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https://www.readbyqxmd.com/read/28810577/patchouli-oil-ameliorates-acute-colitis-a-targeted-metabolite-analysis-of-2-4-6-trinitrobenzenesulfonic-acid-induced-rats
#1
Xiuting Yu, Guanghua Yang, Hua Jiang, Shuhai Lin, Yuhong Liu, Xie Zhang, Huifang Zeng, Ziren Su, Song Huang, Linlin Shen, Xiaojun Zhang
The incidence of inflammatory bowel disease (IBD), characterized by chronic, relapsing intestinal inflammation, has continually increased in recent years. A previous study by our group identified five potential metabolic markers possibly associated with the pathology of 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced IBD in rats. The present study aimed to examine the potential therapeutic effects of the essential oil of Pogostemon cablin (also known as patchouli; PO) on TNBS-induced rats and investigate the concomitant metabolic changes by targeting the previously identified potential markers...
August 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28808930/hospitalization-in-the-year-preceding-major-oncologic-surgery-increases-risk-for-adverse-postoperative-events
#2
Catherine E Sharoky, Karole T Collier, Christopher J Wirtalla, Andrew J Sinnamon, Madalyn G Neuwirth, Lindsay E Kuo, Robert E Roses, Douglas L Fraker, Giorgos C Karakousis, Rachel R Kelz
BACKGROUND: Hospitalization is associated with negative clinical effects that last beyond discharge. This study aimed to determine whether hospitalization in the year before major oncologic surgery is associated with adverse outcomes. METHODS: Patients 18 years of age or older with stomach, pancreas, colon, or rectal cancer who underwent resection in California and New York (2008-2010) were included in the study. Patients with hospitalization in the year prior to oncologic resection (HYPOR) were identified...
August 14, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28806303/does-a-combination-of-laparoscopic-approach-and-full-fast-track-multimodal-management-decrease-postoperative-morbidity-a-multicenter-randomized-controlled-trial
#3
Léon Maggiori, Eric Rullier, Jérémie H Lefevre, Jean-Marc Régimbeau, Stéphane Berdah, Mehdi Karoui, Jérome Loriau, Arnaud Alvès, Eric Vicaut, Yves Panis
OBJECTIVE: The aim of this study was to assess whether association of laparoscopic approach and full fast track multimodal (FFT) management can reduce postoperative morbidity after colorectal cancer surgery, as compared to laparoscopic approach with limited fast-track program (LFT). SUMMARY OF BACKGROUND DATA: Recent advances in colorectal cancer surgery are introduction of laparoscopy and FFT implementation. METHODS: Patients eligible for elective laparoscopic colorectal cancer surgery were randomized into 2 groups: FFT or LFT care (with only early oral intake and mobilization starting on Day 1)...
August 11, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28804436/intake-of-different-types-of-red-meat-poultry-and-fish-and-incident-colorectal-cancer-in-women-and-men-results-from-the-malm%C3%A3-diet-and-cancer-study
#4
Alexandra Vulcan, Jonas Manjer, Ulrika Ericson, Bodil Ohlsson
Background : Colorectal cancer (CRC) is considered one of the most common forms of cancer in the Western world. High intake of red and processed meat is considered to increase CRC development. Objective : This study examined associations between intake of red meats, poultry, and fish and incident CRC, and if weight status modifies the associations. Design : In the Malmö Diet and Cancer Study, dietary data was collected through a modified diet history method. Via the Swedish Cancer Registry, 728 cases of CRC were identified during 428 924 person-years of follow-up of 16 944 women and 10 987 men...
2017: Food & Nutrition Research
https://www.readbyqxmd.com/read/28803329/childhood-body-mass-index-and-height-in-relation-to-site-specific-risks-of-colorectal-cancers-in-adult-life
#5
Britt W Jensen, Michael Gamborg, Ismail Gögenur, Andrew G Renehan, Thorkild I A Sørensen, Jennifer L Baker
As colorectal cancers have a long latency period, their origins may lie early in life. Therefore childhood body mass index (BMI; kg/m(2)) and height may be associated with adult colorectal cancer. Using a cohort design, 257,623 children from The Copenhagen School Health Records Register born from 1930 to 1972 with measured heights and weights at ages 7 to 13 years were followed for adult colon and rectal adenocarcinomas by linkage to the Danish Cancer Registry. Hazard ratios (HRs) with 95% confidence intervals (CI) were estimated by Cox proportional hazard regressions...
