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Lichen plan

Jiao Wei, Danhua Ma, Min Qiu, Hongxia Dan, Xin Zeng, Lu Jiang, Yu Zhou, Jiayi Wang, Qianming Chen
Oral lichen planus (OLP) is a common chronic inflammatory disorder that manifests as papular, reticular, or erosive lesions. OLP seriously affects a patient's quality of life, as it is associated with symptoms such as pain and a burning sensation. It is also accompanied by a risk of carcinogenic tendency. During pregnancy, the treatment will be more complicated because of the effect of medical treatment on both the mother and foetus. Thus, appropriate drugs for those pregnant patients will be more essential...
January 2017: Acta Odontologica Scandinavica
Lindsay P Chiquoine, Scott R Abella, Matthew A Bowker
Restoring biological soil crusts (biocrusts) in degraded drylands can contribute to recovery of ecosystem functions that have global implications, including erosion resistance and nutrient cycling. To examine techniques for restoring biocrusts, we conducted a replicated, factorial experiment on recently abandoned road surfaces by applying biocrust inoculation (salvaged and stored dry for two years), salvaged topsoil, an abiotic soil amendment (wood shavings), and planting of a dominant perennial shrub (Ambrosia dumosa)...
June 2016: Ecological Applications: a Publication of the Ecological Society of America
Helena Tukiainen, Joseph J Bailey, Richard Field, Katja Kangas, Jan Hjort
Improved understanding of threatened species diversity is important for long-term conservation planning and natural area management, especially under ongoing global change. Geodiversity - the diversity of earth surface materials, forms and processes - may be a useful biodiversity surrogate for conservation planning, as well as having conservation value itself. Links between geodiversity and species richness have been demonstrated; establishing whether geodiversity also relates to threatened species' diversity and distribution patterns is a logical next step for conservation biology...
August 1, 2016: Conservation Biology: the Journal of the Society for Conservation Biology
Kurt A Ashack, Laura L Haley, Chelsea A Luther, Christie A Riemer, Richard J Ashack
BACKGROUND: Mucosal lichen planus (MLP) is a therapeutic challenge in need of a new treatment approach because of its debilitating effect on patient's quality of life. OBJECTIVE: We sought to evaluate a standardized treatment plan for patients with MLP. A second objective was to describe the effect of mycophenolate mofetil in this patient population. METHODS: The study retrospectively analyzed 53 patients with MLP treated using a standardized algorithm...
June 2016: Journal of the American Academy of Dermatology
Kelly R Stiegel, Eman Bahrani, Ramsey F Markus
Postoperative complications present in many forms and can cause great morbidity and even mortality in patients who experience them. Frey syndrome is an example of a postoperative complication in which aberrant nerve regeneration following parotidectomy leads to hyperhidrosis induced by gustatory stimuli. We present a unique but similar case of aberrant nerve regeneration and resulting hypersecretion that emerged 6-7 months following perineoplasty and labial reduction for lichen sclerosus in a 53-year-old woman...
March 16, 2016: Dermatology Online Journal
Chintan K Patel, Jill C Buckley, Leonard N Zinman, Alex J Vanni
OBJECTIVE: To evaluate the intermediate-term outcomes from a large, single institution series of patients with lichen sclerosus (LS) who underwent surgical management of their urethral strictures. MATERIALS AND METHODS: We retrospectively reviewed 79 patients who underwent surgical management of their LS urethral strictures from 2003 to 2014, comparing outcomes of patients undergoing a single-stage buccal mucosa graft (BMG) urethroplasty, 2-stage BMG urethroplasty, or perineal urethrostomy (PU)...
