODS: 16,868 self-supporting women, diagnosed with breast cancer in Denmark from 2000 to 2012, were identified from a population-based clinical database, then cross-referenced to data held for psychiatric medication usage, sociodemographics, and labour-market participation...
August 1, 2017: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/28331743/psychiatric-symptoms-and-psychosocial-problems-in-patients-with-breast-cancer
#7
REVIEW
Filiz İzci, Ahmet Serkan İlgün, Ebru Fındıklı, Vahit Özmen
Cancer is a physical disease and also one of the leading clinical manifestations where psychosocial problems are prevalent. Psychosocial problems that these patients may have in the long run include anxiety, uneasiness, mourning, helplessness, fatigue, impairment of concentration, sleep disorders, mental and cognitive reservation, sexual dysfunction, infertility, psychological distress, and psychiatric disorders. Psychosocial problems have a nature of underpinning the emergence of psychological troubles. The prevalence of psychological disorders in patients with cancer range from 29% to 47%...
July 2016: Journal of Breast Health (2013)
https://www.readbyqxmd.com/read/28323373/the-impact-of-mental-illness-on-uptake-of-genetic-counseling-for-hereditary-breast-cancer-and-ovarian-cancer-in-a-multiethnic-cohort-of-breast-cancer-patients
#8
Marra G Ackerman, Peter A Shapiro, Austin Coe, Meghna S Trivedi, Katherine D Crew
We evaluated whether mental illness is a barrier to genetic counseling for hereditary breast and ovarian cancer (HBOC) in multiethnic breast cancer patients. We conducted a retrospective analysis of 308 women with newly diagnosed breast cancer and eligible for HBOC genetic testing seen in the breast clinic of an academic, urban medical center from 2007 to 2015. Uptake of genetic services and history of mental health disorder (MHD), defined as a psychiatric diagnosis or treatment with an antidepressant, mood stabilizer, anxiolytic, or antipsychotic medication, were ascertained by medical chart review...
September 2017: Breast Journal
https://www.readbyqxmd.com/read/28235749/analysis-of-patient-narratives-in-disease-blogs-on-the-internet-an-exploratory-study-of-social-pharmacovigilance
#9
Shinichi Matsuda, Kotonari Aoki, Shiho Tomizawa, Masayoshi Sone, Riwa Tanaka, Hiroshi Kuriki, Yoichiro Takahashi
BACKGROUND: Although several reports have suggested that patient-generated data from Internet sources could be used to improve drug safety and pharmacovigilance, few studies have identified such data sources in Japan. We introduce a unique Japanese data source: tōbyōki, which translates literally as "an account of a struggle with disease." OBJECTIVE: The objective of this study was to evaluate the basic characteristics of the TOBYO database, a collection of tōbyōki blogs on the Internet, and discuss potential applications for pharmacovigilance...
February 24, 2017: JMIR Public Health and Surveillance
https://www.readbyqxmd.com/read/28123722/systematic-analysis-of-the-achaete-scute-complex-like-gene-signature-in-clinical-cancer-patients
#10
Chih-Yang Wang, Payam Shahi, John Ting Wei Huang, Nam Nhut Phan, Zhengda Sun, Yen-Chang Lin, Ming-Derg Lai, Zena Werb
The achaete-scute complex-like (ASCL) family, also referred to as 'achaete-scute complex homolog' or 'achaete-scute family basic helix-loop-helix transcription factor', is critical for proper development of the nervous system and deregulation of ASCL plays a key role in psychiatric and neurological disorders. The ASCL family consists of five members, namely ASCL1, ASCL2, ASCL3, ASCL4 and ASCL5. The ASCL1 gene serves as a potential oncogene during lung cancer development. There is a correlation between increased ASCL2 expression and colon cancer development...
