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https://www.readbyqxmd.com/read/28719612/renal-osteodystrophy-in-the-obesity-era-is-metabolic-syndrome-relevant
#1
Janaina Da Silva Martins, João Henrique Castro, Nestor A Sainz Rueda, Luciene Machado Dos Reis, Vanda Jorgetti, Rosa Maria Affonso Moysés, Jacqueline Teixeira Caramori
BACKGROUND: Observational studies have shown a beneficial effect of obesity on bone health; however, most of those studies were not based on bone biopsies. Metabolic syndrome (MetS) could have an effect on bone remodeling. However, there are no data on the effects of MetS in the presence of renal osteodystrophy. OBJECTIVE: The aim of this study was to investigate associations between MetS and renal osteodystrophy using the bone histomorphometric turnover-mineralization-volume (TMV) classification...
2017: PloS One
https://www.readbyqxmd.com/read/28713236/modulation-of-calcitonin-parathyroid-hormone-and-thyroid-hormone-secretion-by-electrical-stimulation-of-sympathetic-and-parasympathetic-nerves-in-anesthetized-rats
#2
Harumi Hotta, Akiko Onda, Harue Suzuki, Philip Milliken, Arun Sridhar
The thyroid and parathyroid glands are dually innervated by sympathetic (cervical sympathetic trunk [CST]) and parasympathetic (superior laryngeal nerve [SLN]) nerve fibers. We examined the effects of electrical stimulation of efferent or afferent nerve fibers innervating the thyroid and parathyroid glands on the secretion of immunoreactive calcitonin (iCT), parathyroid hormone (iPTH), 3,3',5-triiodothyronine (iT3), and thyroxine (iT4) from the thyroid and parathyroid glands. In anesthetized and artificially ventilated rats, thyroid venous blood was collected...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28688695/transoral-thyroidectomy-and-parathyroidectomy-a-north-american-series-of-robotic-and-endoscopic-transoral-approaches-to-the-central-neck
#3
Jonathon O Russell, James Clark, Salem I Noureldine, Angkoon Anuwong, Mai G Al Khadem, Hoon Yub Kim, Vaninder K Dhillon, Gianlorenzo Dionigi, Ralph P Tufano, Jeremy D Richmon
OBJECTIVE: Most thyroid surgery in North America is completed via a cervical incision, which leaves a permanent scar. Approaches without cutaneous incisions offer aesthetic advantages. This series represents the largest series of transoral vestibular approaches to the central neck in North America, and the first published reports of robotic transoral vestibular thyroidectomy for thyroid carcinoma. MATERIALS AND METHODS: Data was prospectively collected for patients that underwent transoral vestibular approach thyroidectomy and/or parathyroidectomy between April 2016 and February 2017...
August 2017: Oral Oncology
https://www.readbyqxmd.com/read/28680641/concurrent-intrathyroidal-thymus-and-parathyroid-in-a-patient-with-papillary-thyroid-carcinoma-a-challenging-diagnosis
#4
Georgios Velimezis, Argyrios Ioannidis, Sotirios Apostolakis, Maria Chorti, Charalampos Avramidis, Evripidis Papachristou
During embryogenesis, the thymus and inferior parathyroid glands develop from the third pharyngeal pouch and migrate to their definite position. During this process, several anatomic variations may arise, with the thyroid being one of the most common sites of ectopic implantation for both organs. Here, we report the case of a young female patient, who underwent total thyroidectomy for papillary carcinoma of the thyroid. The patient's history was remarkable for disorders of the genitourinary system. Histologic examination revealed the presence of well-differentiated intrathyroidal thymic tissue, containing an inferior parathyroid gland...
2017: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/28680214/ectopic-parathyroid-incidentaloma-on-tc99m-sestamibi-myocardial-perfusion-imaging
#5
Rola Aatif Hasan Hussain, Ammar Mohammed Saeed Ali, K Manivannan, S K Chirala
Parathyroid incidentalomas are generally discovered during thyroid surgery.([1]) In the present case, the ectopic parathyroid adenoma was discovered as an incidentaloma in a clinical setting, during the course of clinical evaluation of atypical chest pain by gastroenterology and cardiology.
