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https://www.readbyqxmd.com/read/27900734/lithium-side-effects-and-toxicity-prevalence-and-management-strategies
#1
REVIEW
Michael Gitlin
Despite its virtually universal acceptance as the gold standard in treating bipolar disorder, prescription rates for lithium have been decreasing recently. Although this observation is multifactorial, one obvious potential contributor is the side effect and toxicity burden associated with lithium. Additionally, side effect concerns assuredly play some role in lithium nonadherence. This paper summarizes the knowledge base on side effects and toxicity and suggests optimal management of these problems. Thirst and excessive urination, nausea and diarrhea and tremor are rather common side effects that are typically no more than annoying even though they are rather prevalent...
December 2016: International Journal of Bipolar Disorders
https://www.readbyqxmd.com/read/27899986/metastasis-of-renal-cell-carcinoma-to-the-parathyroid-gland-16-years-after-radical-nephrectomy-a-case-report
#2
Liborio Torregrossa, Maria Isabella Rotondo, Andrea Cacciato Insilla, David Galleri, Federica Guidoccio, Paolo Miccoli, Virginia A Livolsi, Fulvio Basolo
Renal cell carcinoma (RCC) has a high metastatic potential, and most commonly metastasizes via the bloodstream, although lymphatic metastases also occur. RCC is well-known for its propensity to metastasize to unusual sites, and late metastasis, even after a number of years, is common. The occurrence of RCC metastasis to the head and neck region is uncommon, and occurs primarily in the thyroid gland and in patients with widespread dissemination. Involvement of the parathyroid gland in metastatic carcinoma is extremely rare...
November 2016: Oncology Letters
https://www.readbyqxmd.com/read/27896436/risk-factors-for-complications-after-adrenalectomy-results-from-a-comprehensive-national-database
#3
Lo Hallin Thompson, Erik Nordenström, Martin Almquist, Helene Jacobsson, Anders Bergenfelz
PURPOSE: Most knowledge regarding outcome after adrenal surgery stems from retrospective studies reported by highly specialized centres. The aim of this study was to report a national experience of adrenalectomy with particular attention to predictive factors for postoperative complications, conversion from endoscopic to open surgery and length of hospital stay. METHODS: Adrenalectomies reported in the Scandinavian Quality Register for Thyroid, Parathyroid and Adrenal Surgery (SQRTPA) 2009-2014 were included...
November 28, 2016: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/27895879/evaluation-of-stress-scores-throughout-radiological-biopsies
#4
Ozlem Turkoglu, Hasan Huseyin Mutlu
BACKGROUND: Ultrasound-guided biopsy procedures are the most prominent methods that increase the trauma, stress and anxiety experienced by the patients. OBJECTIVES: Our goal was to examine the level of stress in patients waiting for radiologic biopsy procedures and determine the stress and anxiety level arising from waiting for a biopsy procedure. PATIENTS AND METHODS: This prospective study included 35 female and 65 male patients who were admitted to the interventional radiology department of Kartal Dr...
October 2016: Iranian Journal of Radiology: a Quarterly Journal Published By the Iranian Radiological Society
https://www.readbyqxmd.com/read/27885739/analysis-of-factors-affecting-outcome-of-ultrasound-guided-radiofrequency-heat-ablation-for-treatment-of-primary-hyperparathyroidism-in-dogs
#5
Daniel Bucy, Rachel Pollard, Richard Nelson
Radiofrequency (RF) parathyroid ablation is a noninvasive treatment for hyperparathyroidism in dogs. There are no published data assessing factors associated with RF parathyroid ablation success or failure in order to guide patient selection and improve outcome. The purpose of this retrospective analytical study was to determine whether imaging findings, biochemical data, or concurrent diseases were associated with RF heat ablation treatment failure. For inclusion in the study, dogs must have had a clinical diagnosis of primary hyperparathyroidism, undergone cervical ultrasound and RF ablation of abnormal parathyroid tissue, and must have had at least 3 months of follow-up information available following the date of ultrasound-guided parathyroid ablation...
November 24, 2016: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/27867896/synchronous-parathyroid-adenoma-and-papillary-thyroid-cancer-detected-on-99m-tc-sestamibi-scintigraphy
#6
Sameer Kamalakar Taywade, Nishikant A Damle, Madhavi Tripathi, Shipra Agarwal, Sameer Aggarwal
No abstract text is available yet for this article.
