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Hyperglycemia in hospital

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https://www.readbyqxmd.com/read/29450496/association-of-metabolic-syndrome-with-sudden-sensorineural-hearing-loss
#1
Su Young Jung, Haeng Seon Shim, Young Min Hah, Sang Hoon Kim, Seung Geun Yeo
Importance: Each of the 5 diagnostic criteria or factors of metabolic syndrome-hyperglycemia or type 2 diabetes, hypertension, obesity, elevated triglyceride levels, and decreased high-density lipoprotein cholesterol level-is associated with the pathophysiologic features of sudden sensorineural hearing loss (SSNHL). Little is known, however, about the association of metabolic syndrome, defined as the presence of at least 3 of these factors, with the prognosis of SSNHL. Objective: To evaluate the association of metabolic syndrome with the rate of recovery from SSNHL...
February 15, 2018: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29446580/is-there-any-difference-between-the-symptomatology-and-clinical-findings-of-viral-agents-causing-dehydration
#2
Suat Biçer, Defne Çöl, Öznur Küçük, Gülay Ç Erdağ, Tuba Giray, Meltem Uğraş, Ayça Vitrinel, Çiğdem Kaspar
BACKGROUND: Acute gastroenteritis is responsible for dehydration in many children. The viruses like rotavirus, norovirus, and adenovirus are considered the main causative agents of gastroenteritis. The goal of this study is the evaluation of the symptoms, clinical findings and hospitalization requirements in pediatric patients with dehydration secondary to viral gastroenteritis. METHODS: The distribution of age, symptoms, clinical and laboratory findings and hospitalization requirements of 156 viral acute gastroenteritis patients with moderate dehydration were evaluated retrospectively...
April 2018: Minerva Pediatrica
https://www.readbyqxmd.com/read/29442175/common-models-used-for-inpatient-diabetes-management
#3
REVIEW
Andjela T Drincic, Padmaja Akkireddy, Jon T Knezevich
PURPOSE OF REVIEW: Diabetes affects about a third of all hospitalized patients and up to 50% of inpatients go on to experience hyperglycemia. Despite strong evidence supporting the importance of adequate glycemic control, as well detailed guidelines from major national organizations, many patients continue to have hypo- and hyperglycemia during their hospital stay. While this may be partially related to provider and patient-specific factors, system-based barriers continue to pose a major obstacle...
February 14, 2018: Current Diabetes Reports
https://www.readbyqxmd.com/read/29430446/models-of-disuse-muscle-atrophy-therapeutic-implications-in-critically-ill-patients
#4
REVIEW
Esther Barreiro
Skeletal muscle weakness is common in the intensive care units (ICU). Approximately 50% of patients under mechanical ventilation for more than 7 days show signs of ICU-acquired muscle weakness. In these patients, muscle weakness may be the result of axonal polyneuropathy, myopathy or a combination of both. The commonest risk factors in patients with ICU-acquired weakness (AW) are the severity and duration of the systemic inflammatory response, duration of the stay in the ICU and of mechanical ventilation, hyperglycemia, hypoalbuminemia, parenteral nutrition, and administration of corticosteroids and of neuromuscular blocking agents...
January 2018: Annals of Translational Medicine
https://www.readbyqxmd.com/read/29428103/risk-factors-and-metabolic-abnormality-of-patients-with-non-alcoholic-fatty-liver-disease-either-non-obese-or-obese-chinese-population
#5
Shou-Wu Lee, Teng-Yu Lee, Sheng-Shun Yang, Chun-Fang Tung, Hong-Zen Yeh, Chi-Sen Chang
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) occurs not only in obese individuals but also in non-obese ones. The aim of this study was to focus on the association between NAFLD and metabolic events in a non-obese or obese Chinese population. METHODS: Data collected from subjects registered at Taichung Veterans General Hospital from January to December 2009 were analyzed. The exclusion criteria were alcoholics, chronic hepatitis B or C. Patients included in analyses were assigned to four groups according to sonography of their liver (normal or NAFLD), and body mass index (BMI) levels (non-obese if BMI < 25 kg/m 2 or obese if BMI ≥ 25 kg/m 2 )...
