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https://www.readbyqxmd.com/read/28236994/-electroconvulsive-therapy-and-level-of-evidence-from-causality-to-dose-effect-relationship
#1
J-A Micoulaud-Franchi, C Quilès, M Cermolacce, R Belzeaux, M Adida, E Fakra, J-M Azorin
OBJECTIVES: The first objective of this article is to summarize the history of electroconvulsive therapy (ECT) in psychiatry in order to highlight the transition from clinical level of evidence based on phenomenological descriptions to controlled trial establishing causal relationship. The second objective is to apply the criteria of causation for ECT, to focus on the dose-effect relationship criteria, and thus to analyze the conditions of application of these criteria for ECT. METHODS: A literature review exploring the use of electricity, ECT and electroencephalography (EEG) in psychiatry was conducted...
December 2016: L'Encéphale
https://www.readbyqxmd.com/read/28224113/intensity-modulated-radiation-therapy-with-stereotactic-body-radiation-therapy-boost-for-unfavorable-prostate-cancer-a-report-on-3-year-toxicity
#2
Ima Paydar, Abigail Pepin, Robyn A Cyr, Joseph King, Thomas M Yung, Elizabeth G Bullock, Siyuan Lei, Andrew Satinsky, K William Harter, Simeng Suy, Anatoly Dritschilo, John H Lynch, Thomas P Kole, Sean P Collins
BACKGROUND: Recent data suggest that intensity-modulated radiation therapy (IMRT) plus brachytherapy boost for unfavorable prostate cancer provides improved biochemical relapse-free survival over IMRT alone. Stereotactic body radiation therapy (SBRT) may be a less invasive alternative to brachytherapy boost. Here, we report the 3-year gastrointestinal (GI) and genitourinary (GU) toxicities of IMRT plus SBRT boost. MATERIALS AND METHODS: Between March 2008 and September 2012, patients with prostate cancer were treated with robotic SBRT (19...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/28220036/proposal-for-a-new-predictive-model-of-short-term-mortality-after-living-donor-liver-transplantation-due-to-acute-liver-failure
#3
COMPARATIVE STUDY
Hyun Sik Chung, Yu Jung Lee, Yun Sung Jo
BACKGROUND Acute liver failure (ALF) is known to be a rapidly progressive and fatal disease. Various models which could help to estimate the post-transplant outcome for ALF have been developed; however, none of them have been proved to be the definitive predictive model of accuracy. We suggest a new predictive model, and investigated which model has the highest predictive accuracy for the short-term outcome in patients who underwent living donor liver transplantation (LDLT) due to ALF. MATERIAL AND METHODS Data from a total 88 patients were collected retrospectively...
February 21, 2017: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/28182518/clinical-evaluation-of-a-bioactive-beta-glucan-gel-in-the-treatment-of-hard-to-heal-wounds
#4
B King, S Barrett, K F Cutting
OBJECTIVE: The aim of this evaluation is to assess the effects of a wound healing gel in a wounds of different aetiologies. METHOD: Data was recorded on the wound surface area, tissue type, and patient level of wound pain at baseline (0) and at weeks 1, 2, 3, 4, and 8. RESULTS: Of the total 39 patients enrolled in the study, 26 patients who complied with the protocol criteria completed the minimum four-week study period. During the 12-week evaluation period, seven of the 26 wounds fully healed and an additional eight wounds showed a reduction in size of more than 50 %...
February 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28168811/transobturator-tape-operation-for-the-treatment-of-stress-urinary-incontinence-in-postmenopausal-women-aged-over-65%C3%A2-years
#5
Cenk Yasa, Funda Gungor Ugurlucan, Ozlem Dural, Harika Yumru, Cansu Gunaydin, Onay Yalcin
OBJECTIVE: We compared success rates and complication rates in women aged less then and equal to or more than 65 years who had undergone transobturator tape (TOT) surgery for stress urinary incontinence (SUI). METHODS: This was a retrospective cohort study that included patients who underwent surgery to treat SUI. We separated patients into two groups according to age: younger than 65 years and equal to or older than 65 years. Exclusion criteria were patients with history of incontinence surgery, history of radical pelvic surgery, concomitant pelvic organ prolapse repair, detrusor overactivity, and less than 1 year of postoperative follow-up...