May 2016: Urology
Lokman Irkilata, Mustafa Bakirtas, Hasan Riza Aydin, Mustafa Aydin, H Uuml Seyin Cihan Demirel, Senol Adanur, Caner Moral, Mustafa Kemal Atilla
OBJECTIVE: To evaluate histopathological results of foreskin removed during circumcision in the pediatric age group and the relationship between these and the degree of phimosis. STUDY DESIGN: Cross-sectional study. PLACE AND DURATION OF STUDY: Department of Urology, Samsun Training and Research Hospital, Samsun, Turkey, from June to December 2014. METHODOLOGY: Male children undergoing planned circumcision were examined for the presence and degree of phimosis which was recorded before the operation...
February 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
Bradley A Potts, Michael J Belsante, Andrew C Peterson
PURPOSE: We investigated outcomes of the contemporary practice of administering intraurethral steroids to treat stricture disease in patients with biopsy proven lichen sclerosus. MATERIALS AND METHODS: We performed an institutional review board approved review of the records of patients with biopsy proven lichen sclerosus stricture disease from October 2010 to September 2015. Study inclusion criteria were age 18 years or greater and male gender. Extracted data included patient demographics, comorbidities, location of lichen sclerosus, previous therapies and need for further interventions...
June 2016: Journal of Urology
Angela C Telfer, Monica R Young, Jenna Quinn, Kate Perez, Crystal N Sobel, Jayme E Sones, Valerie Levesque-Beaudin, Rachael Derbyshire, Jose Fernandez-Triana, Rodolphe Rougerie, Abinah Thevanayagam, Adrian Boskovic, Alex V Borisenko, Alex Cadel, Allison Brown, Anais Pages, Anibal H Castillo, Annegret Nicolai, Barb Mockford Glenn Mockford, Belén Bukowski, Bill Wilson, Brock Trojahn, Carole Ann Lacroix, Chris Brimblecombe, Christoper Hay, Christmas Ho, Claudia Steinke, Connor P Warne, Cristina Garrido Cortes, Daniel Engelking, Danielle Wright, Dario A Lijtmaer, David Gascoigne, David Hernandez Martich, Derek Morningstar, Dirk Neumann, Dirk Steinke, Donna DeBruin Marco DeBruin, Dylan Dobias, Elizabeth Sears, Ellen Richard, Emily Damstra, Evgeny V Zakharov, Frederic Laberge, Gemma E Collins, Gergin A Blagoev, Gerrie Grainge, Graham Ansell, Greg Meredith, Ian Hogg, Jaclyn McKeown, Janet Topan, Jason Bracey, Jerry Guenther, Jesse Sills-Gilligan, Joseph Addesi, Joshua Persi, Kara K S Layton, Kareina D'Souza, Kencho Dorji, Kevin Grundy, Kirsti Nghidinwa, Kylee Ronnenberg, Kyung Min Lee, Linxi Xie, Liuqiong Lu, Lyubomir Penev, Mailyn Gonzalez, Margaret E Rosati, Mari Kekkonen, Maria Kuzmina, Marianne Iskandar, Marko Mutanen, Maryam Fatahi, Mikko Pentinsaari, Miriam Bauman, Nadya Nikolova, Natalia V Ivanova, Nathaniel Jones, Nimalka Weerasuriya, Norman Monkhouse, Pablo D Lavinia, Paul Jannetta, Priscila E Hanisch, R Troy McMullin, Rafael Ojeda Flores, Raphaëlle Mouttet, Reid Vender, Renee N Labbee, Robert Forsyth, Rob Lauder, Ross Dickson, Ruth Kroft, Scott E Miller, Shannon MacDonald, Sishir Panthi, Stephanie Pedersen, Stephanie Sobek-Swant, Suresh Naik, Tatsiana Lipinskaya, Thanushi Eagalle, Thibaud Decaëns, Thibault Kosuth, Thomas Braukmann, Tom Woodcock, Tomas Roslin, Tony Zammit, Victoria Campbell, Vlad Dinca, Vlada Peneva, Paul D N Hebert, Jeremy R deWaard
BACKGROUND: Comprehensive biotic surveys, or 'all taxon biodiversity inventories' (ATBI), have traditionally been limited in scale or scope due to the complications surrounding specimen sorting and species identification. To circumvent these issues, several ATBI projects have successfully integrated DNA barcoding into their identification procedures and witnessed acceleration in their surveys and subsequent increase in project scope and scale. The Biodiversity Institute of Ontario partnered with the rare Charitable Research Reserve and delegates of the 6th International Barcode of Life Conference to complete its own rapid, barcode-assisted ATBI of an established land trust in Cambridge, Ontario, Canada...
