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Aseptic meningitis

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https://www.readbyqxmd.com/read/28327792/vegetation-loss-and-the-2016-oropouche-fever-outbreak-in-peru
#1
Daniel Romero-Alvarez, Luis E Escobar
BACKGROUND: Oropouche virus causes Oropouche fever, an arboviral disease transmitted mainly by midges of the genus Culicoides and Culex mosquitoes. Clinical presentation of Oropouche fever in humans includes fever, headache, rash, myalgia, and in rare cases spontaneous bleeding and aseptic meningitis. Landscape change has been proposed as a driver of Oropouche fever emergence. OBJECTIVE: To investigate the landscape epidemiology of the Oropouche fever outbreak that began in April 2016 in Cusco, Peru...
April 2017: Memórias do Instituto Oswaldo Cruz
https://www.readbyqxmd.com/read/28291512/recurrent-trimethoprim-sulfamethoxazole-induced-aseptic-meningitis-with-associated-ampicillin-induced-myoclonic-twitches%C3%A2
#2
Anna Lena Fisse, Katrin Straßburger-Krogias, Ralf Gold, Gisa Ellrichmann
OBJECTIVE: To report a case of recurrent trimethoprim-sulfamethoxazole-induced aseptic meningitis with associated ampicillin-induced myoclonic twitches. MATERIALS AND METHODS: The patient was investigated using cerebral computed tomography, magnetic resonance imaging, cerebrospinal fluid examination, and electroencephalography. Written informed consent was obtained from the patient for access to clinical files for research purposes and publication. RESULTS: We present a middle-aged woman with two recurrent episodes of aseptic meningitis after treatment with trimethoprim-sulfamethoxazole...
March 14, 2017: International Journal of Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28273990/neurological-manifestations-in-systemic-lupus-erythematosus-a-single-centre-study-from-north-east-india
#3
Sanjeeb Kakati, Bhupen Barman, Sobur U Ahmed, Masaraf Hussain
INTRODUCTION: Neurological manifestations although common in Systemic Lupus Erythematosus (SLE), are often not recognized due to their diversed and varied presentation. Therefore, the study was planned to highlight the pattern of neurological involvement in SLE to help in early recognition. AIM: To study the pattern of neurological involvement in SLE and its correlation with disease activity and different investigation. MATERIALS AND METHODS: This hospital based prospective observational study was carried out from August 2009 to July 2010...
January 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28262401/natural-history-of-headache-in-patients-with-lymphocytic-meningitis-following-lumbar-puncture
#4
Alexander Khlebtovsky, Shlomit Yust-Katz, Arieh Kuritzky, Israel Steiner
BACKGROUND: Analysis of cerebrospinal fluid (CSF) obtained by lumbar puncture (LP) is essential for diagnosis of meningitis. What is the impact of the procedure upon the natural history of headache and associated signs in patients with lymphocytic meningitis and what factors can have prognostic value for the future progression of symptomatology? This study was aimed at looking into these questions. METHODS: One hundred and one patients with clinical and laboratory diagnosis of aseptic meningitis answered a questionnaire intended at assessing the severity and nature of headache and meningeal irritation signs before and one, and twenty four hours after the LP...
March 2, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28237695/seroprevalence-study-of-toscana-virus-and-viruses-belonging-to-the-sandfly-fever-naples-antigenic-complex-in-central-and-southern-italy
#5
Serena Marchi, Claudia M Trombetta, Otfried Kistner, Emanuele Montomoli
Sandfly fever viruses are transmitted by the bite of phlebotomine sandflies; serotypes sandfly fever Naples virus, sandfly fever Sicilian virus and sandfly fever Cyprus virus cause febrile illness, whereas Toscana virus (TOSV) may cause neuroinvasive infections. Although TOSV is an important cause of aseptic meningitis in central and southern Italy, in many cases the infection is asymptomatic, leading to underestimation of the actual spread of the virus. This serosurvey aimed to assess the seroprevalence of TOSV in a random population in Siena (Tuscany, central Italy) in 2003-2004 and 2013-2014 and Bari (Apulia, southern Italy) in 2004 and 2015...