February 6, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28165775/treatment-of-depression-and-anxiety-by-naturopathic-physicians-an-observational-study-of-naturopathic-medicine-within-an-integrated-multidisciplinary-community-health-center
#6
Cindy Breed, Catherine Bereznay
OBJECTIVES: This project was designed to assess the quality of care received by patients with depression and anxiety who were seen by naturopathic physicians in a community health center. METHODS: The Natural Medicine Quality Improvement Project for the Treatment of Depression and Anxiety (NMQP-DA) was conducted over a 26-month period from December 2009 through February 2012 at HealthPoint, a non-profit, consumer-governed, community health center network located in suburban King County, Washington...
February 6, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28157371/search-for-b-%C3%A2-k-%C3%AF-%C3%AF-at-the-babar-experiment
#7
J P Lees, V Poireau, V Tisserand, E Grauges, A Palano, G Eigen, D N Brown, Yu G Kolomensky, H Koch, T Schroeder, C Hearty, T S Mattison, J A McKenna, R Y So, V E Blinov, A R Buzykaev, V P Druzhinin, V B Golubev, E A Kravchenko, A P Onuchin, S I Serednyakov, Yu I Skovpen, E P Solodov, K Yu Todyshev, A J Lankford, J W Gary, O Long, A M Eisner, W S Lockman, W Panduro Vazquez, D S Chao, C H Cheng, B Echenard, K T Flood, D G Hitlin, J Kim, T S Miyashita, P Ongmongkolkul, F C Porter, M Röhrken, Z Huard, B T Meadows, B G Pushpawela, M D Sokoloff, L Sun, J G Smith, S R Wagner, D Bernard, M Verderi, D Bettoni, C Bozzi, R Calabrese, G Cibinetto, E Fioravanti, I Garzia, E Luppi, V Santoro, A Calcaterra, R de Sangro, G Finocchiaro, S Martellotti, P Patteri, I M Peruzzi, M Piccolo, A Zallo, S Passaggio, C Patrignani, B Bhuyan, U Mallik, C Chen, J Cochran, S Prell, H Ahmed, A V Gritsan, N Arnaud, M Davier, F Le Diberder, A M Lutz, G Wormser, D J Lange, D M Wright, J P Coleman, E Gabathuler, D E Hutchcroft, D J Payne, C Touramanis, A J Bevan, F Di Lodovico, R Sacco, G Cowan, Sw Banerjee, D N Brown, C L Davis, A G Denig, M Fritsch, W Gradl, K Griessinger, A Hafner, K R Schubert, R J Barlow, G D Lafferty, R Cenci, A Jawahery, D A Roberts, R Cowan, R Cheaib, S H Robertson, B Dey, N Neri, F Palombo, L Cremaldi, R Godang, D J Summers, P Taras, G De Nardo, C Sciacca, G Raven, C P Jessop, J M LoSecco, K Honscheid, R Kass, A Gaz, M Margoni, M Posocco, M Rotondo, G Simi, F Simonetto, R Stroili, S Akar, E Ben-Haim, M Bomben, G R Bonneaud, G Calderini, J Chauveau, G Marchiori, J Ocariz, M Biasini, E Manoni, A Rossi, G Batignani, S Bettarini, M Carpinelli, G Casarosa, M Chrzaszcz, F Forti, M A Giorgi, A Lusiani, B Oberhof, E Paoloni, M Rama, G Rizzo, J J Walsh, A J S Smith, F Anulli, R Faccini, F Ferrarotto, F Ferroni, A Pilloni, G Piredda, C Bünger, S Dittrich, O Grünberg, M Heß, T Leddig, C Voß, R Waldi, T Adye, F F Wilson, S Emery, G Vasseur, D Aston, C Cartaro, M R Convery, J Dorfan, W Dunwoodie, M Ebert, R C Field, B G Fulsom, M T Graham, C Hast, W R Innes, P Kim, D W G S Leith, S Luitz, V Luth, D B MacFarlane, D R Muller, H Neal, B N Ratcliff, A Roodman, M K Sullivan, J Va'vra, W J Wisniewski, M V Purohit, J R Wilson, A Randle-Conde, S J Sekula, M Bellis, P R Burchat, E M T Puccio, M S Alam, J A Ernst, R Gorodeisky, N Guttman, D R Peimer, A Soffer, S M Spanier, J L Ritchie, R F Schwitters, J M Izen, X C Lou, F Bianchi, F De Mori, A Filippi, D Gamba, L Lanceri, L Vitale, F Martinez-Vidal, A Oyanguren, J Albert, A Beaulieu, F U Bernlochner, G J King, R Kowalewski, T Lueck, I M Nugent, J M Roney, N Tasneem, T J Gershon, P F Harrison, T E Latham, R Prepost, S L Wu
