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Lichen plan

Rimesh Pal, Ashu Rastogi, Santosh Kumar, Anil Bhansali
A 45-year-old woman was diagnosed as having multiple endocrine neoplasia type 2A in 2014. She had bilateral pheochromocytoma, medullary thyroid carcinoma and biopsy-proven cutaneous lichen amyloidosis in the interscapular area. She underwent bilateral adrenalectomy; following which, she achieved clinical and biochemical remission. She was planned for total thyroidectomy at a later date; however, she was lost to follow-up. She presented to us again in December 2016 with abdominal pain. Examination revealed hypertension with postural drop...
March 28, 2018: BMJ Case Reports
Toby Spribille
The term symbiosis was first used in biology to describe the 'living together' of fungi and algae in lichens. For much of the 20th century, the fungal partner was assumed to be invested with the ability to produce the lichen body plan in presence of a photosynthesizing partner. However, studies of fungal evolution have uncovered discordance between lichen symbiotic outcomes and genome evolution of the fungus. At the same time, evidence has emerged that the structurally important lichen cortex contains lichen-specific, single-celled microbes, suggesting it may function like a biofilm...
March 9, 2018: Current Opinion in Plant Biology
Carol Emi Bretschneider, Sarah M Share, Marie Fidela R Paraiso
BACKGROUND: Severe labial agglutination can be refractory to outpatient management and can lead to voiding dysfunction in postmenopausal women. Labial agglutination is often a sequela of long-standing inflammatory processes, which include untreated lichen planus, lichen sclerosus, and atrophic vaginitis. CASE: An 82-year-old parous woman presented with severe labial agglutination and complete obstruction of her vaginal introitus, causing obstructive voiding symptoms...
February 27, 2018: Female Pelvic Medicine & Reconstructive Surgery
Frances S Dunn, Alexander G Liu, Philip C J Donoghue
Rocks of the Ediacaran System (635-541 Ma) preserve fossil evidence of some of the earliest complex macroscopic organisms, many of which have been interpreted as animals. However, the unusual morphologies of some of these organisms have made it difficult to resolve their biological relationships to modern metazoan groups. Alternative competing phylogenetic interpretations have been proposed for Ediacaran taxa, including algae, fungi, lichens, rhizoid protists, and even an extinct higher-order group (Vendobionta)...
November 3, 2017: Biological Reviews of the Cambridge Philosophical Society
Joana Vieira, Paula Matos, Teresa Mexia, Patrícia Silva, Nuno Lopes, Catarina Freitas, Otília Correia, Margarida Santos-Reis, Cristina Branquinho, Pedro Pinho
The growing human population concentrated in urban areas lead to the increase of road traffic and artificial areas, consequently enhancing air pollution and urban heat island effects, among others. These environmental changes affect citizen's health, causing a high number of premature deaths, with considerable social and economic costs. Nature-based solutions are essential to ameliorate those impacts in urban areas. While the mere presence of urban green spaces is pointed as an overarching solution, the relative importance of specific vegetation structure, composition and management to improve the ecosystem services of air purification and climate regulation are overlooked...
January 2018: Environmental Research
Lajevardi Vahide, Halaji Zahra, Ghaedi Forugh, Saljoughi Nazi
There is controversy about the role of autoantibodies against desmoglein 1 and 3 (Dsg1 and 3) in the pathogenesis of lichen planus (LP); the authors planned this study to determine the presence of circulating levels of these antibodies in patients with different types of oral LP and to compare that with cutaneous LP and healthy controls. The enzyme-linked immunosorbent assay test was performed on serum samples of 24 cases of erosive oral LP, 29 cases of reticular oral LP, 30 cases of cutaneous LP and 30 healthy controls...
September 2017: Archives of Dermatological Research
Kumud Mittal, Mihir Jha, Roopa S Patil, Shekhar Kapoor
Lichenoid Dysplasia (LD) is often regarded as lichen planus with dysplastic features, as it mimics lichen planus clinically and histologically. Although it has been confirmed that these two entities are entirely different with not so similar etiopathogenesis, yet the confusion still exists. The separation between the two is of utmost importance as each of them has their own prognosis and treatment plan. We report one such case, where a 51-year-old male with excessive burning sensation had similar clinical picture as that of lichen planus but was histologically diagnosed as LD...
May 2017: Journal of Clinical and Diagnostic Research: JCDR
Gillian A Hirth, Mathew P Johansen, Julia G Carpenter, Andreas Bollhöfer, Nicholas A Beresford
Wildlife concentration ratios for (226)Ra, (210)Pb, (210)Po and isotopes of Th and U from soil, water, and sediments were evaluated for a range of Australian uranium mining environments. Whole-organism concentration ratios (CRwo-media) were developed for 271 radionuclide-organism pairs within the terrestrial and freshwater wildlife groups. Australian wildlife often has distinct physiological attributes, such as the lower metabolic rates of macropod marsupials as compared with placental mammals. In addition, the Australian CRswo-media originate from tropical and semi-arid climates, rather than from the temperate-dominated climates of Europe and North America from which most (>90%) of internationally available CRwo-media values originate...
