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Clinical Densitometry

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https://www.readbyqxmd.com/read/29681439/bone-mineral-density-distribution-curves-in-spanish-adults-with-down-syndrome
#1
Ramón Costa, Alejandra Gullón, Rosa De Miguel, Diego Real de Asúa, Azucena Bautista, Clara García, Carmen Suarez, Santos Castañeda, Fernando Moldenhauer
According to reports from small-sized case series, adults with Down syndrome (DS) appear to have lower bone mineral density (BMD) than the general population. The objective of our study was to further characterize the bone mass acquisition curve in an adult DS population. This is a retrospective study of 297 adults with DS from the Adult Down Syndrome Outpatient Clinic of a tertiary care hospital in Madrid, Spain, who underwent a bone densitometry (Hologic QDR-4500W), for clinical purposes between January 2010 and June 2015...
March 21, 2018: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/29675043/cardiovascular-risk-factors-after-childhood-cancer-treatment-are-independent-of-the-fto-gene-polymorphism
#2
Małgorzata Sawicka-Żukowska, Maryna Krawczuk-Rybak, Paweł Bernatowicz, Katarzyna Muszyńska-Rosłan, Jerzy Konstantynowicz, Włodzimierz Łuczyński
The study objective was to assess the prevalence of cardiovascular disease risk factors in patients treated for childhood cancer ( N = 101) and to determine the involvement of clinical (cancer type and therapy) and/or genetic ( FTO gene rs9939609 polymorphism) factors. Anthropometric features, laboratory findings, and standardized osteodensitometric indices (fat and lean mass) were considered. Overweight/obesity was found in 17.82% of the patients; however, central adiposity was found in as many as 42.5%. At least one abnormality in lipid metabolism was observed in 35...
2018: International Journal of Endocrinology
https://www.readbyqxmd.com/read/29664757/primary-hyperparathyroidism-recent-advances
#3
Marcella D Walker, John P Bilezikian
PURPOSE OF REVIEW: The purpose of this review is to describe recent advances and changes in the evaluation and management of primary hyperparathyroidism (PHPT). RECENT FINDINGS: Although it has long been recognized that asymptomatic PHPT is associated with bone loss, particularly at cortical skeletal sites when evaluated with dual-energy X-ray absorptiometry, new imaging techniques suggest that trabecular skeletal deterioration as well as clinically silent vertebral fractures and nephrolithiasis are common...
April 13, 2018: Current Opinion in Rheumatology
https://www.readbyqxmd.com/read/29661688/effect-of-positioning-of-the-roi-on-bmd-of-the-forearm-and-its-subregions
#4
Elizabeth O Rosen, Elizabeth A McNamara, LaTarsha G Whittaker, Alan O Malabanan, Harold N Rosen
Inconsistent positioning of patients and region of interest (ROI) is known to influence the precision of bone mineral density (BMD) measurements in the spine and hip. However, it is unknown whether minor shifts in the positioning of the ROI along the shaft of the radius affect the measurement of forearm BMD and its subregions. The ultradistal (UD-), mid-, one-third, and total radius BMDs of 50 consecutive clinical densitometry patients were acquired. At baseline the distal end of the ROI was placed at the tip of the ulnar styloid as usual, and then the forearm was reanalyzed 10 more times, each time shifting the ROI 1 mm proximally...
March 21, 2018: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/29649091/the-prognostic-significance-of-pedicle-enhancement-from-contrast-enhanced-mri-for-the-further-collapse-in-osteoporotic-vertebral-compression-fractures
#5
Sung Eun Hyun, Jin Young Ko, Eugene Lee, Ju Seok Ryu
STUDY DESIGN: Retrospective observational study. OBJECTIVE: The aim of this study was to investigate the prognostic significance of contrast-enhanced MRI for detecting pedicle enhancement and predicting future collapse in patients with acute benign osteoporotic vertebral compression fracture (OVCF). SUMMARY OF BACKGROUND DATA: Traditional morphological classification regarding compression versus burst fractures cannot accurately anticipate the prognosis of further collapse...
