keyword
MENU ▼
Read by QxMD icon Read
search

Tuberculosis and diabetes mellitus

keyword
https://www.readbyqxmd.com/read/29440162/sequelae-of-multidrug-resistant-tuberculosis-protocol-for-a-systematic-review-and-meta-analysis
#1
Kefyalew Addis Alene, Archie C A Clements, Emma S McBryde, Ernesto Jaramillo, Knut Lonnroth, Debebe Shaweno, Kerri Viney
INTRODUCTION: The sequelae of multidrug-resistant tuberculosis (MDR-TB) are poorly understood and inconsistently reported. We will aim to assess the existing evidence for the clinical, psychological, social and economic sequelae of MDR-TB and to assess the health-related quality of life in patients with MDR-TB. METHODS AND ANALYSIS: We will perform a systematic review and meta-analysis of published studies reporting sequelae of MDR-TB. We will search PubMed, SCOPUS, ProQuest, Web of Science and PsychINFO databases up to 5 September 2017...
February 10, 2018: BMJ Open
https://www.readbyqxmd.com/read/29430189/the-correlation-between-ct-features-and-glycosylated-hemoglobin-level-in-patients-with-t2dm-complicated-with-primary-pulmonary-tuberculosis
#2
Li-Li Xia, Su-Fen Li, Kan Shao, Xin Zhang, Shan Huang
To investigate the correlation between computed tomography (CT) features and glycosylated hemoglobin (HbAlc) levels in patients with type 2 diabetes mellitus (T2DM) complicated with primary pulmonary tuberculosis (PTB). One hundred and eighty untreated PTB patients complicated with T2DM were selected. Based on the HbAlc level, the patients were divided into three groups: HbAlc level <7% (Group I: 32 patients), 7%-9% (Group II: 48 patients), and >9% (Group III: 100 patients). The changes of CT manifestations and HbAlc were analyzed after TB and T2DM treatment...
2018: Infection and Drug Resistance
https://www.readbyqxmd.com/read/29429215/-a-clinican-linical-analysis-of-29-cases-of-chronic-pulmonary-aspergillosis
#3
L Y Xu, G X Lai, Q Hu, L Zhang, D L Liu, G B Zhu, X H Li, H H Shi, C Xu, Y H Yu, Y W Bao, W Chen
Objective: To improve the understanding of chronic pulmonary aspergillosis (CPA) by analyzing the clinical manifestations, imaging and pathological features, diagnosis, treatment and prognosis of this disease. Methods: Cases of CPA, proven by microbiological evidence based on pathological study in Fuzhou General Hospital of the People's Liberation Army and Affiliated Fuzhou City First Hospital of Fijian Medical University from January 2006 to October 2016 were retrospectively analyzed. Results: The patients consisted of 17 males and 12 females, aged 24 to 75 years, mean (42±16) years...
February 12, 2018: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/29390977/acute-biliary-events-during-anti-tuberculosis-treatment-hospital-case-series-and-a-nationwide-cohort-study
#4
Lih-Yu Chang, Chih-Hsin Lee, Chia-Hao Chang, Ming-Chia Lee, Meng-Rui Lee, Jann-Yuan Wang, Li-Na Lee
BACKGROUND: Tuberculosis (TB) remains one of the major infectious diseases worldwide. Adverse reactions are common during TB treatment. Few reports, however, are available on treatment-related acute biliary events (ABEs), such as cholelithiasis, biliary obstruction, acute cholecystitis, and cholangitis. METHODS: We first report four pulmonary TB patients who developed ABEs during anti-TB treatment. Abdominal sonography revealed multiple gall stones with dilated intrahepatic ducts in three patients and cholecystitis in one patient...
February 1, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29382589/the-prevalence-and-determinants-of-active-tuberculosis-among-diabetes-patients-in-cape-town-south-africa-a-high-hiv-tb-burden-setting
#5
Natacha Berkowitz, Adaeze Okorie, Rene Goliath, Naomi Levitt, Robert J Wilkinson, Tolu Oni
AIMS: Studies addressing the association between diabetes mellitus (DM) and tuberculosis (TB) in sub-Saharan Africa are limited. We assessed the prevalence of active TB among DM patients at a primary care clinic, and identified risk factors for prevalent TB. METHODS: A cross-sectional study was conducted in adult DM patients attending a clinic in Khayelitsha, Cape Town. Participants were screened for active TB (symptom screening and microbiological diagnosis) and HIV...