February 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/29408836/pathophysiological-response-to-burn-injury-in-adults
#6
Mile Stanojcic, Abdikarim Abdullahi, Sarah Rehou, Alexandra Parousis, Marc G Jeschke
OBJECTIVE: The aim of this study was to compare the hypermetabolic, and inflammatory trajectories in burned adults to gain insight into the pathophysiological alterations and outcomes after injury. SUMMARY OF BACKGROUND DATA: Burn injury leads to a complex response that is associated with hypermetabolism, morbidity, and mortality. The underlying pathophysiology and the correlations between humoral changes and organ function have not been well delineated in adult burn patients...
March 2018: Annals of Surgery
https://www.readbyqxmd.com/read/29407051/hyperglycemia-in-acute-coronary-syndromes-from-mechanisms-to-prognostic-implications
#7
REVIEW
Mikhail Kosiborod
Numerous studies have documented that hyperglycemia is frequent in patients hospitalized with acute coronary syndromes, affects patients with and without established diabetes, and is associated with adverse outcomes, with incremental increase in risk of mortality and complications observed across the spectrum of glucose elevations. This article reviews present knowledge about the association between glucose levels and outcomes of patients hospitalized with acute coronary syndromes; describes available data regarding inpatient glucose management in this patient group, and comparative data across the spectrum of critically ill hospitalized patients; addresses some controversies in this field; and offers practical recommendations for patient management based on existing data...
March 2018: Endocrinology and Metabolism Clinics of North America
https://www.readbyqxmd.com/read/29402368/-efficacy-and-safety-of-simulated-artificial-pancreas-in-modulating-stress-hyperglycemia-in-critically-ill-patients-a-prospective-randomized-controlled-study
#8
Zhongliang Yang, Guoqiang Tao, Meifeng Guo, Baoling Sun, Liang Gong, Yong Ding, Shuming Ye, Weidong Liu, Xiuyun Yang
OBJECTIVE: To explore efficacy and safety of simulated artificial pancreas in modulating stress hyperglycemia in critically ill patients. METHODS: A prospective randomized controlled study was performed. Seventy-two critically ill patients with stress hyperglycemia, aged 18-85 years, acute physiology and chronic health evaluation II (APACHE II) score over 15, two consecutive random blood glucose 11.1 mmol/L or higher, glycated hemoglobin (HbA1C) below 0.065, unable to eat food for 3 days after inclusion, or only accepting parenteral nutrition, admitted to intensive care unit (ICU) in Shanghai Punan Hospital of Pudong New District from January 1st, 2015 to June 30th, 2017 were enrolled...
February 2018: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/29395641/the-burden-of-diabetes-and-the-chance-of-a-previous-stroke-thrombolysis-for-recurrent-stroke-in-diabetics
#9
Alexandra Filipov, Anne D Ebert, Eva Neumaier-Probst, Angelika Alonso
BACKGROUND: Intravenous thrombolysis with recombinant tissue plasminogen activator is still not approved by the European Medicines Agency for patients with diabetes mellitus and previous stroke. We assessed functional benefit and potential risk of thrombolysis in patients with diabetes and previous stroke and the influence of age, preexisting diabetic damage, as well as acute and chronic hyperglycemia on outcome, symptomatic intracranial hemorrhage, and in-hospital mortality. METHODS: We analyzed 527 consecutive patients treated with thrombolysis for acute stroke...
January 26, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29391105/hyperglycemia-is-associated-with-surgical-site-infections-among-general-and-vascular-surgery-patients
#10
Amy Showen, Tara A Russell, Stephanie Young, Sachin Gupta, Melinda M Gibbons
Surgical site infection (SSI) is a common cause of morbidity in general and vascular surgery patients. There is inconsistent evidence on the association of glycemic status with SSI, and its utility in predicting and mitigating SSI. General and vascular surgery patients at a public teaching hospital had the following markers of glycemic status prospectively collected: preoperative hemoglobin A1c (HbA1c) and capillary blood glucose (cBG, within six months before surgery), perioperative cBG (within 24 hours before surgery), and postoperative cBG (peak value up to 48 hours after surgery)...
