Viktoriia Batarchuk, Yurii Shepelytskyi, Vira Grynko, Antal Halen Kovacs, Aaron Hodgson, Karla Rodriguez, Ruba Aldossary, Tanu Talwar, Carson Hasselbrink, Iulian C Ruset, Brenton DeBoef, Mitchell S Albert
Molecular magnetic resonance imaging (MRI) is an emerging field that is set to revolutionize our perspective of disease diagnosis, treatment efficacy monitoring, and precision medicine in full concordance with personalized medicine. A wide range of hyperpolarized (HP) 129 Xe biosensors have been recently developed, demonstrating their potential applications in molecular settings, and achieving notable success within in vitro studies. The favorable nuclear magnetic resonance properties of 129 Xe, coupled with its non-toxic nature, high solubility in biological tissues, and capacity to dissolve in blood and diffuse across membranes, highlight its superior role for applications in molecular MRI settings...
February 5, 2024: International Journal of Molecular Sciences