July 2017: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/28658330/transaxillary-single-port-subtotal-parathyroidectomy-feasibility-study-in-cadavers
#6
Alexandre Elmães de Marsillac, Rossano Kepler Alvim Fiorelli, Henrique Neubarth Phillips, Pietro Novellino, André Lacerda Oliveira, Ricardo Paiva A Scheiba Zorron
Objective : to test the minimally invasive technique of single-port transaxillary subtotal parathyroidectomy in non-formalized cadavers to evaluate its viability and reproduction. Method : we performed ten subtotal parathyroidectomies through a transaxillary TriPort access in cadavers. The technique consisted of access through the axillary fossa, creating a subcutaneous tunnel to the anterior cervical region, for handling of the thyroid gland and dissection and resection of the parathyroid glands...
March 2017: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/28656592/percentage-arterial-enhancement-an-objective-index-for-accurate-identification-of-parathyroid-adenoma-hyperplasia-in-primary-hyperparathyroidism
#7
Manjunath Goroshi, Anurag R Lila, Swati S Jadhav, Sushil Sonawane, Priya Hira, Shettepppa Goroshi, Mahadev N Garle, Abhay Dalvi, Pragati Sathe, Tushar R Bandgar, Nalini S Shah
BACKGROUND: Radiation exposure to neck by 4DCT is relatively high and limits its use as a first line investigation in evaluation of PHPT. Radiation exposure can be reduced by restricting the number of CT phases. Our aim was to study the performance of 4DCT in cohort of surgery-naïve primary hyperparathyroidism(PHPT) patients, and to evaluate percentage enhancement as an objective radiological index to discriminate parathyroid lesions(adenoma/hyperplasia) from thyroid tissue and lymph nodes...
June 28, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28648877/a-rare-presentation-a-case-report-of-osseous-metaplasia-and-mature-bone-formation-in-a-follicular-adenoma-of-the-thyroid
#8
Nadia Aurora, Insia Hashmi, Subhasis Misra, Nail Aydin
INTRODUCTION: Cases of multinodular goiter, thyroid hyperplasia, follicular adenoma, papillary thyroid carcinoma, and anaplastic thyroid carcinoma have been reported with histopathologic findings of osseous metaplasia (OM), bone marrow metaplasia (BMM), ectopic bone formation (EBF), ossification, and extramedullary hematopoiesis (EMH). To date no report of a follicular adenoma with OM and mature EBF in the absence of EMH has been reported in the English language. PRESENTATION OF CASE: 63-year-old woman with an incidental finding of thyroid nodule unable to be biopsied...
June 17, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28648505/hypothyroidism-associated-with-parathyroid-disorders
#9
REVIEW
Giovanna Mantovani, Francesca Marta Elli, Sabrina Corbetta
Hypothyroidism may occur in association with congenital parathyroid disorders determining parathyroid hormone insufficiency, which is characterized by hypocalcemia and concomitant inappropriately low secretion of parathormone (PTH). The association is often due to loss of function of genes common to thyroid and parathyroid glands embryonic development. Hypothyroidism associated with hypoparathyroidism is generally mild and not associated with goiter; moreover, it is usually part of a multisystemic involvement not restricted to endocrine function as occurs in patients with 22q11 microdeletion/DiGeorge syndrome, the most frequent disorders...
March 2017: Best Practice & Research. Clinical Endocrinology & Metabolism
https://www.readbyqxmd.com/read/28644425/significance-of-parathyroid-scintigraphy-and-correlation-of-findings-with-parathyroid-hormone-values-in-patients-undergoing-hemodialysis
#10
Nermana Ahmetbegović, Nadira Suljagić, Vahidin Katica
Aim To compare finding of thyroid gland scintigraphy with serum concentration of parathyroid hormone in patients undergoing hemodialysis. Methods This retrospective-prospective study included 50 patients undergoing hemodialysis with established hyperparathyroidism who were treated at Cantonal Hospital Zenica in the period 2009 - 2014. Besides anthropological data, concentration of parathyroid hormone in serum of patients was monitored too. Scintigraphy was performed at the Department of Nuclear Medicine using two-headed gamma camera Prism 2000xp...