January 27, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29379307/performance-of-computed-tomography-versus-chest-radiography-in-patients-with-pulmonary-tuberculosis-with-and-without-diabetes-at-a-tertiary-hospital-in-riyadh-saudi-arabia
#6
Yosra M Alkabab, Mushira A Enani, Nouf Y Indarkiri, Scott K Heysell
Background: Prior research suggests that diabetes mellitus (DM) is associated with increasing risk for developing cavitary lung disease in patients with pulmonary tuberculosis (TB). Additionally, chest computed tomography (CT) scan may be more sensitive than chest X-ray in detecting cavitary disease in such patients. The aim of this study was to compare the performance of chest CT to chest X-ray in detecting cavitary lung disease and to compare the frequency of cavities between TB patients with DM and without DM...
2018: Infection and Drug Resistance
https://www.readbyqxmd.com/read/29325084/metformin-use-reverses-the-increased-mortality-associated-with-diabetes-mellitus-during-tuberculosis-treatment
#7
Nicholas R Degner, Jann-Yuan Wang, Jonathan E Golub, Petros C Karakousis
Background: The global type 2 diabetes mellitus (DM) epidemic threatens progress made in reducing tuberculosis (TB)-related mortality worldwide. Previous clinical studies have not fully evaluated potential confounding variables in addressing the impact of DM on TB treatment outcomes. The antidiabetic agent metformin regulates autophagy and may play a role as a host-directed therapeutic adjuvant to antitubercular treatment. Methods: We conducted a retrospective cohort study comprising patients aged ≥13 years undergoing treatment for culture-confirmed, drug-susceptible pulmonary TB...
January 6, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29297449/prevalence-of-dysglycemia-and-clinical-presentation-of-pulmonary-tuberculosis-in-western-india
#8
V Mave, S Meshram, R Lokhande, D Kadam, S Dharmshale, R Bharadwaj, A Kagal, N Pradhan, S Deshmukh, S Atre, T Sahasrabudhe, M Barthwal, S Meshram, A Kakrani, V Kulkarni, S Raskar, N Suryavanshi, R Shivakoti, S Chon, E Selvin, A Gupte, A Gupta, N Gupte, J E Golub
SETTING: Pune, India. OBJECTIVES: To estimate the prevalence and risk factors of pre-diabetes mellitus (DM) and DM, and its associations with the clinical presentation of tuberculosis (TB). DESIGN: Screening for DM was conducted among adults (age  18 years) with confirmed TB between December 2013 and January 2017. We used multinomial regression to evaluate the risk factors for pre-DM (glycated hemoglobin [HbA1c]  5.7-6.5% or fasting glucose 100-125 mg/dl) and DM (HbA1c  6...
December 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/29297445/tuberculosis-among-the-elderly-in-tanzania-disease-presentation-and-initial-response-to-treatment
#9
T Nagu, R Ray, P Munseri, C Moshiro, G Shayo, R Kazema, F Mugusi, K Pallangyo
BACKGROUND: Reports on tuberculosis (TB) presentation among the elderly in sub-Sahara Africa are scarce at a time when the elderly population is increasing. This dearth of information is likely to lead to an increase in the number of undetected TB cases in the region. OBJECTIVE: To describe TB presentation and response to anti-tuberculosis treatment at 2 months among elderly patients. METHODS: Consecutive patients referred to TB centres in Dar es Salaam, Tanzania, underwent clinical, microbiological and chest X-ray (CXR) evaluations at baseline and after 2 months of anti-tuberculosis treatment...
December 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/29297440/diabetes-and-poor-tuberculosis-treatment-outcomes-issues-and-implications-in-data-interpretation-and-analysis
#10
P Huangfu, F Pearson, C Ugarte-Gil, J Critchley
Tuberculosis (TB) remains one of the 10 leading causes of death worldwide, especially in low- and middle-income countries. We conducted a systematic review and meta-analysis including 88 studies examining the association between diabetes mellitus (DM) and TB treatment outcomes. However, we found several common methodological problems among them, including inappropriate adjustments for confounding factors, not using optimal statistical methods for 'time to event' data, misclassification in exposure (DM) and outcomes (TB treatment outcomes) due to study design and non-standardisation of definitions, misunderstanding of basic study design concept, standardisation of TB treatment outcomes and quality control of publications...