October 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/29385933/gestational-impaired-glucose-tolerance-gigt-induced-suppression-of-fetal-thyroid-secretion-effect-on-fetal-outcome
#11
Suganya Shanmugam, Pooja Dhiman, Soundravally Rajendiran, Archana Nimesh, Dilip Kumar Maurya
INTRODUCTION: Gestational impaired glucose tolerance (GIGT) is a milder form of gestational diabetes mellitus (GDM), which is often poorly managed. Although, GDM is known to be associated with increased incidence of thyroid dysfunction, no study has been done to study the effect of GIGT on thyroid status and its effect on fetal outcome. Here, we carried out a study to assess thyroid function and glycemic status in both maternal and cord blood of the subjects with GIGT, and to find their association with the fetal outcome...
January 31, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29382659/prognostic-value-of-the-acute-to-chronic-glycemic-ratio-at-admission-in-acute-myocardial-infarction-a-prospective-study
#12
Giancarlo Marenzi, Nicola Cosentino, Valentina Milazzo, Monica De Metrio, Milena Cecere, Susanna Mosca, Mara Rubino, Jeness Campodonico, Marco Moltrasio, Ivana Marana, Marco Grazi, Gianfranco Lauri, Alice Bonomi, Fabrizio Veglia, Roberto Manfrini, Antonio L Bartorelli
OBJECTIVE: Acute hyperglycemia is a powerful predictor of poor prognosis in acute myocardial infarction (AMI), particularly in patients without diabetes. This emphasizes the importance of an acute glycemic rise rather than glycemia level at admission alone. We investigated in AMI whether the combined evaluation of acute and chronic glycemic levels, as compared with admission glycemia alone, may have a better prognostic value. RESEARCH DESIGN AND METHODS: We prospectively measured admission glycemia and estimated average chronic glucose levels (mg/dL) by the following formula: [(28...
January 30, 2018: Diabetes Care
https://www.readbyqxmd.com/read/29357807/hyperglycemia-in-hospitalized-diabetic-non-critically-ill-patients-prevalence-correlates-management-and-nurses-attitudes
#13
Ghada El Khoury, Hanine Mansour, Wissam Kabbara, Nibal Chamoun, Nadim Attalah, Pascale Salameh
BACKGROUND: Diabetes Mellitus is a chronic metabolic disease that affects 387 million people around the world. Episodes of hyperglycemia in hospitalized diabetic patients are associated with poor clinical outcomes and increased morbidity and mortality. Therefore, prevention of hyperglycemia is critical to, decrease length of hospital stay and to reduce complications and readmissions. OBJECTIVE: The study aims to examine the prevalence of hyperglycemia and assess the correlates and management of hyperglycemia in diabetic non-critically ill patients...
January 19, 2018: Current Diabetes Reviews
https://www.readbyqxmd.com/read/29350603/decision-tree-analysis-in-subarachnoid-hemorrhage-prediction-of-outcome-parameters-during-the-course-of-aneurysmal-subarachnoid-hemorrhage-using-decision-tree-analysis
#14
Isabel Charlotte Hostettler, Carl Muroi, Johannes Konstantin Richter, Josef Schmid, Marian Christoph Neidert, Martin Seule, Oliver Boss, Athina Pangalu, Menno Robbert Germans, Emanuela Keller
OBJECTIVE The aim of this study was to create prediction models for outcome parameters by decision tree analysis based on clinical and laboratory data in patients with aneurysmal subarachnoid hemorrhage (aSAH). METHODS The database consisted of clinical and laboratory parameters of 548 patients with aSAH who were admitted to the Neurocritical Care Unit, University Hospital Zurich. To examine the model performance, the cohort was randomly divided into a derivation cohort (60% [n = 329]; training data set) and a validation cohort (40% [n = 219]; test data set)...
January 19, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29346740/role-of-the-diabetes-educator-in-inpatient-diabetes-management
#15
(no author information available yet)
It is the position of American Association of Diabetes Educators (AADE) that all inpatient interdisciplinary teams include a diabetes educator to lead or support improvement efforts that affect patients hospitalized with diabetes or hyperglycemia. This not only encompasses patient and family education but education of interdisciplinary team members and achievement of diabetes-related organizational quality metrics and performance outcomes.
February 2018: Diabetes Educator
https://www.readbyqxmd.com/read/29330638/predictors-of-severe-postoperative-hyperglycemia-after-cardiac-surgery-in-infants-a-single-center-retrospective-observational-study
#16
Natsuhiro Yamamoto, Tomoya Irie, Shunsuke Takaki, Osamu Yamaguchi, Takahisa Goto
PURPOSE: Hyperglycemia is a common issue in infants after cardiac surgery for congenital heart disease. Poor glycemic control is suspected to be associated with adverse postoperative outcomes. This study was performed to investigate clinical factors contributing to hyperglycemia in the perioperative period in infats. METHODS: A total of 69 infants (aged 1-12 months) who were admitted to Yokohama City University Hospital Intensive Care Unit (ICU) after surgical repair of congenital heart diseases with cardiopulmonary bypass (CPB) were retrospectively analysed...