We search for the rare flavor-changing neutral current process B^{+}→K^{+}τ^{+}τ^{-} using data from the BABAR experiment. The data sample, collected at the center-of-mass energy of the ϒ(4S) resonance, corresponds to a total integrated luminosity of 424  fb^{-1} and to 471×10^{6}  BB[over ¯] pairs. We reconstruct one B meson, produced in the ϒ(4S)→B^{+}B^{-} decay, in one of many hadronic decay modes and search for activity compatible with a B^{+}→K^{+}τ^{+}τ^{-} decay in the rest of the event...
January 20, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28155608/helical-tomotherapy-versus-conventional-technique-for-post-mastectomy-left-sided-breast-cancer-dosimetric-study
#8
M O Alshabanah, Mohamed Hegazy, Belal Moftah, Mohammad Shabanah
METHODS AND MATERIALS: Treatment plans were generated for 5 post mastectomy left sided breast cancer patients treated at king Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia, comparing three-dimensional technique with the HT planning. The prescribed dose was 50 Gy in 25 fractions; the planning target volume (chest wall and nodal volumes) was contoured according to RTOG atlas and the heart, lungs, spinal cord and contralateral breast were contoured as Organs at Risks (OARs)...
February 1, 2017: Reviews on Recent Clinical Trials
https://www.readbyqxmd.com/read/28151456/comparison-of-two-approaches-to-lateral-osteotomy-in-saudi-patients
#9
Ahmad A Mirza, Osama A Marglani, Mian U Farooq, Talal A Al-Khatib, Waed S Jameel, Noran A Sultan, Mohammed S Aly
BACKGROUND: Nasal deformity is an abnormality in the appearance of the nose due to either congenital defect or trauma. In traumatic cases, patients often present with combined functional and cosmetic complaints. Therefore, otolaryngologists take into account both breathing and aesthetic nasal issues. OBJECTIVES: To evaluate the changes in the nasal dorsum and base; compare breathing and aesthetic satisfaction scores between two approaches to lateral nasal osteotomy: low-to-low and low-to-high...
January 2017: Annals of Saudi Medicine
https://www.readbyqxmd.com/read/28135352/implementation-of-lung-cancer-screening-in-the-veterans-health-administration
#10
Linda S Kinsinger, Charles Anderson, Jane Kim, Martha Larson, Stephanie H Chan, Heather A King, Kathryn L Rice, Christopher G Slatore, Nichole T Tanner, Kathleen Pittman, Robert J Monte, Rebecca B McNeil, Janet M Grubber, Michael J Kelley, Dawn Provenzale, Santanu K Datta, Nina S Sperber, Lottie K Barnes, David H Abbott, Kellie J Sims, Richard L Whitley, R Ryanne Wu, George L Jackson
Importance: The US Preventive Services Task Force recommends annual lung cancer screening (LCS) with low-dose computed tomography for current and former heavy smokers aged 55 to 80 years. There is little published experience regarding implementing this recommendation in clinical practice. Objectives: To describe organizational- and patient-level experiences with implementing an LCS program in selected Veterans Health Administration (VHA) hospitals and to estimate the number of VHA patients who may be candidates for LCS...