February 22, 2017: Journal of Infection and Public Health
https://www.readbyqxmd.com/read/28225788/molecular-detection-and-genotyping-of-enteroviruses-from-csf-samples-of-patients-with-suspected-sepsis-like-illness-and-or-aseptic-meningitis-from-2012-to-2015-in-west-bank-palestine
#6
Kamal Dumaidi, Amer Al-Jawabreh
BACKGROUND: Human enteroviruses (HEVs) are the most frequently reported cause of aseptic meningitis with or without CSF pleocytosis in childhood. Rapid detection and genotype of HEVs is essential to determine the causative agent and variant causing sepsis-like illness and/or aseptic meningitis. AIM: To investigate the molecular epidemiology of enteroviruses (EVs) among patients with sepsis-like illness and/or aseptic meningitis admitted to three major hospitals in West Bank, Palestine from 2012 to 2015...
2017: PloS One
https://www.readbyqxmd.com/read/28214758/comparative-analysis-of-viral-shedding-in-pediatric-and-adult-subjects-with-central-nervous-system-associated-enterovirus-infections-from-2013-to-2015-in-switzerland
#7
S Cordey, M Schibler, A G L'Huillier, N Wagner, A R Gonçalves, J Ambrosioni, S Asner, L Turin, K M Posfay-Barbe, L Kaiser
BACKGROUND: Several enterovirus (EV) genotypes can result in aseptic meningitis, but their routes of access to the central nervous system remain to be elucidated and may differ between the pediatric and adult populations. OBJECTIVE: To assess the pattern of viral shedding in pediatric and adult subjects with acute EV meningitis and to generate EV surveillance data for Switzerland. STUDY DESIGN: All pediatric and adult subjects admitted to the University Hospitals of Geneva with a diagnosis of EV meningitis between 2013 and 2015 were enrolled...
April 2017: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/28196635/childhood-meningitis-in-kuwait-in-the-era-of-post-pneumococcal-conjugate-vaccination-a-multicenter-study
#8
Hussain Sadeq, Entesar H Husain, Amna Alkoot, Suha Atyani, Abdullah Al-Fraij, Abdulrahman Al-Daithan, Talal AlSaleem, Anfal Taher, May Alenezi
This is a retrospective study to evaluate epidemiology and etiologies of childhood meningitis in Kuwait after the routine introduction of the pneumococcal conjugate vaccine. The data was collected from 196 patients in the period of 2010-2014. Aseptic meningitis accounted for 51% of the cases, bacterial meningitis accounted for 29% cases and partially treated meningitis were 20%. Organisms causing bacterial meningitis were: Streptococcus pneumoniae 40.4%, Neisseria meningitidis 17.6%, Haemophilus spp. 12.2%, other gram positive or negative 19...
February 9, 2017: Journal of Infection and Public Health
https://www.readbyqxmd.com/read/28195100/a-54-year-old-male-with-rapidly-progressive-neurologic-syndrome-clinicopathologic-correlation-of-a-rare-diagnosis
#9
Deepti Mutreja, Nikhil Moorchung, Salil Gupta, Rajeev Saxena, Rohini S Doshetty, Bhaskar Nandi
Diagnosis of systemic lupus erythematosus (SLE) as primary presentation with central nervous system involvement as a rapidly progressive neurologic syndrome is extremely rare. We present a rare case of a 54-year-old hypertensive male patient, who presented with a fulminant neurologic syndrome. He presented with cerebellar and meningeal signs, aseptic meningitis and had a rapid downhill course following admission. A postmortem revealed feature of systemic connective tissue fulfilling diagnostic criteria of SLE with lupus cerebritis...
January 2017: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/28165786/trimethoprim-induced-aseptic-meningism
#10
Mary Ni Lochlainn, Hock C Gooi, Monday O Ogese, Dean J Naisbitt, Bahram Jafar-Mohammadi
No abstract text is available yet for this article.