November 2017: Journal of Environmental Radioactivity
Jiao Wei, Danhua Ma, Min Qiu, Hongxia Dan, Xin Zeng, Lu Jiang, Yu Zhou, Jiayi Wang, Qianming Chen
Oral lichen planus (OLP) is a common chronic inflammatory disorder that manifests as papular, reticular, or erosive lesions. OLP seriously affects a patient's quality of life, as it is associated with symptoms such as pain and a burning sensation. It is also accompanied by a risk of carcinogenic tendency. During pregnancy, the treatment will be more complicated because of the effect of medical treatment on both the mother and foetus. Thus, appropriate drugs for those pregnant patients will be more essential...
January 2017: Acta Odontologica Scandinavica
Lindsay P Chiquoine, Scott R Abella, Matthew A Bowker
Restoring biological soil crusts (biocrusts) in degraded drylands can contribute to recovery of ecosystem functions that have global implications, including erosion resistance and nutrient cycling. To examine techniques for restoring biocrusts, we conducted a replicated, factorial experiment on recently abandoned road surfaces by applying biocrust inoculation (salvaged and stored dry for two years), salvaged topsoil, an abiotic soil amendment (wood shavings), and planting of a dominant perennial shrub (Ambrosia dumosa)...
June 2016: Ecological Applications: a Publication of the Ecological Society of America
Helena Tukiainen, Joseph J Bailey, Richard Field, Katja Kangas, Jan Hjort
Understanding threatened species diversity is important for long-term conservation planning. Geodiversity-the diversity of Earth surface materials, forms, and processes-may be a useful biodiversity surrogate for conservation and have conservation value itself. Geodiversity and species richness relationships have been demonstrated; establishing whether geodiversity relates to threatened species' diversity and distribution pattern is a logical next step for conservation. We used 4 geodiversity variables (rock-type and soil-type richness, geomorphological diversity, and hydrological feature diversity) and 4 climatic and topographic variables to model threatened species diversity across 31 of Finland's national parks...
April 2017: Conservation Biology: the Journal of the Society for Conservation Biology
Kurt A Ashack, Laura L Haley, Chelsea A Luther, Christie A Riemer, Richard J Ashack
BACKGROUND: Mucosal lichen planus (MLP) is a therapeutic challenge in need of a new treatment approach because of its debilitating effect on patient's quality of life. OBJECTIVE: We sought to evaluate a standardized treatment plan for patients with MLP. A second objective was to describe the effect of mycophenolate mofetil in this patient population. METHODS: The study retrospectively analyzed 53 patients with MLP treated using a standardized algorithm...
June 2016: Journal of the American Academy of Dermatology
Kelly R Stiegel, Eman Bahrani, Ramsey F Markus
Postoperative complications present in many forms and can cause great morbidity and even mortality in patients who experience them. Frey syndrome is an example of a postoperative complication in which aberrant nerve regeneration following parotidectomy leads to hyperhidrosis induced by gustatory stimuli. We present a unique but similar case of aberrant nerve regeneration and resulting hypersecretion that emerged 6-7 months following perineoplasty and labial reduction for lichen sclerosus in a 53-year-old woman...
March 16, 2016: Dermatology Online Journal
Chintan K Patel, Jill C Buckley, Leonard N Zinman, Alex J Vanni
OBJECTIVE: To evaluate the intermediate-term outcomes from a large, single institution series of patients with lichen sclerosus (LS) who underwent surgical management of their urethral strictures. MATERIALS AND METHODS: We retrospectively reviewed 79 patients who underwent surgical management of their LS urethral strictures from 2003 to 2014, comparing outcomes of patients undergoing a single-stage buccal mucosa graft (BMG) urethroplasty, 2-stage BMG urethroplasty, or perineal urethrostomy (PU)...
May 2016: Urology
Lokman Irkilata, Mustafa Bakirtas, Hasan Riza Aydin, Mustafa Aydin, H Uuml Seyin Cihan Demirel, Senol Adanur, Caner Moral, Mustafa Kemal Atilla
OBJECTIVE: To evaluate histopathological results of foreskin removed during circumcision in the pediatric age group and the relationship between these and the degree of phimosis. STUDY DESIGN: Cross-sectional study. PLACE AND DURATION OF STUDY: Department of Urology, Samsun Training and Research Hospital, Samsun, Turkey, from June to December 2014. METHODOLOGY: Male children undergoing planned circumcision were examined for the presence and degree of phimosis which was recorded before the operation...
February 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
Bradley A Potts, Michael J Belsante, Andrew C Peterson
PURPOSE: We investigated outcomes of the contemporary practice of administering intraurethral steroids to treat stricture disease in patients with biopsy proven lichen sclerosus. MATERIALS AND METHODS: We performed an institutional review board approved review of the records of patients with biopsy proven lichen sclerosus stricture disease from October 2010 to September 2015. Study inclusion criteria were age 18 years or greater and male gender. Extracted data included patient demographics, comorbidities, location of lichen sclerosus, previous therapies and need for further interventions...