April 11, 2018: Spine
https://www.readbyqxmd.com/read/29615834/corneal-clarity-measurements-in-patients-with-keratoconus-undergoing-either-penetrating-or-deep-anterior-lamellar-keratoplasty
#6
Khaled Alzahrani, Syarifah-Faiza Dardin, Fiona Carley, Arun Brahma, Debbie Morley, M Chantal Hillarby
Purpose: To compare the corneal clarity measurement between penetrating keratoplasty (PK) and deep anterior lamellar keratoplasty (DALK) in patients with keratoconus, using densitometry software for the Oculus Pentacam. Methods: A retrospective comparative study was carried out at Manchester Royal Eye Hospital. Data were collected 12-18 months after corneal transplantation for keratoconus, including postoperative corneal densitometry, best corrected visual acuity (BCVA), central corneal thickness (CCT), and other relevant clinical details...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29605092/evaluation-of-a-vaccination-regimen-and-care-in-relation-to-follow-up-and-treatment-of-patients-with-inflammatory-bowel-disease
#7
J K Yamamoto-Furusho, A Sarmiento-Aguilar, N N Parra-Holguín, K E Bozada-Gutiérrez
INTRODUCTION AND AIMS: During the clinical course of inflammatory bowel disease, different causes can compromise kidney, liver, and bone marrow function and increase the risk for osteoporosis, infections, and neoplasias. The aim of the present study was to describe the follow-up of Mexican patients with inflammatory bowel disease in relation to their vaccination regimen, treatment-associated risks, and cancer screening. MATERIALS AND METHODS: A retrospective cross-sectional study was conducted within the time frame of February and June 2017...
March 28, 2018: Revista de Gastroenterología de México
https://www.readbyqxmd.com/read/29567290/effects-of-curcumin-on-bone-loss-and-biochemical-markers-of-bone-turnover-in-patients-with-spinal-cord-injury
#8
Masoud Hatefi, Mohammad Reza Hafezi Ahmadi, Asghar Rahmani, Masoud Moghadas Dastjerdi, Khairollah Asadollahi
BACKGROUND: Osteoporosis is one of the most common problems of patients with spinal cord injuries (SCI). The current study aimed to evaluate the anti-osteoporotic effects of Curcumin on densitometry parameters and biomarkers of bone turnovers among patients with SCI. MATERIALS AND METHODS: The current controlled clinical trial was conducted among 100 patients with SCI referred to an Outpatient Clinic of Rehabilitation in Ilam city, Iran in 2013-2015. Intervention group received 110/mg/kg/day Curcumin for six months and control group received placebo...
March 19, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29551009/assessment-of-physical-performance-and-body-composition-in-male-renal-transplant-patients
#9
Andrea Petronio Rossi, Gianluigi Zaza, Marina Zanardo, Francesco Pedelini, Laura Dalla Verde, Chiara Caletti, Alessia D'Introno, Antonio Lupo, Mauro Zamboni
BACKGROUND: Renal transplant (RTX) recipients seem to experience a better quality of life compared to dialysis patients. However, the factors responsible for this positive effect are not completely defined. Conceivably, a change in the physical performance of these patients could play a role. METHODS: To assess this, we measured: (1) waist circumference, fat mass and appendicular fat-free mass (aFFM) by dual-energy X-ray densitometry, (2) physical performance with the Short Physical Performance Battery, and (3) muscle strength with the handgrip test, in 59 male RTX, 11 chronic kidney disease in conservative treatment (CKD) and 10 peritoneal dialysis (PD) patients...
March 17, 2018: Journal of Nephrology
https://www.readbyqxmd.com/read/29549461/assessment-of-corneal-backward-light-scattering-in-the-healthy-cornea-and-factors-affecting-corneal-transparency
#10
Ali Bulent Cankaya, Kemal Tekin, Hasan Kiziltoprak, Sevilay Karahan, Pelin Yilmazbas
PURPOSE: To quantify normative corneal optical density (COD) values of healthy individuals and to investigate alterations in the COD in relation to their ocular and demographic characteristics. STUDY DESIGN: Prospective, cross-sectional, and observational. METHODS: In total, 588 eyes from 588 healthy participants with clear corneas were consecutively enrolled. Corneal densitometry values expressed in standardized grayscale units (GSU) from different corneal layers and zones obtained using the rotating Pentacam Scheimpflug system were analyzed...
