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deep infiltrating endometriosis

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https://www.readbyqxmd.com/read/29132241/rectovaginal-fistula-following-surgery-for-deep-infiltrating-endometriosis-does-lesion-size-matter
#1
Yunxi Zheng, Ning Zhang, Weiqi Lu, Liang Zhang, Shouxin Gu, Ying Zhang, Xiaofang Yi, Keqin Hua
Objective This study was performed to identify risk factors for postoperative rectovaginal fistula (PRF) in patients with deep infiltrating endometriosis (DIE). Methods Data were retrospectively obtained from the medical records of 104 patients with DIE, and statistical analysis was used to detect risk factors for PRF. Results Five of 104 (4.8%) patients developed PRF from 5 to 16 days postoperatively. The operative procedures included 84 (80.8%) superficial excisions, 6 (5.8%) full-thickness disc excisions, and 14 (13...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/29129414/-surgical-management-of-deep-infiltrating-endometriosis-with-bowel-involvement-and-urinary-tract-involvement
#2
Sofiane Bendifallah, Marcos Ballester, Emile Darai
Endometriosis is a benign pathology that affects 3% of the general population and about 10% of women of reproductive age. Three anatomoclinical entities are described: peritoneal, ovarian (endometrioma) and deep endometriosis characterized by the infiltration of anatomical structures or organs beyond the peritoneum. Laparoscopic surgery should be performed, as this is associated with a reduction in postoperative complications, length of hospitalization and convalescence. Several surgical techniques allow the removal of deep endometriosis with colorectal involvement: rectal shaving, anterior discoid resection, segmental resection...
November 9, 2017: La Presse Médicale
https://www.readbyqxmd.com/read/29129409/-fertility-and-deep-infiltrating-endometriosis
#3
Jonathan Cohen, Emmanuelle Mathieu d'Argent, Lise Selleret, Jean-Marie Antoine, Nathalie Chabbert-Buffet, Sofiane Bendifallah, Marcos Ballester, Emile Darai
Deep infiltrating endometriosis is the most severe form of the disease, defined by infiltration beneath the peritoneum greater than 5mm. It affects several anatomical locations including the bladder, the vesico-uterine cul-de-sac, the torus uterinum, the uterosacral ligament, rectovaginal septum and the colon-rectum. Deep infiltrating endometriosis is associated with infertility. Surgery performed for deep infiltrating endometriosis in the context of pain offers good pregnancy rates either spontaneously or after assisted reproductive technologies...
November 9, 2017: La Presse Médicale
https://www.readbyqxmd.com/read/29126089/fertility-outcomes-after-laparoscopic-partial-bladder-resection-for-deep-endometriosis-retrospective-analysis-from-two-expert-centres-and-review-of-the-literature
#4
Krystel NyangohTimoh, Marcos Ballester, Sofiane Bendifallah, Arnaud Fauconnier, Emile Darai
OBJECTIVE: To evaluate fertility outcomes after laparoscopic partial bladder resection in women with bladder endometriosis and to review the literature. STUDY DESIGN: A retrospective study conducted at two tertiary referral centres -Tenon University Hospital and Poissy University Hospital (Canadian Task Force Classification Level II-2)-from July 2006 to November 2015. Patients with bladder endometriosis who underwent either laparoscopic partial bladder resection (PBR) alone for those without posterior endometriotic lesions (PBR group) or both laparoscopic PBR and associated posterior deep infiltrating endometriosis (DIE) resection (PBR-PDIE group) were included...
October 31, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29107715/differed-surgery-in-patient-with-colorectal-endometriosis-and-pregnancy-intention-is-it-reasonable
#5
S Touleimat, E Huet, S Sanguin, H Roman
The management of patients presenting deep infiltrating endometriosis involving the rectum (DIER) and pregnancy intention is controversial. Assisted Reproduction Techniques (ART) are often proposed first, but this may lead to complications and further difficulties managing DIER. A 29-years-old woman was diagnosed with pre-occlusive DIER. However, she was offered in vitro fertilization (IVF) and underwent six unsuccessful cycles with serious complications: an ectopic pregnancy and a hemoperitoneum following arterial injury during oocyte retrieval, requiring two laparotomies in emergency...