August 1, 2017: Medicinski Glasnik
https://www.readbyqxmd.com/read/28639211/selective-venous-sampling-for-primary-hyperparathyroidism-how-to-perform-an-examination-and-interpret-the-results-with-reference-to-thyroid-vein-anatomy
#11
REVIEW
Takayuki Yamada, Masaya Ikuno, Yasumoto Shinjo, Atsushi Hiroishi, Shoichiro Matsushita, Tsuyoshi Morimoto, Reiko Kumano, Kunihiro Yagihashi, Takuyuki Katabami
Primary hyperparathyroidism (pHPT) causes hypercalcemia. The treatment for pHPT is surgical dissection of the hyperfunctioning parathyroid gland. Lower rates of hypocalcemia and recurrent laryngeal nerve injury imply that minimally invasive parathyroidectomy (MIP) is safer than bilateral neck resection. Current trends in MIP use can be inferred only by reference to preoperative localization studies. Noninvasive imaging studies (typically preoperative localization studies) show good detection rates of hyperfunctioning glands; however, there have also been cases of nonlocalization or discordant results...
June 21, 2017: Japanese Journal of Radiology
https://www.readbyqxmd.com/read/28624166/retrograde-thyroidectomy-for-preservation-of-the-external-branch-of-the-superior-laryngeal-nerve-a-case-series
#12
Vijay Naraynsingh, Shamir Cawich, Dale Hassranah, Ravi Maharaj, Shariful Islam, Yardesh Singh
BACKGROUND: The external branch of the Superior Laryngeal nerve (EBSLN) is at high risk of injury in surgery for large multinodular goitre (MNG) since the upper pole is high in the neck, well cephalad to the EBSLN. We present a technique of drawing the lobe caudally by retrograde thyroidectomy in order to minimize nerve injury. DESIGN & METHOD: All patients having surgery for benign MNG were included. Cases with previous thyroid surgery, malignant and toxic disease were excluded...
May 15, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28621914/distinguishing-parathyroid-and-thyroid-lesions-on-ultrasound-guided-fine-needle-aspiration-a-correlation-of-clinical-data-ancillary-studies-and-molecular-analysis
#13
Margaret Cho, Thaira Oweity, Tamar C Brandler, Karen Fried, Pascale Levine
BACKGROUND: Differentiating parathyroid and thyroid lesions can be challenging because of considerable morphologic overlap and anatomic proximity. Therefore, the authors sought to identify characteristic morphologic patterns and useful adjunct tests to distinguish these 2 entities. METHODS: A search was conducted in the study institution database for clinically indeterminate thyroid nodules from 2000 through 2016 with an emphasis on confirmed parathyroid nodules...
June 16, 2017: Cancer
https://www.readbyqxmd.com/read/28614134/value-of-99mtc-mibi-spect-ct-parathyroid-imaging-and-ultrasonography-for-concomitant-thyroid-carcinoma
#14
Rui Guo, Jiqiu Wang, Min Zhang, Miao Zhang, Hongping Meng, Yifan Zhang, Biao Li
PURPOSE: We aimed to assess the frequency of carcinoma in cases with suspected parathyroid adenoma and test the value of Tc-methoxyisobutylisonitrile (Tc-MIBI) single-photon emission computed tomography/computed tomography (SPECT/CT) parathyroid imaging and neck ultrasonography in detecting concomitant thyroid carcinoma. PATIENTS AND METHODS: We enrolled 741 patients with clinically suspected parathyroid adenoma who underwent Tc-MIBI planer scans and SPECT/CT of the skull base, neck, and thorax; patients also underwent ultrasonography within 1 month before SPECT/CT...
August 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28602040/the-impact-of-a-head-and-neck-microvascular-fellowship-program-on-otolaryngology-resident-training
#15
Chad A Zender, Kate Clancy, Sami Melki, Shawn Li, Nicole Fowler
OBJECTIVE: To assess the impact of a microvascular head and neck (H&N) fellowship on senior residents' surgical experience. STUDY DESIGN: Retrospective review of Accreditation Council for Graduate Medical Education-generated operative case log reports, retrospective chart review, and electronic survey. METHODS: A retrospective review of one institution's residents' H&N operative case logs and free flap operative reports was performed to determine changes in key indicator cases (KICs) after the addition of a H&N fellowship...