March 16, 2018: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29537886/corneal-densitometry-after-femtosecond-laser-assisted-in-situ-keratomileusis-fs-lasik-and-small-incision-lenticule-extraction-smile
#11
Mehdi Shajari, Emanuel Wanner, Vladimir Rusev, Shervin Mir Mohi Sefat, Wolfgang J Mayer, Thomas Kohnen, Siegfried Priglinger, Daniel Kook
PURPOSE: To compare corneal densitometry values after Femtosecond Laser-Assisted In Situ Keratomileusis (Fs-LASIK) and Small Incision Lenticule Extraction (SMILE) using Scheimpflug Imaging. METHODS: Our retrospective clinical trial included a total of 146 eyes where 57 eyes underwent Fs-LASIK and 89 eyes underwent SMILE. Examinations with a Pentacam Scheimpflug device (Oculus, Wetzlar, Germany) were performed before surgery, 1 week, 1 month, 3 months, 6 months, and 1 year after surgery...
March 14, 2018: Current Eye Research
https://www.readbyqxmd.com/read/29520928/pbov1-as-a-potential-biomarker-for-more-advanced-prostate-cancer-based-on-protein-and-digital-histomorphometric-analysis
#12
Neil M Carleton, Guangjing Zhu, Mikhail Gorbounov, M Craig Miller, Kenneth J Pienta, Linda M S Resar, Robert W Veltri
BACKGROUND: There are few tissue-based biomarkers that can accurately predict prostate cancer (PCa) progression and aggressiveness. We sought to evaluate the clinical utility of prostate and breast overexpressed 1 (PBOV1) as a potential PCa biomarker. METHODS: Patient tumor samples were designated by Grade Groups using the 2014 Gleason grading system. Primary radical prostatectomy tumors were obtained from 48 patients and evaluated for PBOV1 levels using Western blot analysis in matched cancer and benign cancer-adjacent regions...
March 9, 2018: Prostate
https://www.readbyqxmd.com/read/29480212/what-is-the-fracture-risk-in-patients-at-a-multidisciplinary-neuromuscular-clinic
#13
George J Francis, Amy E Cook, Donald W Morrish, K Ming Chan, Hernish J Acharya
Many neuromuscular diseases (NMD) result in muscle weakness, immobility and greater fracture risk. The objective of this study is to determine the fracture risk of adult patients at a multidisciplinary NMD clinic. Fracture risk was calculated using the Fracture Risk Assessment Tool, the presence of osteoporosis was quantified using bone densitometry and contributing co-morbidities were screened through serum markers. Of the 36 patients studied, 47% were found to be of moderate and high fracture risk. Two thirds of these patients had not been previously screened or treated for osteoporosis...
2018: Journal of Neuromuscular Diseases
https://www.readbyqxmd.com/read/29466058/consensus-statement-by-the-american-association-of-clinical-endocrinologists-and-american-college-of-endocrinology-on-the-quality-of-dxa-scans-and-reports
#14
Angelo A Licata, Neil Binkley, Steven M Petak, Pauline M Camacho
OBJECTIVE: High-quality dual-energy X-ray absorptiometry (DXA) scans are necessary for accurate diagnosis of osteoporosis and monitoring of therapy; however, DXA scan reports may contain errors that cause confusion about diagnosis and treatment. This American Association of Clinical Endocrinologists/American College of Endocrinology consensus statement was generated to draw attention to many common technical problems affecting DXA report conclusions and provide guidance on how to address them to ensure that patients receive appropriate osteoporosis care...