August 12, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28801584/differences-of-protein-expression-profiles-kras-and-braf-mutation-and-prognosis-in-right-sided-colon-left-sided-colon-and-rectal-cancer
#6
Xian Hua Gao, Guan Yu Yu, Hai Feng Gong, Lian Jie Liu, Yi Xu, Li Qiang Hao, Peng Liu, Zhi Hong Liu, Chen Guang Bai, Wei Zhang
To compare protein expression levels, gene mutation and survival among Right-Sided Colon Cancer (RSCC), Left-Sided Colon Cancer (LSCC) and rectal cancer patients, 57 cases of RSCC, 87 LSCC and 145 rectal cancer patients were included retrospectively. Our results demonstrated significant differences existed among RSCC, LSCC and rectal cancer regarding tumor diameter, differentiation, invasion depth and TNM stage. No significant difference was identified in expression levels of MLH1, MSH2, MSH6, PMS2, β-Tubulin III, P53, Ki67 and TOPIIα, and gene mutation of KRAS and BRAF among three groups...
August 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28799112/the-dgav-risk-calculator-development-and-validation-of-statistical-models-for-a-web-based-instrument-predicting-complications-of-colorectal-cancer-surgery
#7
Alexander Crispin, Carsten Klinger, Anna Rieger, Brigitte Strahwald, Kai Lehmann, Heinz-Johannes Buhr, Ulrich Mansmann
PURPOSE: The purpose of this study is to provide a web-based calculator predicting complication probabilities of patients undergoing colorectal cancer (CRC) surgery in Germany. METHODS: Analyses were based on records of first-time CRC surgery between 2010 and February 2017, documented in the database of the Study, Documentation, and Quality Center (StuDoQ) of the Deutsche Gesellschaft für Allgemein- und Viszeralchirurgie (DGAV), a registry of CRC surgery in hospitals throughout Germany, covering demography, medical history, tumor features, comorbidity, behavioral risk factors, surgical procedures, and outcomes...
August 10, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28799061/transrectal-rigid-hybrid-notes-cholecystectomy-can-be-performed-without-peritoneal-contamination-a-controlled-porcine-survival-study
#8
Philip C Müller, Jonas D Senft, Philip Gath, Daniel C Steinemann, Felix Nickel, Adrian T Billeter, Beat P Müller-Stich, Georg R Linke
BACKGROUND AND STUDY AIMS: The risk of infectious complications due to peritoneal contamination is a major concern and inhibits the widespread use of transrectal NOTES. A standardized rectal washout with a reversible colon occlusion device in situ has previously shown potential in reducing peritoneal contamination. The aim of this study was to compare the peritoneal contamination rate and inflammatory reaction for transrectal cholecystectomy after ideal rectal preparation (trCCE) and standard laparoscopic cholecystectomy (lapCCE) in a porcine survival experiment...
August 10, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28798942/transient-descending-colocolonic-intussusception-due-to-a-large-fecaloma-in-an-adult
#9
Zubair Khan, Umar Darr, Anas Renno, Turki Alkully, Ehsan Rafiq, Thomas Sodeman
Intussusception typically occurs in infants and children, with adults representing 5% of cases. A 53-year-old African American woman presented with lower abdominal pain and tenderness. Computed tomography of the abdomen and pelvis demonstrated a 3.5 cm colocolonic intussusception in the descending colon. Emergent colonoscopy found solid stool in the mid descending colon. Water-soluble rectal enema showed a filling defect in the mid descending colon. Repeat colonoscopy demonstrated presence of a large fecaloma in left colon...
2017: ACG Case Reports Journal
https://www.readbyqxmd.com/read/28798242/a-rare-urological-presentation-of-appendicitis
#10
Nick Simson, Thomas Stonier, Alberto Coscione, Ahmed Qteishat
A 17-year-old boy with no medical comorbidities, but a significant family history of malignancy, presented to Accident and Emergency following 3 days of increasing rectal pain, symptoms of bladder outflow obstruction (poor flow, intermittent stream and hesitancy) and dysuria. Notably he had no abdominal pain. Digital rectal examination revealed a tender, enlarged prostate. Inflammatory markers were significantly raised (white cell count 17.7, C reactive protein 191). He was diagnosed clinically as prostatitis and commenced on intravenous antibiotics...
August 10, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28797098/comparative-genomics-of-two-super-shedder-isolates-of-escherichia-coli-o157-h7
#11
Robab Katani, Rebecca Cote, Indira T Kudva, Chitrita DebRoy, Terrance M Arthur, Vivek Kapur
Shiga toxin-producing Escherichia coli O157:H7 (O157) are zoonotic foodborne pathogens and of major public health concern that cause considerable intestinal and extra-intestinal illnesses in humans. O157 colonize the recto-anal junction (RAJ) of asymptomatic cattle who shed the bacterium into the environment through fecal matter. A small subset of cattle, termed super-shedders (SS), excrete O157 at a rate (≥ 104 CFU/g of feces) that is several orders of magnitude greater than other colonized cattle and play a major role in the prevalence and transmission of O157...
2017: PloS One
https://www.readbyqxmd.com/read/28796745/colon-and-rectal-surgery-regional-society-meetings
#12
(no author information available yet)
No abstract text is available yet for this article.
