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Clinical Densitometry

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https://www.readbyqxmd.com/read/29049519/association-of-bone-mineral-density-with-the-risk-of-intracranial-aneurysm
#1
Yong-Won Shin, Kyung-Il Park, Jangsup Moon, Soon-Tae Lee, Kon Chu, Sang Kun Lee, Jae-Kyu Roh, Keun-Hwa Jung
Importance: Disruption of extracellular matrix integrity is critically involved in both intracranial aneurysm and bone fragility. Furthermore, both intracranial aneurysm and osteoporosis have a female predominance, and sex hormones are considered to affect this discrepancy. Objective: To evaluate the association between bone mineral density and intracranial aneurysm. Design, Setting, and Participants: A cross-sectional study conducted with 14 328 patients who underwent brain magnetic resonance angiography and bone mineral densitometry as a part of a health examination at a specialized center for comprehensive health examination in Seoul, the largest metropolitan area in the Republic of Korea, between December 2004 and November 2015...
October 16, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29038394/factors-associated-with-lumbar-and-femoral-bone-mineral-density-in-kidney-transplants-candidates
#2
Mohammad Aghighi, Mitra Mahdavi Mazdeh, Mohsen Nafar, Vahid Rakhshan
INTRODUCTION: Data on risk factors associated with low bone mineral density are limited in patients with end-stage renal disease. This study evaluated the factors deemed associated with lumbar and femoral Z and T scores. MATERIALS AND METHODS: Clinical and demographic data of 98 patients waiting for kidney transplantation were collected, as well as lumbar and femoral bone densitometries, before transplantation. Osteoporosis and osteopenia and factors associated with bone mineral density were assessed...
October 2017: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29018567/do-we-need-bone-mineral-density-to-estimate-osteoporotic-fracture-risk-a-10-year-prospective-multicentre-validation-study
#3
Andréa Marques, Raquel Lucas, Eugénia Simões, Suzanne M M Verstappen, Johannes W G Jacobs, Jose A P da Silva
OBJECTIVE: Evaluate the performance of FRAX®, with and without bone mineral densitometry (BMD), in predicting the occurrence of fragility fractures over 10 years. METHODS: Participants aged ≥40 years at baseline, with a complete set of data and a minimum of 8.5 years of follow-up were identified from three cohorts (n=2626). Ten-year fracture risk at baseline were estimated with FRAX® and assessed by comparison with observed fractures and receiver operating characteristic analysis...
2017: RMD Open
https://www.readbyqxmd.com/read/28977305/assessment-of-the-late-effects-on-bones-and-on-body-composition-of-children-and-adolescents-treated-for-acute-lymphocytic-leukemia-according-to-brazilian-protocols
#4
Poliana Cristina Carmona Molinari, Henrique Manoel Lederman, Maria Lucia de Martino Lee, Eliana Maria Monteiro Caran
OBJECTIVE: To evaluate the impact of therapy on bone mineral density (BMD) and body composition in survivors of acute lymphoblastic leukemia (ALL) treated in accordance with Brazilian protocols by the Brazilian Cooperative Group of Treatment of Lymphoblastic Leukemia in Childhood (GBTLI) LLA-93 and LLA-99. METHODS: A cross-sectional study with 101 patients was performed. BMD and body composition were evaluated using bone densitometry and were interpreted according to the age group and the reference population...
January 2017: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
https://www.readbyqxmd.com/read/28955207/hydrogen-inhalation-protects-against-ototoxicity-induced-by-intravenous-cisplatin-in-the-guinea-pig
#5
Anette E Fransson, Marta Kisiel, Kristian Pirttilä, Curt Pettersson, Pernilla Videhult Pierre, Göran F E Laurell
Introduction: Permanent hearing loss and tinnitus as side-effects from treatment with the anticancer drug cisplatin is a clinical problem. Ototoxicity may be reduced by co-administration of an otoprotective agent, but the results in humans have so far been modest. Aim: The present preclinical in vivo study aimed to explore the protective efficacy of hydrogen (H2) inhalation on ototoxicity induced by intravenous cisplatin. Materials and Methods: Albino guinea pigs were divided into four groups. The Cispt (n = 11) and Cispt+H2 (n = 11) groups were given intravenous cisplatin (8 mg/kg b...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/28937143/crab-claw-pattern-on-corneal-topography-pellucid-marginal-degeneration-or-inferior-keratoconus
#6
M Koc, K Tekin, M Inanc, P Kosekahya, P Yilmazbas
PurposeTo evaluate the topographic, tomographic, and densitometric properties of patients with pellucid marginal degeneration (PMD) and inferior keratoconus.Patients and methodsRetrospective, comparative case series. Forty-seven eyes of 32 patients with crab claw patterns were identified from 2751 patients with corneal ectasia. They were divided into two groups, inferior keratoconus and PMD, based on clinical findings. The topographic, tomographic, and densitometric measurements were analyzed.ResultsPMD was detected in 11 eyes of eight patients (mean age 50...