October 28, 2017: Journal of gynecology obstetrics and human reproduction
https://www.readbyqxmd.com/read/29100623/pathogenesis-of-deep-endometriosis
#6
REVIEW
Stephan Gordts, Philippe Koninckx, Ivo Brosens
The pathophysiology of (deep) endometriosis is still unclear. As originally suggested by Cullen, change the definition "deeper than 5 mm" to "adenomyosis externa." With the discovery of the old European literature on uterine bleeding in 5%-10% of the neonates and histologic evidence that the bleeding represents decidual shedding, it is postulated/hypothesized that endometrial stem/progenitor cells, implanted in the pelvic cavity after birth, may be at the origin of adolescent and even the occasionally premenarcheal pelvic endometriosis...
October 31, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/29097291/management-of-deep-infiltrating-endometriosis-of-the-rectum-is-a-systematic-temporary-stoma-relevant
#7
N Ledu, C Rubod, G Piessen, H Roman, P Collinet
STUDY OBJECTIVE: To assess the value of performing a protective stoma in patients operated for rectal endometriosis. MATERIAL AND METHODS: From June 2009 to December 2011, 47 patients were operated for rectal endometriosis by segmental or discoid resection in 4 different centers. Two groups were formed: one with protective stoma (group S), n=33 and one without protective stoma (group NS), n=14. Data were collected from the CIRENDO database. MEASUREMENTS AND MAIN RESULTS: Postoperative complication rate of group NS was 57% against 48% in group S (P=0...
October 31, 2017: Journal of gynecology obstetrics and human reproduction
https://www.readbyqxmd.com/read/29097234/patterns-of-bowel-invisible-microscopic-endometriosis-reveal-the-goal-of-surgery-removal-of-visual-lesions-only
#8
Alexandra Badescu, Horace Roman, Iulia Barsan, Valentin Soldea, Serban Nastasia, Moutaz Aziz, Lucian Puscasiu, Simona Stolnicu
STUDY OBJECTIVE: To document the presence of bowel invisible microscopic endometriosis implants and their relationship with deep endometriosis macronodule infiltrating the bowel. DESIGN: A series of consecutive patients with deep endometriosis infiltrating the rectum and/or sigmoid colon. DESIGN CLASSIFICATION: Canadian Task Force classification II-2. SETTINGS: University referral center. PATIENTS: Ten patients managed by colorectal resection...
October 30, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29080367/risk-of-bowel-obstruction-during-ivf-treatment-of-patients-with-deep-infiltrating-endometriosis
#9
Mikkel Seyer-Hansen, Anne Egekvist, Axel Forman, Mads Riiskjaer
INTRODUCTION: Women with endometriosis often experience pain and infertility. Medical treatment interferes with the possibility to attain pregnancy. For infertile women with endometriosis surgery is a possible treatment, but with advanced disease there is an increased risk of serious complications. With only limited pain, the women will often be referred for in vitro fertilization (IVF) treatment instead. The disease is estrogen dependant and during IVF treatment the women could theoretically experience worsening of their symptoms...
October 28, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29079275/endometriosis-especially-mild-disease-a-risk-factor-for-miscarriages
#10
MULTICENTER STUDY
Alexandra Sabrina Kohl Schwartz, Monika Martina Wölfler, Vera Mitter, Martina Rauchfuss, Felix Haeberlin, Markus Eberhard, Stephanie von Orelli, Bruno Imthurn, Patrick Imesch, Daniel Fink, Brigitte Leeners
OBJECTIVE: To investigate the prevalence of miscarriage in women with endometriosis (WwE) compared with disease-free control women (CW). DESIGN: Cross-sectional analysis nested in a retrospective observational study (n = 940). SETTING: Hospitals and associated private practices. PATIENT(S): Previously pregnant women (n = 268) within reproductive age in matched pairs. INTERVENTION(S): Retrospective analysis of surgical reports and self-administered questionnaires...
