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Proximal hypospadias

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https://www.readbyqxmd.com/read/29717506/width-proportion-of-the-urethral-plate-to-the-glans-can-serve-as-an-appraisal-index-of-the-urethral-plate-in-hypospadias-repair
#1
Wei Ru, Jing Shen, Daxing Tang, Shan Xu, Dehua Wu, Chang Tao, Guangjie Chen, Lei Gao, Xiaohao Wang, Yiding Shen
OBJECTIVES: To find a new appropriate evaluation for urethral plate quality in hypospadias repair, with particular interest in the width proportion of the urethral plate to the glans, serving as an appraisal index. METHODS: Data were prospectively collected from prepubertal boys who underwent primary tubularized incised plate hypospadias repair between January 2014 and April 2016 in one center. Intrinsic parameters of the penis (meatal location, glans width, urethral plate width and curvature degree) were measured during the operation...
May 1, 2018: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/29642338/re-long-term-functional-outcomes-after-penoscrotal-hypospadias-repair-a-retrospective-comparative-study-of-proximal-tip-onlay-and-duckett
#2
Douglas A Canning
No abstract text is available yet for this article.
April 2018: Journal of Urology
https://www.readbyqxmd.com/read/29624839/proximal-hypospadias-treated-with-a-transverse-preputial-island-tube-long-term-functional-sexual-and-cosmetic-outcomes
#3
S P Rynja, T P V M de Jong, J L H R Bosch, L M O de Kort
OBJECTIVE: To study long-term urinary and sexual function and cosmetic outcomes in adult hypospadias patients, who underwent a single-stage transverse preputial island tube (TPIT) in childhood. Long-term data on outcomes of proximal hypospadias patients with severe coexisting curvature and insufficient urethral plate are scarce, but are necessary to decide which repair technique is most beneficial. PATIENTS AND METHODS: Proximal hypospadias patients operated with TPIT were compared to distal hypospadias (DH) patients and to a control group of male medical students...
April 6, 2018: BJU International
https://www.readbyqxmd.com/read/29610178/proximal-hypospadias-and-a-novel-wt1-variant-when-should-genetic-testing-be-considered
#4
Elizabeth Dabrowski, Amy E Armstrong, Elizabeth Leeth, Emilie Johnson, Earl Cheng, Yasmin Gosiengfiao, Courtney Finlayson
We present a case of an infant with proximal hypospadias, penoscrotal transposition, and bilaterally descended testes found to have a clinically significant WT1 gene alteration on a customized disorder of sex development genetic panel in which 62 genes associated with 46, XY disorders of sex development were evaluated. This diagnosis led to early screening for and diagnosis and treatment of Wilms tumor. Patients with proximal hypospadias are not routinely evaluated by genetic testing, and when initial hormonal analyses are within normal ranges for a typical male patient, the genital atypia is usually attributed to an isolated anatomic abnormality...
April 2018: Pediatrics
https://www.readbyqxmd.com/read/29511587/long-term-follow-up-of-proximal-hypospadias-repair-urethral-stricture-should-be-excluded-in-adults-who-present-with-epididymo-orchitis
#5
Kailas P Bhandarkar, Dinesh H Kittur, Santosh V Patil, Sudhakar S Jadhav
Objective: Epididymo-orchitis (EO) is a well-known complication of urinary tract infections (UTI) in children. This is commonly seen in children who had hypospadias repair or in those who had surgery for anorectal malformation especially when it results in urethral stricture. However EO occurring as a complication of urethral stricture in adults operated for hypospadias in childhood is not well documented in the literature. Material and methods: This is a retrospective review of four adults who had proximal hypospadias repair in childhood...
March 2018: Turkish Journal of Urology
https://www.readbyqxmd.com/read/29473028/results-of-onlay-preputial-flap-urethroplasty-for-the-single-stage-repair-of-mid-and-proximal-hypospadias
#6
Ricardo González, Anja Lingnau, Barbara Magda Ludwikowski
Aims: To report current results of preputial flap onlay urethroplasty using the principle of the total preputial flap (TPF) for the one-stage repair of mid- and proximal hypospadias. Methods: This study was a retrospective chart review of patients in a prospectively kept database of all hypospadias operations performed at two institutions from January 1 2011 to August 2017. Inclusion criteria: all patients who underwent hypospadias repair using a preputial only flap urethroplasty based on the principle of the TPF...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29332064/recurrent-intragenic-duplication-within-the-nr5a1-gene-and-severe-proximal-hypospadias
#7
Matthieu Peycelon, Lamisse Mansour-Hendili, Capucine Hyon, Nathalie Collot, Muriel Houang, Marie Legendre, Maud Chabaud, Marie-Dominique Bouvier, Georges Audry, Serge Amselem, Jean-Pierre Siffroi
A heterozygous intragenic duplication within the repeated area (CTGCAGCTG)×2 of the NR5A1 gene was found in a 15-year-old 46,XY DSD (disorders/differences of sex development) patient with micropenis and severe proximal hypospadias. This heterozygous duplication has already been described twice in boys with a similar phenotype, whereas a deletion of 3 amino acids at the same position in the protein SF-1 has been described in a 46,XX patient with primary ovarian failure and short stature. These data suggest that this region within the NR5A1 gene has an important role for SF-1 protein function in gonads and is a hotspot for intragenic rearrangements...