September 22, 2017: Eye
https://www.readbyqxmd.com/read/28934883/contrast-enhanced-computed-tomography-enables-quantitative-evaluation-of-tissue-properties-at-intrajoint-regions-in-cadaveric-knee-cartilage
#7
Rachel C Stewart, Juuso T J Honkanen, Harri T Kokkonen, Virpi Tiitu, Simo Saarakkala, Antti Joukainen, Brian D Snyder, Jukka S Jurvelin, Mark W Grinstaff, Juha Töyräs
Objective The aim of this study was to investigate whether the concentration of the anionic contrast agent ioxaglate, as quantitated by contrast-enhanced computed tomography (CECT) using a clinical cone-beam CT (CBCT) instrument, reflects biochemical, histological, and biomechanical characteristics of articular cartilage imaged in an ex vivo, intact human knee joint. Design An osteoarthritic human cadaveric knee joint (91 years old) was injected with ioxaglate (36 mg I/mL) and imaged using CBCT over 61 hours of ioxaglate diffusion into cartilage...
October 2017: Cartilage
https://www.readbyqxmd.com/read/28932558/results-of-quantitative-chest-ct-in-chronic-pulmonary-graft-vs-host-disease-cgvhd-3-years-after-allogeneic-stem-cell-transplantation
#8
Christopher Kloth, Wolfgang M Thaiss, Jürgen Hetzel, Georg Bier, Stefan Wirths, Konstantin Nikolaou, Marius Horger
BACKGROUND: To quantify lung parenchymal changes in symptomatic patients with chronic pulmonary graft-versus-host disease 3 years after allogeneic stem cell transplantation (allo-SCT) by means of CT-densitometry (CTD) and to compare results with those of established pulmonary function tests (PFT). METHODS: The study group consisted of 26 patients with pulmonary cGvHD (19 males, 7 females; mean age, 49.29±15.89; range, 19-72 years). The diagnosis was based on clinical symptoms, PFT and chest-CT findings...
August 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28884215/effect-of-smoking-cessation-on-quantitative-computed-tomography-in-smokers-at-risk-in-a-lung-cancer-screening-population
#9
Bertram J Jobst, Oliver Weinheimer, Mila Trauth, Nikolaus Becker, Erna Motsch, Marie-Luise Groß, Jan Tremper, Stefan Delorme, Anke Eigentopf, Monika Eichinger, Hans-Ulrich Kauczor, Mark O Wielpütz
OBJECTIVE: To longitudinally evaluate effects of smoking cessation on quantitative CT in a lung cancer screening cohort of heavy smokers over 4 years. METHODS: After 4 years, low-dose chest CT was available for 314 long-term ex-smokers (ES), 404 continuous smokers (CS) and 39 recent quitters (RQ) who quitted smoking within 2 years after baseline CT. CT acquired at baseline and after 3 and 4 years was subjected to well-evaluated densitometry software, computing mean lung density (MLD) and 15th percentile of the lung density histogram (15TH)...
September 7, 2017: European Radiology
https://www.readbyqxmd.com/read/28860112/risk-factors-for-falls-in-older-patients-with-cancer
#10
Xiaotao Zhang, Ming Sun, Suyu Liu, Cheuk Hong Leung, Linda Pang, Uday R Popat, Richard Champlin, Holly M Holmes, Vicente Valero, Colin P Dinney, Debu Tripathy, Beatrice J Edwards
OBJECTIVES: A rising number of patients with cancer are older adults (65 years of age and older), and this proportion will increase to 70% by the year 2020. Falls are a common condition in older adults. We sought to assess the prevalence and risk factors for falls in older patients with cancer. METHODS: This is a single-site, retrospective cohort study. Patients who were receiving cancer care underwent a comprehensive geriatric assessments, including cognitive, functional, nutritional, physical, falls in the prior 6 months and comorbidity assessment...