December 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/29297431/feasibility-and-yield-of-screening-for-non-communicable-diseases-among-treated-tuberculosis-patients-in-peru
#11
A L Byrne, B J Marais, C D Mitnick, F L Garden, L Lecca, C Contreras, Y Yauri, F Garcia, G B Marks
INTRODUCTION: The increasing prevalence of non-communicable diseases (NCDs) poses a major challenge to low- and middle-income countries. Patients' engagement with health services for anti-tuberculosis treatment provides an opportunity for screening for NCDs and for linkage to care. METHODS: We explored the feasibility and yield of screening for NCDs in patients treated for tuberculosis (TB) in Lima, Peru, as part of a study focused on chronic respiratory sequelae...
January 1, 2018: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/29297421/tuberculosis-and-diabetes-in-low-and-moderate-tuberculosis-incidence-countries
#12
P-H Lee, H Fu, M-R Lee, M Magee, H-H Lin
In countries with low and moderate incidence of tuberculosis (TB), the disease tends to concentrate in specific high-risk populations such as people with diabetes mellitus (DM). We review the updated evidence on the association between 1) DM and active TB, and 2) DM and latent tuberculous infection (LTBI), and 3) we summarize the findings on the population-level impact of DM on TB epidemiology, with particular focus on low- and moderate-incidence settings. We conducted an updated review of studies on DM and active TB, and found 11 more cohort studies published after the previous systematic review from 2008...
January 1, 2018: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/29224833/hemostasis-and-lipoprotein-indices-signify-exacerbated-lung-injury-in-tuberculosis-with-diabetes-comorbidity
#13
Zhengwei Dong, Jingyun Shi, Anca Dorhoi, Jie Zhang, Adiilah K Soodeen-Lalloo, Wenlin Chen, Hongyun Yin, Wei Sha, Weitong Li, Ruijuan Zheng, Zhonghua Liu, Hua Yang, Lianhua Qin, Jie Wang, Xiaochen Huang, Chunyan Wu, Stefan H E Kaufmann, Yonghong Feng
BACKGROUND: Exacerbated immunopathology is a frequent consequence of tuberculosis (TB) that is complicated by diabetes mellitus (DM), yet the underlying mechanisms are still poorly defined. METHODS: In the two groups of age- and gender-matched TB patients with (DM-TB) and without DM (NDM-TB), we microscopically evaluated the areas of caseous necrosis and graded the extent of perinecrotic fibrosis in lung biopsies from the sputum smear-negative (SN) patients. We scored acid-fast bacilli in smear-positive (SP) patients and compiled computed tomography data from both SN-TB and SP-TB patients...
December 7, 2017: Chest
https://www.readbyqxmd.com/read/29207803/radiological-manifestations-of-pulmonary-tuberculosis-a-comparative-study-between-immunocompromised-and-immunocompetent-patients
#14
Manoj Mathur, Rajesh K Badhan, Sudesh Kumari, Navkiran Kaur, Saryu Gupta
Introduction: Pulmonary tuberculosis has atypical radiological manifestations in patients with underlying immunocompromised disease like diabetes and human immunodeficient virus infection. Computed tomography has important role in such patients for early diagnosis of disease and management to minimize complication. Aim: To evaluate and compare the computed tomography chest features of pulmonary tuberculosis in between immunocompromised patients and immunocompetent patients...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29206500/molecular-property-diagnostic-suite-mpds-development-of-disease-specific-open-source-web-portals-for-drug-discovery
#15
S Nagamani, A S Gaur, K Tanneeru, G Muneeswaran, S S Madugula, Mpds Consortium, D Druzhilovskiy, V V Poroikov, G N Sastry
Molecular property diagnostic suite (MPDS) is a Galaxy-based open source drug discovery and development platform. MPDS web portals are designed for several diseases, such as tuberculosis, diabetes mellitus, and other metabolic disorders, specifically aimed to evaluate and estimate the drug-likeness of a given molecule. MPDS consists of three modules, namely data libraries, data processing, and data analysis tools which are configured and interconnected to assist drug discovery for specific diseases. The data library module encompasses vast information on chemical space, wherein the MPDS compound library comprises 110...