2017: Sexual Development: Genetics, Molecular Biology, Evolution, Endocrinology, Embryology, and Pathology of Sex Determination and Differentiation
https://www.readbyqxmd.com/read/29323065/emerging-role-of-preputial-vascular-pattern-and-postoperative-microvessel-density-in-cases-of-proximal-hypospadias-a-pilot-study
#8
Vishrut Narang, Amita Sen, Minakshi Bhardwaj
INTRODUCTION: Understanding of anatomical vascular patterns and anatomy of prepuce is critical for a good outcome in hypospadias surgery. A well-vascularized neourethral and preputial flaps used for repair are exceptionally important for a successful outcome, especially in cases of proximal hypospadias undergoing one-stage procedures. OBJECTIVE: To evaluate the vascular anatomy of prepuce in cases of proximal hypospadias and to evaluate microvessel density (MVD) by immunohistochemistry and its correlation with postoperative complications...
October 2017: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/29247355/optimisation-of-sonourethrography-the-clamp-method
#9
Juan de Dios Berná-Mestre, Thierry Balmaceda, Diego Martínez, Jose F Escudero, Gloria Martínez, José A García, Manuel Canteras, Juan D Berná-Serna
PURPOSE: To describe the clamp method for performing retrograde sonourethrography (RSUG) and contrast-enhanced voiding sonourethrography (CE-VSUG) via the transperineal approach in male adults. MATERIALS AND METHODS: Prospective study of 113 males (14-86 years) with urethral strictures confirmed by urethrography who received sonourethrography via the clamp method between 2011 and 2015. The characteristic parameters of the quantitative variables were calculated and a comparative analysis of the qualitative variables was conducted using the McNemar test...
December 15, 2017: European Radiology
https://www.readbyqxmd.com/read/29234534/comparison-of-interrupted-and-continuous-suture-urethroplasty-in-tubularised-incised-plate-hypospadias-repair-a-prospective-study
#10
Archika Gupta, Rajesh Gupta, Punit Srivastav, Ankush Gupta
Objective: To compare the effect of interrupted- and continuous-suture urethroplasty on complication rates in Snodgrass tubularised incised-plate (TIP) hypospadias repair. Patients and methods: This was a prospective randomised study comprising 100 boys (age range 1-5 years) with primary subcoronal, distal- and mid-penile hypospadias who underwent repair from October 2010 to March 2015 in a tertiary care hospital. Boys with glanular, recurrent, and proximal hypospadias were excluded from the study...
December 2017: Arab Journal of Urology
https://www.readbyqxmd.com/read/29201519/glans-wings-are-separated-ventrally-by-the-septum-glandis-and-frenulum-penis-mri-documentation-and-surgical-implications
#11
Hüseyin Özbey, Ali Kumbasar
Objective: In the normal human penis, the glans wings are in apposition in the midline ventrally, and are separated by the "septum glandis" and "frenulum" of the prepuce. However, most of the hypospadias repair techniques include dissection of the glans wings and their approximation enclosing the neourethra within the glans. Material and methods: In order to obtain detailed information about the normal anatomy of glans penis, magnetic resonance imaging (MRI) findings of the penis were studied in three adults...
December 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/29183664/distal-urethral-plate-adhesions-new-anatomical-perspective-in-hypospadias
#12
Marcel Drlík, Radim Kočvara, Josef Sedláček, Zdeněk Dítě, Ivana Vítková, Martin Komarc
INTRODUCTION: We found midline epithelial adhesions in the glandar urethral plate in patients with hypospadias. After dissolution, a blind epithelized channel becomes visualized inside of the plate pointing to immature embryonic luminization. In addition it reveals that the epithelized surface of the distal urethral plate is larger than previously considered. OBJECTIVE: To determine the incidence and extent of these new anatomical details of urethral plate in hypospadias patients...
November 17, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29174377/testosterone-prior-to-hypospadias-repair-postoperative-complication-rates-and-long-term-cosmetic-results-penile-length-and-body-height
#13
S P Rynja, T P V M de Jong, J L H R Bosch, L M O de Kort
INTRODUCTION: The use of hormonal therapy was first described in 1971 before hypospadias surgery, and it has been debated ever since. The long-term outcomes after puberty of patients treated with pre-operative testosterone in childhood are lacking. OBJECTIVES: Possible long-term effects of testosterone are often asked about in daily practice. The current study investigated the long-term outcomes regarding height, penile length and penile cosmesis in adult men after hypospadias surgery in childhood with and without pre-operative testosterone...