August 31, 2017: BMJ Supportive & Palliative Care
https://www.readbyqxmd.com/read/28835759/associated-factors-of-bone-mineral-density-and-osteoporosis-in-elderly-males
#11
Behzad Heidari, Abdollah Muhammadi, Yahya Javadian, Ali Bijani, Reza Hosseini, Mansour Babaei
BACKGROUND: Low bone mineral density and osteoporosis is prevalent in elderly subjects. This study aimed to determine the associated factors of bone mineral density and osteoporosis in elderly males. METHODS: All participants of the Amirkola health and ageing project cohort aged 60 years and older entered the study. Bone mineral density at femoral neck and lumbar spine was assessed by the dual energy X-ray absorptiometry (DXA) method. Osteoporosis was diagnosed by the international society for clinical densitometry criteria and the association of bone mineral density and osteoporosis with several clinical, demographic and biochemical parameters...
January 2017: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28817393/increased-expiratory-computed-tomography-density-reveals-possible-abnormalities-in-radiologically-preserved-lung-parenchyma-in-idiopathic-pulmonary-fibrosis
#12
Valentina Petroulia, Manuela Funke, Pascal Zumstein, Sabina Berezowska, Lukas Ebner, Thomas Geiser, Nenad Torbica, Johannes Heverhagen, Alexander Poellinger
OBJECTIVES: Idiopathic pulmonary fibrosis (IPF) is a progressive lethal chronic lung disease with unclear pathogenesis. Radiological hallmark is the pattern of usual interstitial pneumonia accentuated in peripheral and basal areas with otherwise preserved lung structure. One hypothesis is that alveolar collapse and consequent induration lead to fibrotic transformation of lung tissue. The aim of the study was to investigate normal-appearing tissue during expiration for signs of collapsibility and differences from other diseases or controls...
August 16, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28802981/errors-in-patient-positioning-for-bone-mineral-density-assessment-by-dual-x-ray-absorptiometry-effect-of-technologist-retraining
#13
Sasivimol Promma, Chanika Sritara, Saowanee Wipuchwongsakorn, Krisanat Chuamsaamarkkee, Chirawat Utamakul, Wichana Chamroonrat, Arpakorn Kositwattanarerk, Yoch Anongpornjossakul, Kanungnij Thamnirat, Boonsong Ongphiphadhanakul
Improper positioning is one of the factors that can lead to incorrect bone mineral density (BMD) results. This study aimed to assess the frequencies of erroneous positioning during three periods: before retraining of the technologists (BR), after retraining (AR), and at the current timepoint 8 years after retraining (C). The BMD images of the first 150 consecutive patients who underwent DXA of the lumbar spine and hip during each of the three periods were retrospectively reviewed. Patients were excluded if they had severe scoliosis, rendering proper positioning impossible...
August 9, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28781228/assessment-of-the-bone-mineral-content-in-the-mandible-by-dual-energy-x-ray-absorptiometry-to-evaluate-short-term-change
#14
Yun Sun, Min Min An, Jingmei Wang, Fan Yang, Liying He, Chad A Dudzek, Congjin Liu, Patrick C Cunniff, Xingdang Liu, Tom V Sanchez
With the objective of being able to assess response to disease or clinical treatment, the densitometry community has long sought the ability to assess short-term change in bone density. The mandible, known to have a high bone turnover, an increased vascularity, and a greater susceptibility to osteoclastic and osteoblastic activities, has long been suggested but has fallen short as a site from which to monitor an early change in the response to a treatment or a disease. The current study developed a method to assess bone density in the superimposed left and right mandibles...
August 3, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28777482/clinical-conformity-between-heel-ultrasound-and-densitometry-in-postmenopausal-women-a-systematic-review
#15
Elżbieta Tabor, Wojciech Pluskiewicz, Kamil Tabor
OBJECTIVES: To assess the conformity between heel ultrasound and densitometry, and the clinical application of densitometry T-score "gold standard" in quantitative ultrasound as a method of osteoporosis diagnosis in postmenopausal women. METHODS: The study is a systematic review of studies published in the last 17 years in PubMed, NLM Gateway, Medline, Embase, and Cochrane Library. Calcaneal quantitative ultrasound sensitivity and specificity were analyzed with regard to densitometry measurements in postmenopausal women...