June 2016: Journal of Urology
Angela C Telfer, Monica R Young, Jenna Quinn, Kate Perez, Crystal N Sobel, Jayme E Sones, Valerie Levesque-Beaudin, Rachael Derbyshire, Jose Fernandez-Triana, Rodolphe Rougerie, Abinah Thevanayagam, Adrian Boskovic, Alex V Borisenko, Alex Cadel, Allison Brown, Anais Pages, Anibal H Castillo, Annegret Nicolai, Barb Mockford Glenn Mockford, Belén Bukowski, Bill Wilson, Brock Trojahn, Carole Ann Lacroix, Chris Brimblecombe, Christoper Hay, Christmas Ho, Claudia Steinke, Connor P Warne, Cristina Garrido Cortes, Daniel Engelking, Danielle Wright, Dario A Lijtmaer, David Gascoigne, David Hernandez Martich, Derek Morningstar, Dirk Neumann, Dirk Steinke, Donna DeBruin Marco DeBruin, Dylan Dobias, Elizabeth Sears, Ellen Richard, Emily Damstra, Evgeny V Zakharov, Frederic Laberge, Gemma E Collins, Gergin A Blagoev, Gerrie Grainge, Graham Ansell, Greg Meredith, Ian Hogg, Jaclyn McKeown, Janet Topan, Jason Bracey, Jerry Guenther, Jesse Sills-Gilligan, Joseph Addesi, Joshua Persi, Kara K S Layton, Kareina D'Souza, Kencho Dorji, Kevin Grundy, Kirsti Nghidinwa, Kylee Ronnenberg, Kyung Min Lee, Linxi Xie, Liuqiong Lu, Lyubomir Penev, Mailyn Gonzalez, Margaret E Rosati, Mari Kekkonen, Maria Kuzmina, Marianne Iskandar, Marko Mutanen, Maryam Fatahi, Mikko Pentinsaari, Miriam Bauman, Nadya Nikolova, Natalia V Ivanova, Nathaniel Jones, Nimalka Weerasuriya, Norman Monkhouse, Pablo D Lavinia, Paul Jannetta, Priscila E Hanisch, R Troy McMullin, Rafael Ojeda Flores, Raphaëlle Mouttet, Reid Vender, Renee N Labbee, Robert Forsyth, Rob Lauder, Ross Dickson, Ruth Kroft, Scott E Miller, Shannon MacDonald, Sishir Panthi, Stephanie Pedersen, Stephanie Sobek-Swant, Suresh Naik, Tatsiana Lipinskaya, Thanushi Eagalle, Thibaud Decaëns, Thibault Kosuth, Thomas Braukmann, Tom Woodcock, Tomas Roslin, Tony Zammit, Victoria Campbell, Vlad Dinca, Vlada Peneva, Paul D N Hebert, Jeremy R deWaard
BACKGROUND: Comprehensive biotic surveys, or 'all taxon biodiversity inventories' (ATBI), have traditionally been limited in scale or scope due to the complications surrounding specimen sorting and species identification. To circumvent these issues, several ATBI projects have successfully integrated DNA barcoding into their identification procedures and witnessed acceleration in their surveys and subsequent increase in project scope and scale. The Biodiversity Institute of Ontario partnered with the rare Charitable Research Reserve and delegates of the 6th International Barcode of Life Conference to complete its own rapid, barcode-assisted ATBI of an established land trust in Cambridge, Ontario, Canada...
2015: Biodiversity Data Journal
Monica Enamandram, James P Rathmell, Alexandra B Kimball
A number of chronic dermatologic conditions may necessitate long-term adjunctive pain management in addition to treatment of the primary skin disease, such as hidradenitis suppurativa, lichen planus, and other systemic diseases associated with significant pain. Adequate management of chronic pain can represent a unique challenge, but remains an integral component of clinical treatment in relevant contexts. For nociceptive pain of moderate to severe intensity, opioid analgesics can be beneficial when other pain management strategies have failed to produce adequate relief...
October 2015: Journal of the American Academy of Dermatology
Sudha Jimson, N Balachader, N Anita, R Babu
Immune mediated diseases of oral cavity are uncommon. The lesions may be self-limiting and undergo remission spontaneously. Among the immune mediated oral lesions the most important are lichen planus, pemphigus, erythema multiformi, epidermolysis bullosa, systemic lupus erythematosis. Cellular and humoral mediated immunity play a major role directed against epithelial and connective tissue in chronic and recurrent patterns. Confirmatory diagnosis can be made by biopsy, direct and indirect immunoflouresence, immune precipitation and immunoblotting...
April 2015: Journal of Pharmacy & Bioallied Sciences
Neena S Sawant, Nakul A Vanjari, Uday Khopkar, Satish Adulkar
The precise cause of lichen planus is unknown, but the disease seems to be immunologically mediated. It is a psychocutaneous disorder. Due to scarcity of Indian studies in this field, we decided to study in patients of lichen planus the prevalence of depression and quality of life with comparison of the same in both the genders. Patients diagnosed as having lichen planus by consultant dermatologist were enrolled after informed consent and ethics approval. 45 patients were screened, of which 35 who satisfied the criteria were taken up for the study...
2015: TheScientificWorldJournal
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