February 2, 2017: British Journal of Hospital Medicine
https://www.readbyqxmd.com/read/28164314/a-probable-case-of-west-nile-virus-transfusion-transmission
#11
Jamel A Groves, Hedyeh Shafi, Jim H Nomura, Ross M Herron, Devin Baez, Roger Y Dodd, Susan L Stramer
BACKGROUND: Transfusion-transmitted West Nile virus (WNV) infection is infrequent as a result of minipool (MP) and individual-donation (ID) nucleic acid testing (NAT) of blood donations. ID-NAT is triggered on the basis of local WNV activity identified by MP-NAT. STUDY DESIGN AND METHODS: A 78-year-old male patient who was treated for cardiac disease received 14 blood components from 30 donors in August 2016. He was discharged 7 days after aortic valve replacement and coronary bypass surgery, but was re-admitted on Day 12 with symptoms of viral infection, and eventually was diagnosed with aseptic meningitis...
February 5, 2017: Transfusion
https://www.readbyqxmd.com/read/28134085/digenic-mefv-tnfrsf1a-autoinflammatory-syndrome-with-relapsing-aseptic-neutrophilic-meningitis-and-chronic-myelitis
#12
Anne Murarasu, Catherine Dodé, Guillaume Sarrabay, Isabelle Klein, Thomas Papo, Karim Sacré
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January 26, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28121938/comparison-of-posterior-fossa-decompression-with-and-without-duraplasty-for-the-surgical-treatment-of-chiari-malformation-type-i-in-adult-patients-a-retrospective-analysis-of-103-patients
#13
COMPARATIVE STUDY
Junchen Chen, Yongning Li, Tianyu Wang, Jun Gao, Jincheng Xu, Runlong Lai, Dianhui Tan
Chiari malformation type I (CM-I) is a congenital neurosurgical disease about the herniation of cerebellar tonsil through the foramen magnum. A variety of surgical techniques for CM-I have been used, and there is a controversy whether to use posterior fossa decompression with duraplasty (PFDD) or posterior fossa decompression without duraplasty (PFD) in CM-I patients. Here, we compared the clinical results and effectiveness of PFDD and PFD in adult patients with CM-I. The cases of 103 adult CM-I patients who underwent posterior fossa decompression with or without duraplasty from 2008 to 2014 were reviewed retrospectively...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28118536/csf-cytokines-correlate-with-aseptic-meningitis-and-blood-brain-barrier-function-in-neonatal-onset-multisystem-inflammatory-disease-nomid
#14
Jackeline Rodriguez-Smith, Yen-Chih Lin, Wanxia Li Tsai, Hanna Kim, Gina Montealegre-Sanchez, Dawn Chapelle, Yan Huang, Cailin H Sibley, Massimo Gadina, Robert Wesley, Bibiana Bielekova, Raphaela Goldbach-Mansky
OBJECTIVE: To evaluate proinflammatory cytokines and leukocyte subpopulations in cerebrospinal spinal fluid (CSF) and blood of NOMID patients post-treatment; and to compare inflammatory cytokines in CSF and blood in 6 patients treated with two IL-1 blockers, anakinra and canakinumab. METHODS: We immunophenotyped CSF on 17 anakinra-treated pediatric NOMID patients during routine follow-up visits between December 2011 and October 2013 and analyzed CSF cytokine levels in baseline and 3-5 years follow-up samples compared to healthy controls...
January 24, 2017: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/28071799/seroepidemiological-and-phylogenetic-characterisation-of-neurotropic-enteroviruses-in-ireland-2005-2014
#15
Jorge Abboud Guerra, Allison Waters, Alison Kelly, Ursula Morley, Paul O'Reilly, Edwin O'Kelly, Jonathan Dean, Robert Cunney, Piaras O'Lorcain, Suzanne Cotter, Jeff Connell, Joanne O'Gorman, William W Hall, Michael Carr, Cillian F De Gascun
Enteroviruses (EVs) are associated with a broad spectrum of clinical presentation, including aseptic meningitis (AM), encephalitis, hand, foot and mouth disease, acute flaccid paralysis and acute flaccid myelitis. Epidemics occur sporadically and are associated with increased cases of AM in children. The present study describes the seroepidemiological analysis of circulating EVs in Ireland from 2005-2014 and phylogenetic characterisation of echovirus 30 (E-30), enterovirus A71 (EV-A71) and enterovirus D68 (EV-D68)...
