Jiemei Yang, Penghao Gao, Qiannan Li, Tengyu Wang, Shuyuan Guo, Jingyu Zhang, Tianyi Zhang, Guodong Wu, Yuanyuan Guo, Zeng Wang, Ye Tian
OBJECTIVE: Arterial adventitial vasa vasorum (AVV) plays an important role in the occurrence and development of atherosclerotic (AS) disease. AS is a systemic disease, and plaque is not only a local vascular event, but also occurs at multiple sites throughout the vascular bed. Currently, effective anti-AVV therapies are lacking. Therefore, we posed the following scientific questions: "does human carotid adventitial vasa vasorum density reflect plaque neovascularization and intimal-media hyperplasia in carotid?"; and "is it possible to reduce human AVV density by sonodynamic therapy (SDT)?" METHODS: A retrospective study was conducted on 160 patients with carotid atherosclerosis...
February 15, 2024: Ultrasound in Medicine & Biology