January 30, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28133685/impact-of-acute-kidney-injury-on-long-term-mortality-and-progression-to-chronic-kidney-disease-among-critically-ill-children
#11
Najlaa G Al-Otaibi, Maryam Zeinelabdin, Mohamed A Shalaby, Norah Khathlan, Ghadi D Mashat, Amal A Zahrani, Sundus Mw NoorSaeed, Nora M Shalabi, Khalid A Alhasan, Sara N Sharief, Amr S Albanna, Jameela A Kari
To determine the 2-year outcome of acute kidney injury (AKI) following admission to pediatric critical care units (PICU). Methods: A retrospective cohort study was conducted between January 2012 and December 2013. We followed 131 children admitted to PICU, King Abdulaziz University Hospital, Jeddah, Kingdom of Saudi Arabia with a diagnosis of AKI, based on pRIFLE (pediatric risk, injury, failure, loss, and end-stage renal disease), for 2 years. During the study period, 46 children died and 38 of survivors completed the follow-up...
February 2017: Saudi Medical Journal
https://www.readbyqxmd.com/read/28130708/acute-liver-failure-due-to-hepatitis-e-virus-infection-is-associated-with-better-survival-than-other-etiologies-in-indian-patients
#12
Shalimar, Saurabh Kedia, Deepak Gunjan, Ujjwal Sonika, Soumya Jagannath Mahapatra, Baibaswata Nayak, Harpreet Kaur, Subrat Kumar Acharya
BACKGROUND AND AIM: Hepatitis E virus (HEV) is a global disease and an important cause of acute liver failure (ALF) in the Indian subcontinent. The aim of this study was to assess the differences in the course of HEV-ALF as compared to other etiologies of ALF. METHODS: We compared the clinical course, complications, and outcomes of HEV-ALF with other etiologies. We assessed the prognostic factors and compared existing prognostic scores in HEV-ALF patients. RESULTS: One thousand four hundred and sixty-two ALF patients were evaluated between January 1986 and December 2015...
January 27, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28128977/a-tailored-intervention-for-pap-adherence-the-scip-pa-trial
#13
Amy M Sawyer, Tonya S King, Terri E Weaver, Douglas A Sawyer, Miranda Varrasse, Jamie Franks, Alexa Watach, Ann M Kolanowski, Kathy C Richards
OBJECTIVE/BACKGROUND: Positive airway pressure (PAP) is highly efficacious treatment but nonadherence is prevalent with little improvement over the last 15 years. Tailored interventions show promise for promoting adherence to other treatments. The study objective was to examine feasibility and acceptability of a tailored intervention to promote PAP adherence. PARTICIPANTS: The convenience sample met inclusion criteria: newly diagnosed OSA; treatment-naïve; ≥ 18 years...
January 27, 2017: Behavioral Sleep Medicine
https://www.readbyqxmd.com/read/28122322/third-molar-cut-off-value-in-assessing-the-legal-age-of-18-in-saudi-population
#14
Sakher AlQahtani, Alemad Kawthar, Ayman AlAraik, Ahmad AlShalan
: Teeth plays a major role in forensic sciences especially in age assessment of an individual, which can be used to aid in criminal or civil matters. The importance of teeth comes from their ability to survive inhumation well and because they are hardly affected by exogenous and endogenous factors. Third molars are the only teeth still developing after the age of 14 years and during the legal age of adulthood, which is 18 years. The consequences of criminal violation can strongly affect the individual's life, it is important to set different parameters to decide whether an individual is a minor or an adult in the absence of documents...
January 11, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28120803/vocal-matching-the-what-the-why-and-the-how
#15
REVIEW
Stephanie L King, Peter K McGregor
Over the years, vocal matching has progressed beyond being an interesting behavioural phenomenon to one that now has relevance to a wide range of fields. In this review, we use birds and cetaceans to explain what vocal matching is, why animals vocally match and how vocal matching can be identified. We show that while the functional aspects of vocal matching are similar, the contexts in which matching is used can differ between taxa. Whereas vocal matching in songbirds facilitates mate attraction and the immediate defence of resources, in parrots and cetaceans it plays a role in the maintenance of social bonds and the promotion of behavioural synchrony...