2015: Biodiversity Data Journal
Monica Enamandram, James P Rathmell, Alexandra B Kimball
A number of chronic dermatologic conditions may necessitate long-term adjunctive pain management in addition to treatment of the primary skin disease, such as hidradenitis suppurativa, lichen planus, and other systemic diseases associated with significant pain. Adequate management of chronic pain can represent a unique challenge, but remains an integral component of clinical treatment in relevant contexts. For nociceptive pain of moderate to severe intensity, opioid analgesics can be beneficial when other pain management strategies have failed to produce adequate relief...
October 2015: Journal of the American Academy of Dermatology
Sudha Jimson, N Balachader, N Anita, R Babu
Immune mediated diseases of oral cavity are uncommon. The lesions may be self-limiting and undergo remission spontaneously. Among the immune mediated oral lesions the most important are lichen planus, pemphigus, erythema multiformi, epidermolysis bullosa, systemic lupus erythematosis. Cellular and humoral mediated immunity play a major role directed against epithelial and connective tissue in chronic and recurrent patterns. Confirmatory diagnosis can be made by biopsy, direct and indirect immunoflouresence, immune precipitation and immunoblotting...
April 2015: Journal of Pharmacy & Bioallied Sciences
Neena S Sawant, Nakul A Vanjari, Uday Khopkar, Satish Adulkar
The precise cause of lichen planus is unknown, but the disease seems to be immunologically mediated. It is a psychocutaneous disorder. Due to scarcity of Indian studies in this field, we decided to study in patients of lichen planus the prevalence of depression and quality of life with comparison of the same in both the genders. Patients diagnosed as having lichen planus by consultant dermatologist were enrolled after informed consent and ethics approval. 45 patients were screened, of which 35 who satisfied the criteria were taken up for the study...
2015: TheScientificWorldJournal
Jörgen Rudolphi, Mari T Jönsson, Lena Gustafsson, H Bugmann
Clearcutting has been identified as a main threat to forest biodiversity. In the last few decades, alternatives to clearcutting have gained much interest. Living and dead trees are often retained after harvest to serve as structural legacies to mitigate negative effects of forestry. However, this practice is widely employed without information from systematic before-after control-impact studies to assess the processes involved in species responses after clearcutting with retention. We performed a large-scale survey of the occurrence of logging-sensitive and red-listed bryophytes and lichens before and after clearcutting with the retention approach...
February 2014: Journal of Applied Ecology
Carmen Gheorghe, Lelia Mihai, Ioanina Parlatescu, Serban Tovaru
The relationship between chronic hepatitis C virus infection (HCV) and oral lichen planus (OLP) is a current topic in the field of oral medicine. Many studies of this association have been made over time. The geographic variation of the hepatitis C prevalence proved to be an important factor influencing the statistical results of the studies analyzing the association of the oral plan lichen with the hepatitis C virus. Approaching this issue is not to be neglected. Treatment outcomes in patients with oral lichen planus associated with chronic hepatitis C virus are often unsatisfactory compared to patients suffering from idiopathic oral lichen planus...