February 2018: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29155192/external-genital-development-urethra-formation-and-hypospadias-induction-in-guinea-pig-a-double-zipper-model-for-human-urethral-development
#14
Shanshan Wang, Mingxin Shi, Dongqing Zhu, Ranjiv Mathews, Zhengui Zheng
OBJECTIVE: To determine whether the guinea pig phallus would be an appropriate model of human penile development, we characterized the embryology and sexual differentiation of guinea pig external genitalia and attended to induce hypospadias in males and tubular urethra formation in females pharmacologically. MATERIALS AND METHODS: The external genitalia of guinea pig were collected from genital swelling initiation to newborn stages, and scanning electronic microscopy and histology were performed to visualize the morphology and structure...
March 2018: Urology
https://www.readbyqxmd.com/read/29155191/ultrasound-guided-pudendal-block-is-a-viable-alternative-to-caudal-block-for-hypospadias-surgery-a-single-surgeon-pilot-study
#15
Sarah Hecht, Jorge Piñeda, Aaron Bayne
OBJECTIVE: To evaluate pudendal nerve block as an alternative to caudal block for hypospadias surgery. METHODS: Data were obtained by chart review. Children who underwent hypospadias repair between 2012 and 2016 by a single surgeon at an academic institution were included. Patients received ultrasound-guided pudendal block (n = 21) or caudal block (n = 19) as a regional adjunct to general anesthesia. Primary outcomes included analgesic requirement and postoperative length of stay in the recovery unit...
March 2018: Urology
https://www.readbyqxmd.com/read/29144927/re-can-separation-of-the-scrotal-sac-in-proximal-hypospadias-reliably-predict-the-need-for-urethral-plate-transection
#16
Douglas A Canning
No abstract text is available yet for this article.
December 2017: Journal of Urology
https://www.readbyqxmd.com/read/29135145/-aesthetic-criteria-in-surgical-treatment-of-hypospadias-in-children
#17
G V Kozyrev, A A Protasov, V V Nikolaev, F K Abdullaev, G A Abdulkarimov, M E Karmanov
Aesthetically acceptable cosmetic results of surgical correction of external genital organ defects are important for treatment evaluation along with well-known criteria of good functional outcomes.The purpose of this study was to improve the results of treating children with hypospadias by improving the assessment of results and introducing multi-step correction modalities. MATERIALS AND METHODS: From 2013 to 2015, 476 patients with various forms of hypospadias were treated at the Department of Uroandrology of RCCH...
October 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/29133164/pre-incision-urethral-plate-width-does-not-impact-short-term-tubularized-incised-plate-urethroplasty-outcomes
#18
N C Bush, W Snodgrass
INTRODUCTION: Two reports have found that urethral plate (UP) widths <8 mm before tubularized incised plate (TIP) incision increased urethroplasty complications. The present study measured pre-incision UP width in consecutive boys undergoing TIP to determine if it affected outcomes. METHODS: The present study followed the method previously used by Holland and Smith, and Sarhan et al. to measure UP width before creating glans wings or performing midline plate incision in consecutive patients with primary hypospadias and ventral curvature <30°, who all underwent TIP repair (Summary Fig...
December 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29061174/de-novo-chromosome-7q36-1q36-2-triplication-in-a-child-with-developmental-delay-growth-failure-distinctive-facial-features-and-multiple-congenital-anomalies-a-case-report
#19
Muna A Al Dhaibani, Diane Allingham-Hawkins, Ayman W El-Hattab
BACKGROUND: Studying human genome using chromosomal microarrays has significantly improved the accuracy and yield of diagnosing genomic disorders. Chromosome 7q36 deletions and duplications are rare genomic disorders that have been reported in a limited number of children with developmental delay, growth retardation, and congenital malformation. Altered dosage of SHH and HLXB9, both located in 7q36.3, is believed to play roles in the phenotypes associated with these rearrangements. In this report we describe a child with 7q36...
October 23, 2017: BMC Medical Genetics
https://www.readbyqxmd.com/read/29043694/-long-term-results-of-hypospadias-surgery-urinary-and-sexual-function-and-psychological-impact
#20
J Rojas-Ticona, G Zambudio Carmona, L Delmas Benito, M Fernández-Ibieta, P Y Reyes Ríos, I Martínez Castaño, V Villamil, A Sánchez Sánchez, M J Guirao Piñera, J I Ruiz Jiménez
OBJECTIVES: To determine the current status of the patients operated on for hypospadias in our region, in order to adapt the surgical technique to their real needs. MATERIAL AND METHODS: A descriptive and observational study. Interviews were conducted with hypospadias surgery patients in our hospital between 1976 and 1996, focusing on their urinary and sexual function and psychological impact. We performed a descriptive statistical analysis and comparisons between types of hypospadias (SPSSv19)...
July 20, 2017: Cirugía Pediátrica: Organo Oficial de la Sociedad Española de Cirugía Pediátrica
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