August 4, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28755448/short-term-in%C3%A2-vivo-precision-of-whole-body-composition-measurements-on-the-horizon-a-densitometer
#16
Michael Nowitz, Paula Monahan
INTRODUCTION: Dual-energy X-ray absorptiometry (DXA) is increasingly being used to assess abnormalities in body composition associated with a wide variety of conditions including obesity, sarcopenia, diabetes, anorexia, human immunodeficiency virus lipodystrophy, malabsorption and neuromuscular disorders. The objective of this study was to determine the short-term in vivo precision and least significant change in serial body composition measurements provided by the Hologic Horizon A densitometer as there is no published, peer reviewed body composition precision data on Horizon scanners in the medical literature...
July 29, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/28748194/recurrent-metatarsal-fractures-in-postmenopausal-woman-with-low-serum-alkaline-phosphatase-a-rare-diagnosis-not-to-miss
#17
Umair Iqbal, Hafsa Anwar, Ahmad Chaudhary, Madiha Alvi, Amy Freeth
Hypophosphatasia (HPP) is a rare inborn error of metabolism due to a loss-of-function mutation in the gene for tissue nonspecific isoenzyme of alkaline phosphatase (ALP) that results in low levels of ALP. The clinical presentation of HPP is variable and in adults can easily be misdiagnosed as other forms of osteomalacia. We present a case of a 53-year-old Caucasian female who was evaluated for recurrent metatarsal fractures. She reported her first metatarsal fracture at age 21, and since then had at least 8 more metatarsal fractures over her lifetime, most without injury other than weight bearing...
July 2017: Journal of Investigative Medicine High Impact Case Reports
https://www.readbyqxmd.com/read/28743412/pseudoexfoliation-signs-in-the-anterior-segment-assessed-by-optical-coherence-tomography-and-scheimpflug-device
#18
J I Fernández-Vigo, L de-Pablo Gómez de Liaño, I Sánchez-Guillen, A Macarro-Merino, C Fernández-Vigo, J García-Feijóo, J A Fernández-Vigo
OBJECTIVE: To evaluate different anterior segment parameters in eyes with pseudoexfoliation (PSX), fellow eyes, and controls using optical coherence tomography and a Scheimpflug imaging system. METHODS: Three groups were studied: 44 eyes of 44 patients with PSX, 30 clinically unaffected fellow eyes, and 148 eyes of 148 healthy controls. The anterior chamber depth and volume, corneal volume and thickness, pupil diameter and corneal densitometry were measured using a Scheimpflug imaging system (Pentacam, Oculus Inc...
July 22, 2017: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/28740145/validation-of-asynchronous-quantitative-bone-densitometry-of-the-spine-accuracy-short-term-reproducibility-and-a-comparison-with-conventional-quantitative-computed-tomography
#19
Ling Wang, Yongbin Su, Qianqian Wang, Yangyang Duanmu, Minghui Yang, Chen Yi, Xiaoguang Cheng
Asynchronous calibration quantitative computed tomography (QCT) is a new tool that allows the quantification of bone mineral density (BMD) without the use of a calibration phantom during scanning; however, this tool is not fully validated for clinical use. We used the European spine phantom (ESP) with repositioning during scanning and assessed the accuracy and short-term reproducibility of asynchronous QCT. Intra-scanner and intra-observer precision were each calculated as the root mean square of the standard deviation (RMSSD) and the coefficient of variation (CV-RMSSD)...
July 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28739082/osteoporosis-risk-calculators
#20
Beatrice J Edwards
Osteoporosis is a silent disease until fractures occur, patient recognition is the greatest clinical challenge. Although more than 20 million women in the US are estimated to have established osteoporosis the majority are not appropriately identified. Bone densitometry is the current gold standard for diagnosis of osteoporosis; but may not be feasible or cost-effective to recommend for all postmenopausal women. Therefore, questionnaires incorporating risk factors have been developed to aid the clinician in identifying women with osteoporosis...
July 2017: Journal of Clinical Densitometry
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