February 2018: Endocrine Practice
https://www.readbyqxmd.com/read/29445872/bowman-layer-transplantation-5-year-results
#15
Korine van Dijk, Jack S Parker, Lamis Baydoun, Abbas Ilyas, Isabel Dapena, Esther A Groeneveld-van Beek, Gerrit R J Melles
PURPOSE: The purpose of this study was to evaluate the 5-year clinical results of isolated Bowman layer (BL) transplantation in the treatment of advanced keratoconus. METHODS: In this prospective, single-center, interventional case series at a tertiary referral center, 20 eyes of 17 patients with advanced keratoconus underwent BL transplantation, i.e. an isolated Bowman layer graft was positioned into a manually dissected mid-stromal pocket. Scheimpflug-based corneal tomography measurements, best corrected spectacle and contact lens visual acuities (BSCVA and BCLVA), endothelial cell density, and complications were evaluated up to 5 years after surgery...
February 14, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29445272/ct-densitometry-in-emphysema-a-systematic-review-of-its-clinical-utility
#16
Diana Crossley, Mary Renton, Muhammad Khan, Emma V Low, Alice M Turner
Background: The aim of the study was to assess the relationship between computed tomography (CT) densitometry and routine clinical markers in patients with chronic obstructive pulmonary disease (COPD) and alpha-1 anti-trypsin deficiency (AATD). Methods: Multiple databases were searched using a combination of pertinent terms and those articles relating quantitatively measured CT densitometry to clinical outcomes. Studies that used visual scoring only were excluded, as were those measured in expiration only...
2018: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29429284/-clinical-observation-on-corneal-transparency-after-small-incision-lenticule-extraction-surgery
#17
L Zhang, Y Wang, T Cui, W Zhao, W B Cheng
Objective: To evaluate the changes of corneal transparency over the 1-year period after small incision lenticule extraction (SMILE) according to corneal Scheimpflug densitometry. Methods: Prospective cohort study. Fifty-five patients (100 eyes) with myopia (19 male and 36 female, aged 18 to 39 years with average of 24) who underwent SMILE and regular follow-up for at least 1 year at Tianjin Eye Hospital were enrolled. Examinations took place before SMILE and postoperatively at 1 day, 1 week, and 1, 3, 6, and 12 months...
January 11, 2018: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29396318/treatment-of-enucleated-odontogenic-jaw-cysts-a-systematic-review
#18
REVIEW
Mayte Buchbender, Friedrich W Neukam, Rainer Lutz, Christian M Schmitt
OBJECTIVES: In this systematic review, we aimed to assess the impact of filling or not filling enucleated odontogenic jaw cysts on bony defect consolidation. In terms of filling, we aimed to assess which is the best filling material based on current evidence. STUDY DESIGN: An electronic search was performed using PubMed, Embase, and MEDLINE databases with the logical operators: "odontogenic cysts" AND "jaw cysts" AND "treatment AND therapy...
December 29, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/29384807/an-early-finding-of-keratoconus-increase-in-corneal-densitometry
#19
Mustafa Koc, Kemal Tekin, Merve Inanc Tekin, Mehmet Murat Uzel, Pinar Kosekahya, Kemal Ozulken, Pelin Yilmazbas
PURPOSE: To investigate the corneal densitometry in subclinical keratoconus with normal elevation and pachymetric parameters. METHODS: Patients with clinical keratoconus in one eye and subclinical keratoconus in the fellow eye were identified. The study group was selected from patients with subclinical keratoconus who showed normal results from topographic and Belin-Ambrósio Enhanced Ectasia Display III (BAD) analysis (Kmean <47.2 diopters, inferior-superior asymmetry <1...
January 30, 2018: Cornea
https://www.readbyqxmd.com/read/29350509/measuring-overuse-with-electronic-health-records-data
#20
Thomas Isaac, Meredith B Rosenthal, Carrie H Colla, Nancy E Morden, Alexander J Mainor, Zhonghe Li, Kevin H Nguyen, Elizabeth A Kinsella, Thomas D Sequist
OBJECTIVES: To measure overuse of low-value care using electronic health record (EHR) data and manual chart review and to evaluate whether certain low-value services are better captured using EHR data. STUDY DESIGN: We implemented algorithms to extract performance on 13 Choosing Wisely-identified healthcare services using EHR data at a large physician practice group between 2011 and 2013. METHODS: We calculated rates of overuse using automated EHR extracts...
January 2018: American Journal of Managed Care
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