November 2016: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27867866/indocyanine-green-enhanced-fluorescence-for-assessing-parathyroid-perfusion-during-thyroidectomy
#7
REVIEW
Matteo Lavazza, Xiaoli Liu, Chewei Wu, Angkoon Anuwong, Hoon Yub Kim, Renbin Liu, Gregory W Randolph, Davide Inversini, Luigi Boni, Stefano Rausei, Francesco Frattini, Gianlorenzo Dionigi
Identification of the parathyroid glands during thyroid surgery may prevent their inadvertent surgical removal and thus provide a better postoperative quality of life. Nevertheless, the most common "technique" for intraoperative evaluation of perfusion of parathyroid gland tissues during thyroid surgery is visual inspection of the physical condition of tissues, e.g., their color and bleeding edges. Another technique is measurement of intact parathyroid hormone. Recently, indocyanine green-enhanced fluorescence has been used in various surgical techniques, particularly laparoscopic surgery, to improve visualization and to provide detailed anatomical information...
October 2016: Gland Surgery
https://www.readbyqxmd.com/read/27867861/intraoperative-neural-monitoring-in-thyroid-surgery-lessons-learned-from-animal-studies
#8
REVIEW
Che-Wei Wu, Gregory W Randolph, I-Cheng Lu, Pi-Ying Chang, Yi-Ting Chen, Pao-Chu Hun, Yi-Chu Lin, Gianlorenzo Dionigi, Feng-Yu Chiang
Recurrent laryngeal nerve (RLN) injury remains a significant morbidity associated with thyroid and parathyroid surgery. In the past decade, surgeons have increasingly used intraoperative neural monitoring (IONM) as an adjunct technique for localizing and identifying the RLN, detecting RLN injury, and predicting the outcome of vocal cord function. In recent years, many animal studies have investigated common pitfalls and new applications of IONM. For example, the use of IONM technology in animal models has proven valuable in studies of the electrophysiology of RLN injury...
October 2016: Gland Surgery
https://www.readbyqxmd.com/read/27865592/parathyroidectomy-for-primary-hyperparathyroidism-improves-sleep-quality-a-prospective-study
#9
Justin La, Tracy S Wang, Abdulrahman Y Hammad, Laura Burgardt, Kara Doffek, Azadeh A Carr, Joseph L Shaker, Ty B Carroll, Douglas B Evans, Tina W F Yen
BACKGROUND: This prospective survey study assessed changes in sleep quality in patients with primary hyperparathyroidism after parathyroidectomy. METHODS: Patients undergoing parathyroidectomy for primary hyperparathyroidism (n = 110) or thyroidectomy for benign euthyroid disease (control group; n = 45) were recruited between June 2013 and June 2015 and completed the Pittsburgh Sleep Quality Index preoperatively and at 1- and 6 months postoperatively. "Poor" sleep quality was defined as a score >5; a clinically important and relevant improvement was a ≥3-point decrease...
November 16, 2016: Surgery
https://www.readbyqxmd.com/read/27864717/intraoperative-localization-of-the-parathyroid-glands-with-indocyanine-green-and-firefly-r-technology-during-baba-robotic-thyroidectomy
#10
Hyeong Won Yu, Joon Woo Chung, Jin Wook Yi, Ra-Yeong Song, Joon-Hyop Lee, Hyungju Kwon, Su-Jin Kim, Young Jun Chai, June Young Choi, Kyu Eun Lee
BACKGROUND: It is unclear whether near-infrared (NIR) light-induced indocyanine green (ICG) fluorescence can effectively identify, and thus permit the preservation of, parathyroid glands in bilateral axillo-breast approach (BABA) robotic thyroidectomy. This case-control study with a prospectively recruited consecutive series and a retrospectively selected control group assessed the usefulness of ICG with Firefly(R) technology to identify the parathyroid glands intraoperatively during BABA robotic thyroidectomy...