March 2014: Mædica
Marinka Mravak-Stipetić, Božana Lončar-Brzak, Iva Bakale-Hodak, Ivan Sabol, Sven Seiwerth, Martina Majstorović, Magdalena Grce
Oral lichen planus (OLP) and oral lichenoid lesions (OLL) are clinically and histologically similar lesions but their treatment planning and prognosis are different. The review of the literature indicates numerous criteria to distinguish these two lesions; however there is a lot of inconsistency. Thus, the aim of this study was to determine the correlation of histopathology and clinical OLP and OLL diagnosis and to clarify which histopathologic criteria could best distinguish these two diagnoses. A retrospective study showed that clinically diagnosed 92 OLPs and 14 OLLs have been confirmed histopathologically in 52...
2014: TheScientificWorldJournal
Mairim Russo Serafini, Cassia Britto Detoni, Sílvia Stanisçuaski Guterres, Gabriel Francisco da Silva, Adriano Antunes de Souza Araújo
Usnic acid, a lichen metabolite, has been proposed as a potential topical treatment for microbial skin lesions, burn wounds as well as a sunscreen. An isocratic HPLC method was validated according to FDA's Guidance for Industry: Bioanalytical Method Validation to determine skin penetration and permeation of usnic acid. The penetration and permeation of usnic acid was evaluated using Franz cells and porcine skin. The method was valid according to selectivity, linearity, precision, accuracy and stability. Usnic acid was quantified in the skin surface (6...
May 2015: Journal of Chromatographic Science
Martin Leclerc, Christian Dussault, Martin-Hugues St-Laurent
Behavioural strategies may have important fitness, ecological and evolutionary consequences. In woodland caribou, human disturbances are associated with higher predation risk. Between 2004 and 2011, we investigated if habitat selection strategies of female caribou towards disturbances influenced their calf's survival in managed boreal forest with varying intensities of human disturbances. Calf survival was 53% and 43% after 30 and 90 days following birth, respectively, and 52% of calves that died were killed by black bear...
September 2014: Oecologia
Katarzyna Rajkowska, Anna Otlewska, Anna Koziróg, Małgorzata Piotrowska, Paulina Nowicka-Krawczyk, Mariusz Hachułka, Grzegorz J Wolski, Alina Kunicka-Styczyńska, Beata Gutarowska, Agnieszka Zydzik-Białek
The objective of this study was to assess biological colonization of wooden and brick buildings in the former Auschwitz II-Birkenau concentration camp, and to identify the organisms colonizing the examined buildings. Microbiological analysis did not reveal increased microbial activity, and the total microbial count of the barrack surfaces did not exceed 10(3) CFU/100 cm(2). However, certain symptoms of biodegradation of the buildings were observed. The predominant microflora consisted of bacteria of the genera Bacillus, Sporosarcina, Pseudomonas, Micrococcus, Streptomyces, and Staphylococcus, as well as fungi of the genera Acremonium, Cladosporium, Alternaria, Humicola, Penicillium, and Chaetomium...
2014: Annals of Microbiology
Alison Olcott Marshall, Craig P Marshall
Raman spectrometers are being miniaturized for future life-detection missions on Mars. Field-portable Raman spectrometers, which have similar spectral parameters to the instruments being developed for Mars rovers, have been used to examine extant biosignatures, but they have not yet been used to examine ancient biosignatures. Here, a portable Raman spectrometer was used to analyze an Ordovician stromatolite at the outcrop, revealing both its mineralogy and the presence of sp² carbonaceous material. As stromatolites are often used as proof of the presence of life in Archean rocks and are searched for on Mars, the ability to analyze them in the field with no sample preparation has important ramifications for future Mars missions...
September 2013: Astrobiology
Atousa Aminzadeh, Gholamreza Jahanshahi, Masoud Ahmadi
INTRODUCTION: Oral Lichen Planus (OLP) and Oral Lichenoid Lesions (OLLs) are clinically and histopathologically similar lesions but with different etiologies and treatment plan, thus differentiating these two has been the center of many researches. Studies in different populations have been performed on clinical and histopathologic features of OLP and OLLs. Thus aim of the present study was to evaluate and also compare the clinical and histopathologic features of these two diseases in a 10-year period in Esfahan...
March 2013: Dental Research Journal
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