January 12, 2018: Journal of Anesthesia
https://www.readbyqxmd.com/read/29316157/dapagliflozin-for-prednisone-induced-hyperglycemia-in-acute-exacerbation-of-chronic-obstructive-pulmonary-disease
#17
Maaike C Gerards, Gerdien E Venema, Kornelis W Patberg, Martijn Kross, Bert Jan Potter van Loon, Ilse M G Hageman, Dominic Snijders, Dees P M Brandjes, Joost B L Hoekstra, Titia M Vriesendorp, Victor E A Gerdes
This study aimed to compare the effectiveness and safety of add-on treatment with dapagliflozin to placebo in subjects with prednisone-induced hyperglycemia during treatment for acute exacerbation of chronic obstructive pulmonary disease (AECOPD). We enrolled 46 patients hospitalized for an AECOPD in a multicenter double-blind randomized controlled study in which add-on treatment with dapagliflozin 10 mg was compared to placebo. Glycemic control and incidence of hypoglycemia were measured through a blinded subcutaneous continuous glucose measurement device...
January 5, 2018: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/29304923/potentially-modifiable-risk-factors-for-long-term-cognitive-impairment-after-critical-illness-a-systematic-review
#18
REVIEW
Amra Sakusic, John C O'Horo, Mikhail Dziadzko, Dziadzko Volha, Rashid Ali, Tarun D Singh, Rahul Kashyap, Ann M Farrell, John D Fryer, Ronald Petersen, Ognjen Gajic, Alejandro A Rabinstein
Long-term cognitive impairment is common in survivors of critical illness. Little is known about the etiology of this serious complication. We sought to summarize current scientific knowledge about potentially modifiable risk factors during intensive care unit (ICU) treatment that may play a substantial role in the development of long-term cognitive impairment. All searches were run on October 1, 2017. The search strategy included Ovid MEDLINE, Ovid Embase, Ovid CDR, Cochrane Central Register of Controlled Trials and Database of Abstracts of Reviews of Effect, Scopus, and Web of Science, and included MeSH headings and keywords related to intensive care, critical care, and cognitive disorders...
January 2018: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/29289983/intensified-blood-glucose-treatment-in-diabetic-patients-undergoing-a-liver-transplant-impact-on-graft-evolution-at-3%C3%A2-months-and-at-5%C3%A2-years
#19
A Ramos-Prol, D Hervás-Marín, B Rodríguez-Medina, M Rubio-Almanza, M Berenguer, Á Moya-Herraiz, J F Merino-Torres
PURPOSE: The debate about the impact of intensified hyperglycemia treatment is still ranging. The main objective was to assess whether intensive glycemic control in hospitalized diabetic patients undergoing a liver transplant is associated with a lower rate of graft rejection at 3 months and at 5 years post-transplant. METHODS: Cross-sectional study comparing a cohort of patients undergoing liver transplant in 2010 and 2011, in whom an intensive insulin protocol was applied, with a retrospective group of patients undergoing a liver transplant in 2005 and 2006, in whom a conventional insulin protocol was applied...
December 30, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/29285451/the-prevalence-of-new-onset-diabetes-mellitus-after-renal-transplantation-in-patients-with-immediate-posttransplant-hyperglycemia-in-a-tertiary-care-centre
#20
Saba Samad Memon, Nikhil Tandon, Sandeep Mahajan, V K Bansal, Asuri Krishna, Arunkumar Subbiah
Objectives: This study aimed to determine the prevalence of immediate posttransplant hyperglycemia and new onset diabetes after renal transplantation (NODAT). It also aims at answering whether posttransplant hyperglycemia per se is a risk factor for future development of NODAT. Methods: A retrospective study was conducted among patients undergoing kidney transplantation under a single surgical unit in a tertiary care hospital in the past 5 years. All known patients with diabetes were excluded from the study...
November 2017: Indian Journal of Endocrinology and Metabolism
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