November 18, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27861939/changes-in-electromyographic-amplitudes-but-not-latencies-occur-with-endotracheal-tube-malpositioning-during-intraoperative-monitoring-for-thyroid-surgery-implications-for-guidelines
#11
Samuel R Barber, Whitney Liddy, Natalia Kyriazidis, Matteo Cinquepalmi, Brian M Lin, Rahul Modi, Stephanie Patricio, Dipti Kamani, Carlo Belotti, Sadhana Mahamad, Bradley Lawson, Gregory W Randolph
OBJECTIVES/HYPOTHESIS: During intraoperative neural monitoring (IONM) in thyroid and parathyroid surgery, endotracheal (ET) tube migration can result in a decrease in vocalis electromyographic (EMG) amplitude without a concordant latency elevation during stimulation of the recurrent laryngeal nerve (RLN). STUDY DESIGN: Retrospective review. METHODS: Data were reviewed retrospectively for thyroid and parathyroid surgery patients with IONM of the laryngeal nerves from January 2015 to December 2015...
November 16, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27861937/electrophysiological-identification-of-nonrecurrent-laryngeal-nerves
#12
Emad Kandil, Muhammad A Anwar, Jeremy Bamford, Rizwan Aslam, Gregory W Randolph
OBJECTIVES/HYPOTHESIS: The nonrecurrent laryngeal nerve (NRLN) is a common anatomic variation of the right recurrent laryngeal nerve (RLN), which has been associated with an increased risk of injury during thyroid and parathyroid surgery. We suggest that early successful identification using intraoperative nerve monitoring (IONM) and preservation of this variant will help the surgeon to avoid injury to this nerve. Our objective was to examine the electrophysiological parameters of the NRLN and the efficacy of IONM for successful identification of the NRLN...
November 15, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27861338/enhanced-identification-and-functional-protective-role-of-carbon-nanoparticles-on-parathyroid-in-thyroid-cancer-surgery-a-retrospective-chinese-population-study
#13
Chenlei Shi, Bo Tian, Shengze Li, Tiefeng Shi, Huadong Qin, Shaoyan Liu
The aim of this study was to determine the effects of nanocarbon particles in combination with meticulous capsular dissection on enhancing the identification and protecting the function of parathyroid glands in thyroid cancer surgery.The data of 97 patients with papillary thyroid tumors diagnosed and treated at the Second Affiliated Hospital, Harbin Medical University between January 2014 and February 2015 were reviewed. Data regarding the sex, age, calcium and parathyroid hormone (PTH) levels, tumor size, multifocality, T stage, and extrathyroid invasion were collected...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27857512/respiratory-manifestations-in-endocrine-diseases
#14
REVIEW
Codruţa Lencu, Teodora Alexescu, Mirela Petrulea, Monica Lencu
The control mechanisms of respiration as a vital function are complex: voluntary - cortical, and involuntary - metabolic, neural, emotional and endocrine. Hormones and hypothalamic neuropeptides (that act as neurotrasmitters and neuromodulators in the central nervous system) play a role in the regulation of respiration and in bronchopulmonary morphology. This article presents respiratory manifestations in adult endocrine diseases that evolve with hormone deficit or hypersecretion. In hyperthyroidism, patients develop ventilation disorders, obstructive and central sleep apnea, and pleural collection...
2016: Clujul Medical (1957)
https://www.readbyqxmd.com/read/27852814/spontaneous-proliferative-and-neoplastic-lesions-in-thyroid-and-parathyroid-glands-of-nondomestic-felids
#15
Jenny P Pope, James Steeil, Edward C Ramsay, Danielle Reel, Shelley J Newman
Based on microscopic and immunohistochemical characterization, we documented spontaneous proliferative and neoplastic lesions in the thyroid and parathyroid glands of nondomestic felids. Ten animals (4 leopards, 3 tigers, and 3 cougars), all with a previous diagnosis of thyroid neoplasia were identified from the University of Tennessee College of Veterinary Medicine database. The mean age of affected animals was 15.9 y. Twelve neoplasms were identified; 2 animals had 2 concurrent neoplasms. After immunohistochemical characterization using a panel of chromogranin A, thyroglobulin, and calcitonin, 7 of the former thyroid neoplasms were diagnosed as thyroid adenomas, 1 was diagnosed as a thyroid carcinoma, and 4 were diagnosed as parathyroid adenomas...