January 10, 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/28056277/-direct-medical-costs-and-influencing-factors-in-severe-hand-foot-and-mouth-disease-in-children-aged-between-six-months-and-five-years-old
#16
Y M Zheng, J Yang, Q H Liao
Objective: To estimate the direct medical cost of severe hand, foot and mouth disease (HFMD) in patients aged less than five years. Methods: A stratified sampling method was used to collect data on severe HFMD cases reported in the National HFMD surveillance database between Jan 1, 2012, and Dec 31, 2013. The sampling was referenced with the national aetiologic distribution of Enterovirus A71 (EV-A71), Coxsackievirus A16 (CV-A16) and other Enteroviruses (OEV) for severe HFMD cases and the included cases were distributed among seven geographic regions (Northeast, North China, Northwest, Central China, Southwest, East China and South China)...
January 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28011278/molecular-characterization-of-echovirus-13-uncovering-high-genetic-diversity-and-identification-of-new-genotypes-in-pakistan
#17
Shahzad Shaukat, Mehar Angez, Tariq Mahmood, Muhammad Masroor Alam, Salmaan Sharif, Adnan Khurshid, Muhammad Suleman Rana, Syed Sohail Zahoor Zaidi
Echovirus 13 (E-13) is reported worldwide and is mostly related to aseptic meningitis but it is also isolated from cases of acute flaccid paralysis (AFP). Unfortunately, all studies conducted on non polio enterovirus in Pakistan only confirm E-13 isolation based on microneutralization assay but there is lack of molecular epidemiological data on this serotype. In this study, 113 stool samples were collected from AFP patients during 2008-2010. An enterovirus primer mediated real-time reverse transcriptase polymerase chain reaction, a standard microneutralization assay and sequencing of viral protein 1 gene (VP1) identified the predominant serotype E-13...
December 20, 2016: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/28007669/a-case-of-aseptic-meningitis-without-neck-rigidity-occurring-in-a-metastatic-melanoma-patient-treated-with-ipilimumab
#18
Kyosuke Oishi, Masaharu Nakao, Shintaro Maeda, Takashi Matsushita, Tokuhei Ikeda, Tadaaki Yamada, Kazuhiko Takehara, Yasuhito Hamaguchi
No abstract text is available yet for this article.
December 22, 2016: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/27976418/semiparametric-time-varying-coefficient-model-for-matched-case-crossover-studies
#19
Ana Maria Ortega-Villa, Inyoung Kim, H Kim
In matched case-crossover studies, it is generally accepted that the covariates on which a case and associated controls are matched cannot exert a confounding effect on independent predictors included in the conditional logistic regression model. This is because any stratum effect is removed by the conditioning on the fixed number of sets of the case and controls in the stratum. Hence, the conditional logistic regression model is not able to detect any effects associated with the matching covariates by stratum...
December 15, 2016: Statistics in Medicine
https://www.readbyqxmd.com/read/27957363/aseptic-meningitis-caused-by-lassa-virus-case-series-report
#20
Peter O Okokhere, Idowu A Bankole, Christopher O Iruolagbe, Benard E Muoebonam, Martha O Okonofua, Simeon O Dawodu, George O Akpede
The Lassa virus is known to cause disease in different organ systems of the human body, with varying clinical manifestations. The features of severe clinical disease may include bleeding and/or central nervous system manifestations. Whereas Lassa fever encephalopathy and encephalitis are well described in the literature, there is paucity of data on Lassa virus meningitis. We present the clinical description, laboratory diagnosis, and management of 4 consecutive cases of aseptic meningitis associated with Lassa virus infection without bleeding seen in a region of Nigeria known to be endemic for both the reservoir rodent and Lassa fever...
2016: Case Reports in Neurological Medicine
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