October 2016: Biology Letters
https://www.readbyqxmd.com/read/28116096/an-inhaled-dose-of-budesonide-induces-genes-involved-in-transcription-and-signaling-in-the-human-airways-enhancement-of-anti-and-proinflammatory-effector-genes
#16
Richard Leigh, Mahmoud M Mostafa, Elizabeth M King, Christopher F Rider, Suharsh Shah, Curtis Dumonceaux, Suzanne L Traves, Andrew McWhae, Tyler Kolisnik, Cora Kooi, Donna M Slater, Margaret M Kelly, Mark Bieda, Anna Miller-Larsson, Robert Newton
Although inhaled glucocorticoids, or corticosteroids (ICS), are generally effective in asthma, understanding their anti-inflammatory actions in vivo remains incomplete. To characterize glucocorticoid-induced modulation of gene expression in the human airways, we performed a randomized placebo-controlled crossover study in healthy male volunteers. Six hours after placebo or budesonide inhalation, whole blood, bronchial brushings, and endobronchial biopsies were collected. Microarray analysis of biopsy RNA, using stringent (≥2-fold, 5% false discovery rate) or less stringent (≥1...
August 2016: Pharmacology Research & Perspectives
https://www.readbyqxmd.com/read/28116023/what-do-they-want-from-us-a-survey-of-em-program-directors-on-em-application-criteria
#17
Kevin King, Dara Kass
INTRODUCTION: Although a relatively young specialty, emergency medicine (EM) is popular among medical students and is one of the most competitive large specialties. Consequently, students increasingly seek more opportunity to differentiate themselves from their colleagues by pursuing more clerkships at the cost of taking out additional loans: this despite the fact that those who match in EM typically do so in their top three choices. We sought to ascertain what factors EM program directors seek in their typical candidate...
January 2017: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28097670/acute-liver-failure-in-scotland-changes-in-aetiology-and-outcomes-over-time-the-scottish-look-back-study
#18
M C Donnelly, J S Davidson, K Martin, A Baird, P C Hayes, K J Simpson
BACKGROUND: Acute liver failure is a rare and devastating clinical condition resulting from sudden loss of hepatic parenchyma and metabolic function. The Scottish Liver Transplant Unit (SLTU) offers specialist management and emergency liver transplantation to patients with acute liver failure from across Scotland. AIM: To describe temporal changes in number of admissions, aetiology of acute liver failure, severity of disease at presentation and outcomes over a 22-year period...
January 18, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28096209/use-of-mixed-methods-research-in-research-on-coronary-artery-disease-diabetes-mellitus-and-hypertension-a-scoping-review
#19
David J T Campbell, Helen Tam-Tham, Kirnvir K Dhaliwal, Braden J Manns, Brenda R Hemmelgarn, Claudia Sanmartin, Kathryn King-Shier
BACKGROUND: Mixed methods research, the use of both qualitative and quantitative methods within 1 program of study, is becoming increasingly popular to allow investigators to explore patient experiences (qualitative) and also measure outcomes (quantitative). Coronary artery disease and its risk factors are some of the most studied conditions; however, the extent to which mixed methods studies are being conducted in these content areas is unknown. We sought to comprehensively describe the characteristics of published mixed methods studies on coronary artery disease and major risk factors (diabetes mellitus and hypertension)...
January 2017: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/28095037/non-invasive-follicular-tumor-with-papillary-like-nuclear-features-niftp-not-a-tempest-in-a-teapot
#20
Nidhi Agrawal, Collette E Abbott, Cheng Liu, Stella Kang, Laura Tipton, Kepal Patel, Mark Persky, Lizabeth King, Fang-Ming Deng, Michael Bannan, Jennifer B Ogilvie, Keith Heller, Steven P Hodak
BACKGROUND: Encapsulated non-invasive follicular variant papillary thyroid cancer (ENIFVPTC) has recently been re-termed noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP). This designation specifically omits the word "cancer" to encourage conservative management since patients with NIFTP tumors have been shown to derive no benefit from completion thyroidectomy or adjuvant radioactive iodine (RAI) therapy. METHODS: IRB approved retrospective study of consecutive cases of tumors from 2007 to 2015 that met pathologic criteria for NIFTP...
January 17, 2017: Endocrine Practice
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