November 15, 2016: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/27846184/minimal-endoscope-assisted-thyroidectomy-through-a-retroauricular-approach-an-evolving-solo-surgery-technique
#16
Myung Jin Ban, Jae Won Chang, Won Shik Kim, Hyung Kwon Byeon, Yoon Woo Koh, Jae Hong Park
This study aimed to evaluate the feasibility and efficacy of minimal endoscope-assisted thyroidectomy (MEAT) through a retroauricular (RA) approach. Most of the thyroidectomy operative time was accounted for by direct visualization through the RA window, minimizing interference between surgical instruments. Endoscope use was minimized and limited to critical surgical aspects, including preservation of the recurrent laryngeal nerve and parathyroid glands. The recurrent laryngeal nerve was neuromonitored throughout the procedure...
November 11, 2016: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/27846041/factors-affecting-the-sensitivity-of-tc-99m-methoxyisobutylisonitrile-dual-phase-parathyroid-single-photon-emission-computed-tomography-in-primary-hyperparathyroidism
#17
Mine Araz, Derya Çayir, Mehmet Erdoğan, Bekir Uçan, Erman Çakal
OBJECTIVE: The aim of this study was to investigate the effects of thyroid diseases and regularly used medications on the sensitivity of Tc-99m methoxyisobutylisonitrile (MIBI) dual-phase parathyroid single photon emission computed tomography (SPECT) and to define indicatives of the result of the study. PATIENTS AND METHODS: Overall, 218 primary hyperparathyroidism patients (190 women, 28 men, mean age: 57±14 years) with thyroid-parathyroid ultrasonography and Tc-99m MIBI dual-phase parathyroid SPECT were retrospectively enrolled...
November 11, 2016: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/27844237/intraoperative-near-infrared-autofluorescence-imaging-of-parathyroid-glands
#18
Roland Ladurner, Sandra Sommerey, Nora Al Arabi, Klaus K J Hallfeldt, Herbert Stepp, Julia K S Gallwas
OBJECTIVE: To identify parathyroid glands intraoperatively by exposing their autofluorescence using near-infrared light. METHODS: Fluorescence imaging was carried out during minimally invasive and open parathyroid and thyroid surgery. After identification, the parathyroid glands as well as the surrounding tissue were exposed to near-infrared (NIR) light with a wavelength of 690-770 nm using a modified Karl Storz near-infrared/indocyanine green (NIR/ICG) endoscopic system...
November 14, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27834132/surgical-management-of-medullary-thyroid-carcinoma-in-pediatric-age
#19
Claudio Spinelli, Leonardo Rossi, Silvia Strambi, Jessica Piscioneri, Rossella Elisei, Maura Massimino, Paolo Miccoli
Medullary thyroid carcinoma (MTC) is a rare, accounting for 5% of thyroid malignancies. It is a neuroendocrine tumor wich origins from thyroid parafollicular cells. It may be sporadic, mostly in adult patients, or inherited as autosomal dominant pattern, mostly in pediatric patients. As familial cancer, MTC may presented isolated as familial medullary thyroid carcinoma (FMTC) - 10% of cases - or, most often, as part of multiple endocrine neoplasm type 2 (MEN 2A or MEN 2B) syndromes - 90% of cases. The therapy for sporadic or hereditary MTC is surgical resection and consists in total thyroidectomy associated with central compartment lymph nodal dissection; the radicality of this intervention is fundamental to obtain a definitive cure...
November 11, 2016: Current Pediatric Reviews
https://www.readbyqxmd.com/read/27834016/is-c-11-methionine-pet-ct-able-to-localise-sestamibi-negative-parathyroid-adenomas
#20
Theresia Weber, Martin Gottstein, Sabrina Schwenzer, Ambros Beer, Markus Luster
BACKGROUND: Patients with primary hyperparathyroidism (pHPT) and a negative preoperative Tc-99 sestamibi (MIBI) scintigraphy are considered to have a higher risk of persistent disease. The aim of this study was to assess whether additional imaging with C-11 methionine positron emission tomography/computed tomography (Met-PET/CT) is able to localise sestamibi-negative hyperfunctioning parathyroid glands. METHODS: In 50 patients (38 females, 12 males, age 13-81 years) with pHPT and negative localisation procedures such as ultrasound and sestamibi, a Met-PET/CT was performed before parathyroid surgery...
November 10, 2016: World Journal of Surgery
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