September 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28796744/residency-programs-in-colon-and-rectal-surgery
#13
(no author information available yet)
No abstract text is available yet for this article.
September 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28796726/the-american-society-of-colon-and-rectal-surgeons-clinical-practice-guidelines-for-the-management-of-inherited-polyposis-syndromes
#14
Daniel Herzig, Karin Hardimann, Martin Weiser, Nancy Yu, Ian Paquette, Daniel L Feingold, Scott R Steele
No abstract text is available yet for this article.
September 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28796725/what-every-colorectal-surgeon-should-know-about-the-medicare-access-and-children-s-health-insurance-program-reauthorization-act-of-2015
#15
Walter R Peters, Don Colvin, Jeff Cohen
No abstract text is available yet for this article.
September 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28795369/trace-element-and-heavy-metal-levels-in-colorectal-cancer-comparison-between-cancerous-and-non-cancerous-tissues
#16
Masoudreza Sohrabi, Ali Gholami, MohammadHossein Hosseini Azar, Mohammad Yaghoobi, Maryamosadat Mirasgari Shahi, Solmaz Shirmardi, Mehdi Nikkhah, Zahra Kohi, Delaram Salehpour, Mahmood Reza Khoonsari, Gholamrez Hemmasi, Farhad Zamani, Mahmoudreza Sohrabi, Hossein Ajdarkosh
Cases of colorectal cancer (CRC) have increased dramatically in Middle Eastern and other Asian countries. Many studies indicate an important role of environmental factors, including trace elements as an etiology of cancer. This study aims to assess the concentration of eight trace elements in cancerous and adjacent non-cancerous tissues in case of CRC. In a cross-sectional study, conducted between March 2015 and February 2016, zinc (Zn), chromium (Cr), manganese (Mn), tin (Sn), copper (Cu), aluminum (Al), lead (Pb), and iron (Fe) levels were evaluated among patients suffering from CRC...
August 9, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28792013/a-summary-of-meat-intakes-and-health-burdens
#17
REVIEW
C S C Yip, W Lam, R Fielding
This review summarizes published meta-analysis outcomes on the associations between meat intakes and burden of diseases. A novel assessment process was developed, combining selected Cochrane Review measures, AMSTAR checklist, and other quality measures identified by authors during preliminary phases of the review process. Meat intakes have been found to be statistically significant associated with 21 burden of diseases. A total of 37 risk-outcome best dose-response estimations were identified, all were positively associated, and 21 of them with low to moderate, or insignificant heterogeneity...
August 9, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28776285/clinical-practice-guideline-for-enhanced-recovery-after-colon-and-rectal-surgery-from-the-american-society-of-colon-and-rectal-surgeons-ascrs-and-society-of-american-gastrointestinal-and-endoscopic-surgeons-sages
#18
Joseph C Carmichael, Deborah S Keller, Gabriele Baldini, Liliana Bordeianou, Eric Weiss, Lawrence Lee, Marylise Boutros, James McClane, Scott R Steele, Liane S Feldman
No abstract text is available yet for this article.
August 3, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28770123/prevention-of-histological-changes-after-colonic-diversion-in-rats-an-experimental-study
#19
Pathak M, Srinivas M, Shariff A
AIM: To determine the beneficial effects of Glutamine, Psyllium, Short Chain Fatty Acids (SCFA), and Maharishi Amrit Kalash (MAK), in preventing the histological changes after diversion colostomy. MATERIAL AND METHODS: After ethical clearance, male wistar rats (n=40) underwent diversion colostomy. Rats were divided into five groups of 8 rats each. Each group was given, after diversion colostomy, per rectally, one of the five agents being tested as an enema (3 ml/kg/day)...
April 2017: Journal of Neonatal Surgery
https://www.readbyqxmd.com/read/28770104/immunoscore-in-mismatch-repair-proficient-and-deficient-colon-cancer
#20
Erkki-Ville Wirta, Toni Seppälä, Marjukka Friman, Juha Väyrynen, Maarit Ahtiainen, Hannu Kautiainen, Teijo Kuopio, Ilmo Kellokumpu, Jukka-Pekka Mecklin, Jan Böhm
The aim of this study was to investigate immune response and its prognostic significance in colon carcinomas using the previously described Immunoscore (IS). A population-based series of 779 colorectal cancers, operated on between 2000 and 2010, were classified according to tumour, node, metastasis (TNM) status, mismatch repair (MMR), and BRAF mutation status. Rectal cancer cases (n = 203) were excluded as a high proportion of these patients received preoperative neoadjuvant chemoradiotherapy. Tissue microarray (TMA) samples collected from the tumour centre and invasive front were immunostained for CD3 and CD8...
July 2017: Journal of Pathology. Clinical Research
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