January 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28062982/psychiatric-comorbidities-among-breast-cancer-survivors-in-south-korea-a-nationwide-population-based-study
#11
Jaesung Heo, Mison Chun, Young-Taek Oh, O Kyu Noh, Logyoung Kim
PURPOSE: The aim of this study was to analyze the prevalence of mental disorders in breast cancer survivors using claims data from the Health Insurance Review and Assessment Service in South Korea. We also analyzed patterns of mental disorders with respect to the time of diagnosis and age. MATERIALS AND METHODS: We confirmed mental disorders in a nationwide cohort of 87,843 people who were diagnosed with invasive breast cancer and underwent surgery between January 1, 2010 and December 31, 2014...
February 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/27817040/female-infertility-infertility-associated-diagnoses-and-comorbidities-a-review
#12
REVIEW
Brent Hanson, Erica Johnstone, Jessie Dorais, Bob Silver, C Matthew Peterson, James Hotaling
PURPOSE: The purpose of the study is to evaluate existing literature for possible associations between female infertility, infertility-associated diagnoses, and the following areas of disease: psychiatric disorders, breast cancer, ovarian cancer, endometrial cancer, cardiovascular disease, and metabolic dysfunction. METHODS: The design of the study is a literature review. The patients were women included in 26 selected studies due to a diagnosis of infertility or a reproductive disorder associated with infertility...
February 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/27346419/breast-leptomeningeal-metastasis-recurrence-presenting-as-a-manic-episode
#13
Michel Reich, Edwina Girard, Emilie Le Rhun
OBJECTIVE: Leptomeningeal metastasis (LM) is a neurooncological complication of advanced cancer that has a poor prognosis. The incidence of LM is increasing due to advances in neuroimaging. At the same time, the development of new systemic treatments with poor central nervous system penetration has improved outcomes and survival. However, diagnosis of LM remains quite difficult due to clinical polymorphism, inconsistent imaging abnormalities, and the inconsistent presence of neoplastic cells in cerebrospinal fluid...
April 2017: Palliative & Supportive Care
https://www.readbyqxmd.com/read/27303726/drug-repurposing-screening-identifies-novel-compounds-that-effectively-inhibit-toxoplasma-gondii-growth
#14
Ashley J Dittmar, Allison A Drozda, Ira J Blader
The urgent need to develop new antimicrobial therapies has spawned the development of repurposing screens in which well-studied drugs and other types of compounds are tested for potential off-label uses. As a proof-of-principle screen to identify compounds effective against Toxoplasma gondii, we screened a collection of 1,120 compounds for the ability to significantly reduce Toxoplasma replication. A total of 94 compounds blocked parasite replication with 50% inhibitory concentrations of <5 µM. A significant number of these compounds are established inhibitors of dopamine or estrogen signaling...
March 2016: MSphere
https://www.readbyqxmd.com/read/27152880/tamoxifen-in-men-a-review-of-adverse-events
#15
REVIEW
E Wibowo, P A Pollock, N Hollis, R J Wassersug
Tamoxifen is an off-label option to treat men for breast cancer, infertility, and idiopathic gynecomastia. Lately, tamoxifen has been proposed as a treatment to prevent gynecomastia in prostate cancer patients receiving antiandrogen therapy. We reviewed the adverse events (AEs) reported in studies of men prescribed tamoxifen for these conditions to better understand its side-effect profile. We searched PubMed for randomized controlled trials (RCTs) that included safety data of tamoxifen treatment in men with prostate cancer, breast cancer, infertility, and idiopathic gynecomastia...
September 2016: Andrology
https://www.readbyqxmd.com/read/26991377/acute-treatment-with-doxorubicin-induced-neurochemical-impairment-of-the-function-of-dopamine-system-in-rat-brain-structures
#16
Lucyna Antkiewicz-Michaluk, Krzysztof Krzemieniecki, Irena Romanska, Jerzy Michaluk, Anna Krygowska-Wajs
BACKGROUND: The clinical studies have shown that chemotherapy may impair cognitive functions especially in the patients treated for breast cancer. It should be mention that only few studies have made use of animals to investigate the effects of chemotherapy on the brain function. Doxorubicin (Adriamycin) is an anthracycline antibiotic commonly used for chemotherapy of breast cancer. METHODS: This study examined the effect of doxorubicin (1.5 and 3.0mg/kg ip) after acute administration on the levels of dopamine, noradrenaline, serotonin and their metabolites in the rat brain structures connected with cognition and psychiatric disorders...