November 2017: SAR and QSAR in Environmental Research
https://www.readbyqxmd.com/read/29189980/patients-with-type-1-diabetes-mellitus-have-impaired-il-1%C3%AE-production-in-response-to-mycobacterium-tuberculosis
#16
E Lachmandas, K Thiem, C van den Heuvel, A Hijmans, B E de Galan, C J Tack, M G Netea, R van Crevel, J A van Diepen
Patients with diabetes mellitus have an increased risk of developing tuberculosis. Although the underlying mechanism is unclear, evidence suggests a role for chronic hyperglycaemia. We examined the influence of hyperglycaemia on Mycobacterium tuberculosis-induced cytokine responses in patients with type 1 diabetes mellitus (T1D). Peripheral blood mononuclear cells (PBMCs) from 24 male T1D patients with sub-optimal glucose control [HbA1c > 7.0% (53 mmol/L)] and from 24 age-matched male healthy controls were stimulated with M...
November 30, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29168465/investigation-of-the-risk-factors-for-pulmonary-tuberculosis-a-case-control-study-among-saharia-tribe-in-gwalior-district-madhya-pradesh-india
#17
Jyothi Bhat, V G Rao, R K Sharma, M Muniyandi, Rajiv Yadav, M K Bhondley
BACKGROUND & OBJECTIVES: Prevalence of pulmonary tuberculosis (PTB) is known to be high in the indigenous tribal community Saharia in Madhya Pradesh, India. The risk factors for PTB are not well known among them. This study was done to determine various risk factors associated with PTB in the indigenous community Saharia. METHODS: A prevalence survey was conducted among Saharias of Gwalior district of Madhya Pradesh. The population surveyed was 12,123 which was the source of cases and controls for the present study...
July 2017: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29161276/association-between-diabetes-mellitus-and-active-tuberculosis-a-systematic-review-and-meta-analysis
#18
Rami H Al-Rifai, Fiona Pearson, Julia A Critchley, Laith J Abu-Raddad
The burgeoning epidemic of diabetes mellitus (DM) is one of the major global health challenges. We systematically reviewed the published literature to provide a summary estimate of the association between DM and active tuberculosis (TB). We searched Medline and EMBASE databases for studies reporting adjusted estimates on the TB-DM association published before December 22, 2015, with no restrictions on region and language. In the meta-analysis, adjusted estimates were pooled using a DerSimonian-Laird random-effects model, according to study design...
2017: PloS One
https://www.readbyqxmd.com/read/29108749/sensitivity-and-specificity-of-quantiferon-tb-gold-plus-compared-with-quantiferon-tb-gold-in-tube-and-t-spot-tb-on-active-tuberculosis-in-japan
#19
Jin Takasaki, Toshie Manabe, Eriko Morino, Yoshikazu Muto, Masao Hashimoto, Motoyasu Iikura, Shinyu Izumi, Haruhito Sugiyama, Koichiro Kudo
BACKGROUND: The QuantiFERON-TB Gold Plus (QFT-Plus) was introduced in 2015 as a new generation of interferon-gamma release assays (IGRAs) designed to detect Mycobacterium tuberculosis infection (TB). Examination of its diagnostic accuracy is crucial before it is launched in Japan. METHOD: We examined 99 patients with laboratory-confirmed active TB (patients) and 117 healthy volunteers with no risk of TB infection (controls) at a medical center in Tokyo, Japan. Blood samples were collected from both the patients and controls and tested using three types of IGRAs: the QFT-Plus, the QuantiFERON-TB Gold In-Tube (QFT-GIT), and the T-SPOT...
November 3, 2017: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/29105294/regional-differences-in-the-incidence-of-tuberculosis-among-patients-with-newly-diagnosed-diabetes-mellitus
#20
Bo Ram Yang, Young-Ae Kang, Heo Eun Young, Bo Kyung Koo, Nam-Kyong Choi, Seung-Sik Hwang, Chang-Hoon Lee
OBJECTIVE: There are regional differences in the burden of tuberculosis (TB). Although these differences might be explained by regional differences in the risk factors of TB, whether such risk factors are actually associated with the regional differences in the TB burden remains unclear. This study aimed to investigate the relationship between the risk factors of and regional differences in TB incidence. METHODS: A cohort study applying nationwide claims database in Republic of Korea included patients newly diagnosed with type 2 diabetes mellitus (DM) in 2009...
November 4, 2017: Clinical Respiratory Journal
keyword
keyword
89836
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"