November 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/29067577/impact-of-hospital-and-surgeon-case-volume-on-morbidity-in-colorectal-endometriosis-management-a-plea-to-define-criteria-for-expert-centers
#11
Sofiane Bendifallah, Horace Roman, Chrystel Rubod, Pierre Leguevaque, Antoine Watrelot, Nicolas Bourdel, Marcos Ballester, Emile Darai
National and international guidelines recommend referring patients with severe forms of endometriosis to expert centers. However, there is a lack of clear criteria to define an expert center. We examined the roles of surgeon and hospital procedure volumes as determinants of morbidity in deep infiltrating endometriosis of the rectum and sigmoid colon (DIERS). METHODS: We conducted a French retrospective multicenter study of hospital facilities performing colorectal surgery for DIERS in 2015...
October 24, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29046621/applying-a-statistical-method-in-transvaginal-ultrasound-training-lessons-from-the-learning-curve-cumulative-summation-test-lc-cusum-for-endometriosis-mapping
#12
Vered H Eisenberg, Juan L Alcazar, Nissim Arbib, Eyal Schiff, Reuven Achiron, Motti Goldenberg, David Soriano
BACKGROUND: Methods available for assessing the learning curve, such as a predefined number of procedures or direct mentoring are lacking. Our aim was to describe the use of a statistical method to identify the minimal training length of an experienced sonographer, newly trained in deep infiltrating endometriosis (DIE) mapping by evaluating the learning curve of transvaginal ultrasound (TVUS) in the preoperative assessment of endometriosis. METHODS: A retrospective study in a tertiary referral center for endometriosis...
2017: Gynecological Surgery
https://www.readbyqxmd.com/read/29024196/pelvic-floor-muscle-assessment-at-3-and-4-dimensional-transperineal-ultrasound-in-women-with-endometriosis-with-or-without-retroperitoneal-infiltration-a-step-towards-complete-functional-assessment
#13
Mohamed Mabrouk, Diego Raimondo, Simona Del Forno, Federica Baruffini, Alessandro Arena, Arianna Benfenati, Aly Youssef, Valentina Martelli, Renato Seracchioli
OBJECTIVES: Previous studies, comparing women with deep infiltrating endometriosis (DIE) and healthy controls, underlined an association between pelvic floor muscle (PFM) hypertonic dysfunction and deep lesions. The aim of the study is to compare the morphometry of pelvic floor muscle (PFM) in women affected by ovarian endometriosis with or without DIE, to assess the impact of retroperitoneal infiltration by the disease on PFM function. METHODS: A prospective study was conducted between March 2015 to December 2016 on symptomatic women with clinical and sonographic diagnosis of ovarian endometriosis with or without DIE, submitted to laparoscopic surgery...
October 11, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29023195/depth-of-intestinal-wall-infiltration-and-clinical-presentation-of-deep-infiltrating-endometriosis-evaluation-of-553-consecutive-cases
#14
Roberto Rossini, Giorgio Lisi, Anna Pesci, Marcello Ceccaroni, Giuseppe Zamboni, Irene Gentile, Lorenzo Rettore, Giacomo Ruffo
INTRODUCTION: Intestinal involvement in endometriosis was first described by Sampson in 1922. The reported incidence ranges between 3% and 37% in patients diagnosed with endometriosis. In literature, there are few studies that correlate the severity of endometriosis (in terms of intestinal infiltration) and its clinical presentation. The aim of this study was to review the correlation between the severity of symptoms, the depth of intestinal wall infiltration, and lymph node involvement in our tertiary referral center...
October 12, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28992748/composition-of-the-stroma-in-the-human-endometrium-and-endometriosis
#15
Lutz Konrad, Jessica Kortum, Rai Nabham, Judith Gronbach, Raimund Dietze, Frank Oehmke, Eniko Berkes, Hans-Rudolf Tinneberg
To analyze whether the endometrial and endometriotic microenvironment is involved in the pathogenesis of endometriosis, we characterized the stromal composition. We used CD90 for fibroblasts, α-smooth muscle actin for myofibroblasts as well as CD10 and CD140b for mesenchymal stromal cells. Quantification of eutopic endometrial stroma of cases without endometriosis showed a high percentage of stromal cells positive for CD140b (80.7%) and CD10 (67.4%), a moderate number of CD90-positive cells (57.9%), and very few α-smooth muscle actin-positive cells (8...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/28990723/mri-findings-in-deep-infiltrating-endometriosis-a-pictorial-essay
#16
Anitha L Thalluri, Steven Knox, Thi Nguyen
Endometriosis is an important gynaecological disorder which can impact significantly on an individual's quality of life and has major implications on fertility. Deep infiltrating endometriosis is a severe form of endometriosis which can cause obliteration of anatomic compartments. Laparoscopy remains the gold standard for diagnosis of endometriosis, although is an invasive procedure that has the potential to be hindered by obliterative disease. Ultrasound is often employed as the first-line imaging modality when endometriosis is suspected, however, MRI is more accurate in assessment of complex disease...