June 2016: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/26935189/cancer-screening-among-peer-led-community-wellness-center-enrollees
#17
Lois E Rockson, Margaret A Swarbrick, Carlos Pratt
Growing evidence suggests health disparities exist in services for individuals with mental disorders served by the public mental health system. The current study assessed the use of cancer screening services among New Jersey residents in publicly funded mental health programs. Self-administered written surveys were completed by 148 adults using peer-led community wellness centers throughout New Jersey. Information was collected on (a) the use of breast, cervical, and colorectal cancer screening services; (b) barriers to receiving preventive services; and (c) perceptions of overall health...
March 2016: Journal of Psychosocial Nursing and Mental Health Services
https://www.readbyqxmd.com/read/26753454/efficasy-of-different-psychiatric-treatment-methods-of-liaison-psychiatrist-in-treatment-of-women-with-breast-cancer
#18
Sanda Anton, Damir Gugić, Križo Katinić, Jelena Topić
Being diagnosed with breast cancer is a traumatic event that can lead to development of different mental disorders and influences all aspects of affected woman's life. Anxiety and Depressive Disorders in physically ill people still don't have clear diagnostic criteria which make diagnosis and treatment very difficult since different psychiatric therapeutic approaches have different effects. The aim was to evaluate influence of separate and combined psychotherapeutic approach (psychodynamic and cognitive-behavioral) and psychopharmacotherapy on decrease of anxiety and depression in breast cancer patients...
June 2015: Collegium Antropologicum
https://www.readbyqxmd.com/read/26747215/personality-disorders-but-not-cancer-severity-or-treatment-type-are-risk-factors-for-later-generalised-anxiety-disorder-and-major-depressive-disorder-in-non-metastatic-breast-cancer-patients
#19
Anne-Laure Champagne, Paul Brunault, Grégoire Huguet, Isabelle Suzanne, Jean-Louis Senon, Gilles Body, Emmanuel Rusch, Guillaume Magnin, Mélanie Voyer, Christian Réveillère, Vincent Camus
This study aimed to determine whether personality disorders were associated with later Major Depressive Disorder (MDD) or Generalised Anxiety Disorder (GAD) in breast cancer patients. This longitudinal and multicentric study included 120 French non-metastatic breast cancer patients. After cancer diagnosis (T1) and 7 months after diagnosis (T3), we assessed MDD and GAD (Mini International Neuropsychiatric Interview 5.0). We assessed personality disorders 3 months after diagnosis (VKP). We used multiple logistic regression analysis to determine what were the factors associated with GAD and MDD at T3...
February 28, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/26558799/efficacy-of-fulvestrant-500-mg-in-japanese-postmenopausal-advanced-recurrent-breast-cancer-patients-and-factors-associated-with-prolonged-time-to-treatment-failure
#20
Kazuhiro Araki, Naoko Ishida, Rie Horii, Shunji Takahashi, Futoshi Akiyama, Yoshinori Ito, Shinji Ohno
OBJECTIVE: We aimed to confirm the efficacy of fulvestrant in Japanese postmenopausal advanced/recurrent breast cancer (ABC) patients, and investigate factors contributing to time-to-treatment failure (TTF) prolongation. RESEARCH DESIGN AND METHODS: This retrospective study included 194 ABC patients who received fulvestrant (500 mg) from January 2012 to December 2014. MAIN OUTCOME MEASURES: TTF (efficacy measure), overall survival (OS), factors prolonging TTF and adverse events were evaluated...
2015: Expert Opinion on Pharmacotherapy
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