June 11, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28585593/incidentaloma-from-general-practice-to-specific-endocrine-frame
#16
Ancuta Augustina Gheorghisan-Galateanu, Mara Carsote, Ana Valea
Incidentaloma, a modern concept connected to technology progress, represents an accidentally discovered tumour, usually used for hypophysis and adrenals, and rarely for thyroid, parathyroids, and ovaries. This is a narrative review based on PubMed research, between 2012 and 2016 focusing on general and endocrine approach and current controversies. Main dilemma is the terminology itself: randomly imagery finding is enough or non-functioning profile and low-growth rate (not requiring surgery) should be mandatory? The controversies refers to best time framing of re-scanning pituitary and adrenal incidentaloma and setting of clear criteria for subclinical Cushing's syndrome...
June 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28584743/benign-and-malignant-thyroid-gland-diseases-in-the-patients-with-primary-hyperparathyroidism
#17
Mehmet Celik, Sibel Guldiken, Semra Ayturk, Buket Yilmaz Bulbul, Ebru Tastekin, Nuray Can, Atakan Sezer, Funda Ustun, Ahmet Kucukarda
INTRODUCTION: This study aimed to evaluate concurrently detected thyroid pathologies in the patients who underwent surgery for primary hyperparathyroidism (PHPT). MATERIALS AND METHODS: In this study, we retrospectively analyzed the files of the patients who underwent surgery for PHPT between 2012 and 2015. Pre- and post-operative laboratory examination results and preoperative radiological and nuclear medicine findings of the patients were retrospectively recorded...
April 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/28578084/a-novel-surgical-strategy-for-secondary-hyperparathyroidism-purge-parathyroidectomy
#18
Cheng-Xiang Shan, Nian-Cun Qiu, Si-Luo Zha, Miao-E Liu, Qiang Wang, Pei-Pei Zhu, Zhi-Peng Du, Chun-Yan Xia, Ming Qiu, Wei Zhang
OBJECTIVE: This study was intended to demonstrate the feasibility and efficacy of purge parathyroidectomy (PPTX) for patients with secondary hyperparathyroidism (SHPT). METHODS: The "seed, environment, and soil" medical hypothesis was first raised, following review of the literatures, to demonstrate the possible causes of persistence or recurrence of SHPT after parathyroidectomy. Subsequently, the novel surgical strategy of PPTX was proposed, which involves comprehensive resection of the fibro-fatty tissues, including visible or invisible parathyroid, within the region surrounded by the thyroid cartilage, bilateral carotid artery sheath, and the brachiocephalic artery...
May 31, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28571792/papillary-carcinoma-of-the-thyroid-in-patients-with-primary-hyperparathyroidism-is-there-a-link
#19
M Beebeejaun, E Chinnasamy, P Wilson, A Sharma, N Beharry, G Bano
Primary hyperparathyroidism (PHPT) is present in up to 0.1% of the general population. The incidence is higher in women and increases with age. The majority of the cases is asymptomatic and up to 85% are due to single gland adenoma. Parathyroidectomy is the treatment of choice after localization of the hyperactive gland. Papillary Thyroid Carcinoma (PTC) is the most common cancer of the thyroid and constitutes more than 70% of thyroid malignancies. PTC can present as a single nodule or can be Multifocal. The incidence is higher in women...
June 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28569362/can-arfi-elastography-be-used-to-differentiate-parathyroid-from-thyroid-lesions
#20
A Chandramohan, M Therese, D Abhraham, T V Paul, P Jacob Mazhuvanchary
OBJECTIVES: To assess if elasticity score (ES) and shear wave velocity (SWV) measurement obtained using ARFI elastography can differentiate between parathyroid lesions and thyroid nodules. MATERIALS AND METHODS: ARFI elastography was performed on patients with primary hyperparathyroidism or solid thyroid nodules who were being considered for surgery using virtual touch quantification and virtual touch imaging (VTI) software. Only patients with surgical histopathology (47 parathyroid lesions, 38 benign thyroid nodules and 55 malignant thyroid nodules) were included for final analysis...
May 31, 2017: Journal of Endocrinological Investigation
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