October 9, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/28980163/mri-for-adenomyosis-a-pictorial-review
#17
REVIEW
Lisa Agostinho, Rita Cruz, Filipa Osório, João Alves, António Setúbal, Adalgisa Guerra
Adenomyosis is defined as the presence of ectopic endometrial glands and stroma within the myometrium. It is a disease of the inner myometrium and results from infiltration of the basal endometrium into the underlying myometrium. Transvaginal ultrasonography (TVUS) and magnetic resonance imaging (MRI) are the main radiologic tools for this condition. A thickness of the junctional zone of at least 12 mm is the most frequent MRI criterion in establishing the presence of adenomyosis. Adenomyosis can appear as a diffuse or focal form...
October 4, 2017: Insights Into Imaging
https://www.readbyqxmd.com/read/28970135/pregnancy-outcomes-after-controlled-ovarian-hyperstimulation-in-women-with-endometriosis-associated-infertility-gnrh-agonist-versus-gnrh-antagonist
#18
K Kolanska, J Cohen, S Bendifallah, L Selleret, J-M Antoine, N Chabbert-Buffet, E Darai, E-M d'Argent
BACKGROUND OR OBJECTIVE: Endometriosis is common in women referred for infertility. In vitro fertilization provides good results but the choice of the best-controlled ovarian hyperstimulation protocol remains a subject of debate. The objective of this retrospective study was to compare pregnancy outcomes in women with endometriosis-associated infertility after COH with a long agonist protocol or a six-week oral contraception-antagonist protocol. MATERIAL AND METHODS: Retrospective analysis of a prospective database identified 284 COH cycles - 165 with GnRH-agonist protocol (GnRH-agonist group) and 119 with GnRH-antagonist protocol (GnRH-antagonist group) - in 218 women, with endometriosis from January 2013 to October 2015...
September 29, 2017: Journal of gynecology obstetrics and human reproduction
https://www.readbyqxmd.com/read/28969513/hoxb4-immunoreactivity-in-endometrial-tissues-from-women-with-or-without-endometriosis
#19
Ghadeer M AlKusayer, Julia R Pon, Bo Peng, Christian Klausen, Sarka Lisonkova, Mary Kinloch, Paul Yong, Eman M S Muhammad, Peter C K Leung, Mohamed A Bedaiwy
Endometriosis is a common disease characterized by the presence of ectopic endometrial tissue. Although the pathogenesis of endometriosis remains unclear, several factors have been implicated, including the dysregulation of homeobox ( HOX) genes. Our objective was to investigate the localization and immunoreactivity of HOXB4 in endometrial tissues from women with or without endometriosis. We studied samples of eutopic endometrium (EE), endometriomas (Eoma), superficial endometriosis (SE), and deep infiltrating endometriosis (DIE) from 34 women with endometriosis, as well as eutopic endometrium from 38 women without endometriosis (EC)...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/28964962/combined-laparoscopic-and-cystoscopic-approach-in-large-deep-infiltrating-endometriosis-of-the-bladder
#20
J-C Millochau, E Stochino-Loi, G Defortescu, B Darwish, H Roman
Resection of endometriosis nodules infiltrating the bladder is routinely performed by laparoscopy. However, laparoscopic resection may lead to inadvertent loss of healthy bladder tissue. Conversely, when bladder nodules are treated by cystoscopy alone, resection may be incomplete. A combined laparoscopic-cystoscopic approach allows safe and controlled resection. The video reports the procedure performed in a 33 year-old primipara who presented with a 40mm bladder nodule. The laparoscopic step is carried out by the gynecologist, who separates the bladder from the uterus and opens the vesico-vaginal space...
September 28, 2017: Journal of gynecology obstetrics and human reproduction
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